Catalog No.
Product Name
Application
Product Information
Citations
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Natural Extract
Gloriosa superba seed extract is a natural extract featuring a variety of bioactive compounds, including alkaloids such as colchicine and gloriosine. This extract exhibits significant analgesic, antibacterial, and antifungal activities, making it valuable for research in pain management and antimicrobial study. Its unique composition offers potential applications in pharmacological investigations and the development of therapeutic agents. -
Phenolic Glucose Glycoside Compound
Anol glucoside is a phenolic glucose glycoside compound derived from Cleidion spiciflorum. This compound exhibits significant antibacterial, anti-inflammatory, and antimalarial activities, making it a valuable tool for research in infectious diseases and inflammatory conditions. Its diverse biological properties highlight its potential for further investigation in both pharmacological and therapeutic applications. -
Natural Extract
Basil oil is a natural extract known for its significant antimicrobial and antioxidant properties. Rich in bioactive compounds such as eugenol and linalool, it effectively inhibits the growth of bacteria and fungi. This oil is widely utilized in biomedical research to investigate its therapeutic potential and to explore its applications in various health-related studies. -
Disaccharide
D-(+)-Trehalose, an α,α-disaccharide, serves as an effective osmolyte and stress protectant with significant anti-desiccant and cryopreservative properties. This compound is particularly useful in studies related to cellular protection under stress conditions and the transport and storage of carbon. D-(+)-Trehalose is applicable in various research contexts, including food science and pharmaceutical formulation. -
Natural Product
Inosinic acid is a natural metabolite that primarily enhances Umami flavor perception. It plays a significant role in improving the quality and yield of meat products, particularly in livestock such as pigs. Its applications in research extend to studying metabolic pathways and dietary influences on animal growth and product quality. -
Natural Product
D-Erythrose 4-phosphate sodium is a phosphorylated sugar derivative derived from erythrose. It plays a crucial role in cellular metabolism, particularly in the biosynthesis of aromatic amino acids through the shikimic acid pathway. This reagent is widely utilized in biochemical research to study metabolic pathways and enzyme mechanisms involving sugar phosphates. -
Phenolic Aldehyde
Vanillin, a phenolic aldehyde, serves as a versatile building block in chemical research. It is known for its antioxidant properties and is widely used in studies investigating flavor enhancement, fragrance applications, and potential health benefits. Additionally, vanillin has been utilized in the synthesis of diverse compounds, making it valuable in both organic chemistry and pharmaceutical research. -
Phenoloxidase Inhibitor
Phenylthiourea, a phenoloxidase inhibitor, effectively blocks the enzymatic oxidation of DOPA with a Ki value of 0.21 μM. This compound is recognized as a potent inhibitor of tyrosinase, making it valuable in research focused on melanin synthesis and pigmentation processes. Its use can result in observable physiological effects, such as the graying of hair in black rats, highlighting its impact on melanin formation. Phenylthiourea is essential for studies investigating the roles of phenoloxidase and tyrosinase in various biological systems. -
Fucoidan Oligosaccharide Substrate
GDP-L-fucose is a nucleotide sugar that serves as a crucial substrate for the biosynthesis of fucosylated oligosaccharides. It provides the fucose moiety necessary for the assembly of these complex carbohydrates. This compound is synthesized via two distinct pathways: the predominant de novo metabolic route and a secondary salvage pathway. Research has indicated a correlation between GDP-L-fucose levels and diabetes in rat models, highlighting its importance in metabolic studies and potential applications in glycobiology. -
Protein Denaturant/Nucleases Inhibitor
Guanidine thiocyanate is a potent protein denaturant and a strong inhibitor of nucleases. It serves as an effective nucleic acid protector during the extraction of DNA and RNA from cellular materials. This compound is widely utilized in buffers designed for nucleic acid isolation applications, ensuring the integrity and yield of extracted genetic material. -
Furan Terpenoid
(+)-Menthofuran is a furan terpenoid identified in various mint oils. It exhibits notable biological activity and serves as a valuable tool in studies related to flavor and fragrance compounds, as well as in evaluations of its potential therapeutic properties. Research on (+)-Menthofuran may contribute to advances in phytochemistry and natural product development. -
Natural Product
Dihydrosesamin is a lignan derived from the young shoots of Chamaecyparis obtusa cv. Breviramea. This natural product exhibits potential antioxidant properties and may play a role in cellular protection against oxidative stress. It is primarily utilized in research investigating the bioactivity of lignans, as well as their applications in pharmacological studies and natural product chemistry. -
Alkaloid Glycoside
