Imatinib (Gleevec)

Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.
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Product Name Price Stock Qty
Imatinib 250mg
$50.00
In stock
Imatinib 500mg
$80.00
In stock
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Adooq Products cited in reputable paper
Adooq's Imatinib (Gleevec) has been cited by 6 publications
  • Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
  • Takafumi Shima, .et al. , Oncol Rep, 2022, 47: 7 PMID: 34738628
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • BM Duggan, .et al. , Endocrinology, 2020, May 30;bqaa086 PMID: 32473019
  • Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961
  • Brittany M. Duggan, .et al. , Sci Rep, 2017, 7: 1578 PMID: 28484277
  • Biological Activity
    Discription Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.
    Targets
    Target Value
    Product Information
    Catalog Num A10259
    Formula C29H31N7O
    Molecular Weight 493.6
    CAS Number 152459-95-5
    SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
    Synonyms STI571, Glivec
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 28 mg/mL (56.72 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.26 mL 101.3 mL 202.59 mL
    0.5 mM 4.05 mL 20.26 mL 40.52 mL
    1 mM 2.03 mL 10.13 mL 20.26 mL
    5 mM 0.41 mL 2.03 mL 4.05 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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