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Alkaloid
Atanine is an alkaloid known for its antiparasitic activity, primarily targeting various parasitic organisms. Isolated from the medicinal plant Evodia rutaecarpa, Atanine demonstrates potential in the study of parasitic infections, offering insights for therapeutic development and biological research in this area. Its unique mechanism and efficacy make it a valuable reagent for exploring drug discovery and natural product research. -
Pesticide
Juncin E is a diterpenoid extracted from the soft coral Junceella juncea, known for its potent insecticidal properties. This compound has demonstrated significant efficacy against the larvae of key agricultural pests, specifically the southern corn rootworm and the tobacco armyworm. Juncin E serves as a valuable tool for researchers investigating natural pesticide alternatives in agricultural practices. -
Dammarane Triterpenoid
Cabraleahydroxylactone is a dammarane triterpenoid that exhibits potent antimycobacterial activity against Mycobacterium tuberculosis. This compound is valuable in research focusing on the development of novel anti-tubercular therapies. Its ability to disrupt mycobacterial growth makes it a significant candidate for further investigation in the fight against tuberculosis. -
Natural Product
Cassiachromone is a natural product derived from Cassia siamea. It exhibits various biological activities, including antioxidant and anti-inflammatory properties. This compound is primarily utilized in research applications exploring natural compounds' therapeutic potential and biochemical mechanisms of action. -
Alkaloid
Dehatrine is a dibenzylisoquinoline alkaloid that exhibits significant antiplasmodial activity. Isolated from the Indonesian medicinal plant Beilschmiedia madang, Dehatrine is of particular interest in malaria research. Its potential to inhibit malaria parasites makes it a valuable tool for studies aimed at understanding and developing treatments for this disease. -
Aminomethylphenol
JPC-3210 is an orally active aminomethylphenol that targets the hemoglobin digestion pathway in malaria parasites. Exhibiting significant anti-malarial activity, it has a mean IC50 ranging from 2.5 to 19 nM and demonstrates inhibitory effects on CYP2D6 and CYP3A4 isozymes. In vivo studies show that JPC-3210 effectively suppresses P. berghei infection in mice and offers prophylactic protection. This compound is suitable for research on malaria prevention strategies and the exploration of mechanisms in anti-malarial drug development. -
Natural Product
7-Methoxy-β-carboline-1-propionic acid is a natural product with demonstrated cytotoxic and antimalarial properties. This compound is extracted from the roots of Eurycoma longifolia, making it of interest in research focused on anti-cancer and anti-parasitic applications. Its biological activity highlights its potential utility in the development of therapeutic agents against malignancies and malaria. -
Alkaloid
Atherosperminine is a naturally occurring alkaloid that exhibits significant antiplasmodial activity with an IC50 of 5.80 μM. This compound acts as a potent reductant and possesses metal-chelating properties, making it valuable for various biochemical applications. Additionally, Atherosperminine demonstrates antioxidant capacity by scavenging the free radical DPPH, with an IC50 of 29.56 μg/mL. Its non-specific relaxant effect on the trachealis highlights its potential for respiratory research. -
Natural Product
27-Hydroxymangiferonic acid is a triterpenoid naturally derived from the leaves of Mangifera indica. This compound exhibits significant biological activities, including anti-inflammatory and antioxidant properties. It is commonly utilized in research exploring natural product pharmacology and potential therapeutic applications related to oxidative stress and inflammation-related conditions. -
Phenol
2-Methylcardol triene is a phenolic compound that exhibits potent α-glucosidase inhibition with an IC50 of 39.6 μM. Notably, this compound demonstrates schistosomicidal activity, effectively eliminating 100% of adult Schistosoma mansoni worms within 24 hours at concentrations of 100 and 200 μM. Additionally, 2-Methylcardol triene serves as a valuable precursor for synthesizing mono- and bis-benzoxazines, making it a versatile reagent for various chemical and biological research applications. -
Glucoside
Peruvianoside II is a flavanone glucoside that serves as a research tool in studies of glucoside compounds. While it does not exhibit inhibitory activity against HIV-1 reverse transcriptase and integrase at concentrations below 100 μM, its extraction from the leaves of Thevetia peruviana makes it of interest in phytochemical and biological research applications. Researchers may explore its potential effects within broader biological contexts or evaluate the properties of related compounds. -
Natural Products
Rengynic acid is a natural product isolated from the seeds of Forsythia suspensa, known for its potent antiviral activity against respiratory syncytial virus (RSV). Its unique chemical structure and mechanism of action make it a valuable compound for research into antiviral therapies and the study of viral infections. Further investigation of Rengynic acid may provide insights into potential applications for treating respiratory diseases. -
Natural Compound
