Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Estriol-d is a deuterium-labeled form of Estriol, serving as a stable isotope for analytical applications. This compound acts as an antagonist of G-protein coupled estrogen receptors, particularly in estrogen receptor-negative breast cancer cells. It is valuable for studying estrogen receptor signaling and the effects of hormonal modulation in cancer research. -
Stable Isotope
Trihydroxycholestanoic acid-d3 is a deuterium-labeled derivative of Trihydroxycholestanoic acid, utilized as a stable isotope for advanced biochemical studies. This compound serves as a valuable tool for tracing metabolic pathways and enhancing mass spectrometry analysis in lipid research. Its incorporation allows for precise quantitation of cholestanol metabolism and related lipid interactions, making it essential for elucidating biosynthetic pathways and disease mechanisms. -
Stable Isotope
7β-Hydroxy-4-cholesten-3-one-d7 is a stable isotope-labeled derivative of 7β-Hydroxy-4-cholesten-3-one. This compound is primarily utilized in metabolic studies and tracer experiments, aiding in the understanding of cholesterol metabolism and related pathways. Its deuterated form enhances detection sensitivity in mass spectrometry applications, making it valuable for quantitative analysis in biochemical research. -
Stable Isotope
Ternidazole-d6 hydrochloride is a deuterated analog of Ternidazole hydrochloride, a nitroimidazole derivative known for its antiprotozoal activity. This stable isotope is useful in pharmacokinetic studies, enabling precise tracking of drug metabolism and distribution in biological systems. Its application extends to research involving the investigation of drug interactions and effectiveness against protozoan infections. -
Stable Isotope
Phenyl acetate-d5 is a deuterium-labeled analog of phenyl acetate, serving as a stable isotope for analytical applications. This compound functions as an endogenous metabolite and is associated with the metabolism of glutamine. Additionally, phenyl acetate-d5 may be employed as a biomarker for specific conditions, including depression, making it valuable for research in metabolic studies and disease detection. -
Stable Isotope
1,7-Dimethyluric acid-d3 is a deuterium-labeled derivative of 1,7-Dimethyluric acid, a known metabolite of caffeine. As a stable isotope, it serves as a valuable internal standard in analytical chemistry, particularly in studies involving caffeine metabolism and pharmacokinetics. This reagent is essential for enhancing the accuracy and precision of mass spectrometry and NMR experiments in metabolic research. -
Stable Isotope
4-Methyl-2-oxopentanoic acid-d7 sodium is a deuterated derivative of 4-Methyl-2-oxopentanoic acid, a key metabolite of L-leucine. This stable isotope is instrumental in studying energy metabolism, as it influences endoplasmic reticulum stress and lipid accumulation in preadipocytes. Additionally, 4-Methyl-2-oxopentanoic acid-d7 sodium has been shown to impair mTOR and autophagy signaling pathways, making it valuable for research into insulin resistance and metabolic disorders. -
Stable Isotope
Hydroxy ipronidazole-d3 is a deuterated form of Hydroxy ipronidazole, a metabolite of nitroimidazole antibiotics, including ipronidazole. This stable isotope can be utilized in pharmacokinetic studies to trace metabolic pathways and assess the mutagenic potential of related compounds. Research applications may involve investigations into the pharmacodynamics and safety profiles of nitroimidazole derivatives. -
Stable Isotope
L-Citrulline-d6 is a deuterium-labeled form of the amino acid L-citrulline, which plays a critical role in the urea cycle and nitrogen metabolism. It is produced from ornithine during the catabolism of proline, glutamine, or glutamate, as well as from l-arginine via the arginine-citrulline pathway. This stable isotope is utilized in metabolic studies, tracer experiments, and to track metabolic processes involving L-citrulline. It is valuable for research in biochemical and physiological studies related to nitric oxide synthesis and vascular health. -
Stable Isotope
Decanedioic acid-d4 is a deuterium-labeled derivative of decanedioic acid, a straight-chain dicarboxylic acid. This compound has been shown to effectively address metabolic inflexibility in type 2 diabetes and is implicated in the prevention and reversal of metabolic-associated liver disease and obesity. Additionally, decanedioic acid is relevant in studying carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency, making it a valuable tool for research in metabolic disorders. -
