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Natural Compound
trans-Coniferyl aldehyde is a natural compound primarily recognized for its role in modulating gene expression related to UV stress. At a concentration of 1.20 μM, it suppresses 63% of UV-induced mutagenic gene expression, demonstrating an ID50 value of 0.76 μM. This compound exhibits significant antimutagenic activity against various agents, including furylfuramide and Trp-P-1, making it valuable for research in cellular protection and mutation prevention. -
Isoprenoid Flavonoid
Kushenol B is an isoprenoid flavonoid derived from S. flavescens that exhibits notable antimicrobial, anti-inflammatory, and antioxidant properties. It functions primarily by inhibiting cAMP phosphodiesterase (PDE), demonstrating an IC50 value of 31 µM. This compound is valuable for research involving cellular signaling, inflammation pathways, and oxidative stress. -
Natural Product
Hellicoside is a natural product derived from plantain, known for its inhibitory activity against cAMP phosphodiesterase and 5-lipoxygenase. Its modulation of these enzymes makes Hellicoside a valuable tool in studying intracellular signaling pathways and inflammation. This compound is applicable in various research areas, including pharmacology and biochemistry, particularly in exploring therapeutic strategies for diseases related to altered cellular signaling and inflammatory responses. -
Alkaloid
Mesembranol is a mesembrine-type alkaloid and a selective serotonin reuptake inhibitor, primarily targeting serotonin transport mechanisms. It is derived from Sceletium tortuosum and additionally exhibits inhibition of phosphodiesterase 4 (PDE4). This compound plays a significant role in the psychoactive effects associated with Sceletium tortuosum and is utilized in research focused on central nervous system disorders. -
Natural Products
Natsudaidain is a polymethoxyflavone derived from Citrus plants, specifically known for its ability to inhibit tumor necrosis factor-α and cyclooxygenase-2 production. This inhibition occurs through the suppression of p38 MAPK phosphorylation in mast cells, positioning Natsudaidain as a valuable reagent in anti-inflammatory research and potential therapeutic applications. Its unique biochemical properties make it a noteworthy compound for studies exploring the modulation of inflammatory pathways. -
isoquinoline alkaloid
Antidesmone is an isoquinoline alkaloid derived from Antidesma membranaceum, known for its ability to inhibit the activities of MAPK and NF-κB pathways. This compound demonstrates significant potential in preventing acute lung injury in vivo, making it valuable for research into inflammatory diseases and related therapeutic interventions. Its mechanistic insights can facilitate studies aimed at understanding the pathophysiology of lung injuries and exploring novel treatment strategies. -
Phenolic Compound
Isosalvianolic acid C is a phenolic compound derived from Lavandula angustifolia Mill. It exhibits significant antioxidant activity, making it a valuable reagent for research into oxidative stress and related cellular mechanisms. This compound is suitable for studies focused on its protective effects against cellular damage and its potential therapeutic applications. -
Indole alkaloid, Pisolithus tinctorius
Hypaphorine is an indole alkaloid derived from Pisolithus tinctorius, known for its potential neurological and glucose-lowering effects. This compound exhibits protective properties against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by downregulating the proinflammatory response. It effectively inactivates the p38/JNK signaling pathway through the upregulation of dual specificity phosphatase 1 (DUSP1), making it a valuable tool for studying inflammatory processes and metabolic disorders. -
Pyrrole Alkaloid
Debromohymenialdisine, a pyrrole alkaloid, demonstrates moderate inhibitory activity in the Raf/MEK-1/MAPK signaling cascade with an IC50 value of 881 nM. This compound is valuable for research into cellular proliferation and differentiation processes, contributing to a better understanding of signaling pathways and their implications in various biological contexts. Its potential applications extend to oncology and developmental biology studies. -
Substrate For ALDH, Precursor Compound for Phenolic Compounds
3-Hydroxybenzaldehyde serves as a substrate for aldehyde dehydrogenase (ALDH) and acts as a precursor for diverse phenolic compounds, including Protocatechuic aldehyde. This compound exhibits vasculoprotective properties, demonstrating potential in both in vitro and in vivo studies. Research applications primarily focus on its role in atherosclerosis, making it a valuable reagent for biochemical investigations related to cardiovascular health. -
