Catalog No.
Product Name
Application
Product Information
Citations
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Substrate For ALDH, Precursor Compound for Phenolic Compounds
3-Hydroxybenzaldehyde serves as a substrate for aldehyde dehydrogenase (ALDH) and acts as a precursor for diverse phenolic compounds, including Protocatechuic aldehyde. This compound exhibits vasculoprotective properties, demonstrating potential in both in vitro and in vivo studies. Research applications primarily focus on its role in atherosclerosis, making it a valuable reagent for biochemical investigations related to cardiovascular health. -
Disaccharide Linker
Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering. -
Natural Product
2,4-Dihydroxy-3-methoxyacetophenone is a natural product with potential antioxidant properties. This compound is commonly utilized in biological research to investigate its effects on cellular processes and to evaluate its role in various biochemical pathways. Its unique structure and functional groups may provide insights into mechanisms of action relevant to pharmacology and medicinal chemistry. -
Triterpenoid
Cyclocarin A is a triterpenoid compound isolated from the leaves of Cyclocarya paliurus. This compound exhibits weak inhibitory activity against several enzymes, including α-glucosidase, lipase, DPP-IV, and aldose reductase, along with limited effects on human cancer cell lines (IC50 > 10 μM). Despite its modest biological activity, Cyclocarin A may serve as a useful tool for research in enzyme inhibition and cancer biology. -
Lignan Glucoside
(+)-Medioresinol Di-O-β-D-glucopyranoside is a lignan glucoside that acts as a potent inhibitor of 3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterase. This compound is of significant interest in biomedical research due to its potential to modulate cyclic AMP signaling pathways, which are crucial for various physiological processes. It is applicable in studies related to cellular signaling, pharmacology, and the development of therapeutic agents targeting cyclic AMP-related disorders. -
Alkaloid
β-Carboline-1-carboxylic acid is a β-carboline alkaloid that acts as an inhibitor of phosphodiesterase and indoleamine 2,3-dioxygenase, demonstrating an IC50 of 96 µM for cAMP phosphodiesterase. It exhibits significant biological activities including anti-inflammatory, antifibrotic, antitumor, and antibacterial properties, with cytotoxic effects on tumor cells. Furthermore, this compound inhibits inflammation via the NF-κB/p65 pathway and reverses epithelial-mesenchymal transition (EMT). It also shows potent antibacterial effects against Staphylococcus aureus and Escherichia coli, with IC50 values of 47.70 μg/mL and 19.17 μg/mL, respectively. -
Flavonoid Compound
Camellianin B is a flavonoid compound that serves as a metabolite of Camellianin A. This compound exhibits antioxidant properties and inhibits the activity of angiotensin-converting enzyme (ACE). Camellianin B is valuable in research related to oxidative stress and cardiovascular health, providing insights into the modulation of enzyme activity and potential therapeutic applications. -
Anthraquinone Dye
Disperse Blue 60 is an anthraquinone dye recognized for its application in textile coloration. Its primary mechanism involves interaction with fibers, imparting vibrant blue hues to a variety of fabrics. This compound is utilized in research related to dye chemistry, textile engineering, and environmental monitoring, contributing to studies on dye degradation and its effects on ecosystems. -
Fluorescent Unnatural Amino Acid
L-ANAP TFA is a fluorescent unnatural amino acid (Uaa) that is genetically encodable and exhibits polarity-sensitive fluorescence characteristics. It is utilized in protein labeling and imaging applications, allowing for the study of protein dynamics and interactions in live cells. This reagent facilitates advanced research in protein engineering and biosensing, providing insights into cellular processes at the molecular level. -
Natural Product
Clausine Z (1,6-Dihydroxy-9H-carbazole-3-carboxaldehyde) is a natural product that functions as a selective inhibitor of cyclin-dependent kinase 5 (CDK5). This compound demonstrates significant neuroprotective activity and has potential applications in the study of neurodegenerative disorders. Its unique mechanism of action makes it a valuable tool for research in cell cycle regulation and neuronal function. -
Natural Product
Nigakinone is a natural alkaloid that exhibits significant pharmacological activity. It is primarily derived from the Kumu plant and is known for its potential therapeutic effects. This compound is of interest in research applications focusing on drug discovery and the study of natural product biosynthesis. -
Flavonoid
Kurarinone is a flavonoid compound known for its ability to inhibit the differentiation of Th1 and Th17 cells, thereby impacting the pathogenesis of experimental autoimmune encephalomyelitis. This compound exhibits notable antitumor and anti-inflammatory properties, making it a valuable tool in research focused on autoimmune diseases and cancer. Applications include investigating immunomodulatory effects and elucidating mechanisms underlying inflammatory responses. -
Biflavonoid
