Catalog No.
Product Name
Application
Product Information
Citations
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Natural Product
Mauritianin is a natural product classed as a kaempferol glycoside, primarily recognized for its role as a topoisomerase I inhibitor. Isolated from the flowers and leaves of Acalypha indica, Mauritianin exhibits significant biological activities, including hepatoprotective, neuroprotective, and renoprotective effects. Additionally, it has been shown to enhance vascular tone when used in combination with Alcesefoliside, making it valuable for various pharmacological research applications. -
Alkaloid
Luotonin F is an alkaloid extracted from the aerial parts of P. nigellastrum Bunge, known for its inhibitory action on human topoisomerase II. This compound exhibits significant cytotoxic activity against mouse leukemia P-388 cells, making it a valuable tool in cancer research. Its potent biological effects suggest potential applications in the development of novel therapeutic strategies targeting neoplastic diseases. -
Cytochalasan Alkaloid
19-O-Acetylchaetoglobosin A is a cytochalasan alkaloid derived from the fungal metabolite C. globosum, known for its ability to inhibit actin polymerization. This compound exhibits significant cytotoxic activity against HeLa cervical cancer cells, making it a valuable tool for cancer research and the study of cell motility and structure. Its distinct biological properties contribute to investigations in cancer biology and the development of potential therapeutic approaches. -
Water-Soluble Phenolic Acid
Salviamarinic acid A is a water-soluble phenolic acid derived from Salvia miltiorrhiza, known for its potent anti-pulmonary fibrosis activity. This compound enhances cell viability, promotes cell motility, and increases E-cadherin expression while reducing levels of TGF-β1, α-SMA, and Collagen I. Salviamarinic acid A is a valuable tool for research focused on pulmonary fibrosis and related therapeutic investigations. -
Alkaloid
Aposcopolamine is an alkaloid isolated from Datura ferox, known for its ability to bind closely with acetylcholinesterase (ACHE), adrenergic receptor alpha-2A (ADRA2A), and muscarinic receptor subtype 2 (CHRM2). This compound is of significant interest in Alzheimer's disease research due to its potential effects on cholinergic signaling pathways. Aposcopolamine serves as a valuable tool in investigating neurodegenerative mechanisms and developing therapeutic strategies. -
Alkaloid
13-Hydroxylupanine is an alkaloid derived from sweet lupins, known for its ability to modulate ganglionic transmission. This compound significantly reduces cardiac contractility and induces contraction of uterine smooth muscle. It is utilized in research to explore cardiovascular function and smooth muscle pharmacodynamics. -
Diterpenoid Compound
Rhodojaponin VI is a diterpenoid compound that primarily targets the N-Ethylmaleimide-sensitive fusion protein (NSF). It exhibits significant biological activity by blocking the MDM2-Notch1 signaling pathway, thereby reducing the expression of MDM2 and Notch1, and inhibits NSF-mediated Cav2.2 trafficking, leading to decreased Cav2.2 current intensity. Rhodojaponin VI demonstrates therapeutic potential in alleviating glomerulonephritis progression and protecting against podocyte injury in passive Heymann nephritis models. Additionally, it possesses antinociceptive properties, making it a valuable reagent for research in nephritis and pain mechanisms. -
Natural Product
Pipercide is a natural amide derived from the fruits of Piper nigrum. This compound exhibits notable larvicidal activity against mosquitoes, operating through modulation of the nervous system by inducing repetitive discharges in the central nerve cord. Pipercide serves as a potential insecticide, making it a valuable tool for research on pest management and vector control. -
Alkaloid
Atanine is an alkaloid known for its antiparasitic activity, primarily targeting various parasitic organisms. Isolated from the medicinal plant Evodia rutaecarpa, Atanine demonstrates potential in the study of parasitic infections, offering insights for therapeutic development and biological research in this area. Its unique mechanism and efficacy make it a valuable reagent for exploring drug discovery and natural product research. -
Pesticide
