Catalog No.
Product Name
Application
Product Information
Citations
-
Stable Isotope
Raloxifene-d10-1 is a deuterium-labeled derivative of Raloxifene, a selective estrogen receptor modulator (SERM) derived from benzothiophene. It exhibits estrogen-agonistic activity on bone and lipid metabolism while antagonizing estrogen receptors in breast and uterine tissues. This compound is crucial for research involving breast cancer and osteoporosis, facilitating studies on the pharmacokinetics and pharmacodynamics of Raloxifene and its effects in various biological contexts. -
Stable Isotope
Clomiphene-d5 citrate is a deuterium-labeled form of Enclomiphene citrate, a potent oral estrogen receptor antagonist. Its antioestrogenic properties make it valuable for studying estrogen signaling pathways and reproductive health. This stable isotope is an essential tool for biochemical research that requires precise tracking of metabolic pathways and pharmacokinetics involving Clomiphene. -
Stable Isotope
Norethindrone-d6 is a deuterated form of Norethindrone, a progestin used clinically for managing conditions such as endometriosis, abnormal uterine bleeding, and secondary amenorrhea. As a stable isotope, Norethindrone-d6 serves as a valuable tool in metabolic studies and tracing applications. This compound features an alkyne functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing compounds, facilitating the synthesis of complex bioconjugates and polymers in chemical research. -
Stable Isotope
Norgestrel-d6 is a deuterium-labeled derivative of Levonorgestrel, a synthetic progestogen commonly utilized in hormonal contraceptives. This compound serves as a stable isotope and is a valuable click chemistry reagent featuring an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Its applications span various biochemical research fields, enhancing the investigation of metabolic pathways and drug interactions. -
Stable Isotope
Medroxyprogesterone-d3 is a deuterium-labeled derivative of Medroxyprogesterone, a synthetic progestin and a potent agonist of the progesterone receptor. This stable isotope is utilized in various research applications, including pharmacokinetic studies, hormonal regulation investigations, and the development of analytical methods for progesterone-related compounds. Its use enhances the understanding of progestin interactions and metabolism in biological systems. -
Stable Isotope
Drospirenone-d4 is the deuterated form of Drospirenone, a synthetic progestin structurally related to spironolactone. This stable isotope is utilized primarily in pharmacokinetic studies and metabolic research to trace drug activity in biological systems. Its deuterium labeling allows for enhanced detection and quantification in complex biological matrices. -
Stable Isotope
Gestodene-d6 is a deuterium-labeled derivative of the progestogen hormonal contraceptive, Gestodene. This stable isotope serves as a valuable tool in click chemistry applications, featuring an alkyne functionality that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties make it suitable for various biochemical research applications, including metabolic labeling, drug development, and tracking biological processes. -
Stable Isotope
Norgestimate-d6 is a deuterium-labeled form of Norgestimate, a synthetic progestin that exhibits selective progestational activity with minimal androgenic effects. It is utilized primarily in oral contraceptive formulations. Norgestimate-d6 serves as a valuable tool in click chemistry applications, containing an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating the synthesis of complex bioconjugates for chemical biology research. -
Stable Isotope
Methimazole-d3 is a deuterium-labeled derivative of Methimazole, an anti-thyroid agent that inhibits thyroid hormone synthesis in the thyroid gland. This stable isotope is valuable for biochemical studies, including pharmacokinetic and metabolic research. Methimazole has also been associated with hepatotoxicity, making Methimazole-d3 an important tool for studying its effects and mechanisms in metabolic processes. -
Stable Isotope
Liothyronine-13C6-1 is a stable isotope-labeled form of Liothyronine, which serves as a potent agonist for thyroid hormone receptors TRα and TRβ, exhibiting inhibition constants (Kis) of 2.33 nM for both receptors. This reagent is valuable for research applications involving thyroid hormone signaling, metabolic studies, and metabolic disorders. Its isotopic labeling allows for enhanced tracking and quantification in various analytical techniques, facilitating investigations into hormone receptor activity and related biological pathways. -
