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IYPTNGYTR

Catalog No.: A70633
Signature Peptide
IYPTNGYTR is a deamidation-sensitive signature peptide derived from Trastuzumab, specifically designed to provide insights into the metabolic processes of this therapeutic antibody. Its detection allows for the monitoring of Trastuzumab metabolism in vivo, facilitating studies related to drug efficacy and stability. This peptide is valuable for researchers investigating antibody pharmacokinetics and therapeutic applications in oncology.
IYPTNGYTR 1431957-72-0 Signature Peptide
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Size Price Stock Qty
25mg
$1,275.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIYPTNGYTR is a deamidation-sensitive signature peptide derived from Trastuzumab, specifically designed to provide insights into the metabolic processes of this therapeutic antibody. Its detection allows for the monitoring of Trastuzumab metabolism in vivo, facilitating studies related to drug efficacy and stability. This peptide is valuable for researchers investigating antibody pharmacokinetics and therapeutic applications in oncology.
Product Information
Catalog NumA70633
FormulaC49H73N13O15
Molecular Weight1084.18
CAS Number1431957-72-0
Sequence shorteningIYPTNGYTR
SMILESCC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
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