Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
L-Aspartic acid-15N is a stable isotope-labeled form of the amino acid L-Aspartic acid. This compound plays a crucial role in various metabolic processes and is known for its ability to penetrate the blood-brain barrier. L-Aspartic acid-15N is primarily applied in the development of prodrugs targeting colon and cecal tissues and is also utilized in research related to inflammatory conditions. Its isotopic labeling allows for advanced studies in metabolic tracking and related biochemical pathways. -
Stable Isotope
Cinnamic acid-d6 is a deuterium-labeled derivative of cinnamic acid, serving as a stable isotope for analytical studies. Cinnamic acid is recognized for its potential anti-cancer properties, exhibiting IC50 values between 1-4.5 mM in various cancer cell lines, including glioblastoma, melanoma, prostate, and lung carcinoma. This compound is valuable for research applications that require tracking metabolic pathways, studying drug interactions, and understanding the mechanisms of action in cancer biology. -
Stable Isotope
L-Serine-d7 is a deuterated form of the non-essential amino acid L-Serine, serving as a stable isotope labeled compound. L-Serine is vital for cellular processes, including proliferation and metabolism. This reagent is primarily utilized in metabolic studies, tracer experiments, and proteomic analyses, enhancing the understanding of amino acid metabolism and biological pathways. -
Stable Isotope
L-Cysteine-13C3 is a stable isotope-labeled form of the conditionally essential amino acid L-Cysteine. This compound serves as a crucial precursor for biologically active molecules, including hydrogen sulfide (H2S), glutathione, and taurine, which are integral to various metabolic pathways. L-Cysteine is also noted for its role in appetite regulation, as it has been shown to suppress ghrelin levels in both rodent models and human studies. This reagent is valuable for metabolic studies and investigations into amino acid metabolism. -
Stable Isotope
L-Isoleucine-13C6 is a stable isotope-labeled form of the essential amino acid L-Isoleucine, which exhibits hydrophobic properties. As a nonpolar amino acid, L-Isoleucine plays a critical role in protein synthesis and energy production. This reagent is primarily utilized in metabolic studies, isotopic labeling experiments, and protein tracking to elucidate metabolic pathways and cellular processes. -
Stable Isotope
L-Ornithine-1,2,3,4,5-13C5 hydrochloride is a stable isotope-labeled form of the amino acid L-Ornithine. This compound is integral to the urea cycle, facilitating the excretion of excess nitrogen in the body. Its unique isotopic labeling makes it a valuable tool for metabolic studies and tracer experiments in biochemical research. -
Stable Isotope
L-Citrulline-d7 is a stable isotope-labeled form of L-Citrulline, an amino acid involved in various metabolic processes. It plays a critical role in the conversion of arginine to nitric oxide, impacting vasodilation and blood flow regulation. L-Citrulline-d7 is utilized in research applications such as metabolic studies, tracer kinetics, and pharmacokinetic investigations to provide insights into amino acid metabolism and related physiological functions. -
Stable Isotope
TRIA-662-d3 is a deuterium-labeled analog of TRIA-662, also known as 1-Methylnicotinamide chloride, which serves as an endogenous metabolite. This compound demonstrates significant antithrombotic and anti-inflammatory properties, making it a valuable tool for research in cardiovascular and inflammatory conditions. TRIA-662-d3 can be utilized in studies exploring metabolic pathways and for profiling biological activities in various assays. -
Stable Isotope
L-Pyroglutamic acid-d5 is a deuterium-labeled derivative of L-Pyroglutamic acid, which serves as a stable isotope for various research applications. The levo-isomer of pyroglutamic acid is biologically active in humans and plays a significant role as an intermediate in glutathione metabolism. This compound is useful in studies involving metabolic pathways, isotopic labeling, and tracer experiments in biochemical research. -
Stable Isotope
Stearic acid-d35 is a deuterium-labeled derivative of stearic acid, a long-chain saturated fatty acid commonly found in both animal and vegetable fats and oils. This stable isotope serves as a valuable tracer in metabolic studies and various biochemical assays, enabling researchers to investigate lipid metabolism and fatty acid incorporation. Applications include studying lipid profiles, dietary impacts, and metabolic pathways in diverse biological systems. -