Juncin E is a diterpenoid extracted from the soft coral Junceella juncea, known for its potent insecticidal properties. This compound has demonstrated significant efficacy against the larvae of key agricultural pests, specifically the southern corn rootworm and the tobacco armyworm. Juncin E serves as a valuable tool for researchers investigating natural pesticide alternatives in agricultural practices. -
Dammarane Triterpenoid
Cabraleahydroxylactone is a dammarane triterpenoid that exhibits potent antimycobacterial activity against Mycobacterium tuberculosis. This compound is valuable in research focusing on the development of novel anti-tubercular therapies. Its ability to disrupt mycobacterial growth makes it a significant candidate for further investigation in the fight against tuberculosis. -
Natural Product
Cassiachromone is a natural product derived from Cassia siamea. It exhibits various biological activities, including antioxidant and anti-inflammatory properties. This compound is primarily utilized in research applications exploring natural compounds' therapeutic potential and biochemical mechanisms of action. -
Alkaloid
Dehatrine is a dibenzylisoquinoline alkaloid that exhibits significant antiplasmodial activity. Isolated from the Indonesian medicinal plant Beilschmiedia madang, Dehatrine is of particular interest in malaria research. Its potential to inhibit malaria parasites makes it a valuable tool for studies aimed at understanding and developing treatments for this disease. -
Aminomethylphenol
JPC-3210 is an orally active aminomethylphenol that targets the hemoglobin digestion pathway in malaria parasites. Exhibiting significant anti-malarial activity, it has a mean IC50 ranging from 2.5 to 19 nM and demonstrates inhibitory effects on CYP2D6 and CYP3A4 isozymes. In vivo studies show that JPC-3210 effectively suppresses P. berghei infection in mice and offers prophylactic protection. This compound is suitable for research on malaria prevention strategies and the exploration of mechanisms in anti-malarial drug development. -
Natural Product
7-Methoxy-β-carboline-1-propionic acid is a natural product with demonstrated cytotoxic and antimalarial properties. This compound is extracted from the roots of Eurycoma longifolia, making it of interest in research focused on anti-cancer and anti-parasitic applications. Its biological activity highlights its potential utility in the development of therapeutic agents against malignancies and malaria. -
Alkaloid
Atherosperminine is a naturally occurring alkaloid that exhibits significant antiplasmodial activity with an IC50 of 5.80 μM. This compound acts as a potent reductant and possesses metal-chelating properties, making it valuable for various biochemical applications. Additionally, Atherosperminine demonstrates antioxidant capacity by scavenging the free radical DPPH, with an IC50 of 29.56 μg/mL. Its non-specific relaxant effect on the trachealis highlights its potential for respiratory research. -
Natural Product
27-Hydroxymangiferonic acid is a triterpenoid naturally derived from the leaves of Mangifera indica. This compound exhibits significant biological activities, including anti-inflammatory and antioxidant properties. It is commonly utilized in research exploring natural product pharmacology and potential therapeutic applications related to oxidative stress and inflammation-related conditions. -
Phenol
2-Methylcardol triene is a phenolic compound that exhibits potent α-glucosidase inhibition with an IC50 of 39.6 μM. Notably, this compound demonstrates schistosomicidal activity, effectively eliminating 100% of adult Schistosoma mansoni worms within 24 hours at concentrations of 100 and 200 μM. Additionally, 2-Methylcardol triene serves as a valuable precursor for synthesizing mono- and bis-benzoxazines, making it a versatile reagent for various chemical and biological research applications. -
Glucoside
Peruvianoside II is a flavanone glucoside that serves as a research tool in studies of glucoside compounds. While it does not exhibit inhibitory activity against HIV-1 reverse transcriptase and integrase at concentrations below 100 μM, its extraction from the leaves of Thevetia peruviana makes it of interest in phytochemical and biological research applications. Researchers may explore its potential effects within broader biological contexts or evaluate the properties of related compounds. -
Natural Products
