N-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections.
N-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections.
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