Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Candidal Agent
Callophycin A is a natural metabolite derived from red seaweed, demonstrating strong antifungal activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 62.5–250 mg/L. This compound effectively diminishes fungal load in models of vaginal candidiasis and is associated with reduced inflammatory responses and modulation of immune molecules. Callophycin A is valuable for research applications focusing on antifungal therapies and the immune responses associated withCandida infections. -
Fungicide
Tetromycin C1 is a potent fungicide derived from Streptomyces species, functioning primarily as an antibiotic bactericide. This compound exhibits significant biological activity against a variety of fungal pathogens, making it valuable for research applications focused on antifungal drug development and microbial resistance studies. Its unique mechanism of action provides insight into the biological processes that underlie fungal infections and their treatment. -
Pyrone compounds
Lateropyrone is a pyranone antibiotic that primarily targets Gram-negative bacteria, exhibiting significant antimicrobial activity. It is a secondary metabolite synthesized by the oat fungal pathogen, demonstrating potential for use in pharmaceutical research to explore antibiotic resistance mechanisms and develop new antibacterial agents. Its unique structure and biological activity make it a valuable compound in studies focused on microbial interactions and pathogen inhibition. -
Biosurfactant
Surfactin is a cyclic lipopeptide biosurfactant exhibiting strong ionophoric activity by modulating the transport of mono- and divalent cations, such as calcium, across lipid bilayer membranes. This compound demonstrates significant antimicrobial properties, including antibacterial, antifungal, antimycoplasma, and hemolytic effects. Additionally, Surfactin possesses antiviral activity against various enveloped viruses, making it a valuable reagent for studies in microbiology, virology, and cell membrane research. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Secondary Metabolite
Aurofusarin is a secondary metabolite derived from the fungus Fusarium graminearum, known as a significant pathogen affecting vital crops in temperate regions. This compound exhibits antifungal properties and plays a role in the ecological interactions of plant-fungal systems. Aurofusarin is utilized in research to explore plant-pathogen interactions and the biosynthetic pathways of secondary metabolites. -
Antimicrobial Agent
11β,13-Dihydrolactucin serves as an antimicrobial agent, demonstrating significant antibacterial and antifungal properties. Additionally, this compound exhibits various biological activities, including antioxidant, anti-inflammatory, and antitumor effects. Its versatile nature makes it a valuable reagent for research applications in microbiology and cancer studies. -
Chitinase Inhibitor
Argifin is a potent chitinase inhibitor that demonstrates sub-nanomolar activity, targeting multiple chitinase enzymes. It exhibits impressive IC50 values of 0.025 μM for SmChiA from Serratia marcescens, 6.4 μM for SmChiB, 1.1 μM for Aspergillus fumigatus chitinase B1, and 4.5 μM for human chitotriosidase. Argifin is instrumental in studies exploring chitin metabolism and offers potential applications in antifungal research and elucidation of chitinase-related diseases. -
Antiplasmodial Agent
19,20-Epoxycytochalasin D is a cytochalasin derived from the fungal species Nemania sp. It exhibits significant in vitro antiplasmodial activity, making it a valuable compound for malaria research. Additionally, it demonstrates phytotoxic properties, indicating its potential use in studies related to plant biology and herbicide development. -
SDH Inhibitor
Succinate dehydrogenase-IN-2 is a potent inhibitor targeting succinate dehydrogenase (SDH) with an IC50 value of 1.22 mg/L. This compound demonstrates significant antifungal activity, effectively inhibiting a range of fungal pathogens including S. sclerotiorum, V. mali, G. graminis, R. solani, and B. cinerea, with EC50 values in the range of 0.52-3.42 mg/L. It is a valuable tool for research applications focusing on fungal infections and metabolic pathways involving SDH. -
Active Compound