Diterpenoid Quinone
Dehydromiltirone is a diterpenoid quinone that exhibits significant anti-inflammatory properties. It modulates the MAPK and NF-κB signaling pathways, thereby preventing liver injury and reducing neuroinflammatory responses. Additionally, Dehydromiltirone has been shown to inhibit platelet aggregation and is relevant for research applications in osteoporosis. -
Anthraquinone Dye
Reactive Blue 19 is an anthraquinone dye that primarily targets textile materials for coloration. This compound exhibits strong staining properties and is commonly used in both research and industrial applications for dyeing textiles and other substrates. Its vibrant hue and stability make it a valuable reagent in studies related to dye chemistry and material science. -
Anthraquinone Vat Dye
Vat Yellow 4 is a synthetic anthraquinone vat dye that functions through the formation of soluble dye intermediates, allowing for efficient coloration. This compound exhibits strong affinity towards cellulose fibers, making it suitable for dyeing cotton, rayon, and wool. Vat Yellow 4 is widely employed in the textile industry for producing vibrant and long-lasting colors in various textile applications. -
Anthraquinone Dye
Cibacron Blue 3G-A is an anthraquinone dye known for its ability to inhibit R46 β-lactamase with a Ki value of 1.2 µM. This compound demonstrates significant biological activity as an enzyme inhibitor and is valuable in research applications focused on antibiotic resistance mechanisms and β-lactamase function. Its inhibitory properties make it a useful tool for studying bacterial resistance and developing new therapeutic strategies. -
Anthraquinone Dye
Reactive Blue 4 sodium is an anthraquinone dye that acts as a colorimetric chemosensor, facilitating the sequential determination of multiple analytes based on their optical responses in aqueous solutions. This compound demonstrates key biological activity in various analytical applications, making it valuable for environmental monitoring, biochemical assays, and dye-sensitized solar cells research. Its specificity and sensitivity to different analytes enhance its utility in both laboratory and industrial settings. -
Anthraquinone Dye
Disperse Blue 60 is an anthraquinone dye recognized for its application in textile coloration. Its primary mechanism involves interaction with fibers, imparting vibrant blue hues to a variety of fabrics. This compound is utilized in research related to dye chemistry, textile engineering, and environmental monitoring, contributing to studies on dye degradation and its effects on ecosystems. -
Fluorescent Unnatural Amino Acid
L-ANAP TFA is a fluorescent unnatural amino acid (Uaa) that is genetically encodable and exhibits polarity-sensitive fluorescence characteristics. It is utilized in protein labeling and imaging applications, allowing for the study of protein dynamics and interactions in live cells. This reagent facilitates advanced research in protein engineering and biosensing, providing insights into cellular processes at the molecular level. -
Disaccharide Linker
Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering. -
Natural Product
2,4-Dihydroxy-3-methoxyacetophenone is a natural product with potential antioxidant properties. This compound is commonly utilized in biological research to investigate its effects on cellular processes and to evaluate its role in various biochemical pathways. Its unique structure and functional groups may provide insights into mechanisms of action relevant to pharmacology and medicinal chemistry. -
Triterpenoid
Cyclocarin A is a triterpenoid compound isolated from the leaves of Cyclocarya paliurus. This compound exhibits weak inhibitory activity against several enzymes, including α-glucosidase, lipase, DPP-IV, and aldose reductase, along with limited effects on human cancer cell lines (IC50 > 10 μM). Despite its modest biological activity, Cyclocarin A may serve as a useful tool for research in enzyme inhibition and cancer biology. -
Lignan Glucoside
(+)-Medioresinol Di-O-β-D-glucopyranoside is a lignan glucoside that acts as a potent inhibitor of 3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterase. This compound is of significant interest in biomedical research due to its potential to modulate cyclic AMP signaling pathways, which are crucial for various physiological processes. It is applicable in studies related to cellular signaling, pharmacology, and the development of therapeutic agents targeting cyclic AMP-related disorders. -
