Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Spermidine-13C4 hydrochloride is a stable isotope-labeled derivative of spermidine, targeting cellular processes related to membrane stability and antioxidant activity. This compound enhances the activity of antioxidant enzymes, supports the integrity of photosystem II (PSII), and modulates relevant gene expression. Additionally, it effectively reduces hydrogen peroxide (H2O2) and superoxide (O2.-) levels, making it a valuable tool for research in cellular biology and oxidative stress studies. -
Stable Isotope
C18-Ceramide-d7 is a deuterium-labeled variant of C18-Ceramide, designed as a stable isotope applicable in metabolic studies. This compound serves as a valuable tool for tracing lipid metabolism and studying the role of ceramides in various biological processes. Its use in mass spectrometry enables precise quantification and evaluation of ceramide-related pathways in research applications. -
Stable Isotope
D-Fructose-13C is a stable isotope-labeled form of D-Fructose, an important naturally occurring monosaccharide found in various plants. This compound is primarily utilized in metabolic studies and tracer experiments to investigate carbohydrate metabolism and energy production pathways. Its stable isotope labeling allows for precise tracking in both in vitro and in vivo studies, making it a valuable tool in biochemical and nutritional research applications. -
Stable Isotope
L-Citrulline-13C is a stable isotope-labeled form of L-Citrulline, an amino acid produced from the catabolism of proline, glutamine, and glutamate, or synthesized from L-arginine through the arginine-citrulline pathway. This compound is utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and nitric oxide synthesis. Its incorporation into various biological systems allows for precise tracking of metabolic pathways and enhances the understanding of cellular functions related to cardiovascular health and exercise physiology. -
Stable Isotope
L-Methionine-13C5,15N is a stable isotope-labeled form of the essential amino acid, L-Methionine, featuring five carbon-13 and one nitrogen-15 isotopes. This compound plays a vital role in various biological processes, including protein synthesis and as a hepatoprotectant. L-Methionine-13C5,15N is commonly utilized in metabolic studies, tracer studies, and nutritional research to elucidate amino acid metabolism and the dynamics of protein turnover. -
Stable Isotope
DL-Glutamic acid-d3 is the deuterium-labeled derivative of DL-Glutamic acid, a crucial metabolite in various biological processes. This stable isotope serves as a valuable tracer in metabolic studies, allowing for precise tracking and quantification of metabolic pathways. DL-Glutamic acid's stability, compared to its L-isomer polymorphs, enhances its utility in experimental research involving amino acid metabolism and related biochemical pathways. -
Stable Isotope
Stearic acid-d5 is a deuterium-labeled derivative of stearic acid, a long-chain saturated fatty acid prevalent in various animal and vegetable fats. As a stable isotope, stearic acid-d5 serves as an important tool in metabolic studies and tracer experiments, enabling researchers to accurately track the metabolism of fatty acids in biological systems. Its applications extend to lipid metabolism research, providing insights into fatty acid synthesis and degradation pathways. -
Stable Isotope
Methylmalonic acid-d3 is a stable isotope-labeled form of Methylmalonic acid that serves as an important biomarker for assessing Vitamin B-12 deficiency, particularly in cancer research. Its deuterium labeling provides enhanced sensitivity in analytical techniques such as mass spectrometry. This compound is essential for studies investigating the metabolic pathways associated with vitamin deficiencies and their implications in oncology. -
Stable Isotope
Cholestenone-d5 is a deuterium-labeled analog of Cholestenone, a key metabolite that serves as an intermediate in cholesterol oxidation, predominantly occurring in the liver. This compound plays a significant role in membrane dynamics, influencing cholesterol translocation and efflux processes. Cholestenone-d5 is ideal for studies exploring cholesterol metabolism and its potential long-term effects on cellular function. -
Stable Isotope
Estrone-d4 is a deuterated form of estrone, a naturally occurring estrogenic hormone. Estrone plays a crucial role in various biological processes as a principal endogenous estrogen, primarily synthesized in adipose tissue from androstenedione through aromatization. Estrone-d4 serves as a stable isotope internal standard in quantifying estrone and related estrogens in biological samples, facilitating research in hormone metabolism, endocrine function, and related health studies. -
