Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Monoterpene alcohol
Fenchyl alcohol is a monoterpene alcohol known for its antifungal properties. It effectively inhibits the formation of biofilms and hyphae in Candida albicans, making it valuable for studies on fungal infections. Additionally, Fenchyl alcohol demonstrates a significant inhibitory effect on rumen microbial activity in ruminants such as sheep and deer, aiding research in gastrointestinal microbiology. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Antifungal Agent
Sulbentine is an azole antifungal agent that exhibits both fungistatic and fungicidal activities. It serves as a locally acting antimycotic in vivo, making it valuable for treating a range of fungal infections. Sulbentine is commonly utilized in research applications focused on antifungal mechanisms and drug efficacy studies. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
SDHI
Penflufen is a potent succinate dehydrogenase inhibitor (SDHI) that targets the mitochondrial respiratory chain. This compound demonstrates broad-spectrum antifungal activity, effectively combating a variety of fungal diseases such as potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanuts. Penflufen is valuable for research applications in plant pathology and agricultural disease management. -
Antifungal Agent
Antifungal agent 18 is an antifungal agent that acts by disrupting fungal cell wall integrity through targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. It exhibits broad-spectrum antifungal activity against major human fungal pathogens, demonstrating efficacy in both in vitro and in vivo studies. This compound is suitable for research involving invasive fungal pathogens and cutaneous dermatophytes, providing valuable insight into fungal pathogenesis and potential therapeutic interventions. -
Antifungal Agent
4,6-Dimethoxysalicylaldehyde is an antifungal agent that exhibits significant activity against Candida albicans and moderate activity against Saccharomyces cerevisiae. This compound is utilized in research focusing on antifungal mechanisms and potential therapeutic applications for fungal infections. Its unique structure and activity profile make it a valuable tool for studying the efficacy of antifungal treatments. -
Antiacid/Antiulcer Agent
Magnesium silicate primarily acts as an antacid and antiulcer agent. This compound, comprised of magnesium oxide and silicon dioxide, offers effective relief from gastric discomfort and acidity. Additionally, magnesium silicate serves various research applications, including the development of food additives and the exploration of its piezoelectric properties. Its diverse capabilities also extend to use as a deodorant, decolorizing agent, and antifungal agent in biological systems. -
Antifungal Agent
Fosravuconazole L-lysine ethanolate, a prodrug of Ravuconazole, acts as an orally bioavailable broad-spectrum antifungal agent. It demonstrates significant efficacy against various fungal infections, making it a valuable tool for research on candidiasis, onychomycosis, and parasitemia. This compound is instrumental in exploring antifungal therapies and evaluating treatment outcomes in fungal-related diseases. -
Anticancer/Antifungal Agent
Schinifoline is a 4-quinolinone that primarily targets cancer cell proliferation and fungal infections. It exhibits potent anticancer activity by inducing G2/M phase arrest and promoting apoptosis in cancer cells, as well as enhancing their radiosensitivity. Additionally, Schinifoline demonstrates significant antifungal properties, making it relevant for research in cancer therapies and infections, particularly regarding lung cancer and Candida albicans. -
Anti-Candida Agent
Antibacterial Agent 27 is a potent anti-Candida agent that targets the growth and proliferation of Candida species. This compound exhibits significant antifungal activity, making it a valuable tool for research in fungal infections and therapeutic development. Its efficacy against a range of Candida strains supports investigations into potential treatments for candidiasis and related diseases. -
Fungicide
Anilazine is a fungicide that primarily targets fungal growth by inhibiting key metabolic pathways. It effectively impedes the growth of organisms such as Rhizobium species and E. coli by disrupting glucose oxidation and succinate oxidation processes. Additionally, Anilazine demonstrates inhibitory effects on succinic dehydrogenase activity in vitro, making it a useful reagent for research applications focused on fungal metabolism and biochemical assays. -
