Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
2'-Deoxycytidine-13C9,15N3 is a stable isotope-labeled form of the nucleoside 2'-deoxycytidine, featuring carbon-13 and nitrogen-15 isotopes. It serves as a valuable tool in metabolic studies and tracing experiments due to its ability to participate in nucleic acid metabolism. This reagent can also inhibit the biological effects of bromodeoxyuridine (BrdU), making it useful in studies pertaining to DNA synthesis and cellular proliferation. Researchers can employ 2'-Deoxycytidine-13C9,15N3 in various biological assays to explore cellular processes involving nucleotides and their derivatives. -
Stable Isotope
L-Leucine-18O2 is the stable isotope-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) known to activate the mTOR signaling pathway. This compound is utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and protein synthesis. Its stable isotope labeling enables precise quantification and tracking of L-Leucine in biological systems, making it valuable for research in nutrition, exercise physiology, and cellular signaling. -
Stable Isotope
N-Acetylglycine-d2 is a deuterated isotope of N-Acetylglycine, primarily utilized as a stable isotope for scientific research. This compound serves as a flavor enhancer and demonstrates sensory properties similar to monosodium glutamate (MSG), making it valuable in food science studies. Its applications extend to metabolic studies, tracing synthesis pathways, and flavor profile analysis in nutritional research. -
Stable Isotope
Homogentisic acid-13C6 is a stable isotope-labeled form of homogentisic acid, a phenolic acid metabolite. This compound is significant in the diagnosis of alkaptonuria, a rare metabolic disorder characterized by the accumulation of homogentisic acid in urine and serum. Homogentisic acid-13C6 can be utilized in research applications involving metabolic tracking and the study of enzymatic pathways related to phenolic acid metabolism. -
Stable Isotope
1-Dodecanol-d25 is a deuterium-labeled form of 1-Dodecanol, a long-chain alcohol that serves as an endogenous metabolite. This stable isotope is primarily utilized in metabolic studies and tracer experiments, allowing for precise tracking of metabolic pathways and interactions in biological systems. Its incorporation into research can enhance the understanding of lipid metabolism and biological processes involving fatty alcohols. -
Stable Isotope
DPPC-13C2 is a stable isotope-labeled form of dipalmitoylphosphatidylcholine (DPPC), a phospholipid that serves as a primary component of pulmonary surfactant. This compound can be utilized to prepare lipid monolayers, bilayers, and liposomes, facilitating various biophysical studies. Additionally, DPPC-liposomes have demonstrated efficacy as a delivery vector, eliciting immune responses against glycosphingolipid antigens in murine models, making it a valuable reagent for research in lipid biochemistry and immunology. -
Stable Isotope
DPPC-d71 is a deuterated form of dimyristoylphosphatidylcholine (DPPC) known for its stable isotope properties. This zwitterionic phosphoglyceride is primarily utilized in the formation of liposomal monolayers, serving as an effective delivery system for targeting glycospingolipid (GSL) antigens. Researchers employ DPPC-d71 in studies involving immunological responses and lipid-based drug delivery mechanisms, enhancing the understanding of membrane interactions and immune activation pathways. -
Stable Isotope
H-HoArg-OH-d4 is a deuterium-labeled form of H-HoArg-OH, which serves as a potent inhibitor of human bone and liver alkaline phosphatase. This stable isotope is valuable for research applications involving enzyme kinetics, metabolic studies, and pharmacokinetic analyses. Its isotopic labeling facilitates precise tracking and quantification in various biological systems. -
Stable Isotope
D-Panthenol-d6 is a deuterium-labeled derivative of D-Panthenol, which serves as a stable isotope. It acts as a biologically active form of pantothenic acid, promoting increased levels of coenzyme A within cells. This reagent is valuable for research applications involving metabolic studies, tracer studies, and quantification of cellular coenzyme A levels. -
Stable Isotope
Adrenosterone-d10 is a deuterium-labeled derivative of Adrenosterone, specifically designed as a stable isotope for advanced research applications. As a competitive inhibitor of 11-beta hydroxysteroid dehydrogenase 1 (HSD11β1), Adrenosterone demonstrates key biological activity by modulating steroid metabolism. This compound exhibits weak androgenic effects and has been studied for its potential in inhibiting metastatic progression in human cancer cells, as well as its role in influencing body composition through fat reduction and muscle mass increase. -
