Biological Activity
Kaempferol is found to inhibit bovine aorta myosin light chain kinase with a Ki of 0.3-0.5 microM and also is found to inhibit VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway.
In vitro | DMSO | Warmed: 53 mg/mL (185.17 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (10.48 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.94 mL | 174.7 mL | 349.41 mL |
0.5 mM | 6.99 mL | 34.94 mL | 69.88 mL |
1 mM | 3.49 mL | 17.47 mL | 34.94 mL |
5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10495 |
---|---|
Actions | Inhibitor, Agonist |
CAS No. | 520-18-3 |
Formula | C15H10O6 |
M. Wt | 286.2 |
Solubility | DMSO |
Purity | >98% |
SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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