Neocryptomerin is a biflavonoid that demonstrates notable inhibitory activity against cancer cell lines such as U251, MCF-7, and HeLa. Additionally, Neocryptomerin displays strong binding affinities within the active pocket of SARS-CoV-2, highlighting its potential as a lead compound in the search for therapeutic agents against COVID-19. This compound is of interest for research in cancer biology and antiviral drug development. -
Natural Compound
Jaceidin triacetate is a natural compound that target SARS-CoV-2 main protease (Mpro). It demonstrates significant antiviral activity with an IC50 of 11.9 μM, effectively inhibiting the replication of SARS-CoV-2 in Vero E6 cells. This compound serves as a valuable tool for research in the development of therapeutic agents against COVID-19 and related viral infections. -
Natural product
Kuguacin R is a cucurbitane-type triterpenoid derived from Momordica charantia L. This compound exhibits significant anti-inflammatory, antimicrobial, and antiviral properties, making it a valuable tool in biological research. Kuguacin R is utilized in studies aimed at understanding its mechanisms of action in various diseases and its potential therapeutic applications. -
Alkaloid Antibiotic
Hatomamicin is an alkaloid antibiotic with potent activity against Gram-positive bacteria. Isolated from the culture filtrate of Sucrose Polyspora, it serves as a valuable tool in antibacterial research. Its mechanism of action and biological activity make it relevant for studies focused on developing new antimicrobial therapies. -
Shikonin Pigment
Isovalerylshikonin (IVS) is a derivative of the shikonin pigment, primarily extracted from the root epidermis of Echium italicum L. It exhibits notable antioxidant and anti-inflammatory properties, contributing to its potential applications in research on cellular protection and modulation of inflammatory responses. IVS is of interest in studies investigating the mechanisms underlying various biological activities, including its effects on wound healing and cancer cell proliferation. -
Antiviral Agent
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate) acts primarily as an antiviral agent. Extracted from the traditional herbal medicine Andrographis paniculata, it exhibits significant immunostimulatory, anti-infective, and anti-inflammatory properties. This compound is commonly utilized in research focused on therapeutic strategies for viral pneumonia and upper respiratory tract infections. -
Phenolic Compound
Strictinin is a phenolic compound derived from Pu'er teas, primarily known for its potential antiviral and antibacterial properties. This compound exhibits laxative activity by accelerating intestinal transit, without influencing gastric emptying or increasing food intake in rat models. Strictinin is useful in pharmacological research, particularly in studies focusing on gut motility and microbial interactions. -
Natural product
Phloroglucide is a natural product primarily derived from ferns, known for its diverse biological activities. It exhibits antioxidant properties, which may contribute to the protection of cells from oxidative stress. This compound is utilized in various research applications, including studies on plant biochemistry and investigating natural antioxidants in health-related research. -
Natural Compound
Lucidadiol is a natural compound derived from Ganoderma lucidum, functioning as an acetylcholinesterase inhibitor with an IC50 value of 31 μM. This compound also demonstrates antiviral activity against influenza virus type A and herpes simplex virus type 1 (HSV-1). Lucidadiol is valuable for research applications exploring neuroprotective mechanisms and viral infection inhibition. -
Natural Product
2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol is a derivative of 9,10-dihydrophenanthrene, with primary applications in natural product research. Isolated from Juncus compressus, this compound demonstrates significant anticancer activity against cervical and ovarian cancers. Additionally, it serves as a valuable tool in the study of HSV-2 virus, contributing to ongoing research in infectious diseases and cancer therapeutics. -
Natural Product
Pinellic acid is a natural product derived from the medicinal plant Pinelliae tuber. It serves as an effective oral adjuvant for enhancing the efficacy of nasal influenza vaccines. Its unique properties make it valuable for research in immunology and vaccine development, providing insights into adjuvant mechanisms and potential therapeutic applications. -
Natural Product
Methyl 4-O-feruloylquinate is a natural product derived from Stemona japonica, primarily characterized by its anti-H5N1 activity. This compound exhibits a protective effect in MDCK cells, demonstrating a 3% protective rate at a concentration of 5 μM. It is utilized in research to explore antiviral mechanisms and the therapeutic potential of natural compounds against influenza viruses. -
Natural Product
Nuezhenidic acid is a natural product derived from the fruits of Ligustrum lucidum. It exhibits inhibitory activity against influenza A virus, making it a promising candidate for antiviral research. This compound can be used in studies focused on the development of novel antiviral agents and the exploration of natural products with therapeutic potential against viral infections. -
Fungal Piperazine Alkaloid