Phenylpyruvic acid is a precursor to phenyllactic acid and serves as an active compound with antifungal properties. This reagent enhances the antifungal activity of various lactic acid bacterial strains when incorporated into defined growth media. Phenylpyruvic acid exhibits significant inhibitory effects against fungal contaminants such as Aspergillus niger and Penicillium roqueforti. Additionally, it influences the enzymatic activity of the pentose phosphate pathway in rat brain homogenates, notably reducing glucose-6-phosphate dehydrogenase activity. This compound is valuable for research applications in microbiology and metabolic studies. -
Telomerase
Diazaphilonic acid is a compound that targets telomerase, functioning by inhibiting its activity. Derived from the fungal strain Talaramuces flavus PF1195, it demonstrates significant potential in disrupting DNA amplification processes. This makes it a valuable reagent for research applications focused on telomere biology and cancer studies. -
Myosin I Inhibitor
ZJS178 is a selective inhibitor of myosin I, exhibiting significant antifungal activity against Fusarium graminearum. This compound effectively reduces the synthesis of the mycotoxin deoxynivalenol (DON) and is valuable for research on plant diseases, particularly wheat scab. ZJS178 serves as a potent tool for studies aimed at understanding myosin I functions in fungal pathogenesis and developing strategies for disease management in crops. -
Microbial Metabolite
Benanomicin A is a microbial metabolite derived from Actinomycetes, known for its antifungal properties. It demonstrates significant inhibitory effects on HIV-1 viral infection in MT-4 cells. This compound is useful in research applications targeting fungal infections and viral replication mechanisms. -
Antibiofilm Agent
1,3-β-Glucanase targets the β-1,3-glucan component of the biofilm matrix in Candida albicans. By degrading this polysaccharide, it effectively disrupts the biofilm structure, thereby enhancing the efficacy of antimicrobial treatments. This enzyme is utilized as an antibiofilm agent in various research applications focused on fungal infections and biofilm-related challenges. -
Antimicrobial Agent
Lapyrium chloride is a broad-spectrum antimicrobial agent that targets a variety of microorganisms. It exhibits potent antiseptic and disinfectant properties, making it suitable for use in both clinical and laboratory settings. This reagent is ideal for applications involving the control of bacterial and fungal contamination. -
Dihydroisocoumarin Derivative
Aspergillumarin B is a dihydroisocoumarin derivative isolated from the endophytic fungus Aspergillus sp. It exhibits weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis. This compound is of interest in biological research for its potential applications in studying antibacterial mechanisms and fungal metabolites. -
DHPS Inhibitor
Dihydropteroate synthase-IN-1 is a potent inhibitor of dihydropteroate synthase (DHPS), primarily targeting the folate biosynthesis pathway. This compound exhibits significant antimicrobial and antifungal properties, making it valuable for research in microbial resistance and pathogenicity studies. Additionally, Dihydropteroate synthase-IN-1 has implications in diagnostics as a potential radio imaging agent, advancing the exploration of therapeutic interventions. -
MabA (FabG1) Inhibitor
FabG1-IN-1 is a selective inhibitor of MabA (FabG1), exhibiting an IC50 of 38 µM. This compound effectively impedes the enzymatic activity of FabG1, playing a crucial role in fatty acid biosynthesis. FabG1-IN-1 is applicable in research focusing on metabolic pathways and the development of antifungal therapies targeting lipid synthesis. -
Antimicrobial Agent
Sulochrin is an antimicrobial agent derived from the metabolite produced by Aspergillus terreus var. aureus. This compound exhibits significant antimicrobial activity, making it valuable in the study of microbial interactions and the development of antifungal treatments. Sulochrin is useful for research applications involving infection models, as well as in exploring the biochemical pathways related to antimicrobial resistance. -
Asperlicin
Asperlicin D is an metabolite derived from the Aspergillus alliaceus strain (ATCC 20656), primarily involved in the regulation of fungal biosynthesis. It exhibits antifungal and antibacterial activities through inhibition of various biological pathways. Due to its potential therapeutic properties, Asperlicin D is of interest in studies related to natural product chemistry and antimicrobial drug development. -
