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Pezadeftide

Catalog No.: A46598
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections.
Pezadeftide 1907724-92-8 Antifungal Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections.
Product Information
Catalog NumA46598
FormulaC234H372N70O66S8
Molecular Weight5478.41
CAS Number1907724-92-8
SequenceAla-Lys-Val-Cys-Thr-Lys-Pro-Ser-Lys-Phe-Phe-Lys-Gly-Leu-Cys-Gly-Thr-Asp-Gly-Ala-Cys-Thr-Thr-Ala-Cys-Arg-Lys-Glu-Gly-Leu-His-Ser-Gly-Tyr-Cys-Gln-Leu-Lys-Gly-Phe-Leu-Asn-Ser-Val-Cys-Val-Cys-Arg-Lys-His-Cys (Disulfide bridge:Cys4-Cys51,Cys15-Cys35,Cys21-Cys45,Cys25-Cys47)
Sequence shorteningAKVCTKPSKFFKGLCGTDGACTTACRKEGLHSGYCQLKGFLNSVCVCRKHC (Disulfide bridge:Cys4-Cys51,Cys15-Cys35,Cys21-Cys45,Cys25-Cys47)
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Peptides
Microbiology > Antifection > Fungal