Catalog No.
Product Name
Application
Product Information
Citations
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Fungicide
Benodanil is a benzanilide fungicide that targets fungal pathogens in various agricultural applications. It exhibits effective antifungal activity, making it a valuable tool in the management of crop diseases. Researchers utilize Benodanil to study its efficacy and mechanisms of action in combating fungal infections in plants, contributing to improved agricultural practices and yield outcomes. -
Antifungal Peptides
Cyclo(L-Phe-trans-4-OH-L-Pro) is a cyclic peptide that exhibits antifungal activity by disrupting the integrity of fungal cell membranes. This compound is valuable in research focused on developing novel antifungal agents and studying the mechanisms of peptide-based antifungal strategies. Its precise mechanism of action makes it a potential candidate for addressing fungal resistance in clinical settings. -
Siderophore
Bacillibactin, a cyclic tricatecholate siderophore, primarily targets iron acquisition in bacteria by chelating iron ions (Fe3+) from the environment. This mechanism enhances bacterial survival under iron-limited conditions and exhibits direct antimicrobial activity against producing strains such as Pseudomonas aeruginosa and Aeromonas veronae, along with plant pathogens like Pseudomonas syringae. Bacillibactin is suitable for use in antibacterial and antifungal research applications, facilitating studies on microbial pathogenesis and iron metabolism. -
Fungal Inhibitor
Kakuol is a naturally derived compound that acts as a fungal inhibitor, targeting fungal cell growth and proliferation. Exhibiting potent antifungal activity, Kakuol is valuable for research applications involving the investigation of fungal infections and the development of antifungal therapies. Its mechanism of action provides insights into novel approaches for combating fungal pathogens. -
SDH Inhibitor
SDH-IN-2 is a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 value of 0.55 μg/mL, demonstrating strong antifungal activity against phytopathogenic fungi, with an average EC50 range of 3.82-9.81 μg/mL. This compound also features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its dual role as an SDH inhibitor and antifungal agent makes SDH-IN-2 a valuable tool for biochemical research and drug development studies focused on metabolic pathways and fungal diseases. -
Fungal Inhibitor
SCH 51048 is a potent fungal inhibitor that generates active metabolites with demonstrated antifungal properties. Research studies have shown that these metabolites exhibit enhanced activity, making SCH 51048 a valuable compound for investigating antifungal mechanisms and evaluating therapeutic options in fungal infections. This compound serves as a useful tool in the study of fungal biology and the development of new antifungal agents. -
Antifungal Agent
4',7-Dimethoxyisoflavone is a naturally occurring isoflavone derived from the leaves of Albizzia lebbeck, exhibiting significant antifungal properties. This compound has been shown to inhibit the growth of various fungal pathogens, making it a valuable reagent for research in antifungal drug development and related studies. Its potential applications extend to investigations focused on the mechanisms of fungal resistance and the exploration of new therapeutic strategies. -
Analogue of Pyrazine-2-carboxamide
Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide, primarily targeting microbial organisms. It exhibits significant antimicrobial activity, effectively killing and inhibiting the growth of Candida albicans, a common fungal pathogen, as well as various Gram-positive bacteria. This compound is valuable for research applications focused on antifungal and antibacterial therapies. -
olysaccharide Copolymer
L-Triguluronic acid is a linear polysaccharide copolymer consisting of three L-guluronic acid units. It serves as a precursor to alginate, a class of unbranched polyanionic polysaccharides that exhibits significant biological activities. This compound is particularly useful in research focused on the development of delivery systems for anti-fungal agents, aiding in the exploration of innovative therapeutic strategies. -
Anti-fungal Agent
Rubropunctamine is an antifungal agent derived from the red Monascus pigment. It demonstrates notable antibacterial activity alongside its efficacy against various yeast and filamentous fungi strains. Additionally, Rubropunctamine has been associated with potential embryotoxic and teratogenic effects, highlighting its relevance in toxicological research and the study of fungal infections. -
Antifungal Agent
ME1111 is an antifungal agent that targets succinate dehydrogenase in Trichophyton species. It exhibits significant efficacy against dermatophytes, making it a valuable tool for the study of fungal infections. Additionally, ME1111 demonstrates excellent penetration into human nails, facilitating research applications focused on onychomycosis and related conditions. -
Fungicide
Fenpropidin is a piperidine-based fungicide that primarily targets a variety of fungal pathogens in cereal crops. It exhibits significant antifungal activity against several human pathogenic yeasts and filamentous fungi, making it valuable in both agricultural and medical research applications. This compound is essential for studying fungal resistance mechanisms and evaluating antifungal efficacy. -