Stable Isotope
Cholestenone-13C is a stable isotope-labeled form of Cholestenone (4-Cholesten-3-one), an intermediate oxidation product of cholesterol primarily metabolized in the liver. This compound exhibits significant mobility within cellular membranes, affecting cholesterol flip-flop dynamics and efflux processes. Cholestenone-13C is valuable for research applications involving lipid metabolism and the role of cholesterol derivatives in cellular functions, providing insights into potential long-term functional defects associated with cholesterol metabolism. -
Stable Isotope
DL-Mevalonolactone-d7 is a deuterium-labeled stable isotope derivative of DL-Mevalonolactone, a key intermediate in the mevalonate pathway. This compound has been shown to decrease mitochondrial membrane potential, reduce NAD(P)H levels, and impair calcium retention in neuronal tissues, ultimately leading to mitochondrial swelling. It is useful for studies involving mitochondrial function, metabolic pathways, and isotopic tracing in biochemical research. -
Stable Isotope
Pyruvic acid-13C2 is a stable isotope-labeled form of pyruvic acid, a crucial intermediate in the metabolic pathways of carbohydrates, proteins, and fats. This reagent facilitates precise metabolic studies and tracer experiments, providing insight into cellular respiration and energy production. It is valuable in biochemical research, particularly in flux analysis and metabolic profiling. -
Stable Isotope
L-Proline-13C5 is a stable isotope-labeled form of the amino acid L-Proline, where five carbon atoms are labeled with carbon-13. L-Proline plays a critical role as a building block of proteins and is involved in collagen synthesis and cellular metabolism. This reagent is essential for isotopic labeling studies, metabolic flux analysis, and tracking biochemical pathways, providing valuable insights into protein synthesis and metabolic activities in various biological systems. -
Stable Isotope
L-Methionine-13C is the stable isotope-labeled form of the essential amino acid L-Methionine. Important for human development, Methionine serves as a crucial building block for protein synthesis and exhibits hepatoprotective properties. This reagent is valuable for metabolic studies, tracing amino acid pathways, and examining the role of Methionine in various biological processes. -
Stable Isotope
3-Hydroxybutyric acid-d4 sodium is a stable isotope-labeled form of 3-Hydroxybutyric acid. This metabolite, known for its elevation in type I diabetes, plays a crucial role in metabolic processes and can influence the properties of membrane lipids. Research applications include metabolic studies, isotope tracing in biochemical pathways, and investigations into the physiological effects of β-Hydroxybutyric acid. -
Stable Isotope
Urea-13C,15N2 is a stable isotope-labeled compound featuring both 13C and 15N isotopes. Urea serves as an effective protein denaturant through direct and indirect mechanisms, demonstrating key biological activity and therapeutic properties, including its role as an emollient and keratolytic agent. It is commonly utilized in research applications, such as evaluating renal function via blood urea nitrogen (BUN) measurements. Additionally, Urea-13C,15N2 is significant in agricultural and chemical industries as a nitrogen source. -
Stable Isotope
L-Methionine-13C,d3 is a stable isotope-labeled form of the essential amino acid L-Methionine, featuring both carbon-13 and deuterium labeling. L-Methionine plays a crucial role in human development and functions as a hepatoprotectant, supporting liver health. This reagent is valuable for metabolic studies, isotopic tracing experiments, and research into amino acid metabolism. -
Stable Isotope
Hippuric acid-d5 is a deuterated form of hippuric acid, a metabolite resulting from the conjugation of benzoic acid and glycine. This stable isotope serves as a valuable tool for tracking metabolic pathways and understanding the excretion of aromatic compounds from dietary sources. Its applications include pharmacokinetic studies and metabolic profiling in various biochemical research settings. -
Stable Isotope
Estradiol-d4 is a deuterated form of the steroid hormone estradiol, functioning as a stable isotope. It plays a critical role in regulating fertility and the development of secondary sexual characteristics in females. Estradiol-d4 is utilized in research to study estrogen signaling, particularly its influence on interleukin-6 (IL-6) expression via the estrogen receptor β (ERβ) pathway, enabling precise quantification and analysis in various biological studies. -
