Imatinib Mesylate

Catalog No.: A10468
Bcr-Abl inhibitor
Imatinib mesylate, a selective tyrosine kinase inhibitor, induced a sustained objective response in treating gastrointestinal stromal tumors with the inhibition of the KIT signal-transduction pathway.
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Product Name Price Stock Qty
Imatinib Mesylate 100mg
$60.00
In stock
Imatinib Mesylate 200mg
$70.00
In stock
Imatinib Mesylate 500mg
$80.00
In stock
Imatinib Mesylate 10mM * 1mL in DMSO
$50.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Imatinib Mesylate has been cited by 2 publications
  • Inge Govaerts, .et al. , J Hematol Oncol, 2021, 14: 97 PMID: 34167562
  • Genevra Kuziel, .et al. , Cancers (Basel), 2020, Jul 28;12(8):E2083 PMID: 32731354
  • Biological Activity
    Discription Imatinib mesylate, a selective tyrosine kinase inhibitor, induced a sustained objective response in treating gastrointestinal stromal tumors with the inhibition of the KIT signal-transduction pathway.
    Targets
    Target Value
    Product Information
    Catalog Num A10468
    Formula C29H31N7O.CH4SO3
    Molecular Weight 589.7
    CAS Number 220127-57-1
    SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
    Synonyms Gleevec, Glivec, CGP-57148B, STI-571
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 101 mg/mL (171.26 mM)
    Water 101 mg/mL (171.26 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 16.96 mL 84.79 mL 169.58 mL
    0.5 mM 3.39 mL 16.96 mL 33.92 mL
    1 mM 1.7 mL 8.48 mL 16.96 mL
    5 mM 0.34 mL 1.7 mL 3.39 mL
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