Alkaloid
β-Carboline-1-carboxylic acid is a β-carboline alkaloid that acts as an inhibitor of phosphodiesterase and indoleamine 2,3-dioxygenase, demonstrating an IC50 of 96 µM for cAMP phosphodiesterase. It exhibits significant biological activities including anti-inflammatory, antifibrotic, antitumor, and antibacterial properties, with cytotoxic effects on tumor cells. Furthermore, this compound inhibits inflammation via the NF-κB/p65 pathway and reverses epithelial-mesenchymal transition (EMT). It also shows potent antibacterial effects against Staphylococcus aureus and Escherichia coli, with IC50 values of 47.70 μg/mL and 19.17 μg/mL, respectively. -
Flavonoid Compound
Camellianin B is a flavonoid compound that serves as a metabolite of Camellianin A. This compound exhibits antioxidant properties and inhibits the activity of angiotensin-converting enzyme (ACE). Camellianin B is valuable in research related to oxidative stress and cardiovascular health, providing insights into the modulation of enzyme activity and potential therapeutic applications. -
Angiotensin-converting Enzyme (ACE)
Moveltipril calcium is an orally active inhibitor of angiotensin-converting enzyme (ACE), demonstrating significant antihypertensive effects. It forms a stable thioester bond, exhibiting relative resistance to hydrolysis in liver homogenates. Moveltipril calcium effectively inhibits ACE activity extracted from rabbit lung in a concentration-dependent manner. Additionally, it selectively inhibits the contractile response to angiotensin-I in rat aortic rings and guinea pig ileum preparations, while enhancing the response to calcitonin, making it valuable for research in cardiovascular pharmacology and hypertension. -
Flavonoid
Myricetin 3-O-α-L-arabinopyranoside is a flavonoid known for its antioxidant properties and protective effects against cellular damage. This compound demonstrates antibacterial and antiurease activities, along with the ability to inhibit A2E photooxidation-induced death of retinal pigment epithelial (RPE) cells. Its protective role against retinal degeneration and blue light-induced damage makes it a valuable reagent for research in ophthalmology and cellular stress responses. -
Isoprenoid Quinone
Coenzyme Q8 (Ubiquinone 8) functions as an isoprenoid quinone, facilitating electron transfer in the aerobic respiratory chain and mitigating oxidative stress. This compound supports bacterial respiratory function and fortifies host defense mechanisms against bacterial infections. Additionally, Coenzyme Q8 enhances macrophage phagocytosis and promotes the proliferation of antibody-producing cells. It is a valuable reagent for research in infectious diseases. -
Phenol Derivative
4-Chloroguaiacol (4-Chloro-2-methoxyphenol) is a phenol derivative known for its antimicrobial properties. This compound exhibits significant inhibitory effects against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations (MICs) of 110 μg/mL for both bacteria. It serves as a valuable tool for research in microbiology and antimicrobial susceptibility studies. -
Pyrrolizidine Alkaloid
Senecivernine is a pyrrolizidine alkaloid derived from various Senecio species. This compound is characterized by its weak mutagenic properties, making it a valuable tool for studying the effects of pyrrolizidine alkaloids on genetic stability. Additionally, Senecivernine has applications in toxicological research, providing insights into the molecular mechanisms of mutagenesis and potential health risks associated with alkaloid exposure. -
Natural Products
17-Hydroxyneomatrine is a natural product derived from Sophora flavescens, primarily known for its potential to inhibit the growth of human cervical carcinoma Hela cells. This compound displays a wide array of biological activities, including antibacterial, anti-allergic, anti-tumor, anti-arrhythmic, and diuretic effects. It is also recognized for its immunomodulatory and regulatory functions, making it a valuable reagent for research applications in cancer biology, immunology, and pharmacology. -
Natural Compound
Chaetoglobosin C is a natural anthraquinone-chromone compound isolated from the fungus Chaetomium globosum KMITL-N0802. This compound exhibits significant anti-tuberculosis activity, making it a valuable tool for research focused on tuberculosis treatment and drug discovery. Its unique biochemical properties provide opportunities for further studies in the development of new therapeutic agents against mycobacterial infections. -
Natural Compound
