Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
L-Alanine-d3-1 is a stable isotope-labeled form of the non-essential amino acid L-Alanine. This amino acid plays a crucial role in metabolic processes, particularly in sugar and acid metabolism, and is essential for energy production in muscle tissue and the central nervous system. L-Alanine-d3-1 is valuable for studies in metabolic research, isotope tracing, and providing insight into amino acid metabolism and immune response mechanisms. -
Stable Isotope
Cholesterol-13C5 is a stable isotope-labeled form of cholesterol, a primary sterol found in mammals that constitutes 20-25% of the plasma membrane's structural components. It plays a critical role in regulating membrane fluidity and permeability, influencing the functionality of transporters and signaling proteins. Additionally, cholesterol acts as an agonist for the estrogen-related receptor α (ERRα), making it valuable for research in cell membrane dynamics and receptor interaction studies. This reagent is essential for tracing studies and metabolic research involving cholesterol metabolism. -
Stable Isotope
Hypoxanthine-13C2,15N is a stable isotope-labeled purine derivative with both 13C and 15N isotopes. This compound serves as a potential generator of free radicals and can be utilized as a biomarker for hypoxia in various biological systems. It is particularly useful in metabolic studies and investigations involving hypoxic conditions, allowing researchers to trace metabolic pathways and understand cellular responses to low oxygen levels. -
Stable Isotope
3-Hydroxyanthranilic acid-d3 is a deuterium-labeled analog of 3-Hydroxyanthranilic acid, utilized as a stable isotope in research. This compound serves as a valuable tracer in metabolic studies and is instrumental in elucidating biochemical pathways involving tryptophan metabolism. Its stable isotope properties enable precise quantification in various analytical techniques, including mass spectrometry. -
Stable Isotope
D-Valine-d8 is a deuterated form of D-Valine, the enantiomer of L-Valine, which is one of the 20 standard amino acids used in protein synthesis. The incorporation of stable isotopes, such as deuterium, in D-Valine-d8 allows for advanced tracing applications in metabolic studies and quantitative analyses in mass spectrometry. This reagent is essential for research exploring amino acid metabolism, protein interaction dynamics, and for labeling studies in various biological systems. -
Stable Isotope
Thymine-d4-1 is a deuterated form of thymine, a nucleobase essential to DNA structure and function. This stable isotope is utilized in research applications that require isotopic labeling, including studies on nucleic acid metabolism and the effects of chemotherapeutic agents like 5-fluorouracil (5-FU), which targets thymine with a Km of 2.3 μM. Its incorporation into molecular studies can aid in elucidating biological pathways and drug mechanisms in cancer research. -
Stable Isotope
1-Palmitoyl-sn-glycero-3-phosphocholine-d31 is a deuterated stable isotope of 1-Palmitoyl-sn-glycero-3-phosphocholine, a prominent lysophosphatidylcholine with notable proinflammatory properties. This reagent is valuable for research applications focusing on lipid metabolism, cell signaling, and the pathophysiology of conditions such as atherosclerosis. The introduction of deuterium enables enhanced quantification and tracking of metabolic processes in various biological systems. -
Stable Isotope
(±)-1,2-Propanediol-d8 is a deuterium-labeled form of (±)-1,2-Propanediol, an aliphatic alcohol known for its role as a solvent and stabilizing agent in various formulations. This stable isotope is particularly valuable for enhancing the solubility and stability of other compounds in analytical and pharmacological studies. Its applications extend to tracer studies and metabolic pathway investigations, making it an essential reagent in chemical research and development. -
Stable Isotope
D-Ribose-13C is a stable isotope-labeled form of D-Ribose, crucial for metabolic studies. As a key component of adenosine triphosphate (ATP), D-Ribose plays a significant role in cellular energy production and is utilized in metabolic therapy for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Its incorporation into research enables the investigation of metabolic pathways and protein glycation processes. -
Stable Isotope
