Heptaibin

Catalog No.: A27308
Antifungal Antibiotic
Heptaibin is a peptaibol antifungal antibiotic that primarily targets fungal infections. It exhibits significant antimicrobial activity against Gram-positive bacteria, such as Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 8 μg/mL, and demonstrates effectiveness against various fungi including Aspergillus, Candida albicans, and Cryptococcus neoformans, with MIC values ranging from 13 to 32 μg/mL. Additionally, Heptaibin shows moderate activity against Rhabditella pseudoelongata, with an MIC of 50 μg/mL, making it a valuable reagent for research into antifungal treatments.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHeptaibin is a peptaibol antifungal antibiotic that primarily targets fungal infections. It exhibits significant antimicrobial activity against Gram-positive bacteria, such as Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 8 μg/mL, and demonstrates effectiveness against various fungi including Aspergillus, Candida albicans, and Cryptococcus neoformans, with MIC values ranging from 13 to 32 μg/mL. Additionally, Heptaibin shows moderate activity against Rhabditella pseudoelongata, with an MIC of 50 μg/mL, making it a valuable reagent for research into antifungal treatments.
Product Information
Catalog NumA27308
FormulaC76H118N16O19
Molecular Weight1559.85
CAS Number291311-47-2
SMILESO=C(N1[C@@H](C[C@H](C1)O)C(NC(C)(C)C(N[C@H](CO)CC2=CC=CC=C2)=O)=O)C(C)(C)NC([C@H](CCC(N)=O)NC([C@H]3N(C[C@@H](C3)O)C(C(C)(C)NC(C(C)(C)NC([C@H](CC(C)C)NC(CNC([C@H](C(C)C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@@H](NC(C)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
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