Stable Isotope
Allotetrahydrocortisol-d5 is a deuterium-labeled analog of allotetrahydrocortisol, a metabolite of cortisol. As the primary glucocorticoid in humans, cortisol is synthesized in the adrenal cortex and is essential in regulating various physiological processes, including metabolism, immune response, and stress adaptation. Allotetrahydrocortisol-d5 serves as a stable isotope standard for quantitative analysis in metabolic studies and pharmacokinetic research, enabling researchers to accurately trace cortisol metabolism and its biological effects. -
Stable Isotope
p-Toluic acid-d4 is a deuterium-labeled derivative of p-Toluic acid, a substituted benzoic acid. This stable isotope serves as an important intermediate in the synthesis of various compounds, including para-aminomethylbenzoic acid (PAMBA) and p-tolunitrile. Its applications extend to studies involving metabolic pathways and the characterization of reaction mechanisms in chemical research. -
Stable Isotope
Vanillylmandelic acid-d is a deuterated form of Vanillylmandelic acid, a stable isotope commonly utilized in metabolic studies. As a key metabolite of epinephrine and norepinephrine, it serves as a biomarker for disruptions in neurotransmitter metabolism. Additionally, Vanillylmandelic acid exhibits antioxidant properties, effectively scavenging DPPH radicals with an IC50 of 33 μM, making it valuable for research involving oxidative stress and neuronal health. -
Stable Isotope
L-Leucine-d is the deuterium-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) that activates the mTOR signaling pathway. This stable isotope enables the study of metabolic processes and protein synthesis, providing insights into cellular function and regulatory mechanisms. L-Leucine-d is valuable for research applications in nutrition, metabolism, and muscle physiology. -
Stable Isotope
4-O-Methyldopa-d3 is a deuterium-labeled analog of 4-O-Methyldopamine. This stable isotope is utilized primarily in pharmacokinetic studies and metabolic research to trace the dynamics of neurochemical processes. Its applications include the investigation of dopaminergic signaling pathways and the study of drug metabolism and disposition. -
Stable Isotope
5-Methyluridine-5′-13C is a stable isotope-labeled form of 5-Methyluridine, which is an endogenous methylated nucleoside commonly found in human biology. This reagent serves as a valuable tool for metabolic studies and tracer experiments, enabling researchers to track nucleoside metabolism and its effects in various biological systems. It is particularly useful in investigating RNA methylation mechanisms and studying the role of nucleosides in cellular processes. -
Stable Isotope
Vitamin K1-d3 (Phylloquinone-d3; Phytomenadione-d3) is a deuterium-labeled variant of Vitamin K1. This stable isotope is utilized in metabolic studies and tracer experiments to investigate Vitamin K1 dynamics in biological systems. Its isotopic labeling allows for precise quantification and tracking of Vitamin K metabolism, thus aiding research on its physiological roles and potential therapeutic applications. -
Stable Isotope
(R)-Pyrrolidine-2-carboxylic acid-d3 is a deuterium-labeled form of (R)-pyrrolidine-2-carboxylic acid, an important endogenous metabolite. This stable isotope is utilized in metabolic studies and tracer experiments, providing insights into biochemical pathways. Its accurate labeling enhances the detection and quantification of metabolites in various biological samples, facilitating research in metabolism and related fields. -
Stable Isotope
D-Ribose-18O is a stable isotope-labeled form of D-Ribose, a critical sugar moiety in adenosine triphosphate (ATP) synthesis. This compound serves as an energy enhancer and is utilized in metabolic therapy, particularly for conditions like chronic fatigue syndrome and cardiac energy metabolism. Additionally, D-Ribose plays a role in protein glycation studies, making it valuable for research in metabolic pathways and energy regulation. -
Stable Isotope
3-Hydroxybutyric acid-d2 sodium is a stable isotope-labeled derivative of 3-Hydroxybutyric acid sodium, a key metabolite associated with type I diabetes. This compound exhibits noteworthy effects on membrane lipid properties, making it a valuable tool for studying metabolic pathways and lipid interactions. Its use in research facilitates the investigation of metabolic disorders and the role of ketone bodies in energy metabolism. -
Stable Isotope
