Methyltetrazine-DBCO is a non-cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This compound features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Additionally, the inclusion of a tetrazine moiety allows for inverse electron demand Diels-Alder reactions (iEDDA) with trans-cyclooctene (TCO) compounds. Methyltetrazine-DBCO is an essential reagent for researchers developing targeted therapies through click chemistry methodologies.
Methyltetrazine-DBCO is a non-cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This compound features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Additionally, the inclusion of a tetrazine moiety allows for inverse electron demand Diels-Alder reactions (iEDDA) with trans-cyclooctene (TCO) compounds. Methyltetrazine-DBCO is an essential reagent for researchers developing targeted therapies through click chemistry methodologies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
