Catalog No.
Product Name
Application
Product Information
Citations
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β-carboline Alkaloid
Dichotomine E is a β-carboline alkaloid derived from the root of Stellaria dichotoma var. lanceolata. This compound exhibits significant anti-inflammatory activity by inhibiting nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW264.7 cells. Its potential applications include exploring therapeutic strategies for inflammatory conditions and studying the biochemical pathways involved in inflammation. -
Natural Product
Methyl ganoderate H is a natural product derived from Ganoderma lucidum, known for its moderate inhibitory effect on nitric oxide (NO) production. This compound exhibits potential anti-inflammatory activity, making it a valuable tool for research investigating the modulation of inflammatory pathways. Its application may extend to studies involving neuroprotection and cancer biology, where nitric oxide plays a crucial role in cellular signaling. -
Anthraquinone
2,8-Dihydroxy-1-methoxyanthracene-9,10-dione is an anthraquinone known for its biological activity. It exhibits significant antioxidant and anti-inflammatory properties, making it valuable for research in pharmacology and natural product chemistry. This compound is commonly investigated for its potential therapeutic applications, particularly in the development of novel treatments based on traditional medicinal plants. -
Triterpenoid
Canophyllal is a triterpenoid compound isolated from the leaves of Elsholtzia ciliata. This compound exhibits weak inhibition of nitric oxide (NO) production, indicating potential anti-inflammatory properties. Canophyllal is useful in research investigating the modulation of immune responses and the role of NO in various biological processes. -
Natural Product
Angulasaponin B is a natural product derived from Vigna angularis. It primarily inhibits nitric oxide production in LPS-activated RAW264.7 macrophages, demonstrating IC50 values between 13 μM and 24 μM. This compound is valuable for research applications focused on macrophage activation, inflammation, and the modulation of nitric oxide synthesis. -
Sesquiterpenoid Compound
8-Epiasterolide is a sesquiterpenoid compound derived from the rhizomes of Atractylodes japonica Koidzumi. It functions as an inhibitor of nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW 264.7 macrophage cells. This compound is valuable for investigating the molecular mechanisms underlying inflammatory diseases and may serve as a potential lead for therapeutic development in related conditions. -
Cassane Diterpenoid
(+)-14-Deoxy-ε-caesalpin is a cassane diterpenoid that functions as a potent inhibitor of nitric oxide (NO) production. It effectively reduces NO release from RAW 264.7 macrophage cells stimulated by lipopolysaccharide (LPS). This compound is useful for studies focused on inflammatory responses and the modulation of nitric oxide signaling pathways in various biological contexts. -
Anti-inflammatory Triterpenoid
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid is an anti-inflammatory triterpenoid that effectively inhibits nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression in LPS-stimulated Raw264.7 macrophages. This compound is particularly relevant for research investigating the modulation of inflammatory pathways, making it a valuable tool for studies focused on inflammatory diseases and therapeutic development. Its mechanism of action supports exploration into potential anti-inflammatory therapies. -
Natural Product
Ac-wilforsinine N is a natural product derived from the dried root of Tripterygium wilfordii. This compound has been characterized for its biological activity, although it has shown to be inactive against nitric oxide production in cellular assays. Ac-wilforsinine N is primarily utilized in research focused on inflammatory diseases, contributing to the understanding of potential therapeutic applications in this area. -
Triterpenoid Compound
Bryonolic acid is a bioactive triterpenoid compound that exhibits potent immunomodulatory, anti-inflammatory, antioxidant, and anticancer properties. It is commonly employed in research focused on inflammatory diseases, cancer biology, and oxidative stress. Its diverse biological activities make it a valuable tool for investigating cellular signaling pathways and potential therapeutic applications. -
Diterpenoid
Floridolide B is a clerodane-type diterpenoid derived from the tuberous roots of Tinospora sagittata. This compound exhibits biological activity through the inhibition of nitric oxide (NO) production in LPS-stimulated microglia, with an IC50 value exceeding 60 μM. Its properties make Floridolide B a valuable reagent for research in neuroinflammation and related signaling pathways. -
NO Generation Inhibitor
Triptohypol E is a triterpenoid compound that serves as a nitric oxide generation inhibitor. It is extracted from the leaves of Rhododendron dauricum L. Triptohypol E effectively inhibits nitric oxide production in LPS-stimulated macrophages in a dose-dependent manner, making it a valuable reagent for research in inflammation and immune response. -
Nature Product
