III-31-C

Name: III-31-C
Brand: Adooq Bioscience
SKU: A37269
Rating: 5 (288 reviews)

Catalog No.: A37269

γ-secretase Inhibitor

III-31-C is a hydroxyethyl urea-based inhibitor of γ-secretase. It demonstrates potent inhibition of amyloid-beta (Aβ) production, with an IC50 value of 10 nM in a cell-free γ-secretase assay and 200 nM in APP-transfected cells. This compound is relevant for research focused on Alzheimer's disease and offers valuable insights into the modulation of Aβ metabolism.

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III-31-C 398515-96-3 γ-secretase Inhibitor

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Biological Activity

Description	III-31-C is a hydroxyethyl urea-based inhibitor of γ-secretase. It demonstrates potent inhibition of amyloid-beta (Aβ) production, with an IC50 value of 10 nM in a cell-free γ-secretase assay and 200 nM in APP-transfected cells. This compound is relevant for research focused on Alzheimer's disease and offers valuable insights into the modulation of Aβ metabolism.

Product Information

Catalog Num	A37269
Formula	C35H52N4O7
Molecular Weight	640.81
CAS Number	398515-96-3
SMILES	O=C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(OC)=O)=O)N(C[C@@H](O)[C@@H](NC(OC(C)(C)C)=O)CC1=CC=CC=C1)CC2=CC=CC=C2

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