Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Arizonin B1 is an antibiotic compound primarily targeting Gram-positive bacteria. Derived from microbial sources, it exhibits significant antibacterial activity, making it a valuable tool for research in microbial resistance and antibiotic efficacy. Its application extends to studies focusing on the mechanisms of action against pathogenic strains, contributing to the development of new therapeutic strategies. -
Antibiotic
Alahopcin is a dipeptide antibiotic that exerts its activity by inhibiting bacterial protein synthesis. It demonstrates a broad spectrum of antibacterial efficacy, making it useful for research applications in microbiology and infectious disease studies. Its unique mechanism of action allows for exploration of antibiotic resistance and the development of new therapeutic strategies. -
Antibiotic
Phospholine is an antibiotic that targets bacterial growth and proliferation. It demonstrates potent cytotoxic activity, with IC50 values of 3.37 μg/mL for Ll 210 cells, 2.20 μg/mL for P388 cells, and 1.99 μg/mL for EL-4 cells. This compound is applicable in research settings focused on antimicrobial resistance and the development of novel therapeutic strategies. -
Antibiotic
YM-17K is a macrolide antibiotic that targets bacterial cell function. It demonstrates broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as anaerobic bacteria. With stable activity in serum and reduced sensitivity to pH fluctuations, YM-17K is valuable for research applications in microbiology and antibiotic resistance studies. -
Antibiotic
Rubiginone D2 is an antibiotic known for its antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. In addition to its antibacterial properties, Rubiginone D2 demonstrates significant antitumor efficacy, inhibiting the proliferation of various cancer cell lines, including HM02, Kato III, HepG2, and MCF7, with GI50 values of 0.1, 0.7, less than 0.1, and 7.5 μM, respectively. This compound is valuable for research on antibiotic resistance and cancer therapeutics. -
Antibiotic
Amicetin is a potent antibiotic that primarily targets bacterial protein synthesis. Demonstrating significant activity against gram-positive bacteria, Amicetin effectively disrupts cellular processes essential for bacterial growth and replication. This compound is valuable for research applications focused on elucidating antibiotic mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibiotic
Martinomycin is an antibiotic that targets bacterial infections by inhibiting the growth of Staphylococcus spp., Streptococcus spp., and Enterococcus spp. It demonstrates a minimum inhibitory concentration (MIC) range of 0.06 to 0.5 μg/mL, indicating potent antibacterial activity. This compound is valuable in microbiological studies and research focused on antibiotic resistance mechanisms. -
Macrolide Antibiotic
PF-945863 is an orally active macrolide antibiotic that targets bacterial ribosomes, thereby inhibiting protein synthesis. This compound demonstrates significant efficacy against multidrug-resistant respiratory tract bacterial strains, making it a valuable tool for research in combating antibiotic resistance. Its application extends to studies aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. -
Antibiotic
Diastovaricin I, a derivative of naphthomycin, functions primarily as an antibiotic. It is notable for its ability to induce differentiation in mouse Friend cells, making it a valuable tool for studies in cell biology and differentiation processes. Its unique mechanism and biological activity position it as a potential reagent for research involving cellular development and related applications. -
Antibiotic
Cefalonium dihydrate is a cephalosporin antibiotic with a primary action against Staphylococcus aureus. This compound exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent in the study of bacterial infections and inflammation-related research. Cefalonium dihydrate is suitable for applications in microbiology and pharmacology, providing insights into antibiotic efficacy and therapeutic development. -
β-lactam Antibiotic
Mezlocillin is a β-lactam antibiotic with a semisynthetic structure and extended-spectrum activity. It demonstrates efficacy against a wide range of both gram-negative and gram-positive bacteria. Mezlocillin is suitable for research applications focused on bacterial infections and the investigation of antibiotic resistance mechanisms. -
oxazolidinone antibiotic
Posizolid (AZD2563) is an oxazolidinone antibiotic designed for the treatment of bacterial infections. This compound exhibits potent anti-mycobacterial activity, making it a valuable tool in research focused on mycobacterial diseases, including tuberculosis. Its mechanism of action involves inhibition of protein synthesis, targeting the bacterial ribosome. -