Herquline A is a fungal piperazine alkaloid known for its inhibitory effects on platelet aggregation and the replication of the influenza virus. This compound demonstrates antiviral and antithrombotic properties, making it a valuable tool for research into viral infections and cardiovascular diseases. Its unique biological activity offers potential applications in investigations focused on antifungal and antiviral drug development. -
Iridoid Glucoside
Shanziside is an iridoid glucoside derived from Phlomis tuberosa L. It exhibits notable anti-inflammatory and antioxidant activities, making it a valuable compound for research into inflammatory pathways and oxidative stress. This compound is of interest in studies aimed at understanding its potential therapeutic applications in various disease models. -
Natural Product
Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobioside is a flavonoid compound that primarily targets chemosensory proteins in the pest Cylas formicarius. It binds to CforCSP5 (Ki: 1.429 μM) and CforOBP3 (Ki: 3.697 μM), implicating its role in the recognition of host plant volatiles. Additionally, it serves as an inhibitor of Sb28GST (IC50: 0.13 mM), making it a valuable reagent for research into anti-schistosome agents and insect sensory biology. -
Glucose Disaccharide
Isomaltose is a glucose disaccharide that promotes the secretion of granulocyte-colony stimulating factor (G-CSF) through heat-induced oxidative polymerization of glucose units into high-molecular-weight compounds. It exhibits a low glycemic index and slow hydrolysis, providing prebiotic properties beneficial for gut microbiota modulation. Notably, isomaltose has been shown to reduce in vivo colonization of Cryptosporidium parvum in neonatal mice, making it applicable in researching Cryptosporidium parvum infections and related gastrointestinal disorders. -
Insecticidal Ingredient
Pyrethrin II is an insecticidal ingredient derived from the natural compounds known as pyrethrins, which are extracted from Chrysanthemum cinerariifolium. This compound exhibits potent insecticidal activity by targeting the nervous system of insects, leading to paralysis and eventual death. Pyrethrin II is widely utilized in agricultural and household pest control applications, contributing to effective management of insect populations while minimizing environmental impact. -
Bioactive Alkaloid
Mahanine is a bioactive carbazole alkaloid known for its diverse biological properties. It demonstrates potent anticancer activity across various cancer cell types, making it valuable for cancer research. Additionally, Mahanine exhibits significant antileishmanial effects, positioning it as a useful compound for studying Leishmania infections and related therapeutic approaches. -
Bioactive Diterpenoid
Columbin is a bioactive diterpenoid furanolactone derived from Calumbae radix, known for its anti-inflammatory and anti-trypanosomal activities. It exhibits selective inhibition of COX-2 with an EC50 of 53.1 μM while showing significantly lower activity on COX-1 (EC50 of 327 μM). This compound is utilized in various research applications aimed at understanding inflammatory pathways and developing strategies against trypanosomiasis. -
Alkaloid
Allosecurinine is an alkaloid derived from the plant Phyllanthus glaucus, classified within the Securinega group of compounds. This natural product exhibits notable biological activity, potentially influencing various cellular pathways. Its research applications include the study of neuroprotective effects and exploration of its role in modulating signaling pathways in cellular models. -
Alkaloid
β-Carboline-1-propionic acid is an alkaloid derived from Ailanthus altissima, known for its potential antileishmanial properties. This compound exhibits biological activity that may inhibit the growth of Leishmania parasites, making it a valuable reagent for studies focused on leishmaniasis treatment and related therapeutic applications in parasitology. -
Natural Compound
5-Hydroxy-3,7-dimethoxyflavone, a natural compound derived from Kaempferia parviflora, exhibits a range of biological activities. This flavonoid is noted for its potential role in research exploring the modulation of cellular pathways. While it demonstrates minimal toxicity to malaria parasites, fungi, and bacteria, its utility in studying various biological systems offers valuable insights for drug discovery and development. -
Triterpenoid Antimalarial Agent
1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid is a triterpenoid that acts as an antimalarial agent, targeting Plasmodium species responsible for malaria. Isolated from Agrimonia pilosa, this compound exhibits notable antidiabetic activity, thereby highlighting its potential applications in both malaria and metabolic disorder research. Its diverse biological properties make it a valuable reagent for studying triterpenoid functions in medicinal chemistry and pharmacology. -
Alkaloid
(±)-Stylopine hydrochloride is an alkaloid compound derived from Corydalis tubers, known for its anti-inflammatory and anti-parasitic properties. This compound serves as a valuable tool in biological research, particularly in studies focused on inflammation and parasitic infections. Researchers may utilize (±)-Stylopine hydrochloride to investigate its mechanisms of action and potential therapeutic applications. -
Natural Product