Stable Isotope
Indole-3-acetamide-d5 is a deuterium-labeled derivative of Indole-3-acetamide, serving as a stable isotope for research applications. As an intermediate in the biosynthesis of indole-3-acetic acid, it plays a critical role in the synthesis of this essential plant growth hormone classified under auxins. This compound is valuable for studies investigating hormone biosynthesis, metabolic pathways, and plant growth regulation. -
Stable Isotope
Cholesterol-d6 is a deuterium-labeled form of cholesterol, a key sterol that constitutes 20-25% of the structural components of mammalian plasma membranes. It significantly influences membrane fluidity and permeability while modulating the activity of transporters and signaling proteins. In addition to its structural roles, cholesterol acts as an endogenous agonist for estrogen-related receptor α (ERRα), making Cholesterol-d6 valuable for studies in membrane biology and receptor interactions. Its stable isotope labeling aids in quantitative analyses of cholesterol dynamics in various biological systems. -
Stable Isotope
L-Serine-13C3,15N is a stable isotope-labeled form of L-Serine, incorporating three carbon-13 and one nitrogen-15 atoms. As a key non-essential amino acid, L-Serine is vital for various biological processes, including cellular proliferation and metabolism. This reagent is widely used in studies involving metabolic tracing, isotope labeling experiments, and amino acid metabolism research. -
Stable Isotope
N-Acetylglycine-d5 is a deuterium-labeled derivative of N-Acetylglycine, a naturally occurring compound found in various food sources. As a stable isotope, it serves as a valuable internal standard for analytical chemistry, particularly in mass spectrometry applications. Its unique labeling allows for precise quantification and tracing of metabolic pathways, making it useful in nutritional studies and flavor enhancement research. -
Stable Isotope
Glycocholic acid-d4 is a deuterium-labeled form of Glycocholic acid, a bile acid known for its anticancer properties. It primarily targets both pump resistance-related and non-pump resistance-related pathways, making it a valuable tool in cancer research. The stable isotope labeling enables precise tracking and quantification in biological studies, supporting investigations into the mechanisms of bile acids in cancer and drug resistance. -
Stable Isotope
Urea-15N2 is a stable isotope-labeled form of urea, incorporating nitrogen-15. This compound serves as a potent protein denaturant through both direct and indirect mechanisms, facilitating various biochemical studies. Its applications extend to evaluating renal function via blood urea nitrogen (BUN) measurements, as well as serving as a diuretic agent. Additionally, Urea-15N2 finds utility in agricultural research and the chemical industry as a nitrogen source for fertilizers and other products. -
Stable Isotope
Ethylene glycol-d4 is a deuterium-labeled form of ethylene glycol, serving as a stable isotope for various analytical applications. It is primarily utilized in NMR (nuclear magnetic resonance) spectroscopy to provide insight into molecular structure and dynamics. This compound is valuable in metabolomics studies, enabling researchers to trace metabolic pathways and interactions in biological systems. -
Stable Isotope
Allantoin-13C2,15N4 is a stable isotope-labeled derivative of Allantoin, featuring isotopic labeling at carbon and nitrogen positions. Allantoin functions as a skin conditioning agent, promoting healthy skin and stimulating the growth of new and healthy tissues. This compound is valuable for research applications in dermatological studies and metabolic labeling experiments. -
Stable Isotope
2-Methylcitric acid-d3 is a deuterium-labeled derivative of 2-Methylcitric acid, which functions as a stable isotope useful in metabolic studies. This compound is a key metabolite in the 2-methylcitric acid cycle, accumulating in conditions such as methylmalonic and propionic acidemias, thereby serving as a valuable biomarker. Additionally, 2-Methylcitric acid is known to significantly inhibit ADP-stimulated and uncoupled respiration in mitochondria when supported by glutamate, making it relevant for research on mitochondrial function and metabolic disorders. -
Stable Isotope