Antibiotic
Leucomycin tartrate is a potent 16-membered macrolide antibiotic that primarily targets bacterial protein synthesis. It exhibits strong antibacterial activity against a range of Gram-positive organisms, making it useful in research applications focused on antimicrobial resistance and the mechanisms of action of antibiotics. This compound is instrumental for studies investigating bacterial infections and developing novel therapeutic strategies. -
Antibiotic
Armeniaspirol B is a selective antibiotic that primarily targets Gram-positive pathogens. It exhibits minimal inhibitory concentration (MIC) values of 0.5 μg/mL against Staphylococcus aureus Newman and 2.0 μg/mL against Staphylococcus aureus USA300. This compound is of particular interest for research focused on Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections. -
Antibiotic
TMC-169 is a potent antibiotic belonging to the Aspochalasin group, isolated from Aspergillus flavipes. This compound demonstrates significant anti-tumor activity across various cancer cell types, making it relevant for research into hematologic malignancies, non-small cell lung cancer, breast cancer, and glioma. TMC-169 serves as a valuable tool for exploring therapeutic strategies against these malignancies. -
Bacteriostatic Antibiotic
Trimethoprim sulfate is a potent bacteriostatic antibiotic that functions primarily as a dihydrofolate reductase inhibitor. It exhibits broad-spectrum activity against various Gram-positive and Gram-negative aerobic bacteria, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim sulfate has demonstrated potential in inhibiting Influenza A virus infection in chick embryos when used in combination with zinc, highlighting its multifaceted applications in microbial research. -
Antibiotic/Antimicrobial Peptide
Aurein 2.2 is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria including Staphylococcus aureus and S. epidermidis. Isolated from the skin secretions of L. aurea, Aurein 2.2 demonstrates potential as an effective antibiotic, making it a valuable tool for research in microbiology and antimicrobial therapy. Its unique mechanism of action and efficacy against resistant strains underline its relevance in the study of infection control and antibiotic development. -
Macrolide Antibiotic
Aldgamycin G is a macrolide antibiotic that targets Gram-positive bacteria. Isolated from Streptomyces avidinii, it exhibits significant antibacterial activity, making it a valuable compound for research in microbiology and antibiotic resistance studies. Its mechanism of action involves inhibition of bacterial protein synthesis, enhancing its utility in the investigation of microbial pathogenicity and treatment options against Gram-positive infections. -
Antibiotic
LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development. -
Antibiotic
Daunosamnyl-daunorubicin is an antibiotic that binds to calf thymus DNA, exhibiting significant intercalation properties. This compound is primarily utilized in research focused on anticancer therapies and the study of DNA-drug interactions. Its mechanism of action involves disrupting the normal functioning of DNA, making it valuable for investigations into its therapeutic efficacy against various malignancies. -
Quinolone Antibiotic
Lomefloxacin (aspartate) targets bacterial DNA gyrase, exhibiting potent antibacterial activity as a broad-spectrum quinolone antibiotic. It is effective against a wide range of bacterial pathogens and is utilized in research concerning respiratory tract infections, genitourinary infections, gastrointestinal infections, and ENT infections. Its mechanism of action disrupts bacterial DNA replication, making it a valuable tool for investigating antibiotic resistance and treatment efficacy. -
Antibiotic
Spiramycin (hexanedioate) is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. Its chemical structure features a 16-membered lactone ring with three sugar moieties: mycaminose, forosamine, and mycarose. Spiramycin exhibits significant antibacterial and antiparasitic activity, making it valuable in the study of infectious diseases and potential therapeutic applications. -
Antibiotic
BAL-19403 is a macrolide antibiotic that primarily targets bacterial infections. It demonstrates potent activity against Propionibacterium acnes, specifically against strains resistant to erythromycin and clindamycin. BAL-19403 exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent for research focused on acne treatment and related inflammatory skin conditions. -
Antibiotic
