MK 886

Catalog No.: A13346

leukotriene biosynthesis inhibitor

MK 886 Chemical Structure

CAS NO. 118414-82-7

MK-886 is an inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes).

Availability: In stock

Package Price Qty
10 mg
$110.00
25 mg
$240.00
50 mg
$410.00
100 mg
$630.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MK-886 is an inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes).
Targets
5-lipoxygenase-activating protein (FLAP) PPARα COX-1 COX-2
N/A8 μM58 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.18 mL 105.91 mL 211.83 mL
0.5 mM 4.24 mL 21.18 mL 42.37 mL
1 mM 2.12 mL 10.59 mL 21.18 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 472.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13346
Actions Inhibitor
M. Wt 472.08
Formula C27H34ClNO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 118414-82-7
Synonyms L-663,536, MK-886, MK886, L663536, L-663536
SMILES CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl

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