Fmoc-N-amido-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, functioning primarily through click chemistry. This compound features an azide group that allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool in chemical biology research and therapeutic development.
Fmoc-N-amido-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, functioning primarily through click chemistry. This compound features an azide group that allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool in chemical biology research and therapeutic development.
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