2'-Deoxyuridine-5′-13C is a stable isotope-labeled form of 2'-Deoxyuridine. This compound is known to enhance chromosome breakage and reduce thymidylate synthase activity, making it a valuable tool for studying DNA synthesis and repair mechanisms. Its applications extend to the synthesis of nucleoside analogs such as Edoxudine, facilitating research in cancer and antiviral therapies. -
Stable Isotope
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is a deuterium-labeled derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE), a phosphoethanolamine (PE) lipid. This stable isotope is utilized in biochemical research to track lipid metabolism and dynamics within biological systems. Its applications include the formulation of liposomes and nanoparticles for drug delivery, as well as the study of membrane protein interactions and lipid signaling pathways. -
Stable Isotope
Vitamin K1-d4 is a deuterated form of Vitamin K1, serving as a stable isotope. This compound is essential for various biological processes, including blood coagulation and the metabolism of bone and vascular tissues. It is widely used in research applications involving metabolic tracing and the study of vitamin K dynamics in biological systems. -
Stable Isotope
D-Glycerol-13C-3 is a stable isotope-labeled form of D-Glycerol, featuring three carbon-13 isotopes. This compound is utilized in metabolic studies and tracer experiments, enabling the examination of glycerol metabolism and its incorporation into various biochemical pathways. It serves as a valuable tool for researchers investigating metabolic flux analysis and isotopic labeling in cellular studies. -
Stable Isotope
L-Alanine-2-13C is a stable isotope-labeled form of L-Alanine, a non-essential amino acid crucial for various metabolic processes, including glucose metabolism and nitrogen balance. It plays a significant role in energy production for muscle tissue and the central nervous system, as well as in enhancing immune function. This reagent is valuable for research applications in metabolic studies, tracer experiments, and protein synthesis investigations. -
Stable Isotope
Thyminose-13C-1 is a stable isotope-labeled version of thyminose, an endogenous metabolite involved in various biochemical pathways. This compound is utilized in metabolic studies and isotope labeling experiments, providing insights into metabolic processes and cellular functions. The incorporation of 13C allows for enhanced tracking and quantification in biological systems, facilitating advanced research in metabolic flux analysis and related areas. -
Stable Isotope
Bisphenol A-d4-1 is a deuterated analog of Bisphenol A, primarily utilized as a stable isotope for tracing and analytical applications. This compound is significant in research due to its role as an endocrine-disrupting chemical, associated with various health implications such as reproductive and developmental toxicities. It is commonly employed in studies investigating the effects of environmental contaminants on human health and disease, particularly within the fields of toxicology and endocrine research. -
Stable Isotope
D-Galactose-d-1 is a deuterium-labeled derivative of D-Galactose, a naturally occurring aldohexose and C-4 epimer of glucose. This stable isotope is widely utilized in metabolic studies, particularly in tracer experiments for glycan analysis and carbohydrate metabolism. Its incorporation into various biological systems enhances the understanding of metabolic pathways and the role of sugars in cellular processes. -
Stable Isotope
2'-Deoxyuridine-3′-13C is a stable isotope-labeled analog of 2'-Deoxyuridine, featuring a carbon-13 isotope at the 3' position. This compound can lead to increased chromosome breakage and a reduction in thymidylate synthetase activity, making it a valuable tool in studies of nucleic acid metabolism and repair mechanisms. It is also utilized as a precursor in the synthesis of various pharmaceuticals, including Edoxudine, enhancing its applicability in biochemical research. -
Stable Isotope
L-(-)-Sorbose-13C-2 is a stable isotope-labeled form of (3S,4R,5S)-1,3,4,5,6-pentahydroxyhexan-2-one, which serves as an endogenous metabolite. The incorporation of the 13C label allows for precise tracking in metabolic studies and bioanalytical applications. This reagent is valuable for researchers investigating carbohydrate metabolism, metabolic pathways, and kinetics of enzymatic reactions involving sorbose derivatives. -
Stable Isotope
