Natural Products

Items 1401-1450 of 3710

Page
per page
Set Descending Direction
Catalog No.
Product Name
Application
Product Information
Citations
  1. Natural Product

    (-)-Camphor is a natural product derived from the tree Cinnamomum camphora, known for its role as a terpene. This compound exhibits various biological activities, including anti-inflammatory and analgesic effects, making it suitable for research in pharmacology and natural product studies. Its applications extend to the exploration of traditional medicine and the development of therapeutic agents.
  2. Natural Product

    15-Methoxypinusolidic acid is a labdane diterpene compound derived from the leaves of Calocedrus microlepic. This natural product exhibits significant biological activity, particularly in the modulation of cellular pathways. It is primarily utilized in research applications investigating its potential therapeutic effects and mechanisms of action in various biological systems.
  3. Natural Product

    Texasin is a natural product derived from Baptisia australis, known for its potential biological activity. This compound has been studied for its effects in various biochemical research applications, including its role in modulating cellular processes and examining its effects on signaling pathways. Researchers may utilize Texasin to explore its therapeutic potentials and investigate mechanisms of action in relevant biological contexts.
  4. Antioxidant Flavonoid

    Patulitrin is an antioxidant flavonoid that exhibits significant scavenging activity against DPPH radicals and inhibits soybean lipoxygenase, making it a valuable compound for oxidative stress research. Additionally, Patulitrin demonstrates antihypertensive properties, highlighting its potential therapeutic applications in cardiovascular health. This compound can be isolated from Anthemis tinctoria, furthering its relevance in phytochemical studies.
  5. Diterpenoid

    6,7-Dehydroferruginol is a diterpenoid compound derived from the dichloromethane extract of Juniperus communis wood. This compound exhibits a specific profile in biological assays, as it does not inhibit 12(S)-lipoxygenase (12(S)-LOX) activity or the production of 12(S)-HETE at a concentration of 100 μg/mL. Its unique biochemical characteristics make it a valuable tool for research in lipid signaling pathways and enzyme activity modulation.
  6. Natural Product

    Ethyl 2,4,6-trihydroxybenzoate is a natural product derived from Pueraria lobata, exhibiting notable triterpenoid properties. It serves as a valuable reagent for research investigating the biological activities and potential therapeutic applications of plant-derived compounds. This compound is utilized in studies focused on antioxidant and anti-inflammatory mechanisms, contributing to a deeper understanding of natural product chemistry.
  7. Bioactive Secoiridoid Derivative

    Ligustroside, a bioactive secoiridoid derivative, primarily targets mitochondrial bioenergetics, demonstrating significant potential in models of early Alzheimer's disease and brain aging. Its mechanisms of action appear not to interfere with amyloid-beta production, making it a valuable compound for neurodegenerative research. Additionally, Ligustroside effectively inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages, highlighting its role in inflammatory responses.
  8. Flavonoid Compound

    3,5,7-Trimethoxyflavone is a flavonoid compound that exhibits inhibitory action on TNF-α-induced expression and secretion of MMP-1 in cells. This compound is beneficial for research focusing on skin damage amelioration and has potential applications in dermatological studies aimed at understanding inflammation and extracellular matrix remodeling.
  9. Nature Product

    3,3′-Bisdemethylpinoresinol is a naturally occurring lignan known for its ability to inhibit matrix metalloproteinase-1 (MMP-1) in UVA-irradiated human dermal fibroblasts. This compound is primarily isolated from the seeds of Morinda citrifolia and is of interest in research focused on skin aging and photodamage. Its biological activity may provide insights into therapeutic strategies for maintaining skin integrity in response to ultraviolet radiation.
  10. Napthoquinone

    (Rac)-Arnebin 1 is a naphthoquinone compound derived from Arnebia nobilis, consisting of the racemic mixture of β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin. This compound exhibits notable anti-tumor activity, making it a valuable tool for cancer research. Its applications include investigating the mechanisms of action for therapeutic agents and exploring potential benefits in oncology studies.
  11. Flavonoid Compound

    Averionol is a flavonoid compound that serves as a potential lead in the development of anti-HIV agents. Although it lacks significant inhibitory activity against HIV integrase, its structural properties may provide insights for further modifications and optimization in antiviral research. This compound is relevant for studying flavonoid effects in therapeutic contexts, particularly in the quest to enhance HIV treatment strategies.
  12. HMGCR Inhibitor

    Ganoderenic acid K is a potent inhibitor of HMG-CoA reductase (HMGCR), demonstrating an IC50 value of 16.5 μM. This natural compound can be extracted from the fruiting bodies of Ganoderma lucidum. Ganoderenic acid K has significant implications in cholesterol regulation research and potential therapeutic applications in hyperlipidemia and cardiovascular diseases.
  13. Natural Product

    Lepidiline A is a natural product with a specific inhibitory effect on HSD17B1 activity. It demonstrates notable cytotoxicity against HL-60 cells, with an IC50 value of 32.3 μM. Additionally, Lepidiline A enhances the bioconversion efficiency of sex hormones, facilitating the conversion of estrogen into 17β-estradiol and 4-androsten-3,7-dione into testosterone. This compound is of interest for research related to reproductive biology and hormonal modulation.
  14. Alkaloid

    Coccinine is an alkaloid with a primary mechanism as a weak inhibitor of the serotonin transporter (SERT) and P-glycoprotein (P-gp), exhibiting IC50 values of 196.3 μM and 0.96 mM, respectively. This compound displays notable anti-tumor activity across various cancer cell lines, including MCF7, Hs578T, MDA-MB-231 (breast cancer), HCT-15 (colon cancer), and A549 (lung cancer). Coccinine serves as a valuable tool in the research of tumor biology and neurological disorders.
  15. Alkaloid

