Catalog No.
Product Name
Application
Product Information
Citations
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Antimicrobial Agent
Pyrithione is an antimicrobial agent that primarily inhibits membrane transport processes in fungi. It exhibits potent antibiotic activity against various fungal species, including Penicillium. When incubated with Penicillium mycelia, pyrithione significantly reduces the activity of multiple independently regulated transport systems, making it valuable for research in antifungal mechanisms and microbial resistance studies. -
Fungal
Conalbumin, also known as ovotransferrin, is a monomeric glycoprotein that primarily targets iron transport and is encoded by the avian transferrin gene. This protein, predominantly found in chicken egg white, exhibits a distinct glycosylation pattern that enhances its functionality compared to serum transferrin. Conalbumin demonstrates significant antimicrobial, antifungal, antiviral, anticancer, antioxidative, antihypertensive, and immunoregulatory activities. Its diverse biological properties make it suitable for various research applications, including studies on iron metabolism, and as an ingredient in infant formulas and food additives to promote animal health. -
Fungal Inhibitor
Sakuranetin is a cherry flavonoid phytoalexin that acts as a potent fungal inhibitor. It exhibits strong antifungal properties, along with notable anti-inflammatory and antioxidative activities. Additionally, Sakuranetin has demonstrated efficacy in ameliorating LPS-induced acute lung injury, making it a valuable compound for research in inflammation and respiratory disorders. -
Growth Regulator
Epocholeone is a growth regulator that targets various physiological processes in plants. It exhibits significant efficacy in controlling fungal infections and mitigating physiological diseases in crops, enhancing overall plant health and yield. This compound is ideal for use in agricultural research focusing on plant pathology and growth enhancement strategies. -
Antifungal Agent
T-2307 is an arylamidine with potent antifungal activity, demonstrating efficacy against a wide range of clinically important pathogens. It exhibits broad-spectrum activity with minimum inhibitory concentrations (MIC) ranging from 0.00025 to 0.0078 μg/ml against Candida species, 0.0039 to 0.0625 μg/ml against Cryptococcus neoformans, and 0.0156 to 4 μg/ml against various Aspergillus species. T-2307 is valuable for research applications focused on antifungal development and therapeutic intervention. -
Antifungal Agent
Fosmanogepix is a novel antifungal agent that selectively inhibits the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungal cells. By disrupting the localization of these critical cell wall components, Fosmanogepix compromises fungal cell wall integrity, inhibits biofilm formation, and impedes germ tube morphogenesis, ultimately curtailing fungal growth. This compound is primarily utilized in research focused on invasive fungal infections, offering valuable insights into therapeutic strategies. -
Tropone Derivatives; Tyrosinase Inhibitor; Virus Inhibitor; Funga Inhibitor
Tropolone is a seven-membered non-benzenoid aromatic compound recognized for its role as a tyrosinase inhibitor, exhibiting an IC50 value of 0.4 μM. This compound demonstrates significant anti-viral and anti-fungal properties, making it effective in a variety of therapeutic applications. Additionally, Tropolone shows enhanced effects when used in conjunction with nucleos(t)ide analogs. Its potential for research in osteosarcoma emphasizes its importance in the exploration of new treatments. -
Antifungal Antibiotic/Complex III Inhibitor
Myxothiazol is an antifungal antibiotic that acts as an inhibitor of mitochondrial electron transport chain complex III (bc1 complex). It demonstrates potent antifungal activity against various yeasts and fungi, exhibiting effective growth inhibition at concentrations ranging from 0.01 to 3 μg/ml. This compound is valuable for research applications focused on mitochondrial function and the mechanisms of antifungal resistance. -
Antifungal Cyclic Dipeptide
Cyclo(L-Phe-L-Pro) is an antifungal cyclic dipeptide that selectively targets the retinoic-acid-inducible gene-I (RIG-I) pathway, thereby inhibiting IFN-β production. Isolated from cell-free culture supernatants of Pseudomonas fluorescens and Pseudomonas alcaligenes, this compound demonstrates significant free-radical scavenging ability, with an IC50 of 24 µM in the DPPH assay. It serves as a valuable reagent in studies related to antifungal mechanisms and oxidative stress response. -
Drug Derivative