Stable Isotope
L-Leucine-13C6,15N is a stable isotope-labeled form of L-Leucine, incorporating both carbon-13 and nitrogen-15 isotopes. This essential branched-chain amino acid (BCAA) plays a crucial role in activating the mTOR signaling pathway, which is important for regulating cell growth and metabolism. L-Leucine-13C6,15N is widely utilized in metabolic studies and tracer experiments to investigate protein synthesis and amino acid metabolism in various biological systems. -
Stable Isotope
L-Aspartic acid-d3 is a deuterium-labeled analog of L-Aspartic acid, known for its ability to penetrate the blood-brain barrier. This amino acid plays a significant role in various metabolic pathways and is utilized in synthesizing prodrugs aimed at colon and cecal tissues. Additionally, L-Aspartic acid-d3 is valuable in research on inflammatory conditions, enabling precise tracking and assessment of metabolic processes. -
Stable Isotope
L-Cysteine-d3 is a deuterium-labeled derivative of L-Cysteine, a conditionally essential amino acid. This compound serves as a precursor for key biological molecules, including hydrogen sulfide (H2S), glutathione, and taurine. L-Cysteine-d3 is valuable for research applications investigating metabolic pathways, appetite regulation, and the synthesis of reactive sulfur species. Its stable isotope labeling facilitates the study of L-Cysteine's roles in various physiological processes. -
Stable Isotope
L-Aspartic acid-13C4 is a stable isotope-labeled variant of L-Aspartic acid, an amino acid capable of crossing the blood-brain barrier. This compound is utilized in research focusing on prodrug formulation to effectively target colon and cecal tissues. Additionally, L-Aspartic acid-13C4 serves as a valuable tool in studying various inflammatory conditions, enhancing the understanding of metabolic and pathological processes. -
Stable Isotope
L-Proline-d3 is a deuterium-labeled derivative of L-Proline, an essential amino acid integral to protein synthesis in living organisms. This stable isotope serves as a valuable tool in biochemical research, particularly in studies involving metabolic pathways, protein folding, and structure-function relationships of proteins. Its unique labeling facilitates advanced analytical techniques, including NMR and mass spectrometry, enabling precise tracking of metabolic processes and biomolecular interactions. -
Stable Isotope
Benzyl alcohol-d1 is a deuterium-labeled derivative of benzyl alcohol, serving as a stable isotope. It is primarily utilized in research applications such as mass spectrometry and metabolic studies, enabling the tracing of biological pathways and the quantitation of metabolites. Its distinct isotopic signature allows for enhanced specificity in chemical analysis and improved detection limits in various experimental setups. -
Stable Isotope
Fumaric acid-13C4 is a stable isotope-labeled form of fumaric acid, primarily utilized in metabolic studies and tracer experiments. Fumaric acid is recognized as an oncometabolite, implicated in fumarase deficiency and various cancer-related processes. The incorporation of the 13C label facilitates advanced research applications, including metabolic flux analysis and the investigation of biochemical pathways associated with cancer metabolism. -
Stable Isotope
3-Indoleacetic acid-d7 is a deuterium-labeled derivative of 3-Indoleacetic acid, a pivotal auxin and plant growth hormone. This stable isotope is employed in various research applications, particularly in studies investigating the mechanisms of plant growth and development. By incorporating 3-Indoleacetic acid-d7 into cell culture mediums, researchers can effectively explore the dynamics of cell elongation and division in plant systems. -
Stable Isotope
Glycolic acid-d2 is a deuterium-labeled variant of glycolic acid, functioning as a stable isotope. It acts as a selective inhibitor of tyrosinase, effectively suppressing melanin production, which can lead to skin lightening effects. This reagent is valuable for studies in skin biology, cosmetic research, and investigations into pigmentation processes. -
Stable Isotope
Glycerol-13C3 is a stable isotope-labeled form of glycerol, featuring three carbon-13 atoms. It serves as a valuable tool in sample preparation and is commonly employed in polyacrylamide gel electrophoresis to enhance the sensitivity of detection methods. The incorporation of Glycerol-13C3 allows for precise quantification and tracking of metabolic pathways in various biological studies. -
