FLI-06

Catalog No.: A13815

Gamma-secretase inhibitor

FLI-06

FLI-06 Chemical Structure

CAS NO. 313967-18-9

FLI-06 is a Notch inhibitor and the early secretory pathway inhibitor. FLI-06 disrupts the Golgi apparatus in a manner distinct from that of brefeldin A and golgicide A.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $225.00

Special Price $202.50

50 mg

Regular Price: $400.00

Special Price $360.00

100 mg

Regular Price: $700.00

Special Price $630.00

10mM * 1mL in DMSO

Regular Price: $130.00

Special Price $117.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

FLI-06 is a Notch inhibitor and the early secretory pathway inhibitor. FLI-06 disrupts the Golgi apparatus in a manner distinct from that of brefeldin A and golgicide A.
Targets
Notch
2.3 μM(EC50)
In vitro DMSO 88 mg/mL (200.67 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (18.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.8 mL 114.02 mL 228.04 mL
0.5 mM 4.56 mL 22.8 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.8 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13815
Actions Inhibitor
M. Wt 438.52
Formula C25H30N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 313967-18-9
Synonyms FLI06,FLI 06
SMILES CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4

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