HDAC6-IN-33 is a selective and irreversible inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 193 nM. This compound demonstrates a tight-binding affinity specifically for HDAC6, effectively inhibiting its activity through a two-step slow-binding mechanism. HDAC6-IN-33 is ideal for research applications aimed at studying the role of HDAC6 in various cellular processes and disease states, including neurodegeneration and cancer.
HDAC6-IN-33 is a selective and irreversible inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 193 nM. This compound demonstrates a tight-binding affinity specifically for HDAC6, effectively inhibiting its activity through a two-step slow-binding mechanism. HDAC6-IN-33 is ideal for research applications aimed at studying the role of HDAC6 in various cellular processes and disease states, including neurodegeneration and cancer.
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