UDP-rhamnose is the activated form of rhamnose that plays a crucial role in the synthesis of rhamnose-containing glycans in fungi. This nucleotide sugar acts as a key substrate for glycosyltransferases, enabling the assembly of polysaccharides involved in the fungal cell wall. UDP-rhamnose is utilized in research focused on understanding fungal pathogenesis and the development of therapeutics for fungal infections. -
Fungicide
Pyrimethanil is an anilinopyrimidine fungicide that primarily targets the biosynthesis of methionine and other amino acids in Botrytis cinerea. This broad-spectrum contact fungicide effectively controls Botrytis spp. on a variety of crops, including fruits, vegetables, and ornamental plants. Pyrimethanil is utilized in research focused on the prevention of mold infections and the management of fungal diseases in agricultural settings. -
Lignin Intermediate
Coniferyl alcohol is a key intermediate in lignin biosynthesis with antifungal properties. It has been shown to specifically inhibit the growth of fungi such as Verticillium longisporum, as well as impede the growth of Nicotiana benthamiana seedlings. Additionally, coniferyl alcohol demonstrates potential benefits in improving cardiac dysfunction associated with renovascular hypertension and cardiac inflammation, making it valuable for research in both plant pathology and cardiovascular studies. -
Building Block
2,5-Furandimethanol serves as a versatile building block in the enzymatic synthesis of bio-based polyesters. This compound is also a significant metabolite derived from the fungus Phellinus linteus, which has been implicated in the treatment of leukemia. Additionally, 2,5-Furandimethanol may provide insights in the study of fungal infections, making it a valuable reagent in various biological research applications. -
Antifungal Agent
D-Gluconic acid potassium is a carboxylic acid that exhibits antifungal activity through its antiseptic and chelating properties. This compound is suitable for research applications in the field of mycology and can aid in the study of fungal infections and their treatment mechanisms. Its ability to chelate metal ions further enhances its potential utility in various biochemical assays. -
β-1,3-Glucan Inhibitor
Ibrexafungerp is an orally active β-1,3-glucan synthesis inhibitor with demonstrated antifungal properties. Its mechanism targets the cell wall biosynthesis pathway of fungi, making it valuable in research on Candida and Aspergillus infections. This compound is a promising candidate for studies focused on antifungal resistance and the development of new antifungal therapies. -
Antifungal
Prochloraz is an imidazole antifungal agent that primarily functions as a dual antagonist of estrogen receptors (ER) and androgen receptors (AR), as well as an aromatase inhibitor with IC50 values of 25 μM, 4 μM, and 0.3 μM, respectively. Additionally, Prochloraz activates the aryl hydrocarbon receptor (AhR) with an EC50 of 1 μM. This compound is useful in research focused on endocrine disruption and antifungal activity, making it a valuable tool for studies in toxicology and pharmacology. -
Antifungal Agent
2-Phenylethyl isothiocyanate is a potent antifungal agent targeting fungal growth and development. It significantly inhibits spore germination and mycelial growth of Alternaria alternata, exhibiting a minimum inhibitory concentration (MIC) of 1.22 mM. The antifungal action of 2-Phenylethyl isothiocyanate involves the reduction of toxin levels and disruption of cell membrane integrity, making it a valuable compound for research into fungal pathogens and potential therapeutic applications. -
Antifungal/Antibacterial/Antiviral Agent
Cyclo(L-Leu-L-Pro) is a cyclic dipeptide that serves as a broad-spectrum antibacterial, antiviral, and antifungal agent. It is particularly effective in inhibiting aflatoxin production in Aspergillus flavus and exhibits significant antibacterial activity against multi-drug resistant bacteria, especially in its cis configuration. Additionally, Cyclo(L-Leu-L-Pro) demonstrates notable antiviral properties, specifically inhibiting the influenza A virus H3N2. This compound is valuable for research applications focused on infectious diseases and microbial resistance. -
Volatile Organic Compound
2,5-Dimethylcyclohexanol is a volatile organic compound with significant antineoplastic and antiviral properties, particularly through its inhibition of SARS-CoV-2 Mpro. Additionally, it exhibits potent antifungal activity against Pseudogymnoascus destructans, compromising cell wall and membrane integrity while disturbing energy metabolism. This compound increases reactive oxygen species (ROS), ATP, superoxide anions, and glutathione (GSH) levels, while reducing catalase (CAT) and superoxide dismutase (SOD) activities. Furthermore, 2,5-Dimethylcyclohexanol influences the expression of virulence-related ribosomal genes and disrupts MAPK signaling pathways, leading to fungal cell apoptosis. -
