LpxH-IN-AZ1 is a sulfonyl piperazine compound that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). This compound demonstrates significant inhibitory activity against Klebsiella pneumoniae LpxH, achieving an IC50 value of 0.36 μM. LpxH-IN-AZ1 is valuable for research applications targeting antibiotic drug development and bacterial resistance mechanisms.
LpxH-IN-AZ1 is a sulfonyl piperazine compound that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). This compound demonstrates significant inhibitory activity against Klebsiella pneumoniae LpxH, achieving an IC50 value of 0.36 μM. LpxH-IN-AZ1 is valuable for research applications targeting antibiotic drug development and bacterial resistance mechanisms.
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