5-Hydroxynoracronycine is a sesquiterpenoid that selectively inhibits Leishmania, HIV-1 protease, and nitric oxide production. Demonstrating an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for DPPH free radical scavenging, this compound exhibits significant anti-leishmanial, anti-HIV, antioxidant, and antibacterial activities. 5-Hydroxynoracronycine is valuable for research focused on leishmaniasis, HIV infection, and diseases related to excessive inflammation.
5-Hydroxynoracronycine is a sesquiterpenoid that selectively inhibits Leishmania, HIV-1 protease, and nitric oxide production. Demonstrating an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for DPPH free radical scavenging, this compound exhibits significant anti-leishmanial, anti-HIV, antioxidant, and antibacterial activities. 5-Hydroxynoracronycine is valuable for research focused on leishmaniasis, HIV infection, and diseases related to excessive inflammation.
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