Stable Isotope
Hypoxanthine-d4 is a deuterium-labeled derivative of hypoxanthine, which serves as a stable isotope. It exhibits potential as a free radical generator and can be utilized as an indicator of hypoxic conditions. This compound is suitable for research applications focused on metabolism, hypoxia-related studies, and oxidative stress investigations, providing a valuable tool for analyzing purine metabolism and its implications in various biological processes. -
Stable Isotope
Cholesterol-13C2 is a stable isotope-labeled form of cholesterol, a critical sterol in mammalian biology. It constitutes 20-25% of the plasma membrane's structural components and is essential for regulating the fluidity and permeability of the membrane, influencing the behavior of transporters and signaling proteins. This compound also acts as an endogenous agonist for estrogen-related receptor α (ERRα), making it valuable for studies in cell membrane dynamics and receptor signaling in various biological contexts. -
Stable Isotope
3,4-Dihydroxybenzeneacetic acid-d5 is a deuterated stable isotope of 3,4-Dihydroxybenzeneacetic acid, which serves as a primary neuronal metabolite of dopamine. This labeled compound is essential for studying dopamine metabolism and its related pathways in neurological research. It provides valuable insights into the dynamics of neurotransmitter activity and can be utilized in various analytical techniques, including mass spectrometry and nuclear magnetic resonance spectroscopy. -
Stable Isotope
L-Alanine-d3 is a stable isotope of the non-essential amino acid L-Alanine, distinguished by the presence of deuterium. This compound plays a vital role in metabolic processes, particularly in sugar and acid metabolism. L-Alanine-d3 is utilized in various research applications, including studies of metabolic pathways, amino acid transport, and the tracing of metabolic processes in biological systems. Its incorporation into research provides enhanced analytical accuracy in understanding amino acid dynamics and energy production in tissues. -
Stable Isotope
Indole-d7 is a deuterium-labeled derivative of indole, serving as a stable isotope in chemical research. As an endogenous metabolite, indole plays a crucial role in various biological processes, including neurotransmitter synthesis and tryptophan metabolism. Indole-d7 is primarily utilized in mass spectrometry and other analytical techniques for metabolic tracing and studying metabolic pathways. Its isotopic labeling aids in quantifying concentrations and analyzing the kinetics of indole-related biological effects. -
Stable Isotope
p-Cresol sulfate-d7 potassium is a deuterium-labeled derivative of p-Cresyl sulfate, a known protein-bound uremic toxin. This stable isotope is utilized in metabolic studies and pharmacokinetic research to trace the behavior of p-Cresyl sulfate in biological systems. Its incorporation into research enables enhanced understanding of protein binding and uremic toxicity in clinical settings. -
Stable Isotope
Taurocholic acid-d4 sodium is a deuterium-labeled derivative of taurocholic acid, a bile acid primarily involved in the emulsification of dietary fats. This stable isotope is valuable for research applications, particularly in metabolic studies and tracer experiments that investigate lipid digestion and absorption. It can be utilized in mass spectrometry and other analytical techniques to trace metabolic pathways and quantify bile acid levels in biological samples. -
Stable Isotope
p-Coumaric acid-d6 is a deuterium-labeled derivative of p-Coumaric acid, a prominent isomer of cinnamic acid. This compound exhibits notable antitumor and anti-mutagenic properties, making it valuable for cancer research and mutagenesis studies. Its stable isotope labeling facilitates quantitative analysis and metabolic tracking in biochemical research applications. -
Stable Isotope
L-Threonine-13C4 is a stable isotope-labeled form of the amino acid L-Threonine. As a naturally occurring amino acid, L-Threonine plays a critical role in protein synthesis and is utilized widely in biochemical research. This stable isotope can be employed in metabolic studies, tracer experiments, and quantitative analyses to track metabolic pathways and protein dynamics in various biological systems. -
Stable Isotope
