Cholesterol-18O is a stable isotope-labeled form of cholesterol, a crucial sterol in mammalian biology. It constitutes approximately 20-25% of the plasma membrane's structural components, influencing membrane fluidity and permeability. This compound is vital for studies on membrane dynamics, neuronal signaling, and transport protein function, as well as for investigating cholesterol's role as an endogenous agonist of estrogen-related receptor α (ERRα). Cholesterol-18O serves as a valuable tool for tracing metabolic pathways and examining lipid dynamics in various biological systems.
Cholesterol-18O is a stable isotope-labeled form of cholesterol, a crucial sterol in mammalian biology. It constitutes approximately 20-25% of the plasma membrane's structural components, influencing membrane fluidity and permeability. This compound is vital for studies on membrane dynamics, neuronal signaling, and transport protein function, as well as for investigating cholesterol's role as an endogenous agonist of estrogen-related receptor α (ERRα). Cholesterol-18O serves as a valuable tool for tracing metabolic pathways and examining lipid dynamics in various biological systems.
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