HDAC8-IN-8 is a selective inhibitor of HDAC8, exhibiting IC50 values of 23.9 μM for human HDAC8 and 268.2 μM for snail HDAC8. Additionally, it demonstrates inhibitory effects on human HDAC1 and HDAC6, with IC50 values of 12.1 μM and 2.9 μM, respectively. This compound is particularly relevant for research on schistosomiasis and may be useful for studies focused on histone deacetylase modulation in various biological contexts.
HDAC8-IN-8 is a selective inhibitor of HDAC8, exhibiting IC50 values of 23.9 μM for human HDAC8 and 268.2 μM for snail HDAC8. Additionally, it demonstrates inhibitory effects on human HDAC1 and HDAC6, with IC50 values of 12.1 μM and 2.9 μM, respectively. This compound is particularly relevant for research on schistosomiasis and may be useful for studies focused on histone deacetylase modulation in various biological contexts.
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