Cholesterol-18O is a stable isotope-labeled form of cholesterol, a crucial sterol in mammalian biology. It constitutes approximately 20-25% of the plasma membrane's structural components, influencing membrane fluidity and permeability. This compound is vital for studies on membrane dynamics, neuronal signaling, and transport protein function, as well as for investigating cholesterol's role as an endogenous agonist of estrogen-related receptor α (ERRα). Cholesterol-18O serves as a valuable tool for tracing metabolic pathways and examining lipid dynamics in various biological systems. -
Stable Isotope
L-Aspartic acid-15N,d3 is a stable isotope-labeled form of L-Aspartic acid, incorporating deuterium and nitrogen-15. This amino acid is known for its ability to penetrate the blood-brain barrier and is frequently employed in the development of prodrugs targeting colon and cecal tissues. Additionally, L-Aspartic acid is utilized in research on inflammatory conditions, providing insights into metabolic pathways and cellular responses in various biological contexts. -
Stable Isotope
4-Methoxybenzaldehyde-d1 is a deuterium-labeled analogue of 4-Methoxybenzaldehyde, a naturally occurring aromatic compound known for its distinct fragrance. This reagent is utilized in stable isotope labeling studies to elucidate the metabolic pathways and biological interactions of phenolic compounds. Research applications include investigations into its potential neurotoxic effects, including mortality and behavioral responses in various organisms, making it valuable for studies in environmental toxicology and plant chemistry. -
Stable Isotope
7-Hydroxy coumarin sulfate-d5 potassium is a deuterated stable isotope of 7-Hydroxy coumarin sulfate potassium, which serves as a metabolite of 7-Ethoxycoumarin. This compound is utilized in various research applications, including metabolic studies and tracing mechanisms of drug metabolism. Its stable isotope labeling facilitates accurate quantification and identification in biological samples, proving essential for understanding biochemical pathways and pharmacokinetics. -
Stable Isotope
D-Ribose-d-3 is a deuterium-labeled form of D-Ribose, primarily utilized as a stable isotope in biochemical research. It serves as a critical sugar moiety of adenosine triphosphate (ATP), playing a significant role in cellular energy metabolism. D-Ribose-d-3 is frequently used in studies focusing on metabolic therapies, particularly for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Its incorporation in research aids in understanding metabolic pathways and energy production at the molecular level. -
Stable Isotope
Cholestenone-d7 is a deuterium-labeled variant of Cholestenone (4-Cholesten-3-one), which serves as a stable isotope for research applications. It is primarily involved in the metabolic pathways of cholesterol, particularly in the liver. Due to its high mobility within membrane systems, Cholestenone-d7 plays a significant role in studies of cholesterol dynamics and membrane transport mechanisms. This reagent is essential for understanding cholesterol metabolism and developing related therapeutic approaches. -
Stable Isotope
(±)-1,2-Propanediol-d2 is a deuterium-labeled form of (±)-1,2-Propanediol, a versatile aliphatic alcohol. This stable isotope is commonly utilized as an excipient in various formulations to enhance solubility and stability of active compounds. Its incorporation in research allows for advanced studies in pharmacokinetics and metabolic processes. -
Stable Isotope
Xylose-d-3 is a deuterium-labeled form of xylose, a five-carbon sugar. This stable isotope is primarily used as a tracer in metabolic studies and glycoprotein synthesis investigations. Its incorporation into biological systems allows for the assessment of carbohydrate metabolism and the dynamics of glycan structures in various research applications. -
Stable Isotope
Carbamazepine 10,11-epoxide-13C,d2 is a deuterated stable isotope of the active metabolite Carbamazepine 10,11-epoxide. This compound plays a crucial role in understanding the pharmacokinetics of Carbamazepine, an established anticonvulsant agent used for the treatment of epilepsy. Its use in research enables precise tracking of the drug's metabolic pathways and assessing its therapeutic efficacy in seizure management. -
Stable Isotope
D-Sorbitol-d-2 is a deuterium-labeled form of D-Sorbitol, a six-carbon sugar alcohol utilized as a sugar substitute. This compound serves as a stabilizing excipient, isotonicity agent, sweetener, humectant, and thickener in various formulations. Its unique isotopic labeling allows for enhanced tracking in metabolic studies and other research applications involving carbohydrate metabolism. D-Sorbitol-d-2 is essential for studies utilizing stable isotope labeling techniques. -