Lucidadiol is a natural compound derived from Ganoderma lucidum, functioning as an acetylcholinesterase inhibitor with an IC50 value of 31 μM. This compound also demonstrates antiviral activity against influenza virus type A and herpes simplex virus type 1 (HSV-1). Lucidadiol is valuable for research applications exploring neuroprotective mechanisms and viral infection inhibition. -
Natural Product
2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol is a derivative of 9,10-dihydrophenanthrene, with primary applications in natural product research. Isolated from Juncus compressus, this compound demonstrates significant anticancer activity against cervical and ovarian cancers. Additionally, it serves as a valuable tool in the study of HSV-2 virus, contributing to ongoing research in infectious diseases and cancer therapeutics. -
Natural Product
Pinellic acid is a natural product derived from the medicinal plant Pinelliae tuber. It serves as an effective oral adjuvant for enhancing the efficacy of nasal influenza vaccines. Its unique properties make it valuable for research in immunology and vaccine development, providing insights into adjuvant mechanisms and potential therapeutic applications. -
Natural Product
Methyl 4-O-feruloylquinate is a natural product derived from Stemona japonica, primarily characterized by its anti-H5N1 activity. This compound exhibits a protective effect in MDCK cells, demonstrating a 3% protective rate at a concentration of 5 μM. It is utilized in research to explore antiviral mechanisms and the therapeutic potential of natural compounds against influenza viruses. -
Natural Product
Nuezhenidic acid is a natural product derived from the fruits of Ligustrum lucidum. It exhibits inhibitory activity against influenza A virus, making it a promising candidate for antiviral research. This compound can be used in studies focused on the development of novel antiviral agents and the exploration of natural products with therapeutic potential against viral infections. -
Fungal Piperazine Alkaloid
Herquline A is a fungal piperazine alkaloid known for its inhibitory effects on platelet aggregation and the replication of the influenza virus. This compound demonstrates antiviral and antithrombotic properties, making it a valuable tool for research into viral infections and cardiovascular diseases. Its unique biological activity offers potential applications in investigations focused on antifungal and antiviral drug development. -
Iridoid Glucoside
Shanziside is an iridoid glucoside derived from Phlomis tuberosa L. It exhibits notable anti-inflammatory and antioxidant activities, making it a valuable compound for research into inflammatory pathways and oxidative stress. This compound is of interest in studies aimed at understanding its potential therapeutic applications in various disease models. -
Natural Product
Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobioside is a flavonoid compound that primarily targets chemosensory proteins in the pest Cylas formicarius. It binds to CforCSP5 (Ki: 1.429 μM) and CforOBP3 (Ki: 3.697 μM), implicating its role in the recognition of host plant volatiles. Additionally, it serves as an inhibitor of Sb28GST (IC50: 0.13 mM), making it a valuable reagent for research into anti-schistosome agents and insect sensory biology. -
Glucose Disaccharide
Isomaltose is a glucose disaccharide that promotes the secretion of granulocyte-colony stimulating factor (G-CSF) through heat-induced oxidative polymerization of glucose units into high-molecular-weight compounds. It exhibits a low glycemic index and slow hydrolysis, providing prebiotic properties beneficial for gut microbiota modulation. Notably, isomaltose has been shown to reduce in vivo colonization of Cryptosporidium parvum in neonatal mice, making it applicable in researching Cryptosporidium parvum infections and related gastrointestinal disorders. -
Insecticidal Ingredient
Pyrethrin II is an insecticidal ingredient derived from the natural compounds known as pyrethrins, which are extracted from Chrysanthemum cinerariifolium. This compound exhibits potent insecticidal activity by targeting the nervous system of insects, leading to paralysis and eventual death. Pyrethrin II is widely utilized in agricultural and household pest control applications, contributing to effective management of insect populations while minimizing environmental impact. -
Bioactive Alkaloid
Mahanine is a bioactive carbazole alkaloid known for its diverse biological properties. It demonstrates potent anticancer activity across various cancer cell types, making it valuable for cancer research. Additionally, Mahanine exhibits significant antileishmanial effects, positioning it as a useful compound for studying Leishmania infections and related therapeutic approaches. -
Bioactive Diterpenoid
Columbin is a bioactive diterpenoid furanolactone derived from Calumbae radix, known for its anti-inflammatory and anti-trypanosomal activities. It exhibits selective inhibition of COX-2 with an EC50 of 53.1 μM while showing significantly lower activity on COX-1 (EC50 of 327 μM). This compound is utilized in various research applications aimed at understanding inflammatory pathways and developing strategies against trypanosomiasis. -
Alkaloid