Vicine is an alkaloid glycoside primarily derived from fava beans, known for its role in inducing toxicity in those with a hereditary deficiency in glucose-6-phosphate dehydrogenase. Upon ingestion, vicine is metabolized by intestinal microflora into its active form, divicine, a highly reactive compound that can lead to hemolytic anemia. This compound is essential in studies investigating metabolic disorders and hemolytic conditions. -
Metabolite of Pterostilbene
Pinostilbene is a natural metabolite of Pterostilbene, primarily known for its potential anti-cancer properties. It has demonstrated inhibitory effects on colon cancer cells, making it a valuable compound for cancer research. Pinostilbene's activity may provide insights into cancer treatments and the mechanisms of cell proliferation and apoptosis in colon cancer. -
α-Oxoaldehyde
Glyoxal is a cytotoxic α-oxoaldehyde known for its ability to induce cellular damage and promote protein glycation, leading to the formation of advanced glycation end-products (AGEs). This reagent is particularly relevant for investigating oxidative stress-related diseases, including atherosclerosis, cataracts, and Alzheimer's disease. Additionally, Glyoxal serves as a key compound in research related to the formation of calcium oxalate kidney stones. -
Alkaloid
8-Oxoepiberberine is an alkaloid known for its presence in plasma following the oral administration of Zuojin formula, a traditional Chinese medicine utilized for gastrointestinal disorders. This compound exhibits potential biological activity that may contribute to therapeutic effects on digestive health. Research applications may include exploring its role in gastrointestinal pharmacology and the examination of its metabolic pathways in herbal medicine contexts. -
Natural Product
Cyclosiversioside F 16,25-diacetate is a glycoside derived from the alkaline hydrolysis of its acetyl derivative. This natural product exhibits significant biological activity, making it a valuable compound for research in pharmacology and biochemistry. Its unique structure and properties facilitate investigations into potential therapeutic applications and the exploration of natural product chemistry. -
Polysaccharide
D-(+)-Cellotetraose is a polysaccharide consisting of four glucose units linked by β-1,4-glycosidic bonds. It serves as a primary hydrolysis product of cellulose, providing insights into cellulose degradation processes. This compound is useful in research applications involving enzymatic studies, carbohydrate metabolism, and the investigation of cellulose-derived oligosaccharides' biological functions. -
Alkaloid
11-Desethyl Irinotecan is a camptothecin (CPT) analog and a significant metabolite of irinotecan, targeting topoisomerase I. This compound exhibits potent antitumor activity and is instrumental in cancer research, offering insights into therapeutic applications and metabolism of CPT derivatives. Its pharmacological profile makes it a valuable tool for studying mechanisms of chemotherapy resistance and evaluating efficacy in various cancer models. -
Natural Product
(erythro) 1′,2′-Dihydroxyasarone is a natural product and a metabolite of Beta-asarone, which can be extracted from the roots of Acorus tatarinowii. This compound is known to form glucuronic acid conjugates in vivo, facilitating its excretion in urine. It serves as a valuable marker for studying the metabolism of Beta-asarone and assessing its potential toxic effects. -
Trastuzumab Signature Peptide
FTISADTSK is an endogenous stable signature peptide associated with Trastuzumab, serving as a valuable biomarker for monitoring therapeutic response. This peptide can be utilized in selected reaction monitoring (SRM) assays, facilitating quantitative analysis in oncology research. Its application extends to studies focused on trastuzumab treatment efficacy and patient stratification in breast cancer therapies. -
Natural Product
(25R)-12α-Hydroxyspirost-4-en-3-one is a natural product derived from Hecogenin through the metabolic action of Nocardia globerula. This compound exhibits potential biological activity relevant to the study of plant-derived steroids and their metabolic pathways. It is valuable for research applications focused on the characterization of steroid metabolites and their physiological effects. -
Prasugrel Impurity
Prasugrel chloride impurity is a chemical impurity associated with Prasugrel, extracted from patent US20130345428A1, line 0053. Prasugrel serves as a potent and orally active antagonist of the P2Y12 receptor, effectively inhibiting ADP-induced platelet aggregation. This reagent is useful for research applications related to platelet function and thrombotic disorders, aiding in the assessment of drug purity and compliance in pharmaceutical formulations. -
Natural Product
PD 109488 is a diketopiperazine metabolite derived from quinapril, functioning as a natural product. It exhibits significant biological activity that may be of interest in various research applications, particularly in the study of metabolic pathways and pharmacological profiles of peptide-based compounds. Its structural characteristics make it a valuable tool for exploring the biochemical mechanisms associated with diketopiperazine derivatives. -
Tobacco Alkaloid
(R,S)-Anatabine is a minor alkaloid derived from plants in the Solanaceae family, primarily associated with tobacco. It serves as a specific biomarker for the detection of tobacco consumption. Its biological activity is pivotal in studies focusing on tobacco-related research and the effects of nicotine exposure. -
Natural Plant Growth Regulator