(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one is a natural product derived from the rhizomes of Curcuma kwangsiensis that functions as an inhibitor of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated macrophages. This compound exhibits an IC50 value of 8.93 μM, highlighting its potential as a research tool for studying inflammatory pathways. Its biological activity supports investigations into its therapeutic applications in conditions characterized by excessive NO production. -
Alkaloid
Circumdatin C is an alkaloid that demonstrates inhibitory effects on lipopolysaccharide (LPS)-stimulated nitric oxide production. Additionally, it inhibits acetylcholinesterase (AChE) activity with an IC50 value of 13.9 μM. This compound is valuable for research into neurodegenerative diseases, particularly Alzheimer's disease, by exploring mechanisms related to neurotransmitter regulation and neuroinflammation. -
NO Production Inhbitor
3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid is a triterpene extracted from Ganoderma lucidum that functions as a nitric oxide (NO) production inhibitor. It effectively reduces NO synthesis in BV-2 microglial cells activated by lipopolysaccharide (LPS), exhibiting an IC50 value of 4.15 μM. This compound is valuable for research applications related to neuroinflammation and the modulation of microglial activation. -
Natural Product
Valeriandoid B is an iridoid compound isolated from the roots of Valeriana jatamansi, a plant known for its traditional medicinal properties. This natural product exhibits various biological activities, including anti-inflammatory and antioxidant effects. Valeriandoid B is being studied for its potential applications in neuropharmacology and herbal medicine, offering insights into its therapeutic benefits on the nervous system. -
Alkaloid
Vomicine is a bioactive alkaloid that targets the cGAS-STING-TBK1 signaling pathway, demonstrating significant anti-inflammatory properties. Isolated from the seeds of Strychnos nux-vomica, vomicine is valuable for research in inflammation-related studies and may contribute to understanding immune responses. Its mechanism of action positions it as a potential candidate for exploring therapeutic interventions in inflammatory diseases. -
Natural Compound
Dehydroperilloxin is a natural compound derived from the dichloromethane extract of Perilla frutescens var. acuta. This compound exhibits potent inhibitory activity against cyclooxygenase-1, with an IC50 value of 30.4 μM. It is primarily utilized in research exploring anti-inflammatory pathways and the modulation of eicosanoid synthesis. -
Natural Product
3,4-Diphenyl-5H-furan-2-one is a natural product derived from the endophytic fungus Aspergillus flavipes AIL8, isolated from the mangrove plant Acanthus ilicifolius. This compound acts as a selective inhibitor of COX-2, demonstrating significant anti-inflammatory and analgesic properties. It serves as a valuable lead compound for research into therapies targeting inflammation and pain-related disorders. -
Flavonoid
Neosakuranin is a flavonoid that targets xanthine oxidase and cyclooxygenase-1 (COX-1), exhibiting a suppressive effect with an IC50 value of 157.8 μM. Isolated from Sorbus commixta and the bark of Prunus cerasus, Neosakuranin demonstrates potential anti-inflammatory activity. This compound is valuable for research in the field of inflammatory diseases, providing insights into its therapeutic potential. -
Natural Product
Picralinal, a triterpenoid compound, is primarily derived from the whole plants of Scilla scilloides. This natural product exhibits significant biological activity, making it valuable in various research applications, including pharmacological studies and investigation of its therapeutic potential. Its unique structural features and biological properties may facilitate the exploration of novel drug candidates derived from natural sources. -
Nitrogen Disaccharide
N-Acetyllactosamine is a nitrogen-containing disaccharide that serves as a galectin-3 inhibitor. It is an essential building block for various oligosaccharides found in glycoproteins and sialyl Lewis X. This compound is also valuable as a precursor in the synthesis of diverse oligosaccharides and exhibits prebiotic effects, making it relevant for research in glycomics and carbohydrate biology. -
Flavonoid Glycoside
Ternatumoside II is a flavonoid glycoside with the ability to stimulate the expression of interferon-gamma (IFN-γ). Isolated from Rhododendron crenulata, it exhibits notable radical-scavenging activities, demonstrating IC50 values of 260.5 μM and 320.2 μM for DPPH and ABTS assays, respectively. This compound is of interest in studies related to antioxidative defense and immune modulation. -
Alkaloid
2-Hydroxy-1-Methoxyaporphine is an alkaloid derived from Nelumbo nucifera, exhibiting significant biological activity. This compound has been identified as the principal active component of the traditional Chinese medicine Jiang-Zhi-Ning, highlighting its potential applications in pharmacological research and therapeutic development. Further investigations into its mechanisms of action may reveal new insights into its efficacy in various health conditions. -
Natural Product
Porsone is a cyclic diarylheptanoid derived from the roots of Myrica nana. This natural product exhibits significant biological activity, including anti-inflammatory and antioxidant properties. Its applications in research include the study of cellular signaling pathways and the exploration of therapeutic potential in various diseases, particularly for their role in modulating inflammation and oxidative stress. -