Rengynic acid is a natural product isolated from the seeds of Forsythia suspensa, known for its potent antiviral activity against respiratory syncytial virus (RSV). Its unique chemical structure and mechanism of action make it a valuable compound for research into antiviral therapies and the study of viral infections. Further investigation of Rengynic acid may provide insights into potential applications for treating respiratory diseases. -
Antiviral Agent
Kuguacin N is a natural compound extracted from the vines and leaves of Momordica charantia, functioning primarily as an antiviral agent. This compound demonstrates significant antiviral activity, making it a valuable tool for research in virology and therapeutic applications against viral infections. Its unique mechanism of action offers insights into the development of novel antiviral strategies. -
Natural Product
Kadsulignan N is a natural product that exhibits anti-HIV activity, with an effective concentration (EC50) of 43.56 μM. Additionally, Kadsulignan N serves as a ligand for COX-2, showing a binding affinity (Ki) of 72.24 nM. This compound is valuable for research applications focused on viral inhibition and inflammatory processes. -
Natural Compound
Tremuloidin is a natural compound and a derivative of salicylic acid sourced from Homalium cochinchinensis. It exhibits modest antiviral activity against HIV-1, making it a useful reagent for research into antiviral mechanisms and potential therapeutic applications. Its unique chemical structure may offer insights into the development of new antiviral strategies. -
Natural Product
Ganosinensic acid C is a triterpenoid compound derived from Ganoderma lucidum, demonstrating significant biological activity as an anti-tumor agent. It exhibits potent anti-prostate cancer and anti-inflammatory properties, alongside the capacity to inhibit HIV-1 protease. Ganosinensic acid C has an IC50 of 10.5 μM against the highly metastatic human lung cancer cell line 95D and an IC50 of 13.2 μM against the cervical cancer cell line HeLa, highlighting its potential for cancer research applications. -
Sesquiterpenoid
5-Hydroxynoracronycine is a sesquiterpenoid that selectively inhibits Leishmania, HIV-1 protease, and nitric oxide production. Demonstrating an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for DPPH free radical scavenging, this compound exhibits significant anti-leishmanial, anti-HIV, antioxidant, and antibacterial activities. 5-Hydroxynoracronycine is valuable for research focused on leishmaniasis, HIV infection, and diseases related to excessive inflammation. -
Flavonoid Compound
Morin 3-O-β-D-glucopyranoside is a natural flavonoid compound known for its multifaceted biological activities, including antifungal, anticancer, and antioxidant properties. This compound effectively inhibits key enzymes such as reverse transcriptase, protein-tyrosine kinase, and xanthine oxidase, contributing to its anti-HIV and anti-arteriosclerotic effects. Additionally, Morin 3-O-β-D-glucopyranoside exhibits superoxide scavenging capabilities, making it a valuable tool for research in cancer, virology, and oxidative stress. -
Triterpenoid
Melliferone is a triterpenoid derived from Brazilian propolis, known for its potential anti-inflammatory and antioxidant properties. It has been shown to exhibit biological activities that may influence immune response and cellular signaling pathways. Melifirone is utilized in research exploring therapeutic applications in inflammation and oxidative stress-related conditions. -
Pyrrole Alkaloid
Baculiferin A is a DOPA-derived pyrrole alkaloid primarily isolated from the Chinese marine sponge Iotrochota baculifera. This compound exhibits notable anti-HIV activity, making it a valuable tool for research in virology and potential therapeutic applications. Its unique chemical structure and biological properties provide opportunities for the investigation of novel antiviral strategies. -
Antiviral agent
Suksdorfin is an antiviral agent extracted from the fruits of Lomatium suksdorfii. This compound demonstrates activity against HIV-1, indicating its potential use in the study of antiviral therapies and HIV-related research. Its unique mechanism may offer insights into novel treatments for viral infections. -
Nature Product
