7α-Hydroxy-4-cholesten-3-one-d7 is a deuterium-labeled analogue of 7α-Hydroxy-4-cholesten-3-one, which serves as an intermediate in bile acid synthesis from cholesterol. This compound acts as an agonist for the pregnane X receptor (PXR) and is recognized as a biomarker for bile acid loss, irritable bowel syndrome, and various conditions linked to impaired bile acid biosynthesis. Additionally, 7α-Hydroxy-4-cholesten-3-one is a physiological substrate for the enzyme CYP8B1, making it valuable for research in metabolic and gastrointestinal disorders.
7α-Hydroxy-4-cholesten-3-one-d7 is a deuterium-labeled analogue of 7α-Hydroxy-4-cholesten-3-one, which serves as an intermediate in bile acid synthesis from cholesterol. This compound acts as an agonist for the pregnane X receptor (PXR) and is recognized as a biomarker for bile acid loss, irritable bowel syndrome, and various conditions linked to impaired bile acid biosynthesis. Additionally, 7α-Hydroxy-4-cholesten-3-one is a physiological substrate for the enzyme CYP8B1, making it valuable for research in metabolic and gastrointestinal disorders.
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