Stable Isotope
L-Tyrosine-d2-1 is the deuterium-labeled form of L-Tyrosine, a non-essential amino acid. This compound primarily functions as a stable isotope tracer in metabolic studies. It is utilized in research to investigate amino acid metabolism and neuronal signaling, particularly in relation to the modulation of citrate synthase activity in the posterior cortex. -
Stable Isotope
L-Methionine-15N is a stable isotope-labeled form of L-Methionine, the L-isomer of the essential amino acid Methionine. This compound plays a critical role in human development and serves as a hepatoprotectant, helping to safeguard liver function. L-Methionine-15N is valuable for metabolic research, specifically in studies involving amino acid metabolism and tracer applications in vivo. -
Stable Isotope
Desmosterol-d6 is a deuterium-labeled derivative of desmosterol. As a stable isotope, it serves as a valuable tool in tracing and studying cholesterol biosynthesis, specifically in the Bloch pathway where it acts as the immediate precursor to cholesterol. This compound is utilized in metabolic studies to provide insights into cholesterol metabolism and its regulatory mechanisms in various biological systems. -
Stable Isotope
Palmitoleic acid-d13 is a deuterium-labeled derivative of palmitoleic acid, which serves as a stable isotope in biological research. Palmitoleic acid is a monounsaturated fatty acid that has been shown to play a role in preventing cerebrovascular disorders, particularly in hypertensive rat models. This reagent is useful in studies investigating lipid metabolism, cellular signaling, and the physiological effects of fatty acids in various biological contexts. -
Stable Isotope
Aminoadipic acid-d3 is a deuterated form of aminoadipic acid, serving as a stable isotope for metabolic studies. It plays a critical role as an intermediate in lysine metabolism and the biosynthesis of saccharopine. This reagent is valuable in tracer studies, allowing researchers to investigate metabolic pathways and quantify metabolic flux in various biological systems. -
Stable Isotope
Choline-d13 chloride is a stable isotope-labeled form of choline chloride, an organic compound and quaternary ammonium salt. As a substrate for choline acetyltransferase, it plays a crucial role in acetylcholine synthesis. This reagent is valuable for research applications involving metabolic studies, tracer experiments in biological systems, and the investigation of choline's role in growth and development. -
Stable Isotope
2'-Deoxyguanosine-13C10 is a stable isotope-labeled derivative of 2'-Deoxyguanosine, specifically enriched with ten carbon-13 isotopes. This compound serves as a valuable internal standard for quantitative mass spectrometry and NMR studies, aiding in the investigation of nucleoside metabolism and biochemical pathways involving deoxyribonucleic acid (DNA) synthesis. Its application in tracer studies provides insights into cellular processes and molecular interactions in various biological systems. -
Stable Isotope
Hydrocinnamic acid-d9 is the deuterated form of hydrocinnamic acid, acting primarily as a stable isotope. This compound facilitates the study of hydrocinnamic acid's growth regulatory activities in rhizospheric environments, allowing for enhanced tracking and analysis in metabolic and plant growth research. Its unique isotopic labeling enables accurate quantification and tracing in various biological assays. -
Stable Isotope
5-Aminolevulinic acid-13C2,15N hydrochloride is a stable isotope-labeled form of 5-Aminolevulinic acid (5-ALA) featuring isotopes of carbon and nitrogen. This compound is primarily utilized in metabolic studies and tracer experiments to investigate biological processes involving heme biosynthesis. Its unique isotopic labeling makes it valuable for enhancing the precision of metabolic flux analysis and other research applications in biochemistry and molecular biology. -
Stable Isotope
Creatine-d3 hydrate is a stable isotope labeled form of creatine hydrate that serves as a vital component in energy metabolism in muscle and brain cells. This deuterium-labeled compound is essential for tracer studies, allowing researchers to investigate metabolic pathways and energy dynamics under various physiological and pathological conditions. Its application extends to studying muscle physiology and neuroenergetics, contributing significantly to the understanding of metabolic disorders. -
Stable Isotope
