L-685458

Catalog No.: A15899

γ-secretase inhibitor

L-685458 Chemical Structure

CAS NO. 292632-98-5

L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $150.00

Special Price $120.00

2 mg

Regular Price: $220.00

Special Price $176.00

5 mg

Regular Price: $475.00

Special Price $380.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
Targets
Gamma-secretase
17 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.86 mL 74.31 mL 148.62 mL
0.5 mM 2.97 mL 14.86 mL 29.72 mL
1 mM 1.49 mL 7.43 mL 14.86 mL
5 mM 0.3 mL 1.49 mL 2.97 mL

*The above data is based on the productmolecular weight 672.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15899
Actions Inhibitor
M. Wt 672.85
Formula C39H52N4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 292632-98-5
Synonyms L685458, L 685458, L685,458
SMILES O=C(OC(C)(C)C)N[[email protected]]([[email protected]](O)C[[email protected]@H](CC1=CC=CC=C1)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC2=CC=CC=C2)C(N)=O)=O)=O)CC3=CC=CC=C3

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