Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
L-Proline-d3 is a deuterium-labeled derivative of L-Proline, an essential amino acid integral to protein synthesis in living organisms. This stable isotope serves as a valuable tool in biochemical research, particularly in studies involving metabolic pathways, protein folding, and structure-function relationships of proteins. Its unique labeling facilitates advanced analytical techniques, including NMR and mass spectrometry, enabling precise tracking of metabolic processes and biomolecular interactions. -
Stable Isotope
Benzyl alcohol-d1 is a deuterium-labeled derivative of benzyl alcohol, serving as a stable isotope. It is primarily utilized in research applications such as mass spectrometry and metabolic studies, enabling the tracing of biological pathways and the quantitation of metabolites. Its distinct isotopic signature allows for enhanced specificity in chemical analysis and improved detection limits in various experimental setups. -
Stable Isotope
Fumaric acid-13C4 is a stable isotope-labeled form of fumaric acid, primarily utilized in metabolic studies and tracer experiments. Fumaric acid is recognized as an oncometabolite, implicated in fumarase deficiency and various cancer-related processes. The incorporation of the 13C label facilitates advanced research applications, including metabolic flux analysis and the investigation of biochemical pathways associated with cancer metabolism. -
Stable Isotope
3-Indoleacetic acid-d7 is a deuterium-labeled derivative of 3-Indoleacetic acid, a pivotal auxin and plant growth hormone. This stable isotope is employed in various research applications, particularly in studies investigating the mechanisms of plant growth and development. By incorporating 3-Indoleacetic acid-d7 into cell culture mediums, researchers can effectively explore the dynamics of cell elongation and division in plant systems. -
Stable Isotope
Glycolic acid-d2 is a deuterium-labeled variant of glycolic acid, functioning as a stable isotope. It acts as a selective inhibitor of tyrosinase, effectively suppressing melanin production, which can lead to skin lightening effects. This reagent is valuable for studies in skin biology, cosmetic research, and investigations into pigmentation processes. -
Stable Isotope
Glycerol-13C3 is a stable isotope-labeled form of glycerol, featuring three carbon-13 atoms. It serves as a valuable tool in sample preparation and is commonly employed in polyacrylamide gel electrophoresis to enhance the sensitivity of detection methods. The incorporation of Glycerol-13C3 allows for precise quantification and tracking of metabolic pathways in various biological studies. -
Stable Isotope
Hypoxanthine-d4 is a deuterium-labeled derivative of hypoxanthine, which serves as a stable isotope. It exhibits potential as a free radical generator and can be utilized as an indicator of hypoxic conditions. This compound is suitable for research applications focused on metabolism, hypoxia-related studies, and oxidative stress investigations, providing a valuable tool for analyzing purine metabolism and its implications in various biological processes. -
Stable Isotope
Cholesterol-13C2 is a stable isotope-labeled form of cholesterol, a critical sterol in mammalian biology. It constitutes 20-25% of the plasma membrane's structural components and is essential for regulating the fluidity and permeability of the membrane, influencing the behavior of transporters and signaling proteins. This compound also acts as an endogenous agonist for estrogen-related receptor α (ERRα), making it valuable for studies in cell membrane dynamics and receptor signaling in various biological contexts. -
Stable Isotope
3,4-Dihydroxybenzeneacetic acid-d5 is a deuterated stable isotope of 3,4-Dihydroxybenzeneacetic acid, which serves as a primary neuronal metabolite of dopamine. This labeled compound is essential for studying dopamine metabolism and its related pathways in neurological research. It provides valuable insights into the dynamics of neurotransmitter activity and can be utilized in various analytical techniques, including mass spectrometry and nuclear magnetic resonance spectroscopy. -
Stable Isotope
L-Alanine-d3 is a stable isotope of the non-essential amino acid L-Alanine, distinguished by the presence of deuterium. This compound plays a vital role in metabolic processes, particularly in sugar and acid metabolism. L-Alanine-d3 is utilized in various research applications, including studies of metabolic pathways, amino acid transport, and the tracing of metabolic processes in biological systems. Its incorporation into research provides enhanced analytical accuracy in understanding amino acid dynamics and energy production in tissues. -