Allosecurinine is an alkaloid derived from the plant Phyllanthus glaucus, classified within the Securinega group of compounds. This natural product exhibits notable biological activity, potentially influencing various cellular pathways. Its research applications include the study of neuroprotective effects and exploration of its role in modulating signaling pathways in cellular models. -
Alkaloid
β-Carboline-1-propionic acid is an alkaloid derived from Ailanthus altissima, known for its potential antileishmanial properties. This compound exhibits biological activity that may inhibit the growth of Leishmania parasites, making it a valuable reagent for studies focused on leishmaniasis treatment and related therapeutic applications in parasitology. -
Natural Compound
5-Hydroxy-3,7-dimethoxyflavone, a natural compound derived from Kaempferia parviflora, exhibits a range of biological activities. This flavonoid is noted for its potential role in research exploring the modulation of cellular pathways. While it demonstrates minimal toxicity to malaria parasites, fungi, and bacteria, its utility in studying various biological systems offers valuable insights for drug discovery and development. -
Triterpenoid Antimalarial Agent
1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid is a triterpenoid that acts as an antimalarial agent, targeting Plasmodium species responsible for malaria. Isolated from Agrimonia pilosa, this compound exhibits notable antidiabetic activity, thereby highlighting its potential applications in both malaria and metabolic disorder research. Its diverse biological properties make it a valuable reagent for studying triterpenoid functions in medicinal chemistry and pharmacology. -
Alkaloid
(±)-Stylopine hydrochloride is an alkaloid compound derived from Corydalis tubers, known for its anti-inflammatory and anti-parasitic properties. This compound serves as a valuable tool in biological research, particularly in studies focused on inflammation and parasitic infections. Researchers may utilize (±)-Stylopine hydrochloride to investigate its mechanisms of action and potential therapeutic applications. -
Natural Product
Digitolutein is a natural product derived from the stem bark and roots of Morinda lucida Benth. It demonstrates significant inhibitory activity against Plasmodium falciparum, with an IC50 value of 12.92 μg/mL. This compound serves as a valuable tool for studies focused on antimalarial efficacy and exploration of novel therapeutic agents for infection-related research. -
Antiplasmodial Agent
Cheilanthifoline is an alkaloid extracted from Corydalis calliantha, primarily functioning as an antiplasmodial agent. It demonstrates significant antiplasmodial activity against Plasmodium falciparum, with IC50 values of 0.90 μg/mL for the wild type (TM4) strain and 1.22 μg/mL for the multidrug resistant (K1) strain. This compound is valuable for research focused on malaria treatment and exploring novel therapeutic options. -
Phenolic Compound
4-Methyl-3-nitrophenol is a phenolic compound recognized for its role as a soft electrophile. It demonstrates significant toxicity towards ciliate organisms, exhibiting a log IC50 value of -3.740 against Tetrahymena pyriformis. This compound is valuable in studies of environmental toxicology and the mechanisms of cellular toxicity. -
Anti-Babesial Agent
Bruceine J is a quassinoid extracted from the fruits of Brucea javanica, exhibiting potent anti-Babesial activity. This compound is valuable for research focused on treating babesiosis, a disease caused by protozoan parasites in the genus Babesia. Its unique mechanism of action may provide insights into developing new therapeutic agents against this significant veterinary and human health concern. -
Anthraquinone Glycoside
Xanthopurpurin, an anthraquinone glycoside, exhibits significant biological activity through its antiviral properties against rotavirus and HIV. Isolated from the rhizome of Rubia akane, this compound also demonstrates a potent inhibitory effect on collagen-induced platelet aggregation. Additionally, Xanthopurpurin has been identified as a potential agent in preventing peanut allergy, making it a valuable reagent for research in virology and immunology. -
Non-Starch Polysaccharide
α-D-Galactose is a non-starch polysaccharide that plays a critical role in various biological processes. It exhibits antioxidant properties, demonstrates anti-tumor activities, and has immunomodulatory effects, making it valuable for cancer and immune research. Additionally, α-D-Galactose has been shown to possess anti-HIV functions, offering potential applications in virology and therapeutic development. -
Natural Product
4-Deoxy-4α-phorbol is a tetracyclic diterpene derived from E. desmondi that serves as a significant natural product. It plays a crucial role in the semisynthesis of inhibitors targeting the HIV-1-induced cytopathic effects in MT-4 cells, as well as in the development of 4α-phorbol esters. This compound is valuable for research applications in virology and therapeutic development. -
Phenolic Marker
(-)-Rabdosiin is a phenolic marker derived from Symphytum officinale L. This compound exhibits notable antioxidant properties and demonstrates neuroprotective effects, making it a valuable tool for studies related to oxidative stress and neurodegenerative conditions. Additionally, (-)-Rabdosiin has shown potential anti-HIV activity, providing insights for therapeutic research in virology. -
Antiviral Agent