L-Proline-15N is a stable isotope-labeled form of the amino acid L-Proline, integrating a nitrogen-15 isotope. This compound serves as a crucial building block in protein synthesis and is widely utilized in metabolic studies and protein characterization. L-Proline-15N enables researchers to investigate amino acid metabolism and protein interactions using isotope labeling techniques, enhancing insights into biological processes. -
Stable Isotope
L-Methionine-34S is a stable isotope-labeled form of L-Methionine, specifically incorporating the sulfur-34 isotope. As an essential amino acid, L-Methionine plays a critical role in various biological processes, including protein synthesis and metabolic regulation. This compound is utilized in isotopic labeling studies, helping to trace metabolic pathways and investigate amino acid metabolism in both cellular and whole organism models. Its hepatoprotective properties further underscore its importance in research related to liver function and detoxification processes. -
Stable Isotope
3-Indoleacetic acid-2,2-d2 is a stable isotope-labeled derivative of 3-Indoleacetic acid, a key auxin that functions as a natural plant growth hormone. This compound is utilized to investigate plant cell elongation and division in various research applications. Its deuterium labeling allows for enhanced tracking and analysis in metabolic studies and experiments involving hormone signaling pathways. -
Stable Isotope
C16-Ceramide-d9 is a deuterium-labeled analogue of C16-Ceramide, serving as a stable isotope for biochemical studies. This compound is essential for investigating sphingolipid metabolism and signaling pathways, including apoptosis and cell growth regulation. C16-Ceramide-d9 is utilized in mass spectrometry and tracer studies to enhance the understanding of lipid biology and cellular processes. -
Stable Isotope
2-Hydroxyisobutyric acid-d6 is a deuterated form of 2-Hydroxyisobutyric acid, serving as a stable isotope for metabolic studies. This compound is an endogenous metabolite that plays a role in cellular energy metabolism and has been implicated in various biochemical pathways. Its unique isotopic labeling facilitates detailed investigations into metabolic flux and labeling experiments in biological systems. Researchers can utilize 2-Hydroxyisobutyric acid-d6 for studies in metabolic disease, bioenergetics, and related fields. -
Stable Isotope
Fumaric acid-d2 is a deuterated form of fumaric acid, serving as a stable isotope label for metabolic studies. This compound is implicated in fumarase deficiency and functions as an oncometabolite, which is associated with cancer pathogenesis. Fumaric acid-d2 is valuable for research applications involving metabolic profiling and the study of cancer metabolism. -
Stable Isotope
L-Cysteine-15N is a stable isotope-labeled form of L-Cysteine, a conditionally essential amino acid. This compound serves as a precursor for key biological molecules, including hydrogen sulfide (H2S), glutathione, and taurine. L-Cysteine-15N is utilized in research to investigate metabolic pathways and the modulation of appetite, as it has been shown to suppress ghrelin levels in various biological systems. -
Stable Isotope
Neopterin-13C5 is a stable isotope-labeled form of neopterin, specifically deuterium-labeled D-(+)-neopterin. As a catabolic product of guanosine triphosphate (GTP), neopterin serves as a significant biomarker for cellular immune system activation. This compound is valuable for research applications involving immunological responses, biochemistry, and metabolic pathways, facilitating deeper insights into immune system dynamics. -
Stable Isotope
Bisphenol A-d6 is the deuterated form of Bisphenol A, a synthetic phenolic compound primarily utilized in the manufacturing of polycarbonate plastics and epoxy resins. This stable isotope is valuable for studying the compound's metabolic pathways and environmental fate due to its role as an endocrine-disrupting compound (EDC). Research indicates that Bisphenol A is linked to various health issues, including reproductive disorders, cardiovascular diseases, diabetes, and obesity, making it a critical target for toxicological studies and environmental assessments. -
Stable Isotope
L-Threonine-d5 is a stable isotope-labeled form of the amino acid L-Threonine. This compound serves as a valuable tracer in metabolic studies, allowing for precise quantification and tracking of L-Threonine in biological systems. It is widely utilized in research applications related to nutritional studies, amino acid metabolism, and microbial fermentation processes. -
Stable Isotope