Stable Isotope
Indole-d7 is a deuterium-labeled derivative of indole, serving as a stable isotope in chemical research. As an endogenous metabolite, indole plays a crucial role in various biological processes, including neurotransmitter synthesis and tryptophan metabolism. Indole-d7 is primarily utilized in mass spectrometry and other analytical techniques for metabolic tracing and studying metabolic pathways. Its isotopic labeling aids in quantifying concentrations and analyzing the kinetics of indole-related biological effects. -
Stable Isotope
p-Cresol sulfate-d7 potassium is a deuterium-labeled derivative of p-Cresyl sulfate, a known protein-bound uremic toxin. This stable isotope is utilized in metabolic studies and pharmacokinetic research to trace the behavior of p-Cresyl sulfate in biological systems. Its incorporation into research enables enhanced understanding of protein binding and uremic toxicity in clinical settings. -
Stable Isotope
Taurocholic acid-d4 sodium is a deuterium-labeled derivative of taurocholic acid, a bile acid primarily involved in the emulsification of dietary fats. This stable isotope is valuable for research applications, particularly in metabolic studies and tracer experiments that investigate lipid digestion and absorption. It can be utilized in mass spectrometry and other analytical techniques to trace metabolic pathways and quantify bile acid levels in biological samples. -
Stable Isotope
p-Coumaric acid-d6 is a deuterium-labeled derivative of p-Coumaric acid, a prominent isomer of cinnamic acid. This compound exhibits notable antitumor and anti-mutagenic properties, making it valuable for cancer research and mutagenesis studies. Its stable isotope labeling facilitates quantitative analysis and metabolic tracking in biochemical research applications. -
Stable Isotope
L-Threonine-13C4 is a stable isotope-labeled form of the amino acid L-Threonine. As a naturally occurring amino acid, L-Threonine plays a critical role in protein synthesis and is utilized widely in biochemical research. This stable isotope can be employed in metabolic studies, tracer experiments, and quantitative analyses to track metabolic pathways and protein dynamics in various biological systems. -
Stable Isotope
L-Tryptophan-d8 is a deuterium-labeled form of the essential amino acid L-Tryptophan, serving as a stable isotope for various research applications. It is a precursor to important biomolecules such as serotonin, melatonin, and vitamin B3. This reagent is valuable in metabolic studies, isotopic labeling experiments, and investigations of amino acid metabolism, aiding in the understanding of biological processes and drug development. -
Stable Isotope
L-Serine-d3 is a deuterium-labeled form of the non-essential amino acid L-Serine, which plays a crucial role in cellular proliferation and metabolic processes. This stable isotope is useful in research applications involving metabolic tracing and NMR spectroscopy. L-Serine-d3 allows for enhanced detection and quantification in various biochemical studies, thereby aiding in the understanding of amino acid metabolism and related pathways. -
Stable Isotope
i-Inositol-d6 is a deuterium-labeled form of i-Inositol, a naturally occurring compound involved in various biological processes. It serves as an important precursor for inositol phosphates and plays a critical role in cell signaling and membrane formation. This stable isotope is widely used in metabolic studies and tracer experiments to investigate cellular pathways and lipid metabolism. -
Stable Isotope
Estradiol-d5 is a deuterium-labeled derivative of estradiol, a steroid sex hormone essential for female fertility and the development of secondary sexual characteristics. This stable isotope serves as a valuable tool in research applications, particularly in metabolic studies and hormone tracking. Estradiol-d5 activates the estrogen receptor β (ERβ) pathway, leading to the upregulation of IL-6 expression, making it useful for investigating estrogen-related biological processes. -
Stable Isotope
Glutaric acid-d6 is a stable isotope-labeled form of glutaric acid, an important intermediate in the catabolic pathways of lysine and tryptophan. It plays a significant role in modulating pericyte contractility and migration, making it relevant for studies in cellular dynamics and pathology. Additionally, glutaric acid is an important biomarker for diagnosing glutaric aciduria type I, facilitating research in metabolic disorders. -