Fungicide
(Rac)-Epoxiconazole is a chiral triazole fungicide that exhibits inhibitory activity against a wide range of fungal pathogens. This compound demonstrates long-lasting fungicidal effects, making it suitable for agricultural applications where persistent protection is essential. Its persistence in soil is noteworthy, with a reported half-life exceeding 300 days, indicating prolonged efficacy in reducing fungal populations in treated areas. -
Antifungal Agent
Sertaconazole is a broad-spectrum topical antifungal agent that primarily targets fungal cell membranes. It exhibits significant anti-inflammatory activity by activating the p38-COX-2-PGE2 signaling pathway. Additionally, Sertaconazole functions as a microtubule inhibitor, demonstrating antiproliferative effects, and inducing apoptosis and autophagy. Its ability to inhibit cellular migration makes it valuable in various research applications related to fungal infections and inflammatory conditions. -
Ras Inhibitor
(-)-Rasfonin is a natural fungal secondary metabolite that acts as an inhibitor of small G protein Ras. It exhibits significant biological activities, including the induction of apoptosis, necrosis, and autophagy in ACHN cells, a renal carcinoma cell line. This compound is instrumental for research focused on cellular death pathways and therapeutic strategies targeting Ras-mediated signaling in cancer. -
Azoxystrobin Enantiomer
(Z)-Azoxystrobin is an enantiomer of Azoxystrobin, a broad-spectrum β-methoxyacrylate fungicide. It functions by inhibiting mitochondrial respiration through binding to the Qo site of the cytochrome bc1 complex, thereby disrupting electron transfer. The compound is known to induce the production of reactive oxygen species (ROS), ultimately leading to cell apoptosis. It is primarily used in research applications involving fungal inhibition and the study of mitochondrial function. -
Nephrotoxin
Orellanine is a potent fungal nephrotoxin primarily known for its mechanism as a competitive inhibitor of alkaline phosphatase. This compound effectively induces apoptosis in proximal tubular cells and clear cell renal cell carcinoma (ccRCC) cell lines. Orellanine serves as a valuable tool for research focused on nephrotoxicity and the pathophysiology of ccRCC. -
Calcineurin Phosphatase Inhibitor
Dibefurin is a potent inhibitor of calcineurin phosphatase, a critical regulator of calcium-dependent signaling pathways. This fungal metabolite has demonstrated significant biological activity in various cellular processes, making it a valuable tool for studying immune response and neuronal signaling. Its application extends to research focused on autoimmune diseases and neurodegenerative disorders, where calcineurin activity plays a pivotal role. -
IMPase Inhibitor
L-671776 is a non-competitive inhibitor of inositol monophosphatase (IMPase), a critical enzyme in the phosphoinositide signaling pathway. This compound, derived from the fungal strain ATCC 20928B, exhibits significant potential for modulating inositol levels and can be utilized in studies investigating mood disorders, neurodegenerative diseases, and other conditions linked to inositol metabolism. Its application in biochemical research can help elucidate the role of IMPase in cellular signaling processes. -
PTP1B Inhibitor
Deoxyfunicone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), demonstrating an IC50 value of 24.3 µM through direct active site binding. This secondary fungal metabolite exhibits notable anti-inflammatory properties, making it a valuable tool for research into metabolic regulation and the treatment of inflammatory diseases. Its mechanism of action positions it as a significant compound for studies focused on diabetes and obesity-related conditions. -
Superoxide Anion Inhibitor
Tanzawaic acid B is a potent inhibitor of superoxide anion production, derived from the fungal source Penicillium citrinum. This compound has been demonstrated to mitigate oxidative stress by targeting superoxide radicals, making it valuable for research in oxidative damage and related pathologies. Its biological activity provides a useful tool for studying the effects of reactive oxygen species in various cellular models. -
Anticancer Agent
Endusamycin is an anticancer agent that inhibits protein and nucleic acid synthesis in Ehrlich ascites carcinoma cells. This selective activity contributes to its efficacy as a potential therapeutic for cancer research, while exhibiting no antibacterial or antifungal effects. Endusamycin is suitable for studies aimed at understanding cancer cell metabolism and the development of new cancer treatment strategies. -
