Catalog No.
Product Name
Application
Product Information
Citations
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Alkaloid
(E/Z)-Piperine is an alkaloid known for its pungent characteristics. This compound exhibits a range of biological activities, including anti-inflammatory, immunomodulatory, and anti-cancer effects, along with antispasmodic and anti-secretory properties. Notably, (E/Z)-Piperine demonstrates significant neuroprotective effects in models of Alzheimer's disease and Parkinson’s disease, making it a valuable tool for research in neurodegenerative disorders. -
Natural Product
Wallichinine is a natural product derived from the twigs and leaves of Trigonostemon thyrsoideum, classified as a diterpenoid. It exhibits notable biological activities that may be useful in various research applications, particularly in studies focused on natural compounds and their pharmacological properties. Researchers may explore its potential effects on cellular processes and its applications in drug discovery. -
Natural Compound
Pepluanin A is a natural compound derived from Euphorbia peplus L., exhibiting potent inhibitory activity against P-glycoprotein (Pgp). This jatrophane diterpene demonstrates more than double the effectiveness of Cyclosporin A in inhibiting Pgp-mediated transport of Daunomycin. Its significant biological activity positions Pepluanin A as a valuable reagent for research involving drug resistance and pharmacokinetics. -
Phenolic Substance
Salviaplebeiaside is a phenolic compound isolated from the aerial parts of Vitex negundo var. cannabifolia. It functions as an inhibitor of class I P-glycoprotein, which plays a critical role in drug transport and metabolism. This reagent is valuable for research applications focused on drug resistance mechanisms and pharmacokinetics. -
Natural Compound
Jatrophane 5 is a natural compound derived from Jatropha carcas L., targeting P-glycoprotein (P-gp). It exhibits potent inhibitory activity against P-gp, surpassing that of R(+)-verapamil and Tariquidar in colorectal multi-drug resistant DLD1-TxR cells. This compound is valuable for research into overcoming multidrug resistance in cancer treatment and enhancing drug efficacy in resistant cell types. -
Diterpenoid alkaloid
Lappaconine is a diterpenoid alkaloid known for its potential role in biochemical research. It facilitates the α-hydroxylation of β-oxo esters, making it a valuable reagent for synthetic organic chemistry applications. Its unique chemical properties may also contribute to studies investigating biological pathways and therapeutic targets related to alkaloids. -
Natural Product
β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA) that plays a critical role in plant stress responses. This compound accumulates in the vacuole and the endoplasmic reticulum, allowing for the rapid release of free ABA under abiotic stress conditions such as dehydration and salinity. β-D-Glucopyranosyl abscisate is integral to maintaining ABA homeostasis, making it a valuable tool for research on plant physiology and stress signaling pathways. -
Aconitum Alkaloid
6-Benzoylheteratisine acts as an antagonist of tetrodotoxin and targets sodium channels, demonstrating potential neuroprotective activity. It effectively inhibits the influx of sodium ([Na+]i) and calcium ([Ca2+]i) ions, as well as the release of glutamate, making it relevant for the study of excitatory neurotransmission. Additionally, 6-Benzoylheteratisine has shown inhibitory effects on neuronal activity associated with epileptiform burst discharge, suggesting its utility in neurological research and potential therapeutic applications in epilepsy. -
Alkaloid
Muramine is an alkaloid derived from the bulbs of Corydalis decumbens. It functions primarily by inhibiting spontaneous Ca2+ oscillations, leading to a reduction in neuronal excitability, with an IC50 value of 13.5 μM. This compound is valuable for research exploring calcium signaling pathways and neuronal activity modulation. -
Indole Alkaloid
Hirsuteine is an indole alkaloid derived from Uncaria rhynchophylla, functioning primarily as a non-competitive antagonist of nicotinic acetylcholine receptors. This compound effectively inhibits nicotine-mediated dopamine release by obstructing ion permeation through receptor channel complexes. Hirsuteine is valuable for research focused on neuropharmacology and the modulation of dopaminergic signaling, particularly in studies related to addiction and neurodegenerative disorders. -
Benzyltetrahydroisoquinoline Alkaloid
(+)-Coclaurine hydrochloride is a benzyltetrahydroisoquinoline alkaloid extracted from various plant sources. This compound exhibits notable anti-aging activity and is utilized in research to explore its potential therapeutic effects. Its unique biological properties make it a valuable tool for studying the mechanisms of aging and related pathways. -
Alkaloid
(±)-Coniine is a piperidine alkaloid known for its function as an nAChR agonist, demonstrating an EC50 of 0.3 mM. This compound exhibits acute toxicity in murine models, with an LD50 value of 7.7 mg/kg. Its unique properties make it valuable for research applications focused on neuromuscular transmission and toxicity studies. -
Polymethoxyflavonoid
3',4',7-Trimethoxyquercetin is a polymethoxyflavonoid identified in Taraxacum mongolicum, and is recognized as a derivative of Quercetin hydrate. This compound exhibits notable anti-tumor activity, making it of significant interest in cancer research. Its potential applications include studies focused on the modulation of signaling pathways implicated in tumor growth and progression. -