Stable Isotope
1-Methyl-L-histidine-d3 is a deuterium-labeled form of 1-Methyl-L-histidine, utilized as a stable isotope in metabolic studies. This compound serves as a valuable biomarker for quantifying meat consumption and the intake of exogenous 3-methylhistidine (3MH). Researchers can apply this reagent in dietary assessments and metabolic tracing to better understand protein turnover and the physiological effects of meat-derived amino acids. -
Stable Isotope
Hippuric acid-d2 is the deuterium-labeled form of hippuric acid, a stable isotope used in various analytical applications. As a metabolite of aromatic compounds, it plays a key role in studies involving metabolic pathways and biochemistry. Its incorporation in research can enhance the accuracy of metabolic profiling and pharmacokinetic studies, providing insights into the metabolism of aromatic substances in biological systems. -
Stable Isotope
L-Citrulline-d4 is the deuterium-labeled analog of the amino acid L-Citrulline, which plays a critical role in the urea cycle and the production of nitric oxide. This stable isotope is utilized in metabolic studies and pharmacokinetic research to trace metabolic pathways involving citrulline. Its applications include investigating amino acid metabolism and exploring nitric oxide-mediated physiological processes. -
Stable Isotope
L-Serine-13C is a stable isotope-labeled form of L-Serine, an amino acid fundamental to various biological processes. It plays a critical role in cellular proliferation and is involved in the synthesis of proteins and neurotransmitters. This reagent is particularly useful for metabolic studies, isotopic tracing experiments, and research related to amino acid metabolism. -
Stable Isotope
DEHP-d4 is a deuterated form of bis(2-ethylhexyl) phthalate (DEHP), serving as a stable isotope. This compound is utilized in biological studies to trace and quantify metabolic pathways involving DEHP, an endogenous metabolite. Its incorporation into research allows for enhanced accuracy in the analysis of phthalate exposure and its effects on biological systems. -
Stable Isotope
p-Tyramine-d4 hydrochloride is a deuterium-labeled variant of tyramine hydrochloride, which serves as a stable isotope for analytical applications. This compound is involved in the regulation of blood pressure and is naturally occurring in various foods and biological systems. It can be utilized in metabolic studies and tracing experiments to elucidate the role of tyramine in physiological processes. -
Stable Isotope
L-Aspartic acid-15N is a stable isotope-labeled form of the amino acid L-Aspartic acid. This compound plays a crucial role in various metabolic processes and is known for its ability to penetrate the blood-brain barrier. L-Aspartic acid-15N is primarily applied in the development of prodrugs targeting colon and cecal tissues and is also utilized in research related to inflammatory conditions. Its isotopic labeling allows for advanced studies in metabolic tracking and related biochemical pathways. -
Stable Isotope
Cinnamic acid-d6 is a deuterium-labeled derivative of cinnamic acid, serving as a stable isotope for analytical studies. Cinnamic acid is recognized for its potential anti-cancer properties, exhibiting IC50 values between 1-4.5 mM in various cancer cell lines, including glioblastoma, melanoma, prostate, and lung carcinoma. This compound is valuable for research applications that require tracking metabolic pathways, studying drug interactions, and understanding the mechanisms of action in cancer biology. -
Stable Isotope
L-Serine-d7 is a deuterated form of the non-essential amino acid L-Serine, serving as a stable isotope labeled compound. L-Serine is vital for cellular processes, including proliferation and metabolism. This reagent is primarily utilized in metabolic studies, tracer experiments, and proteomic analyses, enhancing the understanding of amino acid metabolism and biological pathways. -
Stable Isotope
L-Cysteine-13C3 is a stable isotope-labeled form of the conditionally essential amino acid L-Cysteine. This compound serves as a crucial precursor for biologically active molecules, including hydrogen sulfide (H2S), glutathione, and taurine, which are integral to various metabolic pathways. L-Cysteine is also noted for its role in appetite regulation, as it has been shown to suppress ghrelin levels in both rodent models and human studies. This reagent is valuable for metabolic studies and investigations into amino acid metabolism. -