Stable Isotope
3-Pyridylacetic acid-d4 hydrochloride is a deuterated derivative of 3-Pyridylacetic acid hydrochloride. This stable isotope is utilized in various research applications, particularly in studies involving the metabolic pathways of nicotine and other tobacco alkaloids. Its incorporation into experimental designs facilitates quantitative analysis and tracking of biological processes involving pyridine derivatives. -
Stable Isotope
1-Hydroxyoctadecane-d37 is a deuterated stable isotope of 1-Hydroxyoctadecane, an endogenous metabolite involved in various biological processes. This reagent serves as an essential tool for metabolic studies and quantitative analysis in biochemical research. Its isotopic labeling enables precise tracking and identification in complex biological systems, facilitating advancements in metabolomics and related fields. -
Stable Isotope
D-Mannose-d-3 is a deuterated form of D-Mannose, a pivotal carbohydrate involved in human metabolism. It participates in the glycosylation of specific proteins, impacting various biological processes. This stable isotope is valuable for metabolic studies and tracer experiments, providing insights into carbohydrate metabolism and related pathways. -
Stable Isotope
N1,N8-Diacetylspermidine-d6 is a deuterium-labeled analogue of N1,N8-Diacetylspermidine, serving as a stable isotope tracer in biochemical research. This compound is involved in polyamine metabolism and is found in human urine, making it a valuable biomarker in studies related to cancer. Its application as a prognostic indicator facilitates the monitoring of treatment responses and follow-up examinations in cancer patients. -
Stable Isotope
1-Hexadecanol-d4 is a deuterated form of 1-Hexadecanol, a fatty alcohol characterized by its lipophilic properties. This stable isotope is essential for metabolic studies, allowing for the tracing and quantification of lipid metabolism pathways in biological systems. It is widely used in research applications related to lipid biochemistry and fatty acid metabolism. -
Stable Isotope
N-Acetyl-D-glucosamine-13C3,15N is a stable isotope-labeled form of N-Acetyl-D-glucosamine, featuring three carbon-13 and one nitrogen-15 isotopes. As a derivative of glucosamine, it serves as a critical intermediate in the synthesis of glycosaminoglycans and is involved in various biological processes, including cell signaling and metabolism. This reagent is essential for studies in metabolic tracing, structural biology, and the investigation of glycan interactions in cellular systems. -
Stable Isotope
Stearic acid-9,10-d2 is a deuterium-labeled variant of stearic acid. As a long-chain saturated fatty acid, stearic acid is commonly found in various animal and vegetable fats and oils. This stable isotope is utilized in metabolic studies, tracing fatty acid metabolism, and understanding lipid dynamics in biological systems. Its unique labeling enables precise tracking of stearic acid and its derivatives in research applications. -
Stable Isotope
DPPC-d66 is a deuterium-labeled form of di-palmitoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This compound is primarily utilized in the preparation of liposomal monolayers, facilitating studies on lipid bilayer properties. DPPC-liposomes are effective delivery vehicles that enhance immune responses against glycosphingolipid (GSL) antigens, making them valuable in immunological research and drug delivery applications. -
Stable Isotope
Indole-13C8,15N is a stable isotope-labeled variant of indole, featuring both carbon-13 and nitrogen-15 isotopes. Indole, an endogenous metabolite, plays a crucial role in various biochemical processes, including tryptophan metabolism and neurotransmitter synthesis. This reagent is valuable for metabolic studies, isotopic tracer experiments, and elucidating metabolic pathways involving indole and its derivatives. -
Stable Isotope
Thyminose-13C-2 is a stable isotope variant of thyminose, an endogenous metabolite integral to nucleic acid synthesis. This compound serves as a valuable tracer in metabolic studies, allowing researchers to investigate metabolic pathways and nucleotide metabolism in biological systems. Its unique isotopic labeling enables precise tracking and quantification in various applications, including cellular metabolism and biochemistry research.