Antimicrobial
4-Ethoxycoumarin is a coumarin derivative with demonstrated antimicrobial activity. It exerts its effects by targeting and inhibiting microbial growth, making it valuable for research into antibacterial and antifungal mechanisms. This compound is frequently utilized in studies assessing the efficacy of antimicrobial agents and investigating potential therapeutic applications in infectious diseases. -
Anti-tuberculosis Drug
MMV676584 is an investigational anti-tuberculosis drug that demonstrates inhibitory activity against Mycobacterium tuberculosis. This compound exhibits potential as a therapeutic agent for the treatment of eumycetoma, a chronic fungal infection. Its ability to combat tuberculosis positions MMV676584 as a promising candidate for further research in anti-infective therapies. -
Diterpene Ester
12-Deoxyphorbol-13-isobutyrate-20-acetate is a diterpene ester that functions as a selective agonist of protein kinase C (PKC). It effectively activates PKC to facilitate the phosphorylation of troponin I and troponin T, contributing to key regulatory pathways in cardiac function. Additionally, this compound has been shown to induce dermal irritation and necrosis in murine models while demonstrating no cocarcinogenic activity. Furthermore, 12-Deoxyphorbol-13-isobutyrate-20-acetate exhibits inhibitory effects on the growth of Aspergillus carbonarius, making it valuable for research in heart failure, cardiomyopathies, and fungal infections. -
Antifugal Agent
Polyoxin D is a potent antifungal agent that acts as a chitin synthetase inhibitor. By disrupting chitin synthesis in fungal cell walls, it effectively inhibits fungal growth and proliferation. This compound is primarily utilized in research settings to study fungal pathogenesis and to explore potential therapeutic strategies against fungal infections. -
SPT Inhibitor
Myriocin is a potent serine palmitoyltransferase (SPT) inhibitor derived from various fungal species such as Myriococcum albomyces, Isaria sinclairi, and Mycelia sterilia. By inhibiting SPT, Myriocin plays a crucial role in the disruption of de novo sphingolipid synthesis. It has demonstrated significant antiviral activity, effectively suppressing the replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL. This compound is valuable for research into sphingolipid metabolism and hepatitis C virus infection mechanisms. -
Macrolide Compound
Sch725674 is a macrolide compound known for its antimicrobial properties, particularly against brewer's yeast and Candida albicans. The compound exhibits minimum inhibitory concentrations (MICs) of 8 μg/ml and 32 μg/ml, respectively. Its biological activity makes it suitable for research applications focused on antifungal mechanisms and the development of new antimicrobial strategies. -
Antimicrobial
17-Hydroxyventuricidin A is an antimicrobial agent known for its inhibitory effects on specific filamentous fungi, including Verticillium dahliae and Fusarium spp., as well as the Candida tropicalis strain R2 CIP203. This compound demonstrates significant antifungal activity, making it a valuable tool for research in mycology and antifungal compound development. Its mechanism of action and efficacy position it as a potential candidate for further studies in combatting fungal infections. -
Antimicrobial Agent
Cleroindicin F, also known as (-)-Rengyolone, is a potent antimicrobial agent. It exhibits significant anticandidal activity against various strains of Candida, demonstrating a minimum inhibitory concentration (MIC) as low as 12.5 µg/mL. This compound is valuable for research applications focused on antifungal therapeutics and microbial resistance studies. -
Mycotoxin
Destruxin A is a fungal cyclopeptide that targets mycotoxin pathways, exhibiting insecticidal and antiviral properties. It demonstrates significant inhibitory effects on leukemia cell lines in vitro. Additionally, Destruxin A specifically modulates the innate immune response in Drosophila melanogaster, increasing susceptibility to bacterial infections. This compound is particularly useful for research in cancer biology and immunology. -
Isothiocyanate