L-Serine-13C3,15N,d3 is a stable isotope-labeled form of L-Serine, featuring deuterium (d3), carbon-13 (13C3), and nitrogen-15 (15N) isotopes. This non-essential amino acid is crucial for numerous biological processes, including cellular proliferation and amino acid biosynthesis. It serves as a valuable tool in metabolic studies, stable isotope labeling experiments, and tracer studies to investigate metabolic pathways and protein synthesis. -
Stable Isotope
7-Dehydrocholesterol-d7 is a deuterium-labeled form of 7-dehydrocholesterol, a crucial biosynthetic precursor in the synthesis of cholesterol and vitamin D3. This stable isotope is utilized in metabolic studies and tracer experiments to investigate biochemical pathways involving cholesterol metabolism and vitamin D synthesis. Its deuterium labeling enables precise quantification and tracking in complex biological systems. -
Stable Isotope
Ethynyl Estradiol-13C2 is a stable carbon isotope-labeled form of Ethynyl Estradiol, featuring a terminal alkyne group. This compound serves as a valuable reagent for click chemistry applications, specifically facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing substrates. Its ability to act as a tracer in biological studies enables researchers to investigate metabolic pathways and interactions involving estrogenic activity. -
Stable Isotope
1-Hexadecanol-d5 is a deuterated form of 1-Hexadecanol, serving as a stable isotope for chemical research. As a fatty alcohol, it exhibits lipophilic properties, making it useful in various biological and biochemical studies. Its application in isotopic labeling enables researchers to track metabolic pathways and investigate lipid metabolism in cellular models. -
Stable Isotope
L-Proline-13C is a stable isotope-labeled form of L-Proline, an amino acid critical for protein synthesis in living organisms. The incorporation of carbon-13 enables tracing and metabolic studies, making it a valuable tool for research in protein dynamics and metabolic pathways. L-Proline-13C is useful in applications such as NMR spectroscopy and mass spectrometry to investigate biochemical processes and amino acid metabolism. -
Stable Isotope
L-Tyrosine-4-13C is a stable isotope-labeled form of L-Tyrosine, a non-essential amino acid involved in neurotransmitter synthesis. This compound serves as a valuable tracer in metabolic studies and isotopic labeling experiments. Additionally, L-Tyrosine-4-13C can be used to investigate its effects on metabolic pathways, such as the inhibition of citrate synthase activity in the posterior cortex. -
Stable Isotope
Glycerol-d5 is a deuterated form of glycerol, serving as a stable isotope used in various biochemical applications. It is frequently utilized in sample preparation and gel formation for polyacrylamide gel electrophoresis, providing enhanced resolution and accuracy in the analysis of biomolecules. Its incorporation into experimental protocols aids in tracking molecular pathways and studying metabolic processes. -
Stable Isotope
L-Leucine-2-13C,15N is a stable isotope-labeled form of the essential branched-chain amino acid L-Leucine. This compound primarily targets the mTOR signaling pathway, playing a critical role in protein synthesis and cell growth. It is valuable in metabolic studies, tracking amino acid utilization, and investigating metabolic disorders. L-Leucine-2-13C,15N is useful for researchers exploring the effects of amino acids on cellular processes in various biological contexts. -
Stable Isotope
D-Glucose-d4 is a deuterium-labeled form of D-Glucose, a fundamental monosaccharide involved in various biological processes. This stable isotope is essential for metabolic studies and tracer applications in research, facilitating the investigation of glucose metabolism and metabolic flux analysis. Its unique labeling enables precise tracking in biological systems, making it invaluable for biochemical and pharmacological studies. -
Stable Isotope
3-Indoleacetic acid-d4 is a deuterium-labeled derivative of 3-Indoleacetic acid, a potent plant growth hormone classified as an auxin. This stable isotope is utilized in research applications to study plant cell biology, as it promotes cell elongation and division when added to cell culture media. Its isotopic labeling allows for precise tracking and analysis in various experimental settings, enhancing the understanding of plant development and hormonal pathways. -
Stable Isotope
L-5-Hydroxytryptophan-d4 is a deuterated form of L-5-Hydroxytryptophan (L-5-HTP), which serves as a stable isotope for analytical applications. As the direct precursor to serotonin, L-5-HTP plays a crucial role in neurotransmitter synthesis and exhibits potential benefits in mood regulation, appetite control, and sleep enhancement. This compound is widely utilized in research to investigate its therapeutic effects in conditions such as fibromyalgia, myoclonus, migraines, and cerebellar ataxia. -