BU-2313 A is an antibiotic that exhibits antimicrobial activity through its unique dienoyltetraamide acid structure. This compound is related to streptolysin and tilamycin, making it a valuable tool for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in combating bacterial infections positions it as a relevant candidate for research in antimicrobial drug development. -
Peptide Antibiotic
Angiotensin III antipeptide is a peptide antibiotic that inhibits the activity of angiotensin II, a key regulator in the renin-angiotensin system. It exhibits biological activity by modulating blood pressure and fluid balance, making it a valuable tool in cardiovascular and renal research. Its applications include studying the effects of angiotensin peptides on physiological processes and exploring potential therapeutic interventions in related diseases. -
Antitumor Antibiotic
Kapurimycin A2 is an antitumor antibiotic derived from the culture of Streptomyces sp., primarily targeting bacterial infections. It exhibits notable antibacterial activity, particularly against Gram-positive bacteria. This compound is utilized in research applications to investigate its potential therapeutic effects in tumor treatment and microbial resistance studies. -
Antibiotic
A2315A, also known as Madumycin II, is an alanine-containing streptogramin A antibiotic that functions as a potent inhibitor of the peptidyl transferase center (PTC) within the ribosome. By targeting the ribosomal machinery, A2315A effectively prevents the initiation of the first cycle of peptide bond formation, demonstrating significant antibiotic activity. This compound is valuable for research focusing on ribosomal function and antibiotic mechanism of action. -
Antibiotic/Antimicrobial Peptide
Aurein 2.6 is an antimicrobial peptide that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, with minimum inhibitory concentrations (MIC) of 25 to 30 μM against various strains, including Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 2.6 is valuable for research applications involving antibiotic resistance studies and the development of new antimicrobial agents. -
Antibiotic
Okilactomycin is a lactone antibiotic derived from the culture filtrate of Streptomyces species. It exhibits antibacterial activity by inhibiting bacterial growth mechanisms, making it valuable for studying antibiotic resistance and bacterial infections. This compound can be utilized in research related to microbiology and pharmacology to further understand antibiotic properties and develop new therapeutic strategies. -
Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibiotic
Avilamycin A is an orally active antibiotic that targets bacterial pathogens, particularly effective against veterinary strains of Clostridium perfringens (MICs ≤ 0.06-0.5 mg/L) and Brachyspira hyodysenteriae (MICs = 12.5-100 μg/ml). Its potent antibacterial properties make it a valuable reagent for research focused on combating bacterial infections in veterinary medicine. Avilamycin A is often utilized in studies aiming to understand antibiotic resistance mechanisms and to develop new therapeutic strategies against resistant bacterial strains. -
Antibiotic
(R)-10,11-Dehydrocurvularin is an antibiotic derived from the secondary metabolites of Curvularia species. It exhibits concentration-dependent cytotoxicity against various human tumor cell lines, with a mean IC50 value of 1.25 µM. This compound is valuable for research applications in cancer biology and the development of novel antimicrobial agents. -
Antibiotic
Erythromycin C is an antibiotic that primarily targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent activity against a wide range of gram-positive bacteria and some gram-negative pathogens. Erythromycin C is widely used in research to study bacterial resistance mechanisms and as a model compound in antibiotic development studies. Its properties make it a valuable tool in microbiological and pharmaceutical research. -
Antibiotic
Concanamycin A is a macrolide antibiotic that functions as an inhibitor of vacuolar type H+-ATPase (V-ATPase). By inhibiting V-ATPase, Concanamycin A disrupts lysosomal acidification, making it a valuable tool in the study of T cell-mediated inflammation. Its properties allow for exploration of cellular processes related to inflammation and lysosomal function, contributing to a better understanding of various disease mechanisms. -
Antibiotic
Streptomycin is an aminoglycoside antibiotic primarily targeting bacterial protein synthesis by binding to ribosomal RNA. It exhibits potent activity against Mycobacterium tuberculosis, making it essential for tuberculosis research. In addition, Streptomycin demonstrates bactericidal properties against various bacterial infections and interferes with nucleic acid interactions. Furthermore, this compound acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, enabling its use in studies related to electrophysiological processes. -