L-Tryptophan-d8 is a deuterium-labeled form of the essential amino acid L-Tryptophan, serving as a stable isotope for various research applications. It is a precursor to important biomolecules such as serotonin, melatonin, and vitamin B3. This reagent is valuable in metabolic studies, isotopic labeling experiments, and investigations of amino acid metabolism, aiding in the understanding of biological processes and drug development. -
Stable Isotope
L-Serine-d3 is a deuterium-labeled form of the non-essential amino acid L-Serine, which plays a crucial role in cellular proliferation and metabolic processes. This stable isotope is useful in research applications involving metabolic tracing and NMR spectroscopy. L-Serine-d3 allows for enhanced detection and quantification in various biochemical studies, thereby aiding in the understanding of amino acid metabolism and related pathways. -
Stable Isotope
i-Inositol-d6 is a deuterium-labeled form of i-Inositol, a naturally occurring compound involved in various biological processes. It serves as an important precursor for inositol phosphates and plays a critical role in cell signaling and membrane formation. This stable isotope is widely used in metabolic studies and tracer experiments to investigate cellular pathways and lipid metabolism. -
Stable Isotope
Estradiol-d5 is a deuterium-labeled derivative of estradiol, a steroid sex hormone essential for female fertility and the development of secondary sexual characteristics. This stable isotope serves as a valuable tool in research applications, particularly in metabolic studies and hormone tracking. Estradiol-d5 activates the estrogen receptor β (ERβ) pathway, leading to the upregulation of IL-6 expression, making it useful for investigating estrogen-related biological processes. -
Stable Isotope
Glutaric acid-d6 is a stable isotope-labeled form of glutaric acid, an important intermediate in the catabolic pathways of lysine and tryptophan. It plays a significant role in modulating pericyte contractility and migration, making it relevant for studies in cellular dynamics and pathology. Additionally, glutaric acid is an important biomarker for diagnosing glutaric aciduria type I, facilitating research in metabolic disorders. -
Stable Isotope
1-Methyl-L-histidine-d3 is a deuterium-labeled form of 1-Methyl-L-histidine, utilized as a stable isotope in metabolic studies. This compound serves as a valuable biomarker for quantifying meat consumption and the intake of exogenous 3-methylhistidine (3MH). Researchers can apply this reagent in dietary assessments and metabolic tracing to better understand protein turnover and the physiological effects of meat-derived amino acids. -
Stable Isotope
Hippuric acid-d2 is the deuterium-labeled form of hippuric acid, a stable isotope used in various analytical applications. As a metabolite of aromatic compounds, it plays a key role in studies involving metabolic pathways and biochemistry. Its incorporation in research can enhance the accuracy of metabolic profiling and pharmacokinetic studies, providing insights into the metabolism of aromatic substances in biological systems. -
Stable Isotope
L-Citrulline-d4 is the deuterium-labeled analog of the amino acid L-Citrulline, which plays a critical role in the urea cycle and the production of nitric oxide. This stable isotope is utilized in metabolic studies and pharmacokinetic research to trace metabolic pathways involving citrulline. Its applications include investigating amino acid metabolism and exploring nitric oxide-mediated physiological processes. -
Stable Isotope
L-Serine-13C is a stable isotope-labeled form of L-Serine, an amino acid fundamental to various biological processes. It plays a critical role in cellular proliferation and is involved in the synthesis of proteins and neurotransmitters. This reagent is particularly useful for metabolic studies, isotopic tracing experiments, and research related to amino acid metabolism. -
Stable Isotope
DEHP-d4 is a deuterated form of bis(2-ethylhexyl) phthalate (DEHP), serving as a stable isotope. This compound is utilized in biological studies to trace and quantify metabolic pathways involving DEHP, an endogenous metabolite. Its incorporation into research allows for enhanced accuracy in the analysis of phthalate exposure and its effects on biological systems. -
Stable Isotope
p-Tyramine-d4 hydrochloride is a deuterium-labeled variant of tyramine hydrochloride, which serves as a stable isotope for analytical applications. This compound is involved in the regulation of blood pressure and is naturally occurring in various foods and biological systems. It can be utilized in metabolic studies and tracing experiments to elucidate the role of tyramine in physiological processes.