Stable Isotope
L-Isoleucine-13C6 is a stable isotope-labeled form of the essential amino acid L-Isoleucine, which exhibits hydrophobic properties. As a nonpolar amino acid, L-Isoleucine plays a critical role in protein synthesis and energy production. This reagent is primarily utilized in metabolic studies, isotopic labeling experiments, and protein tracking to elucidate metabolic pathways and cellular processes. -
Stable Isotope
L-Ornithine-1,2,3,4,5-13C5 hydrochloride is a stable isotope-labeled form of the amino acid L-Ornithine. This compound is integral to the urea cycle, facilitating the excretion of excess nitrogen in the body. Its unique isotopic labeling makes it a valuable tool for metabolic studies and tracer experiments in biochemical research. -
Stable Isotope
L-Citrulline-d7 is a stable isotope-labeled form of L-Citrulline, an amino acid involved in various metabolic processes. It plays a critical role in the conversion of arginine to nitric oxide, impacting vasodilation and blood flow regulation. L-Citrulline-d7 is utilized in research applications such as metabolic studies, tracer kinetics, and pharmacokinetic investigations to provide insights into amino acid metabolism and related physiological functions. -
Stable Isotope
TRIA-662-d3 is a deuterium-labeled analog of TRIA-662, also known as 1-Methylnicotinamide chloride, which serves as an endogenous metabolite. This compound demonstrates significant antithrombotic and anti-inflammatory properties, making it a valuable tool for research in cardiovascular and inflammatory conditions. TRIA-662-d3 can be utilized in studies exploring metabolic pathways and for profiling biological activities in various assays. -
Stable Isotope
L-Pyroglutamic acid-d5 is a deuterium-labeled derivative of L-Pyroglutamic acid, which serves as a stable isotope for various research applications. The levo-isomer of pyroglutamic acid is biologically active in humans and plays a significant role as an intermediate in glutathione metabolism. This compound is useful in studies involving metabolic pathways, isotopic labeling, and tracer experiments in biochemical research. -
Stable Isotope
Stearic acid-d35 is a deuterium-labeled derivative of stearic acid, a long-chain saturated fatty acid commonly found in both animal and vegetable fats and oils. This stable isotope serves as a valuable tracer in metabolic studies and various biochemical assays, enabling researchers to investigate lipid metabolism and fatty acid incorporation. Applications include studying lipid profiles, dietary impacts, and metabolic pathways in diverse biological systems. -
Stable Isotope
Indole-3-acetamide-d5 is a deuterium-labeled derivative of Indole-3-acetamide, serving as a stable isotope for research applications. As an intermediate in the biosynthesis of indole-3-acetic acid, it plays a critical role in the synthesis of this essential plant growth hormone classified under auxins. This compound is valuable for studies investigating hormone biosynthesis, metabolic pathways, and plant growth regulation. -
Stable Isotope
Cholesterol-d6 is a deuterium-labeled form of cholesterol, a key sterol that constitutes 20-25% of the structural components of mammalian plasma membranes. It significantly influences membrane fluidity and permeability while modulating the activity of transporters and signaling proteins. In addition to its structural roles, cholesterol acts as an endogenous agonist for estrogen-related receptor α (ERRα), making Cholesterol-d6 valuable for studies in membrane biology and receptor interactions. Its stable isotope labeling aids in quantitative analyses of cholesterol dynamics in various biological systems. -
Stable Isotope
L-Serine-13C3,15N is a stable isotope-labeled form of L-Serine, incorporating three carbon-13 and one nitrogen-15 atoms. As a key non-essential amino acid, L-Serine is vital for various biological processes, including cellular proliferation and metabolism. This reagent is widely used in studies involving metabolic tracing, isotope labeling experiments, and amino acid metabolism research. -
Stable Isotope
N-Acetylglycine-d5 is a deuterium-labeled derivative of N-Acetylglycine, a naturally occurring compound found in various food sources. As a stable isotope, it serves as a valuable internal standard for analytical chemistry, particularly in mass spectrometry applications. Its unique labeling allows for precise quantification and tracing of metabolic pathways, making it useful in nutritional studies and flavor enhancement research. -