Stable Isotope
Reverse T3-13C6 hydrochloride is a stable isotope-labeled form of Reverse T3, featuring six carbon-13 isotopes. This compound is primarily utilized in metabolic studies and tracer experiments, allowing for the quantification and analysis of thyroid hormone metabolism. Its stable isotope labeling enhances sensitivity and accuracy in various biological and biochemical research applications. -
Stable Isotope
Paricalcitol-d6 is a deuterium-labeled form of Paricalcitol, targeting the modulation of parathyroid hormone secretion. It is utilized in the prevention and treatment of secondary hyperparathyroidism, particularly in patients with chronic renal failure. Paricalcitol-d6 serves as a valuable stable isotope for research applications focusing on metabolic studies and pharmacokinetics of calcimimetics in kidney disease. -
Stable Isotope
Difethialone-d4 is a deuterium-labeled analogue of the anticoagulant rodenticide difethialone. This compound inhibits vitamin K metabolism in the liver, leading to impaired synthesis of coagulation factors and resulting in bleeding disorders in rodent populations. Difethialone-d4 is utilized in research to investigate the ecological effects of rodenticide applications and to study the pharmacokinetics and dynamics of difethialone in various biological systems. -
Stable Isotope
Coumachlor-d4 is a deuterium-labeled form of Coumachlor, a vitamin K antagonist known for its oral anticoagulant properties. This stable isotope is valuable for tracking and quantifying Coumachlor in metabolic studies and pharmacokinetic research. It is utilized in studies investigating the mechanisms of action of anticoagulants and their effects on coagulation pathways. -
Stable Isotope
Phenprocoumon-d5 is a deuterated version of Phenprocoumon, a coumarin derivative that functions as a long-acting oral anticoagulant and vitamin K antagonist. This stable isotope is valuable for pharmacokinetic studies and metabolic research, enabling precise tracking of compound behavior in biological systems. Its deuterium labeling supports advanced analytical techniques, making it an essential tool for researchers focusing on anticoagulant therapy and coagulation studies. -
Stable Isotope
(1S)-Calcitriol-d6 is a stable isotope-labeled form of (1S)-Calcitriol, also known as 1α,25-Dihydroxy-3-epi-vitamin D3-d6. This compound primarily targets the vitamin D receptor (VDR), exhibiting significant biological activities, including the inhibition of keratinocyte proliferation and the suppression of parathyroid hormone secretion. It is suitable for various research applications, particularly in studies related to vitamin D metabolism and its physiological effects. -
Stable Isotope
(1S)-Calcitriol-d3 is a deuterated form of (1S)-Calcitriol, a natural metabolite of 1α,25-dihydroxyvitamin D3. This stable isotope serves as a valuable tool for tracing and quantifying vitamin D metabolism and interactions. (1S)-Calcitriol-d3 exhibits significant biological activity through its potent engagement with the vitamin D receptor (VDR), promoting the inhibition of keratinocyte proliferation and the suppression of parathyroid hormone secretion. It is ideally suited for research applications in endocrinology, dermatology, and metabolic studies related to vitamin D signaling. -
Stable Isotope
Fmoc-Gly-OH-d2 is a deuterium-labeled derivative of Fmoc-protected glycine, serving as a stable isotope in chemical research. It plays a crucial role in synthetic chemistry, particularly in the preparation of peptide and other complex compounds. This reagent is particularly useful for studies involving mass spectrometry and tracking the dynamics of biological processes. -
Stable Isotope
N-Valerylglycine-d2 is a deuterated analog of N-Valerylglycine, serving as a stable isotope in scientific research. This compound, a derivative of glycine, is primarily utilized in metabolic studies and isotopic labeling experiments. Its unique properties enable enhanced tracking of biochemical pathways and facilitate the investigation of various physiological processes. -
Stable Isotope
Fmoc-L-Val-OH-d8 is a deuterium-labeled derivative of Fmoc-L-Val-OH, serving as a stable isotope for research applications. This compound is utilized primarily in the synthesis of protected amino acids, which are essential for peptide chemistry. Its stable isotopic labeling facilitates detailed characterization of peptides and proteins in various analytical studies, including mass spectrometry and NMR spectroscopy. -