Kuguacin N is a natural compound extracted from the vines and leaves of Momordica charantia, functioning primarily as an antiviral agent. This compound demonstrates significant antiviral activity, making it a valuable tool for research in virology and therapeutic applications against viral infections. Its unique mechanism of action offers insights into the development of novel antiviral strategies. -
Natural Product
Kadsulignan N is a natural product that exhibits anti-HIV activity, with an effective concentration (EC50) of 43.56 μM. Additionally, Kadsulignan N serves as a ligand for COX-2, showing a binding affinity (Ki) of 72.24 nM. This compound is valuable for research applications focused on viral inhibition and inflammatory processes. -
Natural Compound
Tremuloidin is a natural compound and a derivative of salicylic acid sourced from Homalium cochinchinensis. It exhibits modest antiviral activity against HIV-1, making it a useful reagent for research into antiviral mechanisms and potential therapeutic applications. Its unique chemical structure may offer insights into the development of new antiviral strategies. -
Natural Product
Ganosinensic acid C is a triterpenoid compound derived from Ganoderma lucidum, demonstrating significant biological activity as an anti-tumor agent. It exhibits potent anti-prostate cancer and anti-inflammatory properties, alongside the capacity to inhibit HIV-1 protease. Ganosinensic acid C has an IC50 of 10.5 μM against the highly metastatic human lung cancer cell line 95D and an IC50 of 13.2 μM against the cervical cancer cell line HeLa, highlighting its potential for cancer research applications. -
Sesquiterpenoid
5-Hydroxynoracronycine is a sesquiterpenoid that selectively inhibits Leishmania, HIV-1 protease, and nitric oxide production. Demonstrating an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for DPPH free radical scavenging, this compound exhibits significant anti-leishmanial, anti-HIV, antioxidant, and antibacterial activities. 5-Hydroxynoracronycine is valuable for research focused on leishmaniasis, HIV infection, and diseases related to excessive inflammation. -
Flavonoid Compound
Morin 3-O-β-D-glucopyranoside is a natural flavonoid compound known for its multifaceted biological activities, including antifungal, anticancer, and antioxidant properties. This compound effectively inhibits key enzymes such as reverse transcriptase, protein-tyrosine kinase, and xanthine oxidase, contributing to its anti-HIV and anti-arteriosclerotic effects. Additionally, Morin 3-O-β-D-glucopyranoside exhibits superoxide scavenging capabilities, making it a valuable tool for research in cancer, virology, and oxidative stress. -
Triterpenoid
Melliferone is a triterpenoid derived from Brazilian propolis, known for its potential anti-inflammatory and antioxidant properties. It has been shown to exhibit biological activities that may influence immune response and cellular signaling pathways. Melifirone is utilized in research exploring therapeutic applications in inflammation and oxidative stress-related conditions. -
Pyrrole Alkaloid
Baculiferin A is a DOPA-derived pyrrole alkaloid primarily isolated from the Chinese marine sponge Iotrochota baculifera. This compound exhibits notable anti-HIV activity, making it a valuable tool for research in virology and potential therapeutic applications. Its unique chemical structure and biological properties provide opportunities for the investigation of novel antiviral strategies. -
Antiviral agent
Suksdorfin is an antiviral agent extracted from the fruits of Lomatium suksdorfii. This compound demonstrates activity against HIV-1, indicating its potential use in the study of antiviral therapies and HIV-related research. Its unique mechanism may offer insights into novel treatments for viral infections. -
Nature Product
Lancifodilactone F is a natural product isolated from the leaves and stems of Schisandra lancifolia. This compound exhibits significant anti-HIV activity with an EC50 of 20.69 μg/mL, demonstrating potential as a therapeutic agent. Additionally, Lancifodilactone F shows cytotoxic effects on C8166 cells, with a CC50 greater than 200 μg/mL, making it relevant for cancer research applications. -
Natural Compound
Swietemahalactone is a natural compound derived from Swietenia mahagoni, primarily known for its antibacterial properties. This compound demonstrates significant activity against Escherichia coli, making it a valuable tool for microbiological research. Swietemahalactone may be utilized in studies investigating natural antimicrobial agents and their potential therapeutic applications. -
Alkaloid
(-)-Codonopsine is an alkaloid known for its antibacterial properties, specifically targeting Gram-positive bacteria, including *Staphylococcus aureus*. This compound is valuable for research applications focused on bacterial infections and the development of new antibacterial agents. Its unique mechanism makes it a relevant tool in the study of antimicrobial resistance and therapeutic interventions. -
Carbazole Alkaloid
3,4-Dimethoxy-1,2-dimethyl-9H-carbazole is a carbazole alkaloid that serves as an important precursor in the synthesis of baccamycin. This compound demonstrates noteworthy biological activity, contributing to research focused on the development of antimicrobial agents and the exploration of alkaloid biosynthesis pathways. Its unique structural properties make it valuable in chemical research and medicinal chemistry applications.