Calmodulin Inhibitor
Encecalinol, a calmodulin inhibitor extracted from the aerial parts of Ageratina grandifolia, exhibits significant biological activity through the disruption of calmodulin-mediated signaling pathways. This compound serves as a valuable tool in the study of calcium-dependent processes and can aid in elucidating the roles of calmodulin in various cellular functions. Its application extends to research involving cardiovascular diseases, neurodegenerative disorders, and other conditions where calmodulin plays a critical role. -
Calmodulin Antagonist
Fasciculic acid A is a steroid compound identified as a calmodulin antagonist, extracted from the fungus Hypholoma lateritium. This reagent demonstrates significant anti-inflammatory properties, making it a valuable tool for research focused on calmodulin-related signaling pathways and associated disorders. Its unique activity profile supports various applications in biochemical studies and drug discovery efforts targeting calcium-mediated processes. -
Natural Products
α,β-Thujone is a monoterpene ketone derived from the essential oils of various plants. This compound exhibits a range of biological activities, including neurotoxic effects that can induce seizures at elevated doses. Research applications of α,β-Thujone include studies on its potential carcinogenic properties and its effects on the central nervous system, making it a valuable reagent for investigations into toxicity and pharmacology. -
Alkaloid
Guvacine ethyl ester is an alkaloid derived from the betel nut with a primary mechanism as a GABA uptake inhibitor. It plays a significant role in the modulation of neurotransmitter levels, making it a valuable compound for research on neurological disorders and pharmacological studies related to GABAergic signaling pathways. Its utility in synthetic chemistry further enhances its application in developing novel therapeutic agents targeting the central nervous system. -
Natural Product
Inactone is a natural product that targets the large ribosomal subunit, exhibiting potent inhibitory effects. This bioactive molecule features a unique 3-glutarimidyl group, making it a valuable tool for studying ribosomal function and protein synthesis. Its ability to modulate ribosomal activity positions Inactone as a crucial reagent for research in molecular biology and related fields. -
Active Alkaloid
Wilforgine is a bioactive sesquiterpene alkaloid extracted from Tripterygium wilfordii Hook. F, primarily targeting calcium receptors or channels in muscle tissues. This compound has been shown to induce significant microstructural and ultrastructural alterations in the muscles of Mythimna separata larvae, making it a valuable tool for research into muscle physiology and insect neurobiology. Its unique activity profile positions Wilforgine as a potential candidate for studies focused on muscle function and pharmacological modulation in insects. -
Diterpene Dialdehyde
(-)-α-Eudesmol is a diterpene dialdehyde known for its neuroprotective properties. It has demonstrated efficacy in mitigating acute brain injury induced by diethylnitrosamine. This compound is valuable in neurological research, particularly in studies focused on oxidative stress and its impact on neuronal health. -
Natural Product
15-Methoxypinusolidic acid is a labdane diterpene compound derived from the leaves of Calocedrus microlepic. This natural product exhibits significant biological activity, particularly in the modulation of cellular pathways. It is primarily utilized in research applications investigating its potential therapeutic effects and mechanisms of action in various biological systems. -
Natural Product
Texasin is a natural product derived from Baptisia australis, known for its potential biological activity. This compound has been studied for its effects in various biochemical research applications, including its role in modulating cellular processes and examining its effects on signaling pathways. Researchers may utilize Texasin to explore its therapeutic potentials and investigate mechanisms of action in relevant biological contexts. -
Antioxidant Flavonoid
Patulitrin is an antioxidant flavonoid that exhibits significant scavenging activity against DPPH radicals and inhibits soybean lipoxygenase, making it a valuable compound for oxidative stress research. Additionally, Patulitrin demonstrates antihypertensive properties, highlighting its potential therapeutic applications in cardiovascular health. This compound can be isolated from Anthemis tinctoria, furthering its relevance in phytochemical studies. -
Diterpenoid
6,7-Dehydroferruginol is a diterpenoid compound derived from the dichloromethane extract of Juniperus communis wood. This compound exhibits a specific profile in biological assays, as it does not inhibit 12(S)-lipoxygenase (12(S)-LOX) activity or the production of 12(S)-HETE at a concentration of 100 μg/mL. Its unique biochemical characteristics make it a valuable tool for research in lipid signaling pathways and enzyme activity modulation. -
Natural Product