Multiflorin A is a natural compound derived from Pruni semen, known for its laxative activity. This reagent functions by inhibiting intestinal glucose absorption while promoting bacterial metabolism. Multiflorin A is applicable in research focusing on gastrointestinal health, metabolic disorders, and the effects of natural compounds on digestive processes. -
Antimicrobial Alkaloid
Glycozolidal is a carbazole alkaloid known for its antimicrobial properties, specifically targeting Porphyromonas gingivalis. This compound demonstrates significant cytotoxicity against human gingival fibroblasts and U937 monocyte cell lines, with IC50 values of 120.86 µg/mL and 97.74 µg/mL, respectively. Glycozolidal is a valuable tool for research applications focusing on bacterial infections and oral health. -
Natural Extract
Nepeta cataria extract is a natural extract known for its antioxidant and antimicrobial properties. This compound exhibits significant biological activity, making it relevant for research applications in health products. Its potential in promoting health and wellness through its bioactive components supports further investigation in various biomedical studies. -
Dehydroaporphine Alkaloid
N-Demethyl-N-formyldehydronuciferine is a dehydroaporphine alkaloid known for its mutagenic properties. It has been shown to induce mutations in the bacterial strains Salmonella typhimurium TA98 and TA100, making it a valuable tool in genetic research and mutagenesis studies. This compound is used to investigate the mechanisms of mutagenesis and assess the genotoxicity of various substances. -
Alkaloid
Coulteropine is a natural alkaloid that exhibits significant antimicrobial activity. Its mechanism of action involves disrupting microbial cell function, making it a valuable reagent for studying microbial resistance and infection models. Coulteropine is particularly useful in research applications focused on evaluating the efficacy of antimicrobial compounds and exploring potential therapeutic avenues in infectious diseases. -
Natural Extract
Garcinia mangostana extract is a natural extract from the fruit of the mangosteen tree, primarily featuring xanthones as its active compounds. This extract exhibits significant antioxidant, anti-inflammatory, and antimicrobial activities, making it a valuable addition to research focused on cellular protection and inflammation modulation. It is commonly utilized in studies exploring the therapeutic potential of natural compounds in various health applications. -
Natural Extract
Glycyrrhiza glabra extract primarily targets cellular stress responses through its bioactive compounds, including glycyrrhizic acid and flavonoids. This natural extract exhibits significant antioxidant, anti-inflammatory, antibacterial, and skin-protective properties. It is widely used in research applications focused on dermatological studies, inflammation modulation, and natural product pharmacology. -
Natural Extract
Hibiscus sabdariffa extract is a natural extract rich in anthocyanins, flavonoids, vitamin C, and organic acids like citric acid and malic acid. This extract exhibits significant antioxidant, anti-inflammatory, antibacterial, and antiviral properties, making it valuable for various research applications. Its diverse biological activities support studies in phytochemistry, nutrition, and therapeutic development. -
diterpene alkaloids
Spiramine A is a diterpene alkaloid that exhibits significant antitumor and antimicrobial properties. It effectively inhibits platelet aggregation induced by platelet-activating factor (PAF) in rabbit models, demonstrating a concentration-dependent response with an IC50 value of 6.7 μM. This compound is valuable for research applications focused on cancer biology and hematological studies. -
Flavonoids
Kushenol W is a prenylated flavonoid derived from the root of Sophora flavescens, targeting various biological pathways through its flavonoid structure. This compound exhibits antimicrobial activity, demonstrating a minimum inhibitory concentration (MIC) of 10 μg/mL against Staphylococcus aureus. It is suited for research applications involving microbial resistance and the exploration of flavonoid effects in pharmacology. -
Natural Extract
Piper longum extract is a natural botanical extract known for its diverse bioactive components, including piperine and piperidine. This extract exhibits potent anti-inflammatory, antioxidant, and antibacterial properties, making it valuable for various biochemical and pharmacological research applications. Additionally, it supports digestive health, making it an important subject for studies focused on gastrointestinal health and herbal medicine efficacy. -
Triterpenoid Saponin