Antibiotic Agent
Polyketomycin is a tetracyclic quinone glycoside antibiotic derived from Streptomyces sp. or Streptomyces diastatochromogenes, targeting Gram-positive bacteria with a minimal inhibitory concentration (MIC) of less than 0.2 µg/mL. This compound exhibits notable antibacterial, anticancer, and antimalarial activities, making it a valuable tool in microbiological and pharmacological research. Its diverse biological applications support investigations in antibiotic efficacy, cancer treatment, and antimalarial drug development. -
Antitumor Antibiotic
Sandramycin is a cyclic depsipeptide antibiotic with a primary mechanism of action as an antitumor agent. It exhibits potent DNA intercalation and binding, functioning effectively as a cytotoxin in antibody-drug conjugates (ADCs). Sandramycin demonstrates significant activity against Gram-positive bacteria and is recognized for its strong antitumor efficacy, making it a valuable reagent for cancer research and the development of targeted therapies. -
Nucleoside Antibiotic
Dealanylascamycin is a nucleoside antibiotic that functions as a carbonic anhydrase (CA) inhibitor, exhibiting Ki values of 167, 65.2, 234, and 143 nM for human CA isoforms I, II, IV, and IX, respectively. This compound demonstrates broad-spectrum antibacterial activity, notably effective against pathogens such as Xanthomonas citri with a minimum inhibitory concentration (MIC) of 0.4 μg/mL. Additionally, Dealanylascamycin displays significant cytotoxicity, making it a substance of interest for various biological research applications, particularly in the study of antimicrobial effects and CA inhibition. -
Antibiotic
Luisol A is an anthraquinone antibiotic analog derived from an aromatic tetraol, recognized as a major metabolite of Streptomyces, a marine actinomycete. This compound exhibits significant antibacterial activity, making it a valuable tool in the study of antibiotic mechanisms and resistance. Its application in research aids in the exploration of novel antimicrobial agents and their effects on various bacterial strains. -
Antibiotic
Agrochelin is an alkaloid antibiotic with cytotoxic properties, derived from the fermentation of marine Agrobacterium species. This compound exhibits significant cytotoxic activity against various tumor cell lines, making it a valuable tool in cancer research. Agrochelin's mechanism of action may provide insights into antibiotic efficacy and the development of novel therapeutic strategies for oncological applications. -
Antibiotic
Cefempidone is a third-generation cephalosporin antibiotic that targets penicillin-binding proteins, leading to the inhibition of bacterial cell wall synthesis. This mechanism results in effective antibacterial activity against a range of gram-positive and gram-negative bacteria. Cefempidone is primarily utilized in research applications involving the study of bacterial resistance and the development of new therapeutic strategies against bacterial infections. -
Antibiotic
Cefamandole lithium is a second-generation broad-spectrum cephalosporin antibiotic that exerts its antibacterial activity by inhibiting bacterial cell wall synthesis. This compound is effective against a variety of Gram-positive and Gram-negative bacteria. Upon metabolism, cefamandole lithium releases free N-methylthiotetrazole (NMTT), which may result in low prothrombinemia, highlighting its importance in biochemical and pharmacological research applications. -
Antibiotic
Resorcinomycin A is an antibiotic primarily targeting mycobacterial species, demonstrating potent anti-mycobacterial activity. This compound exhibits weaker activity against mycoplasma, making it a valuable reagent for research applications focused on mycobacterial infections and mechanisms of action within this class of pathogens. -
Antitumor Antibiotic
IB-96212 is an antitumor antibiotic derived from the marine bacterium Micromonospora sp. It primarily targets cancer cells, demonstrating potent activity against the P-388 leukemia cell line. Additionally, IB-96212 exhibits antimicrobial properties against Micrococcus luteus, making it a valuable compound for various research applications in cancer and microbiology studies. -
Antibiotic
A-83016F is an antibiotic compound with activity derived from an unidentified actinomycete designated A83016. This compound exhibits weak antimicrobial properties and is primarily used for research applications exploring antibiotic efficacy and microbial resistance mechanisms. Further investigation of A-83016F may provide insights into its potential therapeutic applications and bacteriologic interactions.