Stable Isotope
N-Heptanoylglycine-d2 is a stable isotope-labeled derivative of N-Heptanoylglycine. This compound serves as a valuable tool in metabolic studies and isotopic tracing applications, allowing for enhanced understanding of glycine metabolism. Its incorporation of deuterium enables precise tracking in various biological systems, facilitating research in neuropharmacology and other fields focused on amino acid derivatives. -
Stable Isotope
Fmoc-Gly-OH-15N is a stable isotope-labeled derivative of Fmoc-glycine, featuring nitrogen-15 (15N) isotopes. This compound serves as a tool for the synthesis of peptide and protein constructs, particularly in studies requiring isotopic labeling. Its use in research facilitates the investigation of protein dynamics and interactions through NMR spectroscopy and other analytical techniques. -
Stable Isotope
Fmoc-Gly-OH-13C2,15N is a stable isotope-labeled derivative of Fmoc-protected glycine, incorporating both 15N and 13C isotopes. This compound serves as a valuable building block for the synthesis of various biomolecules, facilitating studies in peptide chemistry and other biochemical research applications. Its isotopic labeling enables precise tracking and analysis in metabolic studies and NMR investigations. -
Stable Isotope
N-Valerylglycine-13C2,15N is a stable isotope-labeled derivative of N-Valerylglycine, containing two carbon-13 and one nitrogen-15 isotope. This compound serves as a valuable tool in metabolic studies and tracer experiments, enabling precise quantification and tracking of metabolic pathways. It is particularly useful in proteomics and applications involving stable isotope labeling for cellular metabolism analysis. -
Stable Isotope
Alitame-d3 is a deuterium-labeled derivative of Alitame, a high-intensity sweetener synthesized from L-aspartic acid, D-alanine, and a thietane-derived amine. This stable isotope serves as an invaluable tool in metabolic studies and tracer experiments, facilitating the investigation of sweetener metabolism and its impact on biological systems. Researchers can utilize Alitame-d3 for precise quantitative analysis in various applications, including nutrition and pharmacokinetics. -
Stable Isotope
Fmoc-Gly-OH-13C is a stable isotope-labeled derivative of Fmoc-glycine, specifically incorporating 13C. This reagent serves as a versatile building block in peptide synthesis, providing a means to incorporate stable isotopes for mechanistic studies and metabolic tracking in biological research. Its applications extend to isotopic labeling experiments, aiding in the elucidation of metabolic pathways and protein dynamics. -
Stable Isotope
Fmoc-Gly-OH-2-13C,15N is a stable isotope-labeled derivative of Fmoc-protected glycine, specifically enriched with 13C and 15N. This compound is essential for studies involving peptide synthesis and can be utilized in various biochemical applications, including NMR spectroscopy and mass spectrometry. Its stable isotopic labeling enhances the detection and quantification of glycine in complex mixtures, making it a valuable tool in metabolic and structural biology research. -
Stable Isotope
N-Formylglycine ethyl ester-13C2 is a stable isotope-labeled derivative of N-Formylglycine ethyl ester. This compound serves as a valuable tool in metabolic studies and tracer experiments, enabling researchers to investigate glycine metabolism and enzymatic processes involving this amino acid. Its isotopic labeling allows for enhanced analytical sensitivity and specificity in various biological applications, making it an essential reagent for studies in biochemistry and cellular biology. -
Stable Isotope
DL-Phenylmercapturic Acid-13C6 is a stable isotope-labeled analog of DL-Phenylmercapturic Acid, also known as N-Acetyl-S-phenyl-L-cysteine-13C6. This cysteine derivative is useful for metabolic studies as it allows the tracing of sulfur-containing compounds in biological systems. Its applications include pharmacokinetics, toxicology research, and exploring mechanisms of drug metabolism. -
Stable Isotope
Boc-D-Chg-OH-d11 is a deuterated form of Boc-D-Chg-OH, functioning as a stable isotope-labeled compound. This derivative of glycine is valuable in various biochemical applications, particularly in studies involving metabolic pathways and tracer kinetics. Its labeling with deuterium enhances tracking capabilities in mass spectrometry and NMR experiments, supporting advanced research in chemical biology and proteomics. -
Stable Isotope
