Fasudil HCl (HA-1077)

Fasudil HCl is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM).
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Product Name Price Stock Qty
Fasudil HCl 250mg
Special Price $40.00 Regular Price $50.00
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Fasudil HCl 500mg
Special Price $60.00 Regular Price $75.00
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Adooq Products cited in reputable paper
Adooq's Fasudil HCl (HA-1077) has been cited by 9 publications
  • Seongjun So, .et al. , Int J Mol Sci, 2022, Dec 31;24(1):701 PMID: 36614165
  • Chengyu Xiang, .et al. , J Cardiovasc Transl Res, 2022, May 12 PMID: 35551627
  • Yeonmi Lee, .et al. , Commun Biol, 2022, Jan 25;5(1):95 PMID: 35079104
  • Jiwan Choi, .et al. , Stem Cell Res Ther, 2021, Nov 12;12(1):569
  • Jee Myung Yang, .et al. , Exp Mol Med, 2021, Apr;53(4):631-642 PMID: 33828232
  • Jooyoung Lee, .et al. , Cells, 2020, Jun; 9(6): 1521 PMID: 32580448
  • Kumar M, .et al. , Behav Brain Res, 2018, Oct 1;351:4-16 PMID: 29807069
  • Wei J, .et al. , Shock, 2018, Dec;50(6):706-713 PMID: 29283979
  • Hofni A, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2017, Aug;390(8):801-811 PMID: 28493050
  • Biological Activity
    Discription Fasudil HCl is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM).
    Targets
    Target Value
    Product Information
    Catalog Num A10381
    Formula C14H17N3O2S.HCl
    Molecular Weight 327.8
    CAS Number 105628-07-7
    SMILES C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
    Synonyms AT-877
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 5 mg/mL (15.25 mM)
    Water 60 mg/mL (183.02 mM)
    Ethanol Insoluble
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.51 mL 152.53 mL 305.06 mL
    0.5 mM 6.1 mL 30.51 mL 61.01 mL
    1 mM 3.05 mL 15.25 mL 30.51 mL
    5 mM 0.61 mL 3.05 mL 6.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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