FgGpmk1 Inhibitor
FgGpmk1-IN-1 is a selective inhibitor of the Fusarium graminearum mitogen-activated protein kinase (FgGpmk1), exhibiting an EC50 value of 3.46 μg/mL. This compound is valuable for investigating the biological role of FgGpmk1 in fungal pathogenesis and offers potential applications in the study of plant-fungal interactions. Researchers can utilize FgGpmk1-IN-1 to explore therapeutic strategies against Fusarium-related diseases. -
Heterocyclic Compound
Indazole, a heterocyclic aromatic compound, exhibits significant biological activity through its diverse derivatives. These derivatives are known for their anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal, and antitumor properties. Indazole and its derivatives are valuable tools for research into cancer, neurological disorders, cardiovascular diseases, and gastrointestinal diseases, highlighting their potential in various therapeutic applications. -
Phytoestrogen
3,7-Dihydroxyflavone is a flavonoid phytoestrogen that modulates estrogen receptors, making it a valuable compound for research in hormonal signaling pathways. It serves as an inhibitor of the human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase, demonstrating redox inhibitory activity with IC50 values of 0.6 μM and 6.0 μM, respectively. Additionally, 3,7-Dihydroxyflavone exhibits fluorescence properties, acting as a binding substrate for human serum albumin with specific excitation and emission wavelengths, rendering it useful for biochemical assays and studies related to protein binding interactions. -
Anti-Candida Agent
Antibacterial Agent 27 is a potent anti-Candida agent that targets the growth and proliferation of Candida species. This compound exhibits significant antifungal activity, making it a valuable tool for research in fungal infections and therapeutic development. Its efficacy against a range of Candida strains supports investigations into potential treatments for candidiasis and related diseases. -
Fungicide
Anilazine is a fungicide that primarily targets fungal growth by inhibiting key metabolic pathways. It effectively impedes the growth of organisms such as Rhizobium species and E. coli by disrupting glucose oxidation and succinate oxidation processes. Additionally, Anilazine demonstrates inhibitory effects on succinic dehydrogenase activity in vitro, making it a useful reagent for research applications focused on fungal metabolism and biochemical assays. -
Antimicrobial
4-Ethoxycoumarin is a coumarin derivative with demonstrated antimicrobial activity. It exerts its effects by targeting and inhibiting microbial growth, making it valuable for research into antibacterial and antifungal mechanisms. This compound is frequently utilized in studies assessing the efficacy of antimicrobial agents and investigating potential therapeutic applications in infectious diseases. -
Anti-tuberculosis Drug
MMV676584 is an investigational anti-tuberculosis drug that demonstrates inhibitory activity against Mycobacterium tuberculosis. This compound exhibits potential as a therapeutic agent for the treatment of eumycetoma, a chronic fungal infection. Its ability to combat tuberculosis positions MMV676584 as a promising candidate for further research in anti-infective therapies. -
Macrolide Compound
Sch725674 is a macrolide compound known for its antimicrobial properties, particularly against brewer's yeast and Candida albicans. The compound exhibits minimum inhibitory concentrations (MICs) of 8 μg/ml and 32 μg/ml, respectively. Its biological activity makes it suitable for research applications focused on antifungal mechanisms and the development of new antimicrobial strategies. -
Antimicrobial
17-Hydroxyventuricidin A is an antimicrobial agent known for its inhibitory effects on specific filamentous fungi, including Verticillium dahliae and Fusarium spp., as well as the Candida tropicalis strain R2 CIP203. This compound demonstrates significant antifungal activity, making it a valuable tool for research in mycology and antifungal compound development. Its mechanism of action and efficacy position it as a potential candidate for further studies in combatting fungal infections. -
Antimicrobial Agent
Cleroindicin F, also known as (-)-Rengyolone, is a potent antimicrobial agent. It exhibits significant anticandidal activity against various strains of Candida, demonstrating a minimum inhibitory concentration (MIC) as low as 12.5 µg/mL. This compound is valuable for research applications focused on antifungal therapeutics and microbial resistance studies. -
Mycotoxin