Levoglucosan-d7 is a deuterium-labeled derivative of levoglucosan, a 1,6-anhydro-β-D-glucopyranose produced through the pyrolysis of glucans. This stable isotope is utilized in environmental research, particularly in studies examining biomass combustion and its byproducts. Levoglucosan-d7 serves as a useful tracer for investigating atmospheric processes and biogeochemical cycling related to organic matter. -
Stable Isotope
Myristic acid-d3 is a deuterium-labeled derivative of myristic acid, a saturated 14-carbon fatty acid found in various animal and vegetable fats, notably in butterfat, coconut oil, palm oil, and nutmeg oil. As a stable isotope reagent, myristic acid-d3 is utilized in metabolic studies and tracer experiments to investigate fatty acid metabolism and lipid profiles. It is essential for research involving lipid biochemistry and tracing metabolic pathways in biological systems. -
Stable Isotope
DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is a stable isotope-labeled form of DL-Homocystine, featuring deuterium substitution at specific positions. DL-Homocystine, a dimeric form of homocysteine, plays a significant role in the study of neurobiological conditions, particularly in relation to the pathogenesis and pathophysiology of schizophrenia. This reagent is valuable for research applications involving metabolic tracking and biochemical analysis of sulfur-containing amino acids, facilitating insights into neural dysfunction and related disorders. -
Stable Isotope
Methylmalonic acid-13C4 is a stable isotope-labeled form of Methylmalonic acid, useful for tracing metabolic pathways. This compound serves as a biomarker for Vitamin B-12 deficiency, particularly relevant in cancer research. It aids in evaluating metabolic disruptions associated with deficiencies and can be utilized in studies involving metabolic profiling and nutritional assessment. -
Stable Isotope
Pyridoxine-d2 hydrochloride is a deuterium-labeled derivative of Pyridoxine hydrochloride, a compound belonging to the pyridine class. This stable isotope serves as an invaluable tool in metabolic studies and tracer experiments. Pyridoxine (Vitamin B6) demonstrates antioxidant properties in cellular models of Alzheimer's disease, primarily through the Nrf-2/HO-1 signaling pathway, making it relevant for research into neurodegenerative disorders. -
Stable Isotope
Estradiol-d3 is a deuterium-labeled analog of the steroid sex hormone estradiol. This stable isotope is essential for studying estradiol's role in fertility and secondary sexual characteristics in females. Estradiol-d3 is commonly used in research to investigate IL-6 expression regulation via the estrogen receptor β (ERβ) pathway, providing valuable insights into hormonal signaling and related biological processes. -
Stable Isotope
D-Ribose (mixture of isomers)-13C5 is a stable isotope-labeled form of D-Ribose, which serves as a crucial sugar moiety in adenosine triphosphate (ATP) production. It functions as an energy enhancer and is commonly employed in metabolic therapy for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Additionally, D-Ribose is involved in protein glycation and can stimulate NF-κB-dependent inflammation through the receptor for advanced glycation end-products (RAGE). This makes it a valuable tool for research in metabolic and inflammatory pathways. -
Stable Isotope
C16-Ceramide-d31 is a deuterated form of C16-Ceramide, functioning as a stable isotope. This compound is essential for studying ceramide metabolism and signaling pathways in biological systems. Its stable isotope labeling enables precise tracking and quantification in mass spectrometry applications, making it valuable for research on lipid biology, cell signaling, and neurobiology. -
Stable Isotope
Isovaleric acid-d7 is a deuterated form of isovaleric acid, functioning as a stable isotope for tracers in metabolic studies. It is recognized for its role in various biological processes and has been associated with neonatal health concerns and Jamaican vomiting sickness in humans. This reagent is valuable in analytical research, particularly in studies involving fatty acid metabolism and its physiological impacts. -
Stable Isotope
Docosahexaenoic acid-d5 is a deuterium-labeled derivative of docosahexaenoic acid (DHA), an omega-3 fatty acid primarily found in brain and retinal tissues. This stable isotope is useful in metabolic studies and tracer experiments, allowing for the investigation of lipid metabolism and the role of DHA in neurological health. Its application extends to research on dietary impacts and fatty acid supplementation in various biological systems. -
Stable Isotope
