Luteolin

Catalog No.: A10541

PDE4 inhibitor

Luteolin

Luteolin Chemical Structure

CAS NO. 491-70-3

Luteolin is a PDE4 inhibitor, phosphodiesterase inhibitor, and an interleukin 6 inhibitor, affecting xylazine/ketamine-induced anesthesia in mice. Luteolin acts as a monoamine transporter activator, and is one of the few chemicals demonstrated to possess this property.

Availability: In stock

Package Price Qty
10 mg
$50.00
50 mg
$60.00
200 mg
$150.00
10mM * 1mL in DMSO
$50.00
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Biological Activity

Luteolin is a PDE4 inhibitor, phosphodiesterase inhibitor, and an interleukin 6 inhibitor, affecting xylazine/ketamine-induced anesthesia in mice. Luteolin acts as a monoamine transporter activator, and is one of the few chemicals demonstrated to possess this property.
In vitro DMSO 55 mg/mL (192.14 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (10.48 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.94 mL 174.7 mL 349.41 mL
0.5 mM 6.99 mL 34.94 mL 69.88 mL
1 mM 3.49 mL 17.47 mL 34.94 mL
5 mM 0.7 mL 3.49 mL 6.99 mL

*The above data is based on the productmolecular weight 286.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10541
Actions Inhibitor
CAS No. 491-70-3
Formula C15H10O6
M. Wt 286.2
Solubility DMSO
Purity >98%
Synonyms 3',4',5,7-Tetrahydroxyflavone, Luteoline, Luteolol
SMILES C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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