(6-Isothiocyanatohexyl)(methyl)sulfane is an isothiocyanate that exhibits significant antibacterial and antifungal activities. It demonstrates inhibitory effects against Bacillus subtilis and Trichophyton mentagrophytes, with a minimum inhibitory concentration of 25 μg/mL. Additionally, this compound shows anthelmintic properties against blue mussel (Mytilus edulis) and possesses antifouling capabilities when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm². Its diverse biological activities make it a valuable tool for research in microbiology and environmental science. -
Anti-Candida Albicans Agent
2,6-Dichlorodiphenylamine targets Candida albicans with demonstrated antifungal activity. This compound is a structural analogue of Diclofenac Sodium, a nonselective anti-inflammatory agent known for its inhibition of cyclooxygenase enzymes (COX-1 and COX-2). Its potent activity makes it suitable for research applications focused on antifungal mechanisms and therapeutic interventions against Candida infections. -
Fungicide
Captan is a widely utilized fungicide that targets various fungal pathogens, including Botrytis, Fusarium, Fusicoccum, and Pythium. Its primary mechanism involves the inhibition of spore germination and mycelial growth, making it effective in agricultural applications. Additionally, Captan has been observed to enhance denitrifying and total culturable bacterial populations, contributing to soil health. This compound is essential for research focused on fungal disease management and agricultural microbiology. -
Biomarker
Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine, primarily targeting fungal pathogens. It exhibits potent antifungal activity against Candida glabrata and Candida albicans, with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both species. Sphinganine-C17 also serves as an effective internal standard for the chromatographic analysis of sphingosine compounds, facilitating accurate detection and quantification in biochemical studies. -
FgGpmk1 Inhibitor
FgGpmk1-IN-1 is a selective inhibitor of the Fusarium graminearum mitogen-activated protein kinase (FgGpmk1), exhibiting an EC50 value of 3.46 μg/mL. This compound is valuable for investigating the biological role of FgGpmk1 in fungal pathogenesis and offers potential applications in the study of plant-fungal interactions. Researchers can utilize FgGpmk1-IN-1 to explore therapeutic strategies against Fusarium-related diseases. -
Heterocyclic Compound
Indazole, a heterocyclic aromatic compound, exhibits significant biological activity through its diverse derivatives. These derivatives are known for their anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal, and antitumor properties. Indazole and its derivatives are valuable tools for research into cancer, neurological disorders, cardiovascular diseases, and gastrointestinal diseases, highlighting their potential in various therapeutic applications. -
Phytoestrogen
3,7-Dihydroxyflavone is a flavonoid phytoestrogen that modulates estrogen receptors, making it a valuable compound for research in hormonal signaling pathways. It serves as an inhibitor of the human progesterone metabolizing enzyme AKR1C1 and fungal 17β-hydroxysteroid dehydrogenase, demonstrating redox inhibitory activity with IC50 values of 0.6 μM and 6.0 μM, respectively. Additionally, 3,7-Dihydroxyflavone exhibits fluorescence properties, acting as a binding substrate for human serum albumin with specific excitation and emission wavelengths, rendering it useful for biochemical assays and studies related to protein binding interactions. -
Antifungal Agent
Fluoxastrobin is an antifungal agent that targets NAD-dependent epimerase/dehydratase, inhibiting electron transport and reducing ATP production, which effectively controls foliar diseases in tea plants. This compound induces oxidative stress by elevating reactive oxygen species (ROS) levels and lipid peroxidation, leading to DNA damage and apoptosis. Additionally, Fluoxastrobin exhibits high acute toxicity to Danio rerio embryos and larvae, making it a valuable tool in research related to tea foliar diseases, including tea red leaf spot and tea gray leaf spot. -
SAR Inducer
3-Acetonyl-3-hydroxyoxindole functions as a potent systemic acquired resistance (SAR) inducer in plants. This compound has demonstrated the ability to enhance resistance in tobacco plants against the tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole also elevates levels of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation, and phenylalanine ammonia-lyase activity, making it a valuable tool for studying plant immune responses. -