Antifungal Agent
Antibacterial agent 230 is an antifungal agent targeting fluconazole-resistant fungi. It exhibits a minimal inhibitory concentration (MIC) ranging from 2.0 to 16.0 μg/mL, demonstrating significant efficacy against resistant strains. This compound is suitable for research applications focused on fungal resistance mechanisms and the development of new antifungal therapies. -
Polyketide
Reveromycin C is a polyketide compound originally derived from Streptomyces, exhibiting significant antifungal activity against Candida albicans, with minimum inhibitory concentrations of 2.0 μg/mL at pH 3 and above 500 μg/mL at pH 7.4. It inhibits EGF-induced mitogenic activity in Balb/MK mouse epidermal cells and effectively reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells with an EC50 of 1.58 μg/mL. Additionally, Reveromycin C suppresses the proliferation of KB cells and K562 human chronic myelogenous leukemia cells, both with an IC50 of 2.0 μg/mL, making it a valuable tool for cancer research and antifungal studies. -
Antiviral Agent
γ-Carboline is a bioactive compound primarily functioning as an antiviral agent. It exhibits significant antiviral activity against Bovine Viral Diarrhea Virus (BVDV) with an EC50 of 2.0 μM. Additionally, derivatives of γ-Carboline have demonstrated antibacterial, antifungal, and antitumor properties, making it a valuable tool for various research applications in virology and broader therapeutic studies. -
Fungicide
Bromuconazole is a triazole fungicide that targets fungal cells and demonstrates effective crop protection. In addition to its primary function, it exhibits cytotoxic properties against various cancer cell lines by inducing G0/G1 cell cycle arrest, inhibiting DNA synthesis, and triggering apoptosis through the activation of caspase-3. Bromuconazole also enhances reactive oxygen species production, influences mitochondrial function, and disrupts MAPK signaling pathways, thereby impairing the stress response in human trophoblast and endometrial cells. This reagent is suitable for research applications in glioma, colon cancer, reproductive health, and cardiac dysfunction studies. -
Antiplasmodial Agent
19,20-Epoxycytochalasin C is a cytochalasin derivative derived from the fungal species Nemania sp. This compound demonstrates significant in vitro antiplasmodial activity, making it a valuable tool for malaria research. Additionally, it exhibits phytotoxic properties, further expanding its potential applications in studying plant interactions and responses. -
Antiparasitic Agent
Sporogen AO-1 is a fungal metabolite derived from Aspergillus oryzae, functioning as an antiparasitic agent. It exhibits potent antimalarial activity, specifically targeting Plasmodium falciparum, with an IC50 value of 1.53 μM. Additionally, Sporogen AO-1 demonstrates certain levels of cytotoxicity, making it a valuable compound for research in parasitic diseases and potential therapeutic applications. -
Nematode Growth Inhibitor
5-(4-Methoxyphenyl)oxazole is a nematode growth inhibitor that targets Caenorhabditis elegans, effectively interfering with hatching and growth processes. This compound, derived from fungal culture broth, exhibits potential in studying nematode biology and assessing the efficacy of nematicidal agents. Its application in research provides valuable insights into nematode management and development. -
Antimalarial Agent
Asperaculane B is a fungal metabolite that targets Plasmodium falciparum, exhibiting a significant antimalarial activity with an IC50 of 7.89 µM. This compound effectively inhibits the development of asexual stages of P. falciparum, showing an IC50 of 3 µM, while demonstrating low cytotoxicity to human cells. Asperaculane B serves as a valuable resource for research into malaria therapies and the mechanisms of Plasmodium transmission. -
FREP1 Inhibitor
P-orlandin is a specific inhibitor of FREP1, a protein that mediates the binding of Plasmodium gametocytes and ookinetes. This fungal metabolite demonstrates potent activity in blocking Plasmodium falciparum infections in mosquito vectors, making it a valuable tool for research in malaria transmission and vector control studies. Its unique mode of action offers insights into potential strategies for disrupting the lifecycle of malaria parasites. -