Stable Isotope
Glycocholic acid-d4 is a deuterium-labeled form of Glycocholic acid, a bile acid known for its anticancer properties. It primarily targets both pump resistance-related and non-pump resistance-related pathways, making it a valuable tool in cancer research. The stable isotope labeling enables precise tracking and quantification in biological studies, supporting investigations into the mechanisms of bile acids in cancer and drug resistance. -
Stable Isotope
Urea-15N2 is a stable isotope-labeled form of urea, incorporating nitrogen-15. This compound serves as a potent protein denaturant through both direct and indirect mechanisms, facilitating various biochemical studies. Its applications extend to evaluating renal function via blood urea nitrogen (BUN) measurements, as well as serving as a diuretic agent. Additionally, Urea-15N2 finds utility in agricultural research and the chemical industry as a nitrogen source for fertilizers and other products. -
Stable Isotope
Ethylene glycol-d4 is a deuterium-labeled form of ethylene glycol, serving as a stable isotope for various analytical applications. It is primarily utilized in NMR (nuclear magnetic resonance) spectroscopy to provide insight into molecular structure and dynamics. This compound is valuable in metabolomics studies, enabling researchers to trace metabolic pathways and interactions in biological systems. -
Stable Isotope
Allantoin-13C2,15N4 is a stable isotope-labeled derivative of Allantoin, featuring isotopic labeling at carbon and nitrogen positions. Allantoin functions as a skin conditioning agent, promoting healthy skin and stimulating the growth of new and healthy tissues. This compound is valuable for research applications in dermatological studies and metabolic labeling experiments. -
Stable Isotope
2-Methylcitric acid-d3 is a deuterium-labeled derivative of 2-Methylcitric acid, which functions as a stable isotope useful in metabolic studies. This compound is a key metabolite in the 2-methylcitric acid cycle, accumulating in conditions such as methylmalonic and propionic acidemias, thereby serving as a valuable biomarker. Additionally, 2-Methylcitric acid is known to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, making it relevant for research on mitochondrial function and metabolic disorders. -
Stable Isotope
Heptadecanoic acid-d33 is a deuterated form of heptadecanoic acid, an odd-chain saturated fatty acid (OCS-FA). This stable isotope is utilized in metabolic studies to investigate fatty acid metabolism and its implications in various diseases, including coronary heart disease, prediabetes, and type 2 diabetes, as well as multiple sclerosis. Its specific labeling allows for enhanced tracking and analysis in biochemical research and clinical studies focused on lipid profiles and disease associations. -
Stable Isotope
L-Isoleucine-15N is the stable isotope-labeled form of the essential amino acid L-Isoleucine. As a nonpolar hydrophobic amino acid, it plays a critical role in protein synthesis and metabolism. This reagent is particularly valuable in tracer studies and metabolic research, allowing for the precise tracking of amino acid metabolism and incorporation into proteins in various biological systems. -
Stable Isotope
L-Tryptophan-13C is a stable isotope-labeled form of the essential amino acid L-Tryptophan. Serving as a precursor to important biomolecules such as serotonin, melatonin, and vitamin B3, L-Tryptophan-13C is utilized in metabolic studies, tracer experiments, and other research applications that require isotopic labeling to track biochemical pathways and mechanisms in living systems. -
Stable Isotope
3-Hydroxyglutaric acid-d5 is a deuterated form of 3-Hydroxyglutaric acid, making it a stable isotope reagent. This compound serves as a valuable tool for metabolic studies and isotopic tracing in biochemical research. Its unique labeling allows for enhanced sensitivity in detection methods such as mass spectrometry, facilitating investigations into metabolic pathways and disorders associated with glutaric acid metabolism. -
Stable Isotope
L-Proline-d7 is a deuterated form of the amino acid L-Proline, functioning as a stable isotope tracer. It is utilized in metabolic studies and isotopic labeling experiments, enhancing the understanding of protein synthesis and metabolism. This compound is instrumental in various biological applications, including NMR spectroscopy and mass spectrometry, to track metabolic pathways and protein interactions in living organisms.