Stable Isotope
Menadione-d3 is a deuterium-labeled analogue of Menadione, a synthetic naphthoquinone precursor. This compound serves as a stable isotope, facilitating research into vitamin K metabolic pathways. Menadione can be bioactivated to form vitamin K2 in vivo, making Menadione-d3 valuable for studies on vitamin K's biological functions and its role in coagulation and bone metabolism. -
Stable Isotope
Bisphenol A-d14 is a deuterated form of Bisphenol A, serving as a stable isotope for research applications. This compound, a prominent phenolic synthetic derivative, is commonly implicated in the production of polycarbonate plastics and epoxy resins. As an endocrine-disrupting chemical, Bisphenol A-d14 can aid in the study of its reproductive, developmental, and systemic toxic effects, contributing to the understanding of its role in various diseases, including cardiovascular, respiratory, and metabolic disorders. -
Stable Isotope
Paraxanthine-13C4,15N3 is a stable isotope-labeled form of the caffeine metabolite, Paraxanthine, featuring four 13C and three 15N isotopes. This compound is recognized for its neuroprotective properties, particularly in safeguarding dopaminergic neurons from cell death by stimulating Ryanodine Receptor Channels. Paraxanthine-13C4,15N3 is valuable in biochemical research, metabolic studies, and tracing studies involving caffeine metabolism and pharmacology. -
Stable Isotope
Vitamin K1-d7 is a deuterium-labeled derivative of Vitamin K1, primarily utilized as a stable isotope in research applications. As a naturally occurring vitamin, Vitamin K1 is essential for blood coagulation as well as bone and vascular metabolism. The labeled form enables precise tracking and analysis in metabolic studies, enhancing understanding of Vitamin K's physiological roles and interactions in various biological processes. -
Stable Isotope
L-Hexanoylcarnitine-d3 chloride is a stable isotope-labeled form of L-Hexanoylcarnitine chloride, incorporating deuterium for enhanced tracking in metabolic studies. This reagent serves as a valuable tool in the investigation of carnitine metabolism and fatty acid oxidation pathways. Its application in research includes the study of mitochondrial function, lipid metabolism, and potential therapeutic targets in metabolic disorders. -
Stable Isotope
Isovaleric acid-d9 is a deuterated stable isotope of isovaleric acid. This natural fatty acid has been implicated in neonatal death and is associated with Jamaican vomiting sickness in humans. Isovaleric acid-d9 serves as a valuable tool in metabolic studies and pharmacokinetic research, enabling investigators to trace metabolic pathways and assess the effects of isovaleric acid in biological systems. -
Stable Isotope
Elaidic acid-d9 is a deuterium-labeled derivative of elaidic acid, primarily utilized as a stable isotope in research applications. Elaidic acid, the predominant trans fatty acid in hydrogenated vegetable oils, serves as a pharmaceutical solvent, aiding in the delivery and formulation of drug compounds. This stable isotope can be essential for tracer studies and metabolic research, providing insights into lipid metabolism and trans fat dynamics in biological systems. -
Stable Isotope
L-Tyrosine-1-13C is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine. This compound is utilized in metabolic studies and tracer experiments due to its ability to participate in various biosynthetic pathways. Additionally, L-Tyrosine-1-13C can inhibit citrate synthase activity in the posterior cortex, making it a valuable tool for investigating metabolic processes and neurobiological research. -
Stable Isotope
L-Methionine-1-13C is a stable isotope-labeled form of L-Methionine, the L-isomer of the essential amino acid Methionine. As a crucial component in protein synthesis, Methionine serves various roles in supporting cellular function, including acting as a hepatoprotectant. This reagent is valuable in metabolic studies and tracing experiments, facilitating insights into amino acid metabolism and its physiological implications. -
Stable Isotope
Arabinose-d is a deuterium-labeled form of arabinose, a naturally occurring pentose sugar involved in various biological processes. This stable isotope is utilized in metabolic studies and tracer experiments, enabling researchers to trace metabolic pathways and analyze carbohydrate metabolism with enhanced precision. Arabinose-d serves as an important tool in biochemical research aimed at understanding glycan structures and functions. -