Fungal Inhibitor
Picropodophyllone is an aryltetralin lignan that functions as a fungal inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for research applications in mycology and the study of fungal pathogenesis. Its isolation from the leaves of Podophyllum hexandrum underlines its natural origin and potential therapeutic implications in combating fungal infections. -
Fungal Inhibitor
L-4-Oxalysine hydrochloride is a naturally occurring compound that acts as a fungal inhibitor. Traditionally isolated from the culture media of Streptomyces roseovirdofuscus, this reagent demonstrates significant antitumor activity. It is utilized in research studies focused on fungal pathogenesis and potential therapeutic applications in oncology. -
Bacteriostat
Sulfometuron-methyl is a potent inhibitor of the enzyme acetolactate synthase (ALS), primarily targeting this pathway to exert its herbicidal effects. In addition to its herbicidal applications, sulfometuron-methyl demonstrates significant antibacterial and antifungal properties, effectively inhibiting the activity of Salmonella typhimurium ALS II and Escherichia coli ALS III. This compound is valuable for research in fields related to microbial resistance and herbicide mechanisms. -
Fungicide Agent
Pyribencarb is a benzylcarbamate-class fungicide that functions primarily as a Qo inhibitor of cytochrome b. It demonstrates strong efficacy against various plant pathogenic fungi, particularly Botrytis cinerea and Sclerotinia sclerotiorum. This compound is valuable for research applications aimed at understanding plant-fungal interactions and developing fungal disease management strategies in agriculture. -
Antifungal Agent
Isorhapontin is an antifungal agent that targets Trichoderma cellobiohydrolase I (CBH I), exhibiting an inhibitory constant (Ki) of 57.2 μM. Additionally, Isorhapontin effectively inhibits the activity of Trichoderma endoglucanase I. This compound is valuable for research into antifungal mechanisms and enzyme activity modulation. -
Antifungal Agent
Stilbamidine dihydrochloride is a diamidine compound that functions as an antifungal agent. It exhibits efficacy against a variety of fungal infections through its inhibitory action on fungal cell growth and replication. This reagent is primarily utilized in research applications aimed at elucidating antifungal mechanisms and developing potential therapeutic strategies against fungal pathogens. -
Antifungal Agent
Macrocarpal I is a phloroglucinol-derived sesquiterpenoid that exhibits potent antifungal activity. It demonstrates significant efficacy against Candida glabrata, with an IC50 value of 0.75 μg/mL. Isolated from the juvenile leaves of Eucalyptus maideni, Macrocarpal I serves as a valuable tool for research on fungal infections and the development of antifungal therapies. -
Fungicide
Diclobutrazol is a systemic fungicide that targets fungal phytopathogens, exhibiting strong activity against rusts and powdery mildews. It is utilized in agricultural research for its effectiveness in controlling a variety of crop diseases, making it an essential tool for studying plant-pathogen interactions and developing disease management strategies in crop production. -
Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Monoterpene alcohol
Fenchyl alcohol is a monoterpene alcohol known for its antifungal properties. It effectively inhibits the formation of biofilms and hyphae in Candida albicans, making it valuable for studies on fungal infections. Additionally, Fenchyl alcohol demonstrates a significant inhibitory effect on rumen microbial activity in ruminants such as sheep and deer, aiding research in gastrointestinal microbiology. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Antifungal Agent
Sulbentine is an azole antifungal agent that exhibits both fungistatic and fungicidal activities. It serves as a locally acting antimycotic in vivo, making it valuable for treating a range of fungal infections. Sulbentine is commonly utilized in research applications focused on antifungal mechanisms and drug efficacy studies. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
SDHI
Penflufen is a potent succinate dehydrogenase inhibitor (SDHI) that targets the mitochondrial respiratory chain. This compound demonstrates broad-spectrum antifungal activity, effectively combating a variety of fungal diseases such as potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanuts. Penflufen is valuable for research applications in plant pathology and agricultural disease management. -
Antifungal Agent
Antifungal agent 18 is an antifungal agent that acts by disrupting fungal cell wall integrity through targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. It exhibits broad-spectrum antifungal activity against major human fungal pathogens, demonstrating efficacy in both in vitro and in vivo studies. This compound is suitable for research involving invasive fungal pathogens and cutaneous dermatophytes, providing valuable insight into fungal pathogenesis and potential therapeutic interventions. -
Antifungal Agent
4,6-Dimethoxysalicylaldehyde is an antifungal agent that exhibits significant activity against Candida albicans and moderate activity against Saccharomyces cerevisiae. This compound is utilized in research focusing on antifungal mechanisms and potential therapeutic applications for fungal infections. Its unique structure and activity profile make it a valuable tool for studying the efficacy of antifungal treatments. -