Antimalarial Drug
Chevalone C is a meroterpenoid fungal metabolite that exhibits potent antimalarial activity, demonstrating an IC50 value of 25.00 μg/mL. In addition to its antimalarial properties, Chevalone C displays anti-proliferative effects against various cancer cell lines, including colon HCT116, liver HepG2, and melanoma A375. This compound is useful for research applications in the study of malaria and cancer therapeutics. -
Quorum Sensing Inhibitor
Aculene D is a quorum sensing inhibitor derived from fungal metabolites that targets the signaling mechanisms in bacteria. It effectively reduces violacein production in Chromobacterium violaceum CV026 cultures induced by N-hexanoyl-L-homoserine lactone (C6-HSL) at sub-inhibitory concentrations. This compound is valuable for research exploring bacterial communication and the modulation of biofilm formation, with potential applications in combating antibiotic resistance and developing new antimicrobial strategies. -
Streptomycin Biosynthesis Inducer
A-Factor is a potent inducer of streptomycin biosynthesis in the inactive mutant strain of Streptomyces griseus. Additionally, A-Factor promotes spore formation during the conidial development of Magnaporthe oryzae. This reagent is valuable for researchers studying antibiotic production and fungal development processes. -
Antibiofilm Agent
Antibiofilm agent-14 is a potent antibiofilm agent targeting fungal biofilm formation. It exhibits notable antifungal activity against Candida albicans strain SC5314, demonstrating a minimum inhibitory concentration (MIC) of 50 μM. This compound is valuable for research applications focusing on biofilm-related infections and strategies to combat fungal resistance. -
Antifungal Agents
Bensuldazic acid is a lipophilic 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative functioning as an antifungal agent. It exhibits significant antifungal activity, making it a valuable compound for research in fungal infections. Bensuldazic acid can also serve as a prodrug model, facilitating studies in drug development and fungal pathogenesis. -
Antimicrobial Agent
9,12,13-Trihydroxy-10-octadecenoic acid acts primarily as an antimicrobial agent. This compound exhibits significant antibacterial and antifungal properties, making it valuable for various biological research applications. It is particularly useful in studies focused on infection control and the development of novel antimicrobial therapies. -
Antifungal Agents
Bensuldazic acid sodium is a sodium salt of a 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative known for its lipophilic properties. It exhibits significant antifungal activity, functioning effectively as a prodrug model in various studies. This compound is utilized in research focused on antifungal agents and can aid in the development of novel therapeutic strategies against fungal infections. -
GlcN-6-P Synthase Inhibiotor
FMDP is a selective inhibitor of GlcN-6-P Synthase, demonstrating significant anti-candidal activity. Additionally, when covalently linked to polyethylene glycol in nanoparticle form, FMDP exhibits strong anticancer properties. This compound serves as a valuable tool in research applications focused on fungal infections and cancer therapeutics. -
AgrA Quorum-sensing Inhibitor
Apicidin D2 is a specific inhibitor of the accessory gene regulator A (AgrA), which plays a pivotal role in bacterial quorum sensing. This fungal metabolite demonstrates notable anti-virulence properties by effectively suppressing AgrA activation in Staphylococcus aureus, including methicillin-resistant strains (MRSA), without exhibiting biocidal effects. Apicidin D2 is a valuable reagent for research focused on understanding MRSA infections and developing strategies to combat quorum-sensing related pathogenicity. -
Anticancer Agent
Previridicatumtoxin is a fungal metabolite known for its antibacterial and anticancer properties. Derived from the organism P. aethiopicum, this compound demonstrates significant biological activity against cancer cells and has potential applications in cancer research and studies related to infections. Its unique mechanism of action makes it a valuable tool for exploring therapeutic strategies in oncology and microbiology. -
triazole fungicide