Stable Isotope
L-Homoarginine-13C7,15N4 hydrochloride is a stable isotope-labeled analog of the endogenous metabolite H-HomoArg-OH.HCl. Incorporating 13C and 15N isotopes, this compound is useful in metabolic studies and biochemical research. Its stable isotopic profile enables precise tracking of metabolic processes and interactions in biological systems. -
Stable Isotope
Phenylglyoxylic acid-d5 is a deuterium-labeled analog of phenylglyoxylic acid, functioning primarily as a stable isotope. This compound serves as a biomarker for human exposure to ethylbenzene and styrene, making it valuable in environmental and toxicological research. Additionally, phenylglyoxylic acid-d5 can be utilized as an intermediate in the synthesis of antineoplastic agents, contributing to cancer research and drug development efforts. -
Stable Isotope
L-Serine1-13C,15N is a stable isotope-labeled form of L-Serine, incorporating both 13C and 15N isotopes. As a non-essential amino acid, L-Serine is crucial for various metabolic processes, including cellular proliferation and neurotransmitter synthesis. This labeled compound serves as a valuable tool in metabolic studies, providing insights into amino acid metabolism and the physiological roles of serine in biological systems. -
Stable Isotope
Methyl 2-(1H-indol-3-yl)acetate-d5 is the deuterated derivative of Methyl 2-(1H-indol-3-yl)acetate, a stable isotope used in biochemical research. As an endogenous metabolite, it plays a crucial role in metabolic pathways, enabling researchers to investigate these processes using mass spectrometry and NMR spectroscopy. This labeled compound is essential for studying synthesis, degradation, and the metabolism of indole derivatives in various biological systems. -
Stable Isotope
Dihomo-γ-linolenic acid-d6 is a deuterium-labeled analog of Dihomo-γ-linolenic acid (DGLA), a 20-carbon omega-6 fatty acid known for its anti-inflammatory and anti-proliferative properties. DGLA plays a significant role in lipid metabolism and is involved in cellular signaling pathways. This stable isotope is particularly useful in metabolic research and tracer studies, enabling precise tracking of fatty acid metabolism and its effects in various biological systems, including the investigation of atherosclerosis in model organisms. -
Stable Isotope
Leukotriene E4-d5 is a deuterium-labeled analog of Leukotriene E4, a potent inflammatory mediator produced by the enzymatic conversion of LTD4 through dipeptidase activity. It serves as a key constituent of slow-reacting substance of anaphylaxis (SRS-A) and is implicated in various inflammatory responses. This stable isotope is particularly useful in research applications for studying asthma and other respiratory conditions, as it allows for accurate measurement of Leukotriene E4 levels in biological samples, including plasma and urine. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-13C3 is a stable isotope-labeled variant of propane-1,2,3-triyl tripalmitate, an endogenous metabolite involved in lipid metabolism. The incorporation of the stable carbon-13 isotope allows for precise tracking and quantification in metabolic studies. This reagent is valuable for research applications focused on lipid profiling, metabolic pathways, and the dynamics of fatty acid metabolism. -
Stable Isotope
L-Alanine-1-13C is a stable isotope-labeled form of the non-essential amino acid L-Alanine. It plays a crucial role in metabolism, particularly in the synthesis and degradation of sugars and organic acids. This compound can be utilized in metabolic studies, tracer experiments, and analyses of metabolic pathways, aiding in the understanding of amino acid functions and energy provision in muscle, brain, and central nervous system tissues. -
Isotope-Labeled Compounds
(±) Anabasine-d4 is a deuterated analog of (±) Anabasine, serving as a useful isotope-labeled compound. This racemic mixture acts as an agonist of the α7 nicotinic acetylcholine receptor (α7nAChR), demonstrating notable anti-inflammatory properties and insecticidal activity. It is suitable for applications in pharmacological research, particularly studies involving receptor activation and inflammatory responses. -
Stable Isotope
Estriol-d2 is a deuterated form of estriol, serving as a stable isotope for research applications. It functions as an antagonist of G-protein coupled estrogen receptors, particularly in estrogen receptor-negative breast cancer cells. This compound is valuable for studying estrogen signaling pathways and developing therapeutic strategies in hormone-related cancers. Its isotopic labeling also enhances analytical techniques such as mass spectrometry for investigating biological processes. -
