8-Epiasterolide

Catalog No.: A65201
Sesquiterpenoid Compound
8-Epiasterolide is a sesquiterpenoid compound derived from the rhizomes of Atractylodes japonica Koidzumi. It functions as an inhibitor of nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW 264.7 macrophage cells. This compound is valuable for investigating the molecular mechanisms underlying inflammatory diseases and may serve as a potential lead for therapeutic development in related conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description8-Epiasterolide is a sesquiterpenoid compound derived from the rhizomes of Atractylodes japonica Koidzumi. It functions as an inhibitor of nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW 264.7 macrophage cells. This compound is valuable for investigating the molecular mechanisms underlying inflammatory diseases and may serve as a potential lead for therapeutic development in related conditions.
Product Information
Catalog NumA65201
FormulaC15H20O2
Molecular Weight232.32
CAS Number16641-51-3
SMILESC[C@]12[C@@](C(CCC2)=C)([H])CC([C@@](O3)([H])C1)=C(C)C3=O
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