H-N-Me-Ala-OH-13C,d3 is a stable isotope-labeled derivative of N-Methyl-L-alanine. This compound features both deuterium and carbon-13 isotopes, making it valuable for precision tracing and quantification in metabolic studies. Its applications include research in amino acid metabolism and protein synthesis, enabling insights into cellular processes and metabolic pathways. -
Stable Isotope
Methyl 2-aminoacetate hydrochloride-13C2,15N is a stable isotope-labeled derivative of Methyl 2-aminoacetate hydrochloride, featuring both carbon-13 and nitrogen-15 isotopes. This compound is primarily utilized in metabolic studies and tracer experiments to investigate amino acid metabolism and biosynthesis pathways. Its isotopic labeling enhances detection and quantification in various analytical techniques, making it a valuable tool for researchers in biochemical and physiological studies. -
Stable Isotope
N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester-13C5,15N is a stable isotope-labeled derivative of N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester. This compound incorporates five carbon-13 and one nitrogen-15 isotopes, making it valuable for metabolic labeling and tracking in biological studies. It is applicable in research involving glutamate signaling pathways and can enhance the understanding of protein dynamics in cellular systems. -
Stable Isotope
Fmoc-Gly-OH-13C2 is a stable isotope-labeled variant of Fmoc-glycine, featuring two carbon-13 isotopes. This Fmoc-protected glycine derivative is essential for the synthesis of various compounds in the pharmaceutical and chemical research domains. Its isotopic labeling facilitates advanced analytical techniques such as NMR spectroscopy and mass spectrometry, enhancing the study of molecular interactions and dynamics. -
Stable Isotope
N-Fmoc-L-isoleucine-d10 is a deuterated derivative of Fmoc-D-Allo-Ile-OH, featuring a stable isotope substitution that enhances its utility in various research applications. This compound serves as a valuable tool for peptide synthesis and isotope labeling studies, enabling detailed analysis of metabolic pathways and protein dynamics. Its stable isotope labeling allows for advanced techniques such as NMR spectroscopy and mass spectrometry in proteomic research. -
Stable Isotope
Fmoc-L-Val-OH-15N is a stable isotope-labeled derivative of Fmoc-L-Valine, where the nitrogen atom is replaced with the non-radioactive isotope 15N. This compound serves as a valuable tool for NMR studies and other applications requiring isotopic labeling. It is particularly useful in protein stability studies, synthesis of labeled peptides, and investigations involving metabolic pathways in cellular systems. -
Stable Isotope
3-Bromo-L-tyrosine-13C9,15N TFA is a stable isotope-labeled derivative of 3-Bromo-L-tyrosine, incorporating both carbon-13 and nitrogen-15 isotopes. This compound serves as a valuable tool for metabolic studies and quantitative analysis in biological research, enabling the tracing of metabolic pathways and the investigation of tyrosine metabolism. Its unique isotopic labeling facilitates advanced techniques such as mass spectrometry and NMR, allowing for precise measurements in biochemical applications. -
Stable Isotope
Ac-D-Ala-OH-d3 is a deuterium-labeled derivative of Ac-D-Ala-OH, specifically designed for stable isotope applications in biochemical research. This compound serves as a valuable tracer in studies of metabolism, protein interactions, and peptide synthesis. Its unique isotopic composition allows for enhanced detection and differentiation in various analytical techniques, making it an essential tool for researchers investigating alanine-related pathways and mechanisms. -
Stable Isotope
H-Gly-OBzl.TosOH-13C2,15N is a stable isotope-labeled derivative of H-Gly-OBzl.TosOH, incorporating both carbon-13 and nitrogen-15 isotopes. This compound is primarily employed in studies requiring the tracking of glycine-related pathways through stable isotope labeling. Its applications include metabolic studies, tracer experiments, and other biochemical research where precise isotopic composition is essential for accurate data interpretation. -
Stable Isotope
Fmoc-Gly-OH-1-13C is a stable isotope-labeled derivative of Fmoc-protected glycine. This compound is essential for applications in peptide synthesis and protein labeling, facilitating the study of biochemical pathways and interactions involving glycine. The incorporation of the 13C isotope allows for advanced NMR spectroscopy analyses, aiding researchers in elucidating molecular structures and dynamics. -
Stable Isotope