Heptadecanoic acid-d33 is a deuterated form of heptadecanoic acid, an odd-chain saturated fatty acid (OCS-FA). This stable isotope is utilized in metabolic studies to investigate fatty acid metabolism and its implications in various diseases, including coronary heart disease, prediabetes, and type 2 diabetes, as well as multiple sclerosis. Its specific labeling allows for enhanced tracking and analysis in biochemical research and clinical studies focused on lipid profiles and disease associations. -
Stable Isotope
L-Isoleucine-15N is the stable isotope-labeled form of the essential amino acid L-Isoleucine. As a nonpolar hydrophobic amino acid, it plays a critical role in protein synthesis and metabolism. This reagent is particularly valuable in tracer studies and metabolic research, allowing for the precise tracking of amino acid metabolism and incorporation into proteins in various biological systems. -
Stable Isotope
L-Tryptophan-13C is a stable isotope-labeled form of the essential amino acid L-Tryptophan. Serving as a precursor to important biomolecules such as serotonin, melatonin, and vitamin B3, L-Tryptophan-13C is utilized in metabolic studies, tracer experiments, and other research applications that require isotopic labeling to track biochemical pathways and mechanisms in living systems. -
Stable Isotope
3-Hydroxyglutaric acid-d5 is a deuterated form of 3-Hydroxyglutaric acid, making it a stable isotope reagent. This compound serves as a valuable tool for metabolic studies and isotopic tracing in biochemical research. Its unique labeling allows for enhanced sensitivity in detection methods such as mass spectrometry, facilitating investigations into metabolic pathways and disorders associated with glutaric acid metabolism. -
Stable Isotope
L-Proline-d7 is a deuterated form of the amino acid L-Proline, functioning as a stable isotope tracer. It is utilized in metabolic studies and isotopic labeling experiments, enhancing the understanding of protein synthesis and metabolism. This compound is instrumental in various biological applications, including NMR spectroscopy and mass spectrometry, to track metabolic pathways and protein interactions in living organisms. -
Stable Isotope
Oxalic acid-13C2 is a stable isotope-labeled form of oxalic acid, a strong dicarboxylic acid found in various plants and vegetables. This reagent is primarily utilized in analytical chemistry applications and serves as a general reducing agent. Its isotopic labeling makes it particularly valuable for metabolic studies and tracer experiments, facilitating the investigation of biochemical pathways and compound interactions in research settings. -
Stable Isotope
D-Glucose-d7 is a deuterated form of D-Glucose, serving as a stable isotope for various biological applications. As a primary monosaccharide in cellular metabolism, D-Glucose plays a vital role in energy production and is involved in cellular signaling related to metabolic status and stress responses. This reagent is commonly used in isotopic labeling studies to investigate metabolic pathways, enabling enhanced analysis in biochemical research and metabolic tracing experiments. -
Stable Isotope
Cholic acid-d5 is a deuterium-labeled derivative of cholic acid, a key primary bile acid synthesized in the liver, often conjugated with glycine or taurine. It plays a critical role in the emulsification of fats, enhancing fat absorption and promoting cholesterol excretion. This stable isotope is particularly useful in metabolic studies, tracer experiments in lipid metabolism, and bile acid research. -
Stable Isotope
D-Phenylalanine-d5 is a deuterium-labeled form of D-Phenylalanine, the synthetic dextro isomer of phenylalanine. This stable isotope is utilized in studies assessing metabolic pathways and pharmacokinetics. Notably, D-Phenylalanine exhibits inhibitory effects on biofilm formation in Pseudoalteromonas sp. SC2014, making it significant for research in biofilm-associated infections and antimicrobial strategies. -
Stable Isotope
Octanoic acid-d15 is the deuterium-labeled form of octanoic acid, also known as caprylic acid. This stable isotope is utilized in various research applications, including metabolic studies and tracer experiments, allowing for precise tracking of fatty acid metabolism. Octanoic acid itself is recognized for its role in ester production, particularly in perfumery and dye manufacturing. -
Stable Isotope
L-Tyrosine-13C6 is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine. This compound can modulate metabolic pathways by inhibiting citrate synthase activity, particularly in the posterior cortex. L-Tyrosine-13C6 is utilized in research applications focusing on metabolic studies, amino acid metabolism, and neurobiological research. -