Stable Isotope
p-Coumaric acid-13C3 is a stable isotope-labeled form of p-Coumaric acid, an isomer of cinnamic acid. This compound exhibits notable antitumor and anti-mutagenic properties, making it useful in cancer research and studies focused on mutagenesis. p-Coumaric acid-13C3 serves as a valuable tool for metabolic studies and tracking biological processes involving phenolic compounds. -
Stable Isotope
L-Serine-d2 is a deuterium-labeled form of the non-essential amino acid L-Serine. This stable isotope plays a vital role in cellular proliferation, serving as a precursor for proteins and neurotransmitters. L-Serine-d2 is utilized in metabolic studies and tracer experiments, providing insights into biochemical pathways and amino acid metabolism in various research applications. -
Stable Isotope
Isovaleric acid-13C is a stable isotope-labeled variant of isovaleric acid. This naturally occurring fatty acid is significant in metabolic studies and has implications in various biological processes, including its association with neonatal death and Jamaican vomiting sickness. It serves as a useful tracer in research involving metabolic pathways, lipid metabolism, and the study of disorders related to fatty acid metabolism. -
Stable Isotope
Sodium 3-methyl-2-oxobutanoate-d7 is a deuterium-labeled variant of Sodium 3-methyl-2-oxobutanoate, serving as a stable isotope. This compound functions as a key precursor of pantothenic acid in Escherichia coli, facilitating studies on metabolic pathways and bacterial biosynthesis. Its unique isotopic properties make it suitable for tracer experiments and quantitative analysis in metabolic research. -
Stable Isotope
Disodium succinate-d4 is a deuterium-labeled derivative of disodium succinate. As a stable isotope, it serves as a valuable tracer in metabolic studies, particularly in the tricarboxylic acid cycle. This compound can be utilized in various research applications, including metabolic flux analysis and isotopic labeling experiments in both aerobic and anaerobic metabolism. -
Stable Isotope
L-Tyrosine-3,5-13C2 is a stable isotope of the non-essential amino acid L-Tyrosine, featuring carbon-13 labeling at the 3 and 5 positions. This compound can be utilized to investigate metabolic pathways and enzyme interactions, specifically in studies assessing the inhibition of citrate synthase activity in the posterior cortex. Its unique labeling allows for enhanced tracking in biochemical assays, aiding research in amino acid metabolism and neurological functions. -
Stable Isotope
Spermidine-d8 hydrochloride is a deuterium-labeled derivative of spermidine, functioning as a stable isotope for biochemical applications. This compound plays a critical role in enhancing cell membrane stability, elevating antioxidant enzyme activities, and improving the overall function of photosystem II (PSII). Additionally, spermidine-d8 hydrochloride has been shown to significantly reduce levels of hydrogen peroxide (H2O2) and superoxide anion (O2.-), making it valuable for research into oxidative stress and cellular signaling pathways. -
Stable Isotope
D-Xylulose-2-13C is a stable isotope-labeled form of D-xylulose, which serves as a crucial precursor in the biosynthesis of D-arabitol. Its isotopic labeling allows for precise tracking and quantification in metabolic studies. This compound is particularly valuable for researchers investigating carbohydrate metabolism and the role of pentoses in biological systems. -
Stable Isotope
Indole-15N is a stable isotope-labeled form of indole, a naturally occurring metabolite involved in various biological processes. This compound can be utilized in metabolic studies, tracer experiments, and as a precursor for the synthesis of nitrogen-containing compounds. The incorporation of the stable nitrogen isotope enables precise tracking and quantification in biological systems, making it a valuable tool for research in biochemistry, pharmacology, and molecular biology. -
Stable Isotope
alpha-D-glucose-d7 is the deuterium-labeled form of alpha-D-glucose, serving as a stable isotope. This compound functions as an endogenous metabolite, playing a crucial role in metabolic studies and tracer experiments. It is widely used in research applications involving metabolic pathways, isotopic labeling, and the analysis of glucose metabolism in various biological systems.