Fmoc-Trp(Boc)-OH-13C11,15N2 is a stable isotope-labeled derivative of Fmoc-Trp(Boc)-OH, incorporating 13C and 15N isotopes. This compound exhibits self-assembly properties, forming stable, pH-responsive spherical nanoparticles capable of efficiently loading and releasing bioactive molecules. Its excellent biocompatibility and high cell uptake rate make Fmoc-Trp(Boc)-OH-13C11,15N2 suitable for research applications in drug delivery systems and nanomedicine. -
Stable Isotope
H-Phe-OMe.hydrochloride-d5 is a deuterium-labeled derivative of H-Phe-OMe.hydrochloride, primarily utilized as a stable isotope. This compound is valuable in studies involving protein labeling and metabolic tracing, allowing for enhanced analytical precision in research involving phenylalanine and its analogs. Its application extends to various fields, including biochemistry, pharmacology, and metabolic studies, facilitating a deeper understanding of physiological processes. -
Stable Isotope
Fmoc-L-Lys (Boc)-OH-13C is a stable isotope-labeled derivative of Fmoc-L-Lys (Boc)-OH, targeting lysine residues in peptide synthesis. This compound is primarily utilized in mass spectrometry and isotopic labeling studies, facilitating the investigation of protein dynamics and interactions. Its 13C labeling allows for enhanced tracking and quantification of peptides in biological samples, making it valuable for metabolic studies and proteomics research. -
Stable Isotope
Fmoc-Thr(tBu)-OH-15N is a stable isotope-labeled derivative of threonine, specifically the Fmoc-protected t-butyl ether form. This reagent provides a means for incorporating 15N into peptide synthesis, enabling the study of protein interactions and dynamics using techniques such as nuclear magnetic resonance (NMR) spectroscopy. Its use in research facilitates the investigation of metabolic pathways and provides insights into nitrogen tracking in biological systems. -
Stable Isotope
Tiglyl Glycine-13C215N is a stable isotope-labeled derivative of (E)-2-(2-Methylbut-2-enamido)acetic acid, featuring carbon-13 and nitrogen-15 isotopes. This compound serves as a valuable tool in metabolic studies, providing insights into amino acid metabolism and the kinetic tracking of glycine derivatives in biological systems. Its unique isotopic labeling makes it suitable for applications in NMR spectroscopy and mass spectrometry for detailed analysis of metabolic pathways. -
Stable Isotope
Fmoc-Arg(Pbf)-OH-13C6,15N4 is a stable isotope-labeled derivative of Fmoc-Arg(Pbf)-OH, incorporating both 13C and 15N isotopes. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), facilitating the incorporation of arginine residues into peptide sequences. The inclusion of Fmoc as an amine protecting group enhances the compound's utility in synthesizing complex peptides for various research applications, including structural studies and the development of peptide therapeutics. -
Stable Isotope
Fmoc-L-Val-OH-1-13C is a stable isotope-labeled derivative of Fmoc-L-Valine, specifically incorporating a carbon-13 isotope. This reagent serves as a valuable tool in studies involving metabolic profiling, tracer studies, and NMR spectroscopy. Its application is particularly useful in elucidating metabolic pathways and understanding the roles of valine in biological systems. -
Stable Isotope
3-Bromo-L-tyrosine-13C9 is a stable isotope-labeled analogue of 3-bromo-L-tyrosine, featuring nine carbon-13 isotopes. This compound is primarily used in metabolic studies and tracer experiments, facilitating the investigation of tyrosine metabolism and its role in biological processes. Its isotopic labeling is crucial for quantitative analysis in various biomedical research applications. -
Stable Isotope
Timonacic-d4 is a deuterium-labeled derivative of Timonacic (1,3-Thiazolidine-4-carboxylic acid), a thiol antioxidant. It exhibits significant anti-aging and anti-hepatotoxic properties, making it a valuable tool for investigating liver diseases and acute illnesses. Additionally, Timonacic-d4 is utilized in research focused on cancer, enabling studies into its potential effects on disease reversal mechanisms. -
Stable Isotope
Fmoc-Asp(OtBu)-OH-15N is a 15N-labeled derivative of Fmoc-Asp(OtBu). This compound features an Fmoc-protected L-aspartate with a 4-tert-butyl protecting group, making it particularly useful in peptide synthesis. The incorporation of stable isotopes allows for advanced applications in mass spectrometry and tracking dynamic processes in biological research. Fmoc-Asp(OtBu)-OH-15N serves as a valuable tool for studying peptide structure and function in various biochemical contexts.