Stable Isotope
L-Tyrosine-13C9 is a stable isotope-labeled form of the non-essential amino acid L-Tyrosine, featuring nine carbon-13 atoms. This compound is utilized in metabolic studies to trace the biosynthesis of proteins and other biomolecules. Key applications include investigating metabolic pathways and assessing the inhibition of citrate synthase activity, particularly in the posterior cortex, to understand its role in neurobiology and related fields. -
Stable Isotope
L-5-Hydroxytryptophan-d3 is a deuterium-labeled derivative of L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid that serves as a precursor to the neurotransmitter serotonin. Its primary biological activity includes modulation of serotonin levels, making it useful in investigations related to mood disorders, appetite control, and sleep regulation. L-5-Hydroxytryptophan-d3 is employed in various research applications, including studies on fibromyalgia, migraine management, and myoclonus, where precise tracing of biochemical pathways is essential. -
Stable Isotope
Spermidine-d6 is a deuterium-labeled analog of spermidine, a key polyamine involved in cellular functions. It has been shown to enhance cell membrane stability and elevate antioxidant enzyme activities, thus promoting the efficiency of photosystem II (PSII). Additionally, spermidine-d6 significantly reduces hydrogen peroxide and superoxide levels, making it valuable for research related to oxidative stress and cellular resilience. -
Stable Isotope
N-Acetyl-L-aspartic acid-d3 is a stable isotope-labeled form of N-Acetyl-L-aspartic acid, which serves as an acetyl donor and is an important derivative of aspartic acid. This compound plays a crucial role in brain metabolism and is utilized in research focused on neurodegenerative diseases, including Canavan disease. Its stable isotope labeling aids in metabolic studies and tracking biochemical pathways involving N-Acetyl-L-aspartic acid in neurological contexts. -
Stable Isotope
Hypoxanthine-15N4 is a stable isotope-labeled form of hypoxanthine, a purine derivative. This compound serves as a potential free radical generator and can be utilized as a biomarker for hypoxia in various biological studies. Its unique labeling allows for precise tracking and analysis in metabolic research and cellular assays. -
Stable Isotope
Stearic acid-13C18 is a stable isotope-labeled form of stearic acid, a long-chain saturated fatty acid found in various animal and plant fats and oils. As a stable isotope, it serves as a valuable tracer in metabolic studies, enabling researchers to investigate fatty acid metabolism and biological pathways involving lipid synthesis and oxidation. This reagent is essential for applications in nutritional research, pharmacokinetics, and the study of lipid-related disorders. -
Stable Isotope
(S)-Malic acid-d3 is a deuterated form of (S)-malic acid, specifically designed for use in stable isotope labeling applications. This naturally occurring dicarboxylic acid is known for its contribution to the characteristic sour flavor of fruits and serves as an important food additive. In chemical research, (S)-malic acid-d3 can be employed in metabolic studies, tracer experiments, and the investigation of biochemical pathways involving malate metabolism. -
Stable Isotope
L-Tryptophan-d3 is a deuterium-labeled form of the essential amino acid L-Tryptophan. This compound serves as a precursor for the biosynthesis of important neurotransmitters such as serotonin and melatonin, as well as vitamin B3. L-Tryptophan-d3 is widely utilized in metabolic studies, isotope labeling experiments, and research focused on sleep regulation and mood disorders. Its stable isotope properties enable precise tracking of metabolic pathways in biological systems. -
Stable Isotope
Itaconic acid-13C5 is a stable isotope-labeled version of Itaconic acid, which serves as a critical building block for polymers, chemicals, and biofuels. This metabolite is predominantly associated with macrophages and plays a significant role in mediating interactions between macrophage metabolism and peritoneal tumors. Itaconic acid-13C5 can be utilized in metabolic studies, tracer experiments, and investigations focused on immune cell metabolism in cancer research. -
Stable Isotope
L-Tyrosine-d2 is a deuterium-labeled form of the non-essential amino acid L-Tyrosine. It serves as a stable isotope used in metabolic studies and tracer experiments. This compound is known to inhibit citrate synthase activity in the posterior cortex, making it valuable for research in neurobiology and metabolic regulation. -