TMV Inhibitor
TMV-IN-12 is a potent inhibitor of tobacco mosaic virus (TMV), targeting the aggregation and self-assembly of TMV capsid protein (TMV-CP) with a dissociation constant (Kd) of 0.142 μM. This compound effectively disrupts TMV particle formation, thereby preventing the infection of tobacco plants. Additionally, TMV-IN-12 exhibits antifungal properties, making it a valuable reagent for studying viral and fungal interactions in plant biology and for developing strategies to combat TMV-related diseases. -
Anti-Candidal Agent
Callophycin A is a natural metabolite derived from red seaweed, demonstrating strong antifungal activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 62.5–250 mg/L. This compound effectively diminishes fungal load in models of vaginal candidiasis and is associated with reduced inflammatory responses and modulation of immune molecules. Callophycin A is valuable for research applications focusing on antifungal therapies and the immune responses associated withCandida infections. -
Fungicide
Tetromycin C1 is a potent fungicide derived from Streptomyces species, functioning primarily as an antibiotic bactericide. This compound exhibits significant biological activity against a variety of fungal pathogens, making it valuable for research applications focused on antifungal drug development and microbial resistance studies. Its unique mechanism of action provides insight into the biological processes that underlie fungal infections and their treatment. -
Pyrone compounds
Lateropyrone is a pyranone antibiotic that primarily targets Gram-negative bacteria, exhibiting significant antimicrobial activity. It is a secondary metabolite synthesized by the oat fungal pathogen, demonstrating potential for use in pharmaceutical research to explore antibiotic resistance mechanisms and develop new antibacterial agents. Its unique structure and biological activity make it a valuable compound in studies focused on microbial interactions and pathogen inhibition. -
Biosurfactant
Surfactin is a cyclic lipopeptide biosurfactant exhibiting strong ionophoric activity by modulating the transport of mono- and divalent cations, such as calcium, across lipid bilayer membranes. This compound demonstrates significant antimicrobial properties, including antibacterial, antifungal, antimycoplasma, and hemolytic effects. Additionally, Surfactin possesses antiviral activity against various enveloped viruses, making it a valuable reagent for studies in microbiology, virology, and cell membrane research. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Secondary Metabolite
Aurofusarin is a secondary metabolite derived from the fungus Fusarium graminearum, known as a significant pathogen affecting vital crops in temperate regions. This compound exhibits antifungal properties and plays a role in the ecological interactions of plant-fungal systems. Aurofusarin is utilized in research to explore plant-pathogen interactions and the biosynthetic pathways of secondary metabolites. -
Antimicrobial Agent
11β,13-Dihydrolactucin serves as an antimicrobial agent, demonstrating significant antibacterial and antifungal properties. Additionally, this compound exhibits various biological activities, including antioxidant, anti-inflammatory, and antitumor effects. Its versatile nature makes it a valuable reagent for research applications in microbiology and cancer studies. -
Chitinase Inhibitor
Argifin is a potent chitinase inhibitor that demonstrates sub-nanomolar activity, targeting multiple chitinase enzymes. It exhibits impressive IC50 values of 0.025 μM for SmChiA from Serratia marcescens, 6.4 μM for SmChiB, 1.1 μM for Aspergillus fumigatus chitinase B1, and 4.5 μM for human chitotriosidase. Argifin is instrumental in studies exploring chitin metabolism and offers potential applications in antifungal research and elucidation of chitinase-related diseases. -
Antiplasmodial Agent
19,20-Epoxycytochalasin D is a cytochalasin derived from the fungal species Nemania sp. It exhibits significant in vitro antiplasmodial activity, making it a valuable compound for malaria research. Additionally, it demonstrates phytotoxic properties, indicating its potential use in studies related to plant biology and herbicide development. -