Antiacid/Antiulcer Agent
Magnesium silicate primarily acts as an antacid and antiulcer agent. This compound, comprised of magnesium oxide and silicon dioxide, offers effective relief from gastric discomfort and acidity. Additionally, magnesium silicate serves various research applications, including the development of food additives and the exploration of its piezoelectric properties. Its diverse capabilities also extend to use as a deodorant, decolorizing agent, and antifungal agent in biological systems. -
Anti-Candida Agent
Antibacterial Agent 27 is a potent anti-Candida agent that targets the growth and proliferation of Candida species. This compound exhibits significant antifungal activity, making it a valuable tool for research in fungal infections and therapeutic development. Its efficacy against a range of Candida strains supports investigations into potential treatments for candidiasis and related diseases. -
Fungicide
Anilazine is a fungicide that primarily targets fungal growth by inhibiting key metabolic pathways. It effectively impedes the growth of organisms such as Rhizobium species and E. coli by disrupting glucose oxidation and succinate oxidation processes. Additionally, Anilazine demonstrates inhibitory effects on succinic dehydrogenase activity in vitro, making it a useful reagent for research applications focused on fungal metabolism and biochemical assays. -
Antimicrobial
4-Ethoxycoumarin is a coumarin derivative with demonstrated antimicrobial activity. It exerts its effects by targeting and inhibiting microbial growth, making it valuable for research into antibacterial and antifungal mechanisms. This compound is frequently utilized in studies assessing the efficacy of antimicrobial agents and investigating potential therapeutic applications in infectious diseases. -
Anti-tuberculosis Drug
MMV676584 is an investigational anti-tuberculosis drug that demonstrates inhibitory activity against Mycobacterium tuberculosis. This compound exhibits potential as a therapeutic agent for the treatment of eumycetoma, a chronic fungal infection. Its ability to combat tuberculosis positions MMV676584 as a promising candidate for further research in anti-infective therapies. -
Macrolide Compound
Sch725674 is a macrolide compound known for its antimicrobial properties, particularly against brewer's yeast and Candida albicans. The compound exhibits minimum inhibitory concentrations (MICs) of 8 μg/ml and 32 μg/ml, respectively. Its biological activity makes it suitable for research applications focused on antifungal mechanisms and the development of new antimicrobial strategies. -
Antimicrobial
17-Hydroxyventuricidin A is an antimicrobial agent known for its inhibitory effects on specific filamentous fungi, including Verticillium dahliae and Fusarium spp., as well as the Candida tropicalis strain R2 CIP203. This compound demonstrates significant antifungal activity, making it a valuable tool for research in mycology and antifungal compound development. Its mechanism of action and efficacy position it as a potential candidate for further studies in combatting fungal infections. -
Antimicrobial Agent
Cleroindicin F, also known as (-)-Rengyolone, is a potent antimicrobial agent. It exhibits significant anticandidal activity against various strains of Candida, demonstrating a minimum inhibitory concentration (MIC) as low as 12.5 µg/mL. This compound is valuable for research applications focused on antifungal therapeutics and microbial resistance studies. -
Mycotoxin
Destruxin A is a fungal cyclopeptide that targets mycotoxin pathways, exhibiting insecticidal and antiviral properties. It demonstrates significant inhibitory effects on leukemia cell lines in vitro. Additionally, Destruxin A specifically modulates the innate immune response in Drosophila melanogaster, increasing susceptibility to bacterial infections. This compound is particularly useful for research in cancer biology and immunology. -
Isothiocyanate
(6-Isothiocyanatohexyl)(methyl)sulfane is an isothiocyanate that exhibits significant antibacterial and antifungal activities. It demonstrates inhibitory effects against Bacillus subtilis and Trichophyton mentagrophytes, with a minimum inhibitory concentration of 25 μg/mL. Additionally, this compound shows anthelmintic properties against blue mussel (Mytilus edulis) and possesses antifouling capabilities when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm². Its diverse biological activities make it a valuable tool for research in microbiology and environmental science. -
Anti-Candida Albicans Agent
2,6-Dichlorodiphenylamine targets Candida albicans with demonstrated antifungal activity. This compound is a structural analogue of Diclofenac Sodium, a nonselective anti-inflammatory agent known for its inhibition of cyclooxygenase enzymes (COX-1 and COX-2). Its potent activity makes it suitable for research applications focused on antifungal mechanisms and therapeutic interventions against Candida infections. -
Fungicide
Captan is a widely utilized fungicide that targets various fungal pathogens, including Botrytis, Fusarium, Fusicoccum, and Pythium. Its primary mechanism involves the inhibition of spore germination and mycelial growth, making it effective in agricultural applications. Additionally, Captan has been observed to enhance denitrifying and total culturable bacterial populations, contributing to soil health. This compound is essential for research focused on fungal disease management and agricultural microbiology. -