Corn Carrot
β-Zeacarotene is a naturally occurring zea carotene known for its vitamin A activity. This compound is primarily extracted from corn and carrots, playing a crucial role in photoprotection and antioxidant activity. Its applications extend to research in nutrition, functional foods, and the study of carotenoid metabolism. -
Oligosaccharide
NA2 Glycan is an asialo N-linked oligosaccharide that represents the core structure of A2 glycan. It can be isolated from mammalian serum glycoproteins, including serum IgG. This reagent is primarily used in glycan analysis and studies of glycoprotein biology, contributing to the understanding of glycosylation patterns and their implications in various biological processes. -
Natural Product
Physalin C is a natural product derived from Physalis angulata, exhibiting cytotoxic activity primarily against MCF-7 and HepG2 cancer cell lines. Its mechanism of action involves induction of apoptosis and inhibition of cell proliferation. This compound serves as a valuable tool for research in cancer biology and the exploration of natural compounds with potential therapeutic applications. -
Hepatotoxic Pyrrolizidine Alkaloid
Lasiocarpine is a hepatotoxic pyrrolizidine alkaloid known to induce fatal liver veno-occlusive disease in vivo. Its toxicity arises from metabolic conversion to harmful intermediates, such as dehydrolasiocarpine and N-oxide. Lasiocarpine is valuable for research focused on liver toxicity mechanisms and the effects of pyrrolizidine alkaloids in biological systems. -
Natural Product
3',4,4',6-Tetrahydroxyaurone 4-O-β-D-glucoside is a natural product classified as a chalcone glucoside. This compound exhibits various biological activities, making it valuable for pharmacological research. Its presence in Acacia dealbata highlights its potential applications in studies related to natural compounds and their therapeutic properties. -
Natural Products
Apigenin triacetate is a derivative of apigenin and serves as a natural product metabolite found in F. graminearum. This compound can be regulated through chitosan treatment, indicating its role in fungal biology and metabolism. Apigenin triacetate may be utilized in research focused on natural products and their interactions within various biological systems. Its potential applications also extend to studies examining fungal response mechanisms and secondary metabolite production. -
Triterpene Compound
15-Hydroxy-3,11,23-trioxolanost-8,20-dien-26-oic acid is a triterpenoid compound primarily extracted from Ganoderma lucidum. This compound exhibits significant biological activity, particularly in the modulation of cellular pathways related to inflammation and apoptosis. It is widely utilized in research focused on understanding its therapeutic potentials in cancer and immune-related diseases. Studies suggest its role in promoting health benefits through its bioactive properties. -
Natural Product
Jatrophane 4 is a diterpene, a secondary metabolite derived from Euphorbia peplus. It exhibits significant biological activity and is of interest in research for its potential applications in pharmacology and biochemistry. Studies have suggested that Jatrophane 4 may possess unique properties that can be explored for therapeutic development and the investigation of natural product interactions in various biological systems. -
α,β-unsaturated aldehyde
trans-4,5-Epoxy-(E)-2-decenal is an α,β-unsaturated aldehyde that plays a significant role in chemical signaling within mammalian systems. This compound is responsible for the distinctive metallic odor associated with blood, which predators utilize to locate potential prey. Its unique properties make it a valuable reagent for research into olfactory signaling and predator-prey interactions. -
Natural product
5-Bromo-DL-tryptophan is a natural product derived from Aspergillus fumigatus. This compound is primarily known for its incorporation into proteins and its role in biochemical pathways involving serotonin and melatonin synthesis. It has potential applications in research related to neurobiology, metabolic studies, and the investigation of tryptophan-derived metabolites and their effects on cellular functions. -
Indole Alkaloid
Deoxybrevianamide E is an indole alkaloid that functions as a biosynthetic precursor for various advanced metabolites derived from marine-derived Aspergillus species. This compound exhibits significant biological activity, making it a valuable tool for researching metabolic pathways and the biosynthesis of marine natural products. Its application in chemical biology can enhance the understanding of alkaloid structures and their functions. -
Polyketide Natural Product
Epothilone C is a polyketide natural product that functions as a microtubule stabilizer. It exhibits potent antitumor activity by inhibiting cancer cell proliferation and promoting apoptosis. Epothilone C is valuable in cancer research, particularly for studies focusing on microtubule dynamics and therapeutic applications in oncology. -
Natural Product