Stable Isotope
L-Hydroxyproline-d3 is a deuterium-labeled derivative of L-Hydroxyproline, a key chiral building block in pharmaceutical synthesis. The stable isotope labeling facilitates quantification and tracing in metabolic studies. This compound is essential for research applications in biochemical pathways, protein structure analysis, and the development of therapeutic agents. -
Stable Isotope
D-Galactose-13C6 is a stable isotope-labeled form of D-Galactose, where carbon-13 isotopes are incorporated into the molecule. D-Galactose is a naturally occurring aldohexose and a C-4 epimer of glucose, widely utilized in metabolic studies. This reagent is valuable for tracing metabolic pathways and studying carbohydrate metabolism in various biological systems. -
Stable Isotope
4-Hydroxyphenylacetic acid-d6 is a deuterated form of 4-Hydroxyphenylacetic acid, serving as a stable isotope for research applications. This compound is a significant microbiota-derived metabolite of polyphenols and is involved in antioxidative mechanisms. It has been shown to induce the expression of the transcription factor Nrf2, making it useful for studies focused on oxidative stress and related signaling pathways. -
Stable Isotope
L-Leucine-15N is a stable isotope-labeled form of L-Leucine, an essential branched-chain amino acid that plays a critical role in protein synthesis and metabolic regulation. By activating the mTOR signaling pathway, L-Leucine-15N facilitates studies on cellular growth, metabolism, and muscle protein synthesis. This reagent is useful for research applications involving metabolic tracking, protein dynamics, and nutritional studies in various biological systems. -
Stable Isotope
Cholic acid-13C is a stable isotope-labeled form of cholic acid, a primary bile acid synthesized in the liver. This compound plays a significant role in lipid metabolism by enhancing fat absorption and promoting cholesterol excretion. Cholic acid-13C is valuable for tracing studies in metabolic research, allowing scientists to investigate bile acid dynamics and related metabolic pathways. -
Stable Isotope
Pyruvic acid-13C is a stable isotope-labeled form of pyruvic acid, which serves as a key intermediate in the metabolism of carbohydrates, proteins, and fats. This compound is widely utilized in metabolic studies and tracer studies to investigate metabolic pathways and energy production. Its incorporation into experimental designs supports research in nutrition, cellular respiration, and metabolic regulation. -
Stable Isotope
L-Carnitine-d9 is a deuterated form of L-Carnitine, an endogenous compound essential for fatty acid metabolism. It plays a crucial role in the transport of long-chain fatty acyl-CoAs into the mitochondria, facilitating their degradation through β-oxidation. This stable isotope is valuable for metabolic research and can aid in the investigation of metabolic disorders and inborn errors of metabolism where L-Carnitine’s role is significant. -
Stable Isotope
Malic acid-d3 is a deuterium-labeled derivative of malic acid (hydroxybutanedioic acid), a naturally occurring dicarboxylic acid found in various fruits, notably apples and pears. As a stable isotope, malic acid-d3 is utilized in isotopic labeling studies to trace metabolic pathways and investigate biochemical processes. This compound is valuable in numerous research applications, including metabolic flux analysis and the study of organic acid metabolism. -
Stable Isotope
L-Proline-13C5,15N is a stable isotope-labeled form of L-Proline, incorporating five carbon-13 and one nitrogen-15 isotopes. L-Proline is a non-essential amino acid that plays a crucial role in protein synthesis and cellular metabolism. This isotopic labeling allows for enhanced tracking and analysis in metabolic studies, enabling researchers to explore amino acid kinetics, protein synthesis, and metabolic pathways in various biological systems. -
Stable Isotope
Progesterone-d9 is a deuterium-labeled form of the steroid hormone progesterone, which plays a pivotal role in regulating the menstrual cycle and supporting pregnancy. As a stable isotope, Progesterone-d9 is instrumental in various analytical applications, including mass spectrometry and metabolic studies. Researchers utilize this reagent to trace metabolic pathways and assess hormone levels in biological samples, enhancing the understanding of reproductive health and endocrine functions.