Ethyl 2,4,6-trihydroxybenzoate is a natural product derived from Pueraria lobata, exhibiting notable triterpenoid properties. It serves as a valuable reagent for research investigating the biological activities and potential therapeutic applications of plant-derived compounds. This compound is utilized in studies focused on antioxidant and anti-inflammatory mechanisms, contributing to a deeper understanding of natural product chemistry. -
Bioactive Secoiridoid Derivative
Ligustroside, a bioactive secoiridoid derivative, primarily targets mitochondrial bioenergetics, demonstrating significant potential in models of early Alzheimer's disease and brain aging. Its mechanisms of action appear not to interfere with amyloid-beta production, making it a valuable compound for neurodegenerative research. Additionally, Ligustroside effectively inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages, highlighting its role in inflammatory responses. -
Flavonoid Compound
3,5,7-Trimethoxyflavone is a flavonoid compound that exhibits inhibitory action on TNF-α-induced expression and secretion of MMP-1 in cells. This compound is beneficial for research focusing on skin damage amelioration and has potential applications in dermatological studies aimed at understanding inflammation and extracellular matrix remodeling. -
Nature Product
3,3′-Bisdemethylpinoresinol is a naturally occurring lignan known for its ability to inhibit matrix metalloproteinase-1 (MMP-1) in UVA-irradiated human dermal fibroblasts. This compound is primarily isolated from the seeds of Morinda citrifolia and is of interest in research focused on skin aging and photodamage. Its biological activity may provide insights into therapeutic strategies for maintaining skin integrity in response to ultraviolet radiation. -
Napthoquinone
(Rac)-Arnebin 1 is a naphthoquinone compound derived from Arnebia nobilis, consisting of the racemic mixture of β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin. This compound exhibits notable anti-tumor activity, making it a valuable tool for cancer research. Its applications include investigating the mechanisms of action for therapeutic agents and exploring potential benefits in oncology studies. -
Flavonoid Compound
Averionol is a flavonoid compound that serves as a potential lead in the development of anti-HIV agents. Although it lacks significant inhibitory activity against HIV integrase, its structural properties may provide insights for further modifications and optimization in antiviral research. This compound is relevant for studying flavonoid effects in therapeutic contexts, particularly in the quest to enhance HIV treatment strategies. -
HMGCR Inhibitor
Ganoderenic acid K is a potent inhibitor of HMG-CoA reductase (HMGCR), demonstrating an IC50 value of 16.5 μM. This natural compound can be extracted from the fruiting bodies of Ganoderma lucidum. Ganoderenic acid K has significant implications in cholesterol regulation research and potential therapeutic applications in hyperlipidemia and cardiovascular diseases. -
Terpenoid
Lucidenic acid E is a terpenoid derived from Ganoderma lucidum, known for its bioactive properties. It exhibits significant anti-inflammatory and antioxidant activities, making it a valuable compound for investigating therapeutic applications in chronic diseases and aging-related disorders. Its unique chemical structure facilitates research into its potential effects on cellular signaling pathways and overall health benefits. -
Triterpenoid Saponin
Platycodin V is a triterpenoid saponin that primarily targets pancreatic lipase. It exhibits a weak inhibitory effect on this enzyme, making it relevant for studies on lipid metabolism and obesity. Researchers may utilize Platycodin V to explore its potential therapeutic applications or to investigate the biochemical pathways associated with lipid digestion and absorption. -
Lipase Inhibitor
Ligupurpuroside A is a competitive inhibitor of lipase, extracted from Ligustrum robustum. This compound demonstrates significant biological activity by modulating lipid metabolism and may be beneficial for research focused on obesity and metabolic disorders. Its inhibitory effects on lipase make it a valuable reagent for studies investigating lipid digestion and absorption. -
Natural Product
Altenusin is a natural product known for its potent DPPH radical scavenging activity. This compound exhibits antioxidant properties, making it a valuable reagent for research in oxidative stress and related biological systems. Altenusin is commonly used in studies investigating potential therapeutic applications in antioxidant defense mechanisms. -
Alkaloid
N-Caffeoyl O-methyltyramine is an alkaloid with demonstrated inhibitory activity against α-glucosidase, exhibiting an IC50 value of 103.58 μM. This compound is derived from Cuscuta reflexa and is relevant for research focused on glucose metabolism and diabetes. Its potential applications include studying carbohydrate absorption and metabolic disorders, making it a valuable reagent in biochemical investigations. -
Natural product
6-Prenylquercetin-3-Me ether is a natural product extracted from the leaves of Glycyrrhiza uralensis. It exhibits potent radical scavenging activity against DPPH, indicating its potential as an antioxidant. Additionally, this compound displays inhibitory activity against α-glucosidase, making it valuable for research in diabetes and metabolic disorders. -
Natural Product