Digitolutein is a natural product derived from the stem bark and roots of Morinda lucida Benth. It demonstrates significant inhibitory activity against Plasmodium falciparum, with an IC50 value of 12.92 μg/mL. This compound serves as a valuable tool for studies focused on antimalarial efficacy and exploration of novel therapeutic agents for infection-related research. -
Antiplasmodial Agent
Cheilanthifoline is an alkaloid extracted from Corydalis calliantha, primarily functioning as an antiplasmodial agent. It demonstrates significant antiplasmodial activity against Plasmodium falciparum, with IC50 values of 0.90 μg/mL for the wild type (TM4) strain and 1.22 μg/mL for the multidrug resistant (K1) strain. This compound is valuable for research focused on malaria treatment and exploring novel therapeutic options. -
Phenolic Compound
4-Methyl-3-nitrophenol is a phenolic compound recognized for its role as a soft electrophile. It demonstrates significant toxicity towards ciliate organisms, exhibiting a log IC50 value of -3.740 against Tetrahymena pyriformis. This compound is valuable in studies of environmental toxicology and the mechanisms of cellular toxicity. -
Anti-Babesial Agent
Bruceine J is a quassinoid extracted from the fruits of Brucea javanica, exhibiting potent anti-Babesial activity. This compound is valuable for research focused on treating babesiosis, a disease caused by protozoan parasites in the genus Babesia. Its unique mechanism of action may provide insights into developing new therapeutic agents against this significant veterinary and human health concern. -
Anthraquinone Glycoside
Xanthopurpurin, an anthraquinone glycoside, exhibits significant biological activity through its antiviral properties against rotavirus and HIV. Isolated from the rhizome of Rubia akane, this compound also demonstrates a potent inhibitory effect on collagen-induced platelet aggregation. Additionally, Xanthopurpurin has been identified as a potential agent in preventing peanut allergy, making it a valuable reagent for research in virology and immunology. -
Non-Starch Polysaccharide
α-D-Galactose is a non-starch polysaccharide that plays a critical role in various biological processes. It exhibits antioxidant properties, demonstrates anti-tumor activities, and has immunomodulatory effects, making it valuable for cancer and immune research. Additionally, α-D-Galactose has been shown to possess anti-HIV functions, offering potential applications in virology and therapeutic development. -
Natural Product
4-Deoxy-4α-phorbol is a tetracyclic diterpene derived from E. desmondi that serves as a significant natural product. It plays a crucial role in the semisynthesis of inhibitors targeting the HIV-1-induced cytopathic effects in MT-4 cells, as well as in the development of 4α-phorbol esters. This compound is valuable for research applications in virology and therapeutic development. -
Phenolic Marker
(-)-Rabdosiin is a phenolic marker derived from Symphytum officinale L. This compound exhibits notable antioxidant properties and demonstrates neuroprotective effects, making it a valuable tool for studies related to oxidative stress and neurodegenerative conditions. Additionally, (-)-Rabdosiin has shown potential anti-HIV activity, providing insights for therapeutic research in virology. -
Natural Product
5-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound derived from Myrica esculenta, primarily known for its weak inhibitory activity against angiotensin-converting enzyme (ACE). This compound may aid in research related to cardiovascular health and the modulation of blood pressure. Its unique structure and biological properties make it a valuable tool for studies involving natural products and their pharmacological implications. -
Nature Product
Epifriedelanol acetate is a natural product derived from Pachysandra terminalis Sieb. This compound exhibits various biological activities, making it useful for research in pharmacology and natural product chemistry. Its unique structure and properties may provide insights into the development of new therapeutic agents and contribute to the study of secondary metabolites in medicinal plants. -
Phenols
Cannabigerorcin is a phenolic compound derived from cannabis, characterized by a diphenol backbone and a terpene side chain. It plays a significant role in cannabinoid biosynthesis and metabolic processes. This compound can undergo reaction with radiolabeled methylmagnesium carbonate (MMC) to achieve 14C-labeling of its carboxyl group, making radiolabeled Cannabigerorcin a valuable tool in biochemical research focused on understanding the mechanisms of cannabinoid production in plants. -
Natural Product
Mudanpioside C is a monoterpenoid derived from Paeonia lactiflora Pall. It exhibits significant biological activity, including anti-inflammatory and antioxidant properties, making it a valuable compound for research in natural products and phytotherapy. Its potential applications in studies of cancer, cardiovascular diseases, and neuroprotection further highlight its relevance in the investigation of therapeutic agents. -
Naphthoquinone Derivative
Eleutherin is a naphthoquinone derivative recognized for its protective effects against injury in human umbilical vein endothelial cells (HUVECs). Derived from the edible bulbs of Eleutherine americana, it exhibits significant biological activity that can be leveraged in research applications focused on vascular health and endothelial cell function.