Lancifodilactone F is a natural product isolated from the leaves and stems of Schisandra lancifolia. This compound exhibits significant anti-HIV activity with an EC50 of 20.69 μg/mL, demonstrating potential as a therapeutic agent. Additionally, Lancifodilactone F shows cytotoxic effects on C8166 cells, with a CC50 greater than 200 μg/mL, making it relevant for cancer research applications. -
Natural Compound
Swietemahalactone is a natural compound derived from Swietenia mahagoni, primarily known for its antibacterial properties. This compound demonstrates significant activity against Escherichia coli, making it a valuable tool for microbiological research. Swietemahalactone may be utilized in studies investigating natural antimicrobial agents and their potential therapeutic applications. -
Alkaloid
(-)-Codonopsine is an alkaloid known for its antibacterial properties, specifically targeting Gram-positive bacteria, including *Staphylococcus aureus*. This compound is valuable for research applications focused on bacterial infections and the development of new antibacterial agents. Its unique mechanism makes it a relevant tool in the study of antimicrobial resistance and therapeutic interventions. -
Carbazole Alkaloid
3,4-Dimethoxy-1,2-dimethyl-9H-carbazole is a carbazole alkaloid that serves as an important precursor in the synthesis of baccamycin. This compound demonstrates noteworthy biological activity, contributing to research focused on the development of antimicrobial agents and the exploration of alkaloid biosynthesis pathways. Its unique structural properties make it valuable in chemical research and medicinal chemistry applications. -
Triterpenoids
3,29-O-Dibenzoyloxykarounidiol is a triterpene benzoate derivative with a primary mechanism targeting triterpenoids. It is isolated from the fruit of Momordica grosvenori and exhibits potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). This compound is valuable for research applications related to viral inhibition and oncogenesis. -
Triterpenoid
Karounidiol is a triterpenoid derived from the plant Trichosanthes kirilowii. It exhibits notable biological activities, including anti-inflammatory and antioxidant properties, making it a useful compound for various research applications. Karounidiol is of interest in studies exploring its potential therapeutic effects in inflammatory diseases and oxidative stress-related conditions. -
Triterpenoid Compound
Ganolactone is a triterpenoid compound known for its weak inhibitory effect on Epstein-Barr virus (EBV) early antigen expression. This biological activity makes Ganolactone a valuable tool for research focused on viral infections and the mechanisms of immune response. Its potential applications extend to studies investigating the role of triterpenoids in antiviral therapies and cellular signaling pathways. -
Alkaloid
(-)-Mecambridine is a retroprotoberberine alkaloid isolated from Papaver pseudocanescens M. Pop. This compound exhibits weak inhibitory activity against poliovirus type 1, suggesting potential applications in virology research. Its unique structure and activity make it a valuable tool for studying antiviral mechanisms and developing therapeutic strategies against viral infections. -
Alkaloid
Cephaeline hydrochloride is a phenolic alkaloid derived from Indian Ipecac roots. This compound demonstrates significant antiviral activity, particularly inhibiting Zika virus (ZIKV) and Ebola virus (EBOV) infections. Its biological properties make it a valuable tool for research focused on viral pathogenesis and the development of antiviral therapies. -
Bioactive Iridoid Glycoside
Picroside IV is a bioactive iridoid glycoside primarily derived from the roots of Picrorhiza scrophulariiflora. This compound exhibits a range of biological activities, including neuroprotection, anti-inflammatory, hypoglycemic, and anticancer properties. Picroside IV is utilized in research focusing on its therapeutic potential for various diseases, including neurodegenerative disorders and liver-related conditions. Additionally, it shows promise in the study of oxidative stress and inflammation. -
Flavonoid Derivative
Cis-ccc_R08 is a flavonoid derivative that acts as an inhibitor of covalently closed circular DNA (cccDNA) associated with hepatitis B virus (HBV) infection. This compound demonstrates significant potential for research focused on antiviral mechanisms and the exploration of therapeutic targets for HBV. Its role in disrupting cccDNA synthesis makes it valuable for investigating HBV replication and persistence. -
