Lopinavir (ABT-378)

Catalog No.: A10537

HIV Protease inhibitor

Lopinavir (ABT-378) Chemical Structure

CAS NO. 192725-17-0

Lopinavir is an inhibitor of the HIV protease.

Availability: In stock

Package Price Qty
10 mg
$30.00
100 mg
$80.00
200 mg
$150.00
10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Lopinavir is an inhibitor of the HIV protease.
Targets
HIV protease (Cell-free assay)
1.3 pM(Ki)
In vitro (25°C) DMSO 126 mg/mL (200.38 mM)
Water <1 mg/mL (<1 mM)
Ethanol 126 mg/mL (200.38 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.9 mL 79.52 mL 159.03 mL
0.5 mM 3.18 mL 15.9 mL 31.81 mL
1 mM 1.59 mL 7.95 mL 15.9 mL
5 mM 0.32 mL 1.59 mL 3.18 mL

*The above data is based on the productmolecular weight 628.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10537
Actions Inhibitor
M. Wt 628.8
Formula C37H48N4O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 192725-17-0
Synonyms ABT-378
SMILES CC1=C(C(=CC=C1)C)OCC(=O)N[[email protected]@H](CC2=CC=CC=C2)[[email protected]](C[[email protected]](CC3=CC=CC=C3)NC(=O)[[email protected]](C(C)C)N4CCCNC4=O)O

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