Helminthosporol is a natural plant growth regulator primarily targeting the promotion of seedling development in rice and lettuce. Additionally, it demonstrates the ability to inhibit acyl-CoA: cholesterol acyltransferase (ACAT) activity in rat liver microsomes, thereby affecting cholesterol ester synthesis in macrophages. This compound is valuable for research applications focused on plant physiology and cholesterol metabolism. -
Natural Product
5-Methyl-5,6-dihydrouridine is a natural product that serves as a minor constituent of chromosomal RNA found in rat ascites tumors. This compound is applied in nucleic acid modification studies, facilitating research on RNA stability and structure. Its unique properties make it relevant for investigations into RNA processing and function in various biological contexts. -
Natural Product
Ganoderic acid T-Q is a natural product derived from Ganoderma lucidum, targeting tubulin polymerization. This compound has been shown to effectively stimulate the assembly of tubulin into microtubules, which are essential for cellular structure and function. Its properties make it a valuable tool in research applications focused on cytoskeletal dynamics and cellular processes. -
Natural Products
Symplostatin 1 is an analogue of Dolastatin 10, derived from the marine cyanobacterium Symploca hydnoides. This compound exhibits significant biological activity with potential applications in cancer research and drug discovery. Its unique structure and mechanism of action make it a valuable tool for investigating cellular processes and exploring natural product derivatives in pharmaceutical development. -
Fungal Alkaloid
Oxaline is a fungal alkaloid derived from Penicillium oxalicum that functions as a potent inhibitor of tubulin polymerization. This inhibition leads to cell cycle arrest at the M phase, making Oxaline a valuable tool for studying cellular processes and the effects of microtubule disruption in various biological systems. Its distinctive mechanism of action positions it as a useful reagent in cancer research and the exploration of novel antifungal therapies. -
Natural Product
p-Coumaroylputrescine is a natural product derived from the callus tissue culture of Nicotiana tabacum. It is known for its potential roles in plant defense mechanisms and stress response regulation. This compound can be utilized in research applications focused on plant physiology, metabolic pathways, and secondary metabolite biosynthesis. -
Triterpenoid
Lucidenic acid D is a highly oxidized triterpenoid that primarily targets inflammatory pathways. It exhibits significant anti-inflammatory and antiviral activities, effectively attenuating lipopolysaccharide-induced proinflammatory cytokine and nitric oxide release, while downregulating the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Additionally, Lucidenic acid D inhibits the expression of Epstein-Barr virus early antigen in TPA-treated Raji cells, demonstrating potential utility in cancer chemoprevention research. -
Quinazoline alkaloid
Dehydroevodiamine is a key bioactive quinazoline alkaloid derived from Evodiae Fructus, primarily known for its antiarrhythmic properties demonstrated in guinea pig ventricular myocytes. This compound effectively inhibits the expression of lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2), and nuclear factor-kappa B (NF-κB) in murine macrophage cells. Its diverse biological activities make it a valuable reagent for research focused on cardiovascular function and inflammatory responses. -
Homoisoflavonoid
3,9-Dihydroeucomin is a natural homoisoflavonoid that primarily targets cyclooxygenase enzymes. It exhibits potential biological activity with a focus on modulating COX-2 inhibition. This compound is useful for research applications investigating inflammatory pathways and can contribute to studies on pain management and related therapeutic strategies. -
Natural Compound
Pregomisin is a natural compound derived from the fruits of Schizandra chinensis Baill. It exhibits platelet-activating factor (PAF) antagonistic activity, with an IC50 value of 48 μM. This compound is valuable for research applications focused on inflammatory responses and cardiovascular health. -
Diterpenoid
Epi-cryptoacetalide is a natural diterpenoid that targets the estrogen receptor alpha (ER-α) and the prostaglandin E2 receptor EP2 subtype, demonstrating high affinity with Ki values of 0.3 μM and 1.92 μM, respectively. This compound exhibits anti-endometriosis activity, making it a valuable tool for research in reproductive biology and inflammatory conditions. Its modulatory effects on hormone receptors provide insights into potential therapeutic applications in endometriosis and related disorders. -
Alkaloid
(S)-Laudanosine is an alkaloid with a primary action on the central nervous system and cardiovascular system. It inhibits low-affinity GABA receptors, exhibiting an IC50 value of 10 μM and has the potential to induce seizures, hypotension, and bradycardia. Additionally, (S)-Laudanosine demonstrates analgesic properties through competitive binding to the opioid Mu-1 receptor, with a binding affinity characterized by a Ki value of 2.7 μM. This compound is valuable for research into neurological and cardiovascular functions. -
Signature Peptide
IYPTNGYTR is a deamidation-sensitive signature peptide derived from Trastuzumab, specifically designed to provide insights into the metabolic processes of this therapeutic antibody. Its detection allows for the monitoring of Trastuzumab metabolism in vivo, facilitating studies related to drug efficacy and stability. This peptide is valuable for researchers investigating antibody pharmacokinetics and therapeutic applications in oncology. -