Alkaloid
Sophoranol is an alkaloid derived from Sophora flavescens, exhibiting significant antiviral properties. This compound demonstrates potent activity against hepatitis B virus (HBV) and shows strong antiviral effects against respiratory syncytial virus (RSV), with an IC50 value of 10.4 μg/mL. Sophoranol is useful for research into viral pathogenesis and potential therapeutic approaches targeting HBV and RSV infections. -
Natural Product
Kadsulignan L is a lignan compound derived from the stems of Kadsura japonica. It exhibits various biological activities, including potential anti-inflammatory and antioxidant properties. This natural product is valuable in pharmacological research and the study of plant-derived therapeutics for various health applications. -
Triterpenoid Saponin
Platycodin D3 is a triterpenoid saponin derived from Platycodon grandiflorum, known for its diverse pharmacological properties. It demonstrates significant anti-inflammatory effects, regulates airway mucus secretion, and enhances respiratory function in asthma models. Additionally, Platycodin D3 exhibits antiviral activity by inhibiting hepatitis C virus (HCV) replication, with an IC50 value of 8 μg/mL against HCV NS5B RNA-dependent RNA polymerase. This compound is suitable for research in asthma, HCV infection, and inflammatory diseases. -
Natural Extract
Cinnamomum zeylanicum extract is a natural extract sourced from the bark and leaves of the Cinnamomum zeylanicum tree. This extract is abundant in bioactive compounds, including cinnamaldehyde, eugenol, and linalool, which confer significant anti-inflammatory, antibacterial, and antioxidant activities. Commonly utilized in various research applications, this extract is valuable for studies focusing on inflammation, microbial resistance, and oxidative stress. -
Natural Compound
DJK-5 is a natural compound derived from Mimulus clevelandii that exhibits significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide production. This activity positions DJK-5 as a valuable tool for researching inflammation and immune responses. Its application can be pivotal in studies focused on the modulation of nitric oxide pathways in various biological systems. -
Natural Product
D-Hexamannuronic acid is a natural product derived from marine brown algae and select Gram-negative bacteria. This alginate oligomer exhibits potential biological activity relevant to studies on pain and vascular dementia. It serves as a valuable reagent for researchers investigating the pathophysiology of these conditions and exploring therapeutic applications. -
Natural Extract
Soapnut extract is a natural nonionic surfactant known for its skin conditioning properties. It demonstrates significant antibacterial and detergency capabilities while remaining non-polluting and skin-softening. Additionally, Soapnut extract exhibits anti-inflammatory, antioxidant, free radical scavenging, and anticoagulant activities, making it suitable for various biological research applications including skin care formulations and studies on oxidative stress. -
Natural Extract
Curcuma longa extract is a natural extract derived from the rhizome of the turmeric plant, primarily containing curcumin as its active component. This extract exhibits significant anti-inflammatory and antioxidant properties, making it valuable in the study of various conditions, including arthritis, joint pain, and muscle soreness. Additionally, it serves as a potential therapeutic agent in research focused on chronic inflammatory diseases and other related pathologies. -
Antimalarial Flavonoid
Anisofolin A is a flavonoid derived from Anisomeles indica, exhibiting significant antimalarial activity with an IC50 of 4.39 μM. Additionally, it demonstrates antimycobacterial properties, showing an IC50 of 4.50 μM against Mycobacterium tuberculosis H37Ra. This compound is valuable for research applications focused on malaria and tuberculosis, offering potential insights into therapeutic development. -
Terpenoid Compound
Cephalonic acid is a pentaprenyl terpenoid compound, primarily targeting bacterial membranes. This compound exhibits weak antibacterial activity against Staphylococcus aureus, making it of interest in studies regarding microbial resistance and potential therapeutic applications. Additionally, its unique structure can be explored in the synthesis of novel bioactive molecules.