Primulic acid I, a monodesmoid triterpenoid saponin, is derived from plant sources. This compound exhibits notable biological activity, including potential cytotoxic and anti-inflammatory effects. It serves as a valuable tool in various research applications, particularly those investigating plant-derived saponins and their pharmacological properties. -
Natural Extract
Emblic extract is a natural extract derived from the fruit of Phyllanthus emblica, a tree indigenous to India. Its active components, including vitamin C, tannins, flavonoids, polyphenols, and gallic acid, contribute to its potent antioxidant, anti-inflammatory, and antibacterial properties. This extract is widely utilized in research focused on oxidative stress, inflammation modulation, and microbial inhibition, making it valuable for studies aimed at developing therapeutic agents in various biological contexts. -
Natural Extract
Catnip fluid extract is a natural extract that exhibits notable antimicrobial and antioxidant properties. This essential oil is primarily investigated for its potential applications in therapeutic and research settings, where it can be utilized to explore its effects on microbial growth and oxidative stress. Its unique chemical composition makes it a valuable subject for studies related to herbal medicine and natural product chemistry. -
Natural Extract
Celery Extract, obtained from the seeds of Apium graveolens, primarily functions as a natural extract rich in bioactive compounds, including flavonoids and phenolic acids. This extract exhibits significant antihypertensive, anti-inflammatory, antimicrobial, and antioxidant activities, making it valuable in both traditional and contemporary medicine for managing hypertension and inflammation. In addition to its health-related applications, Celery Extract is employed in the food industry for flavor enhancement and in cosmetic formulations for its skin-protective and soothing properties. A patch test is advised to assess individual sensitivity. -
Natural Extract
Rosmarinus officinalis leaf extract is a natural extract primarily recognized for its antioxidant and anti-inflammatory properties. This extract exhibits antibacterial activity and has been shown to enhance cognitive function, making it valuable in neurological research. Key active components include rosmarinic acid, caryopsisic acid, caryopsisol, and various flavonoids, which contribute to its diverse biological effects. This extract is suitable for studies focused on oxidative stress, inflammation, and neuroprotective applications. -
Natural Products
Filicenol B is a natural product isolated from the whole plant of Adiantum lunulatum. It exhibits significant antibacterial activity, making it valuable for research in microbial studies and the development of antimicrobial agents. This compound serves as a useful tool in exploring alternative therapies and understanding the bioactive properties of plant-derived substances. -
Natural Product
D-Heptamannuronic acid, a natural product derived from marine brown algae and select Gram-negative bacteria, functions as an important alginate oligomer. This compound exhibits potential biological activity relevant to pain modulation and has applications in research related to vascular dementia. Its unique properties make it a valuable tool for investigating the underlying mechanisms of these conditions. -
Natural Extract
Terminalia chebula extract is a natural extract derived from the fruit of the Terminalia chebula tree, primarily rich in bioactive compounds such as tannins, flavonoids, and gallic and ellagic acids. This extract exhibits a broad spectrum of pharmacological activities, including antioxidant, anti-inflammatory, and antibacterial effects, effectively targeting pathogens like Helicobacter pylori, Staphylococcus aureus, and Escherichia coli. Additionally, it provides hepatoprotective and nephroprotective benefits, improving liver and kidney health through its modulatory effects on inflammatory pathways. Terminalia chebula extract also demonstrates neuroprotective activity and exhibits potential anti-diabetic properties by enhancing glucose uptake and mitigating oxidative stress. -
Natural Extract
Bambusa arundinacea extract is a natural extract known for its rich composition of bioactive compounds, including flavonoids, phenolic acids, and lignans. This extract exhibits significant antioxidant, anti-inflammatory, and antibacterial activities, making it valuable for various biological research applications. Its potential therapeutic benefits may be explored in studies related to oxidative stress, inflammation, and microbial infections.