SDH Inhibitor
Succinate dehydrogenase-IN-2 is a potent inhibitor targeting succinate dehydrogenase (SDH) with an IC50 value of 1.22 mg/L. This compound demonstrates significant antifungal activity, effectively inhibiting a range of fungal pathogens including S. sclerotiorum, V. mali, G. graminis, R. solani, and B. cinerea, with EC50 values in the range of 0.52-3.42 mg/L. It is a valuable tool for research applications focusing on fungal infections and metabolic pathways involving SDH. -
Active Compound
Phenylpyruvic acid is a precursor to phenyllactic acid and serves as an active compound with antifungal properties. This reagent enhances the antifungal activity of various lactic acid bacterial strains when incorporated into defined growth media. Phenylpyruvic acid exhibits significant inhibitory effects against fungal contaminants such as Aspergillus niger and Penicillium roqueforti. Additionally, it influences the enzymatic activity of the pentose phosphate pathway in rat brain homogenates, notably reducing glucose-6-phosphate dehydrogenase activity. This compound is valuable for research applications in microbiology and metabolic studies. -
Telomerase
Diazaphilonic acid is a compound that targets telomerase, functioning by inhibiting its activity. Derived from the fungal strain Talaramuces flavus PF1195, it demonstrates significant potential in disrupting DNA amplification processes. This makes it a valuable reagent for research applications focused on telomere biology and cancer studies. -
Myosin I Inhibitor
ZJS178 is a selective inhibitor of myosin I, exhibiting significant antifungal activity against Fusarium graminearum. This compound effectively reduces the synthesis of the mycotoxin deoxynivalenol (DON) and is valuable for research on plant diseases, particularly wheat scab. ZJS178 serves as a potent tool for studies aimed at understanding myosin I functions in fungal pathogenesis and developing strategies for disease management in crops. -
Fungicide
Bromuconazole is a triazole fungicide that targets fungal cells and demonstrates effective crop protection. In addition to its primary function, it exhibits cytotoxic properties against various cancer cell lines by inducing G0/G1 cell cycle arrest, inhibiting DNA synthesis, and triggering apoptosis through the activation of caspase-3. Bromuconazole also enhances reactive oxygen species production, influences mitochondrial function, and disrupts MAPK signaling pathways, thereby impairing the stress response in human trophoblast and endometrial cells. This reagent is suitable for research applications in glioma, colon cancer, reproductive health, and cardiac dysfunction studies. -
Antiplasmodial Agent
19,20-Epoxycytochalasin C is a cytochalasin derivative derived from the fungal species Nemania sp. This compound demonstrates significant in vitro antiplasmodial activity, making it a valuable tool for malaria research. Additionally, it exhibits phytotoxic properties, further expanding its potential applications in studying plant interactions and responses. -
Antiparasitic Agent
Sporogen AO-1 is a fungal metabolite derived from Aspergillus oryzae, functioning as an antiparasitic agent. It exhibits potent antimalarial activity, specifically targeting Plasmodium falciparum, with an IC50 value of 1.53 μM. Additionally, Sporogen AO-1 demonstrates certain levels of cytotoxicity, making it a valuable compound for research in parasitic diseases and potential therapeutic applications. -
Nematode Growth Inhibitor
5-(4-Methoxyphenyl)oxazole is a nematode growth inhibitor that targets Caenorhabditis elegans, effectively interfering with hatching and growth processes. This compound, derived from fungal culture broth, exhibits potential in studying nematode biology and assessing the efficacy of nematicidal agents. Its application in research provides valuable insights into nematode management and development. -
Antimalarial Agent
Asperaculane B is a fungal metabolite that targets Plasmodium falciparum, exhibiting a significant antimalarial activity with an IC50 of 7.89 µM. This compound effectively inhibits the development of asexual stages of P. falciparum, showing an IC50 of 3 µM, while demonstrating low cytotoxicity to human cells. Asperaculane B serves as a valuable resource for research into malaria therapies and the mechanisms of Plasmodium transmission.