5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl is a natural product isolated from Dendrobium infundibulum. This compound is primarily investigated for its potential biological activities, although it has been shown to lack inhibitory effects against α-glucosidase and pancreatic lipase. It serves as a valuable tool in research focused on understanding the pharmacological properties of natural compounds and their metabolic implications. -
Natural Product
Timosaponin N is a natural steroidal saponin that acts as an inhibitor of α-Glucosidase. Its primary mechanism involves reducing glucose absorption in the intestine, making it an important research tool in studies related to diabetes and glycemic control. Timosaponin N may provide insights into therapeutic pathways for managing blood sugar levels in diabetic patients. -
Natural Products
α-Glucosidase-IN-35 is a chromene that functions as a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 0.169 mg/mL. Isolated from the aqueous extract of the aerial parts of Brickellia cavanillesii, this compound is valuable in studies targeting carbohydrate metabolism and diabetes research. Its application may facilitate the exploration of α-glucosidase inhibition as a therapeutic strategy in metabolic disorders. -
Natural product
Sumaresinolic acid is a natural product extracted from the root of Heterophyllum species. Its primary mechanism involves the inhibition of alpha-glucosidase, an enzyme implicated in carbohydrate metabolism. This compound exhibits significant biological activity in regulating blood glucose levels, making it valuable for research in diabetes and metabolic disorders. Its potential applications extend to studies on glycemic control and the development of therapeutic agents targeting carbohydrate metabolism. -
α-Glucoside Hydrolase Inhibitor
Adiposin is an α-glucoside hydrolase inhibitor derived from microbial metabolism. This compound exhibits significant biological activity by modulating carbohydrate metabolism, making it a valuable tool in the study of metabolic pathways. It has potential applications in obesity research and the investigation of glycemic control mechanisms. -
Psychoactive Alkaloid
(-)-Mesembrine is a psychoactive alkaloid primarily derived from Sutherlandia frutescens. This compound acts as a partial agonist at the serotonin receptor, contributing to its psychoactive effects. It has been investigated for its potential applications in mood enhancement and cognitive function research. Additionally, (-)-Mesembrine may offer insights into therapeutic strategies for mood disorders. -
Alkaloid
Thalicminine is an alkaloid derived from Thalictrum species, known for its respiratory stimulant properties. This compound exhibits a transient hypotensive effect in canine models and has been shown to extend the hypnotic effects of chloral hydrate in murine studies. Thalicminine serves as a valuable tool in pharmacological research, particularly in studies investigating respiratory and sedative mechanisms. -
Flavonoid
Calycopterin is a flavonoid compound sourced from the leaves of Digitalis thapsi, primarily known for its immunosuppressive properties. This compound has demonstrated potential in modulating immune responses, making it suitable for research applications related to immune diseases and therapeutic interventions. Its distinctive biological activity positions calycopterin as a valuable reagent for exploring the underlying mechanisms of immune regulation. -
Natural Product
2-Heptyl-4,6-dihydroxybenzoic acid is a naturally occurring compound derived from orcinol. This chemical is of interest in various biological studies due to its potential antioxidant properties and involvement in metabolic pathways. It serves as a valuable reagent for research applications focusing on natural products and their effects on biological systems. -
Sesquiterpenoid Compound
Siegesbeckiol is a sesquiterpenoid compound derived from Isodon flavidus. This natural product exhibits significant biological activity, primarily as an anti-inflammatory agent. It is commonly used in research focused on exploring its therapeutic potential and mechanisms of action in various biological systems. -
Natural Product
2-Nonyl alcohol is a natural product that acts as a metabolite derived from the fermentation of the strain PJ16. This compound exhibits potential biological activity relevant to various research applications, including studies on microbial metabolism and the exploration of biosynthetic pathways. As a versatile reagent, it can be utilized in the investigation of biotransformation processes and the development of green chemistry protocols. -
Natural Products
Dihydrosamidin is a coumarin derivative derived from the fruits of Ammi visnaga. This compound promotes neuroplasticity and modulates metabolic processes, including glycolysis and oxidative phosphorylation, while enhancing antioxidant defenses. Additionally, Dihydrosamidin has been shown to inhibit triacylglycerol accumulation in 3T3-L1 preadipocytes. Its biological activities make it valuable for research applications in neuroprotection and anti-obesity studies. -
Natural Product
Jaconine hydrochloride is a natural product isolated from the honey of Ragwort (Senecio jacobaea). This compound exhibits potential biological activity and is utilized in various research applications, particularly in studies examining the effects of natural products on biochemical pathways and their therapeutic potential. Its unique properties make it a valuable reagent for investigations into the pharmacological effects of plant-derived substances.