D-Sorbitol-d8 is a deuterium-labeled derivative of D-Sorbitol, a six-carbon sugar alcohol. This stable isotope is utilized in various research applications, particularly in metabolic studies and tracer experiments. D-Sorbitol serves as a sweetener, humectant, and thickening agent, making it valuable as an excipient and dietary supplement in pharmaceutical formulations. Its deuterium labeling enhances the understanding of biological pathways and kinetics in chemical research. -
Stable Isotope
Cholesterol-d4 is a deuterium-labeled analog of cholesterol, which serves as a stable isotope. Cholesterol is a critical structural component of mammalian plasma membranes, constituting 20-25% of their composition. It significantly influences membrane fluidity and permeability, impacting the functionality of transporters and signaling proteins. Additionally, cholesterol acts as an endogenous agonist for the estrogen-related receptor α (ERRα), making Cholesterol-d4 a valuable tool in research focusing on membrane dynamics and receptor interactions. -
Stable Isotope
L-Tyrosine-15N is a stable isotope-labeled form of L-Tyrosine, a non-essential amino acid. It serves as a valuable tool for metabolic studies and tracer experiments due to its incorporation into proteins and other biomolecules. Its unique isotopic signature allows for the investigation of amino acid metabolism and its effects on various biological processes, making it essential for research in neurobiology and metabolic pathways. -
Stable Isotope
L-Methionine-d8 is a deuterated form of the essential amino acid L-Methionine, which plays a crucial role in human development and liver protection. This stable isotope is valuable in metabolic studies, allowing for more accurate tracking of amino acid metabolism in various biological systems. L-Methionine-d8 can be utilized in research involving nutritional sciences, pharmacology, and toxicology to better understand the dynamics of methionine in physiological processes. -
Stable Isotope
L-Alanine-15N is the isotopically labeled form of L-Alanine, incorporating the stable isotope nitrogen-15. As a non-essential amino acid, L-Alanine plays a crucial role in metabolic processes, contributing to energy production in muscle tissue, the brain, and the central nervous system. This reagent is valuable for research applications in metabolic studies and tracer experiments, facilitating the investigation of amino acid metabolism and its effects on cellular functions and immunity. -
Stable Isotope
Heptadecanoic acid-d3 is a deuterium-labeled derivative of heptadecanoic acid, an odd-chain saturated fatty acid. This compound serves as a stable isotope marker, facilitating studies on lipid metabolism and fatty acid profiling. Research indicates a correlation between heptadecanoic acid levels and metabolic disorders, including coronary heart disease, prediabetes, type 2 diabetes, and multiple sclerosis, making it valuable for investigating disease mechanisms and potential therapeutic targets. -
Stable Isotope
L-Aspartic acid-13C4,15N is a stable isotope-labeled form of L-Aspartic acid, featuring both carbon-13 and nitrogen-15 isotopes. This amino acid is capable of penetrating the blood-brain barrier and is often utilized in the development of prodrugs aimed at colon and cecal tissues. L-Aspartic acid also plays a significant role in the investigation of inflammatory conditions, serving as a valuable tool in metabolic and biochemical research. -
Stable Isotope
Creatine-13C is a stable isotope-labeled form of creatine, an endogenous derivative of amino acids. It is integral to cellular energy metabolism, particularly in muscle and brain tissues. This reagent is widely used in metabolic studies, tracer experiments, and research focusing on energy dynamics and muscle physiology. -
Stable Isotope
5-Hydroxyindole-3-acetic acid-d2 is a deuterium-labeled form of 5-hydroxyindole-3-acetic acid, a key metabolite of serotonin. This stable isotope is utilized in research to accurately quantify serotonin metabolism and assess neuroendocrine tumor markers. Its unique labeling allows for advanced analytical techniques, making it valuable in biochemical and pharmacological studies. -
Stable Isotope
Tetranor-PGEM-d6 is a deuterated stable isotope derivative of tetranor-PGEM, designed for use in mass spectrometry and biochemical studies. This compound provides researchers with a valuable tool for the quantitative analysis of prostaglandin metabolites and their pathways. Its incorporation of deuterium allows for enhanced sensitivity and specificity in tracking metabolic processes, making it an essential reagent for studies involving lipid signaling and inflammation research.