Quercetin 3,7-dimethyl ether is a natural product derived from Croton schiedeanus Schlecht, primarily targeting the NO/cGMP signaling pathway. This compound exhibits enhanced vasorelaxant activity, making it a valuable tool for research into vascular health and related physiological processes. Its unique properties support investigations into cardiovascular functions and potential therapeutic applications in hypertension and related disorders. -
Anthraquinone Derivative
9-Dehydroxyeurotinone is an anthraquinone derivative derived from Eurotium rubrum, known for its cytotoxic properties. It exhibits significant cytotoxicity against SW1990 cells, with an IC50 value of 25 µg/mL. This compound is valuable for research in cancer biology and may aid in the development of therapeutic strategies targeting tumor cells. -
Natural Product
(-)-Dihydrojasmonic acid is a natural product derived from the immature fruits of Vicia faba L. It functions as a plant endogenous cyclopentanoid metabolite, playing a critical role in various physiological processes. This compound is utilized in research applications focusing on plant biology and plant stress responses, providing insights into jasmonate signaling pathways and their effects on plant growth and development. -
Non-Sugar Components of Lipopolysaccharides
Alanopine is a non-sugar component of lipopolysaccharides derived from Providencia and Proteus species. It plays a critical role in bacterial membrane stability and may influence immune responses. Research applications include studies on bacterial pathogenesis and the role of lipopolysaccharides in host-pathogen interactions. -
Natural Products
(22E,24R)-Stigmasta-4,22-dien-3-one is a steroidal compound derived from natural sources, specifically isolated from sponges. This compound exhibits potential biological activity that may be valuable in various research applications, including the study of natural products and their medicinal properties. Its structural characteristics facilitate further investigation into its mechanism of action and therapeutic potential. -
Alkaloids
Nocarimidazole A is an alkaloid that exhibits ultraviolet activity and is derived from the marine actinomycete Nocardiopsis. This compound has potential applications in biological research due to its unique structural properties. Nocarimidazole A may be useful in studying the effects of alkaloids on cellular processes and exploring its therapeutic potential in various fields of bioscience. -
Psychoactive Alkaloid
(-)-Mesembrine is a psychoactive alkaloid primarily derived from Sutherlandia frutescens. This compound acts as a partial agonist at the serotonin receptor, contributing to its psychoactive effects. It has been investigated for its potential applications in mood enhancement and cognitive function research. Additionally, (-)-Mesembrine may offer insights into therapeutic strategies for mood disorders. -
Alkaloid
Thalicminine is an alkaloid derived from Thalictrum species, known for its respiratory stimulant properties. This compound exhibits a transient hypotensive effect in canine models and has been shown to extend the hypnotic effects of chloral hydrate in murine studies. Thalicminine serves as a valuable tool in pharmacological research, particularly in studies investigating respiratory and sedative mechanisms. -
Flavonoid
Calycopterin is a flavonoid compound sourced from the leaves of Digitalis thapsi, primarily known for its immunosuppressive properties. This compound has demonstrated potential in modulating immune responses, making it suitable for research applications related to immune diseases and therapeutic interventions. Its distinctive biological activity positions calycopterin as a valuable reagent for exploring the underlying mechanisms of immune regulation. -
Natural Product
2-Heptyl-4,6-dihydroxybenzoic acid is a naturally occurring compound derived from orcinol. This chemical is of interest in various biological studies due to its potential antioxidant properties and involvement in metabolic pathways. It serves as a valuable reagent for research applications focusing on natural products and their effects on biological systems. -
Sesquiterpenoid Compound
Siegesbeckiol is a sesquiterpenoid compound derived from Isodon flavidus. This natural product exhibits significant biological activity, primarily as an anti-inflammatory agent. It is commonly used in research focused on exploring its therapeutic potential and mechanisms of action in various biological systems. -
Natural Product
2-Nonyl alcohol is a natural product that acts as a metabolite derived from the fermentation of the strain PJ16. This compound exhibits potential biological activity relevant to various research applications, including studies on microbial metabolism and the exploration of biosynthetic pathways. As a versatile reagent, it can be utilized in the investigation of biotransformation processes and the development of green chemistry protocols. -
Natural Products
Dihydrosamidin is a coumarin derivative derived from the fruits of Ammi visnaga. This compound promotes neuroplasticity and modulates metabolic processes, including glycolysis and oxidative phosphorylation, while enhancing antioxidant defenses. Additionally, Dihydrosamidin has been shown to inhibit triacylglycerol accumulation in 3T3-L1 preadipocytes. Its biological activities make it valuable for research applications in neuroprotection and anti-obesity studies.
