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Luteolin is a PDE4 inhibitor, phosphodiesterase inhibitor, and an interleukin 6 inhibitor, affecting xylazine/ketamine-induced anesthesia in mice. Luteolin acts as a monoamine transporter activator, and is one of the few chemicals demonstrated to possess this property.
| In vitro | DMSO | 55 mg/mL (192.14 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 3 mg/mL (10.48 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.94 mL | 174.7 mL | 349.41 mL |
| 0.5 mM | 6.99 mL | 34.94 mL | 69.88 mL |
| 1 mM | 3.49 mL | 17.47 mL | 34.94 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10541 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 491-70-3 |
| Formula | C15H10O6 |
| M. Wt | 286.2 |
| Purity | >98% |
| Synonyms | 3',4',5,7-Tetrahydroxyflavone, Luteoline, Luteolol |
| SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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