Destruxin A is a fungal cyclopeptide that targets mycotoxin pathways, exhibiting insecticidal and antiviral properties. It demonstrates significant inhibitory effects on leukemia cell lines in vitro. Additionally, Destruxin A specifically modulates the innate immune response in Drosophila melanogaster, increasing susceptibility to bacterial infections. This compound is particularly useful for research in cancer biology and immunology. -
Isothiocyanate
(6-Isothiocyanatohexyl)(methyl)sulfane is an isothiocyanate that exhibits significant antibacterial and antifungal activities. It demonstrates inhibitory effects against Bacillus subtilis and Trichophyton mentagrophytes, with a minimum inhibitory concentration of 25 μg/mL. Additionally, this compound shows anthelmintic properties against blue mussel (Mytilus edulis) and possesses antifouling capabilities when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm². Its diverse biological activities make it a valuable tool for research in microbiology and environmental science. -
Anti-Candida Albicans Agent
2,6-Dichlorodiphenylamine targets Candida albicans with demonstrated antifungal activity. This compound is a structural analogue of Diclofenac Sodium, a nonselective anti-inflammatory agent known for its inhibition of cyclooxygenase enzymes (COX-1 and COX-2). Its potent activity makes it suitable for research applications focused on antifungal mechanisms and therapeutic interventions against Candida infections. -
Fungicide
Captan is a widely utilized fungicide that targets various fungal pathogens, including Botrytis, Fusarium, Fusicoccum, and Pythium. Its primary mechanism involves the inhibition of spore germination and mycelial growth, making it effective in agricultural applications. Additionally, Captan has been observed to enhance denitrifying and total culturable bacterial populations, contributing to soil health. This compound is essential for research focused on fungal disease management and agricultural microbiology. -
Biomarker
Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine, primarily targeting fungal pathogens. It exhibits potent antifungal activity against Candida glabrata and Candida albicans, with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both species. Sphinganine-C17 also serves as an effective internal standard for the chromatographic analysis of sphingosine compounds, facilitating accurate detection and quantification in biochemical studies. -
Anti-Candidal Agent
Callophycin A is a natural metabolite derived from red seaweed, demonstrating strong antifungal activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 62.5–250 mg/L. This compound effectively diminishes fungal load in models of vaginal candidiasis and is associated with reduced inflammatory responses and modulation of immune molecules. Callophycin A is valuable for research applications focusing on antifungal therapies and the immune responses associated withCandida infections. -
Fungicide
Tetromycin C1 is a potent fungicide derived from Streptomyces species, functioning primarily as an antibiotic bactericide. This compound exhibits significant biological activity against a variety of fungal pathogens, making it valuable for research applications focused on antifungal drug development and microbial resistance studies. Its unique mechanism of action provides insight into the biological processes that underlie fungal infections and their treatment. -
Pyrone compounds
Lateropyrone is a pyranone antibiotic that primarily targets Gram-negative bacteria, exhibiting significant antimicrobial activity. It is a secondary metabolite synthesized by the oat fungal pathogen, demonstrating potential for use in pharmaceutical research to explore antibiotic resistance mechanisms and develop new antibacterial agents. Its unique structure and biological activity make it a valuable compound in studies focused on microbial interactions and pathogen inhibition. -
Biosurfactant
Surfactin is a cyclic lipopeptide biosurfactant exhibiting strong ionophoric activity by modulating the transport of mono- and divalent cations, such as calcium, across lipid bilayer membranes. This compound demonstrates significant antimicrobial properties, including antibacterial, antifungal, antimycoplasma, and hemolytic effects. Additionally, Surfactin possesses antiviral activity against various enveloped viruses, making it a valuable reagent for studies in microbiology, virology, and cell membrane research. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Secondary Metabolite
Aurofusarin is a secondary metabolite derived from the fungus Fusarium graminearum, known as a significant pathogen affecting vital crops in temperate regions. This compound exhibits antifungal properties and plays a role in the ecological interactions of plant-fungal systems. Aurofusarin is utilized in research to explore plant-pathogen interactions and the biosynthetic pathways of secondary metabolites.