Ipconazole is a triazole fungicide that primarily targets the biosynthesis of ergosterol, a key component of fungal cell membranes. It exhibits potent antifungal activity, making it effective in the control of various fungal pathogens that affect rice seed and other crops. This reagent is valuable for research applications focused on plant protection strategies and the study of fungal resistance mechanisms. -
Antifungal Agent
Ayapin is a phytoalexin primarily derived from sunflower, functioning as a potent antifungal agent. It effectively inhibits the growth of Sclerotinia sclerotiorum, exhibiting an IC50 value of 0.16 mM for 50% inhibition. Ayapin is valuable for research applications focused on the mechanisms of antifungal resistance and strategies to combat sclerotinia infections. -
Anti-mycotic Agent
Tioxaprofen is an effective anti-mycotic agent that targets Trichophyton mentagrophytes and T. rubrum. Its primary mechanism of action involves acting as a potent uncoupling agent of mitochondrial respiration, disrupting the energy production in fungal cells. This compound is valuable for research focused on fungal infections and mitochondrial function, providing insights into potential therapeutic avenues. -
Antimicrobial Agent
Antimicrobial agent-30 is an effective antimicrobial agent that targets various bacterial and fungal strains. It demonstrates minimum inhibitory concentration (MIC) values ranging from 18.7 to 21.0 µg/mL against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger, and Aspergillus fumigatus. This compound is suitable for research applications involving antimicrobial susceptibility testing and the development of new antimicrobial therapies. -
Anthraquinone
Rheoemodin is an anthraquinone compound with notable antibacterial properties. Isolated from Cordyceps morakotii BCC 56811, it demonstrates significant antibacterial activity against Acinetobacter baumannii, with a minimum inhibitory concentration of 12.5 μg/mL. Additionally, Rheoemodin exhibits weak to moderate activity against mycobacterial and fungal pathogens, as well as anticancer effects in breast cancer and small cell lung cancer models. Its diverse biological activities make Rheoemodin a valuable tool for research in microbiology and cancer therapeutics. -
Aldehyde Compound
Phellandral is an aldehyde compound primarily sourced from Eucalyptus camaldulensis and Thymus seravschanicus. This compound demonstrates potent antifungal activity, particularly against the plant pathogen Aspergillus flavus. Additionally, phellandral contributes to the antibacterial properties of eucalyptus essential oil, making it valuable for research in phytopathology and natural product development. -
Anticandidal Agent
Anticandidal agent-1 is a potent broad-spectrum agent targeting Candida species, exhibiting significant anticandidal activity against Candida albicans and Candida glabrata, with MIC50 values of 8.65 and 13.51 μg/mL, respectively. This compound effectively inhibits biofilm formation by disrupting hyphal elongation and filamentation, making it a valuable tool for studying candidiasis and developing antifungal treatments. Its mechanism of action positions it as a crucial reagent for research in fungal pathogenesis and infection control. -
DGK Inhibitor
Cochlioquinone A is a potent diacylglycerol kinase (DGK) inhibitor, exhibiting ATP-competitive properties with a Ki value of 3.1 μM. Isolated from the fungal species Drechslera sacchari, Cochlioquinone A serves as a valuable tool for studying DGK's role in cellular signaling pathways. Its inhibitory effects on DGK activity make it pertinent for research in lipid signaling and related biological processes. -
Aflatoxin B1 Metabolite
Aflatoxicol is a primary metabolite of aflatoxin B1, generated by the fungal species Rhizopus. This compound exhibits mutagenic and carcinogenic properties, making it a critical subject of study in toxicology and cancer research. Aflatoxicol serves as an important reagent for analyzing the metabolic pathways and biological effects of aflatoxin exposure. Its use can aid in evaluating the risks associated with mycotoxin contamination in food and agricultural products. -
Emodin Metabolite
2-Hydroxyemodin, an active metabolite of emodin, primarily targets hepatic microsomes. This anthraquinone, derived from fungal metabolites and found in rhubarb, exhibits mutagenic activity in Salmonella typhimurium TA1537 without the need for an activation system. It is utilized in research to investigate metabolic pathways and genetic stability.