Triterpenoid Compound
3β-Hydroxy-oleana-11,13(18)-dien-28-oic acid is a triterpenoid compound with potential anti-inflammatory and hepatoprotective properties. Isolated from Paeonia japonica and peony calli, this compound is recognized for its role as a biotransformation product of oleanolic acid. It may be applied in research focused on exploring natural products for therapeutic agents in various diseases. -
Natural Product
Aszonalenin is a natural product derived from the metabolite of Aspergillus zonatus. It exhibits significant antimicrobial activity and has been studied for its potential applications in antifungal and antibacterial research. Aszonalenin's unique biochemical properties make it a valuable compound for exploring natural product mechanisms and their therapeutic potential in infectious disease modeling. -
Sulfated phenolic acid
4-(Sulfooxy)benzoic acid is a sulfated phenolic acid that functions as a key metabolite in various biological systems, including C. elegans. This compound is derived from ethyl para-hydroxybenzoate and several flavonoids, playing a role in metabolic processes. It offers potential applications in research focused on metabolic pathways and the biological effects of phenolic compounds. -
Toxic Alkaloid
Jesaconitine is a toxic alkaloid primarily derived from Aconitum species. This compound serves as a significant metabolite detectable in the blood of the right atrium following aconitum poisoning. Jesaconitine is associated with various types of arrhythmia characteristic of aconitine intoxication, making it valuable for research into toxicological effects and mechanisms of cardiac dysrhythmias. -
Alkaloid N-oxide
(2'S)-Nicotine 1-oxide is an alkaloid N-oxide derived from Nicotiana tabacum, commonly known as tobacco. This compound serves as a significant metabolite and exhibits biological activity relevant for research in pharmacology and toxicology. Its applications include studies on nicotine metabolism, receptor interactions, and the exploration of its potential roles in neurobiology. -
Phenolic Metabolite
4-MeCat-2-sulfate is a phenolic metabolite that serves as a key biomarker for dietary polyphenol intake. This compound can be detected in plasma following the consumption of fruit puree, making it valuable for studies on dietary effects and metabolic processes related to fruit consumption. Its analysis can provide insights into human metabolism and the bioavailability of phenolic compounds. Researchers can utilize 4-MeCat-2-sulfate in investigations of dietary influences on health and disease. -
Mycophenolic acid metabolite
Mycophenolic acid acyl-β-D-glucuronide is a metabolite of Mycophenolic acid, primarily functioning through glucuronidation. It plays a crucial role in the pharmacokinetics of Mycophenolic acid, influencing its immunosuppressive efficacy. This compound is essential for studying drug metabolism and the therapeutic monitoring of immunosuppressive regimens in transplantation and autoimmune conditions. -
Crotonaldehyde Metabolite
Dicyclohexylammonium 3-hydroxy-1-methylpropylmercapturic acid is a metabolite of crotonaldehyde, an organic aldehyde primarily involved in various synthetic processes including the production of plastics, pharmaceuticals, and fragrances. This compound serves as a valuable marker for studying the metabolic pathways of crotonaldehyde exposure and is useful in toxicology research. Its application aids in elucidating the biochemical mechanisms through which crotonaldehyde may influence cellular functions and contribute to toxicological effects. -
Phenolic Acid
Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid with notable structural characteristics derived from Mahonia fortune. This compound serves as a valuable tool in chemical research, particularly for studies focused on phenolic compounds and their biological roles. While it does not exhibit NO inhibitory effects in vitro, it is an important component for understanding the diverse activities of phenolic acids in various biological contexts. -
Flavonoid
Sanggenon F is a flavonoid compound targeting adipocyte differentiation and nitric oxide production. It effectively inhibits the differentiation of 3T3-L1 adipocytes and reduces nitric oxide production in RAW264.7 cells induced by lipopolysaccharides and IFN-γ, with an IC50 of 19 nM. This compound holds potential for research applications in anti-inflammatory therapies and the management of metabolic diseases. -
Alkaloid
Isomaculosidine is an alkaloid derived from D. dasycarpus known for its ability to inhibit nitric oxide (NO) production. This compound exhibits significant anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated BV2 microglial cells, making it a valuable tool for studying neuroinflammatory processes. Its biological properties make it relevant for research applications focused on neurological disorders and inflammation. -
Natural Products
Multiflorin B is a kaempferol glycoside isolated from the root of the fern Neocheiropteris palmatopedata. It exhibits significant biological activity by inhibiting nitric oxide production, achieving a 52% reduction at a concentration of 20 µg/ml. This compound is valuable for research applications focused on natural products and the study of nitric oxide-related pathways in various biological systems.