Biomarker
Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine, primarily targeting fungal pathogens. It exhibits potent antifungal activity against Candida glabrata and Candida albicans, with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both species. Sphinganine-C17 also serves as an effective internal standard for the chromatographic analysis of sphingosine compounds, facilitating accurate detection and quantification in biochemical studies. -
Diterpene Ester
12-Deoxyphorbol-13-isobutyrate-20-acetate is a diterpene ester that functions as a selective agonist of protein kinase C (PKC). It effectively activates PKC to facilitate the phosphorylation of troponin I and troponin T, contributing to key regulatory pathways in cardiac function. Additionally, this compound has been shown to induce dermal irritation and necrosis in murine models while demonstrating no cocarcinogenic activity. Furthermore, 12-Deoxyphorbol-13-isobutyrate-20-acetate exhibits inhibitory effects on the growth of Aspergillus carbonarius, making it valuable for research in heart failure, cardiomyopathies, and fungal infections. -
Antifugal Agent
Polyoxin D is a potent antifungal agent that acts as a chitin synthetase inhibitor. By disrupting chitin synthesis in fungal cell walls, it effectively inhibits fungal growth and proliferation. This compound is primarily utilized in research settings to study fungal pathogenesis and to explore potential therapeutic strategies against fungal infections. -
SPT Inhibitor
Myriocin is a potent serine palmitoyltransferase (SPT) inhibitor derived from various fungal species such as Myriococcum albomyces, Isaria sinclairi, and Mycelia sterilia. By inhibiting SPT, Myriocin plays a crucial role in the disruption of de novo sphingolipid synthesis. It has demonstrated significant antiviral activity, effectively suppressing the replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL. This compound is valuable for research into sphingolipid metabolism and hepatitis C virus infection mechanisms. -
FgGpmk1 Inhibitor
FgGpmk1-IN-1 is a selective inhibitor of the Fusarium graminearum mitogen-activated protein kinase (FgGpmk1), exhibiting an EC50 value of 3.46 μg/mL. This compound is valuable for investigating the biological role of FgGpmk1 in fungal pathogenesis and offers potential applications in the study of plant-fungal interactions. Researchers can utilize FgGpmk1-IN-1 to explore therapeutic strategies against Fusarium-related diseases. -
Heterocyclic Compound
Indazole, a heterocyclic aromatic compound, exhibits significant biological activity through its diverse derivatives. These derivatives are known for their anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal, and antitumor properties. Indazole and its derivatives are valuable tools for research into cancer, neurological disorders, cardiovascular diseases, and gastrointestinal diseases, highlighting their potential in various therapeutic applications. -
Phytoestrogen
3,7-Dihydroxyflavone is a flavonoid phytoestrogen that modulates estrogen receptors, making it a valuable compound for research in hormonal signaling pathways. It serves as an inhibitor of the human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase, demonstrating redox inhibitory activity with IC50 values of 0.6 μM and 6.0 μM, respectively. Additionally, 3,7-Dihydroxyflavone exhibits fluorescence properties, acting as a binding substrate for human serum albumin with specific excitation and emission wavelengths, rendering it useful for biochemical assays and studies related to protein binding interactions. -
Antifungal Agent
Fluoxastrobin is an antifungal agent that targets NAD-dependent epimerase/dehydratase, inhibiting electron transport and reducing ATP production, which effectively controls foliar diseases in tea plants. This compound induces oxidative stress by elevating reactive oxygen species (ROS) levels and lipid peroxidation, leading to DNA damage and apoptosis. Additionally, Fluoxastrobin exhibits high acute toxicity to Danio rerio embryos and larvae, making it a valuable tool in research related to tea foliar diseases, including tea red leaf spot and tea gray leaf spot. -
SAR Inducer
3-Acetonyl-3-hydroxyoxindole functions as a potent systemic acquired resistance (SAR) inducer in plants. This compound has demonstrated the ability to enhance resistance in tobacco plants against the tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole also elevates levels of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation, and phenylalanine ammonia-lyase activity, making it a valuable tool for studying plant immune responses. -
TMV Inhibitor
TMV-IN-12 is a potent inhibitor of tobacco mosaic virus (TMV), targeting the aggregation and self-assembly of TMV capsid protein (TMV-CP) with a dissociation constant (Kd) of 0.142 μM. This compound effectively disrupts TMV particle formation, thereby preventing the infection of tobacco plants. Additionally, TMV-IN-12 exhibits antifungal properties, making it a valuable reagent for studying viral and fungal interactions in plant biology and for developing strategies to combat TMV-related diseases.
