Florifenine is a selective cyclooxygenase (COX) inhibitor that demonstrates significant anti-inflammatory activity. It effectively inhibits thromboxane B2 (TXB2) production in human whole blood with an IC50 value of 32.5 nM. Florifenine has been shown to reduce neutrophil migration and lower prostaglandin E2 (PGE2) levels in inflamed tissues, including ear edema and air pouch inflammation induced by Zymosan. This compound serves as a valuable tool for investigations in anti-inflammatory research.
Florifenine is a selective cyclooxygenase (COX) inhibitor that demonstrates significant anti-inflammatory activity. It effectively inhibits thromboxane B2 (TXB2) production in human whole blood with an IC50 value of 32.5 nM. Florifenine has been shown to reduce neutrophil migration and lower prostaglandin E2 (PGE2) levels in inflamed tissues, including ear edema and air pouch inflammation induced by Zymosan. This compound serves as a valuable tool for investigations in anti-inflammatory research.
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