    (E/Z)-Piperine is an alkaloid known for its pungent characteristics. This compound exhibits a range of biological activities, including anti-inflammatory, immunomodulatory, and anti-cancer effects, along with antispasmodic and anti-secretory properties. Notably, (E/Z)-Piperine demonstrates significant neuroprotective effects in models of Alzheimer's disease and Parkinson’s disease, making it a valuable tool for research in neurodegenerative disorders.
  16. Natural Product

    Wallichinine is a natural product derived from the twigs and leaves of Trigonostemon thyrsoideum, classified as a diterpenoid. It exhibits notable biological activities that may be useful in various research applications, particularly in studies focused on natural compounds and their pharmacological properties. Researchers may explore its potential effects on cellular processes and its applications in drug discovery.
  17. Natural Compound

    Pepluanin A is a natural compound derived from Euphorbia peplus L., exhibiting potent inhibitory activity against P-glycoprotein (Pgp). This jatrophane diterpene demonstrates more than double the effectiveness of Cyclosporin A in inhibiting Pgp-mediated transport of Daunomycin. Its significant biological activity positions Pepluanin A as a valuable reagent for research involving drug resistance and pharmacokinetics.
  18. Phenolic Substance

    Salviaplebeiaside is a phenolic compound isolated from the aerial parts of Vitex negundo var. cannabifolia. It functions as an inhibitor of class I P-glycoprotein, which plays a critical role in drug transport and metabolism. This reagent is valuable for research applications focused on drug resistance mechanisms and pharmacokinetics.
  19. Natural Compound

    Jatrophane 5 is a natural compound derived from Jatropha carcas L., targeting P-glycoprotein (P-gp). It exhibits potent inhibitory activity against P-gp, surpassing that of R(+)-verapamil and Tariquidar in colorectal multi-drug resistant DLD1-TxR cells. This compound is valuable for research into overcoming multidrug resistance in cancer treatment and enhancing drug efficacy in resistant cell types.
  20. Diterpenoid alkaloid

    Lappaconine is a diterpenoid alkaloid known for its potential role in biochemical research. It facilitates the α-hydroxylation of β-oxo esters, making it a valuable reagent for synthetic organic chemistry applications. Its unique chemical properties may also contribute to studies investigating biological pathways and therapeutic targets related to alkaloids.
  21. Natural Product

    β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA) that plays a critical role in plant stress responses. This compound accumulates in the vacuole and the endoplasmic reticulum, allowing for the rapid release of free ABA under abiotic stress conditions such as dehydration and salinity. β-D-Glucopyranosyl abscisate is integral to maintaining ABA homeostasis, making it a valuable tool for research on plant physiology and stress signaling pathways.
  22. Aconitum Alkaloid

    6-Benzoylheteratisine acts as an antagonist of tetrodotoxin and targets sodium channels, demonstrating potential neuroprotective activity. It effectively inhibits the influx of sodium ([Na+]i) and calcium ([Ca2+]i) ions, as well as the release of glutamate, making it relevant for the study of excitatory neurotransmission. Additionally, 6-Benzoylheteratisine has shown inhibitory effects on neuronal activity associated with epileptiform burst discharge, suggesting its utility in neurological research and potential therapeutic applications in epilepsy.
  23. Alkaloid

    Picraline is a natural alkaloid that acts primarily on opioid receptors, exhibiting binding affinities with Ki values of 132 μM for μ-opioid receptors (μOR), 2.38 μM for κ-opioid receptors (κOR), and 98.8 μM for δ-opioid receptors (δOR). It is of significant interest in research focused on opioid signaling pathways, analgesic effects, and potential therapeutic applications in pain management. This compound is valuable for studies exploring the modulation of opioid receptor activity and the related biological responses.
  24. Natural Product

    6-Hydroxyflavanone is a natural product isolated from the leaves of Muntingia calabura that targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A receptors. This compound exhibits anti-inflammatory properties and demonstrates potential in alleviating neuropathic pain. Additionally, 6-Hydroxyflavanone is a valuable tool for research into diabetes and related metabolic disorders.
  25. Naphthoquinone Derivative

    Naftazone is a naphthoquinone derivative that primarily targets vascular health. It exhibits protective effects on blood vessels, enhances venous tonicity and capillary resistance, and promotes improved lymphatic and venous circulation. This compound is valuable for research applications focusing on venous insufficiency and related vascular disorders.
  26. Natural Compound

    Ditryptophenaline is a natural compound derived from the metabolites of Aspergillus flavus. It functions as an antagonist of the substance P receptor, demonstrating significant anti-inflammatory activity. This compound is valuable for research focusing on neurogenic inflammation and pain modulation. Its biological properties make it a relevant tool for exploring therapeutic pathways in inflammatory diseases.
  27. Antispasmodic Opioid Alkaloid

    Pargeverine hydrochloride is an antispasmodic opioid alkaloid that primarily targets muscarinic cholinergic receptors, exhibiting a moderate and non-selective blockade. This compound is utilized in research to investigate mechanisms underlying painful spasms and their management. Its application in understanding muscle contraction and relaxation makes it a valuable reagent in pharmacological studies.
  28. Alkaloid

    Frititorine A is a steroidal alkaloid derived from the bulbs of Fritillaria tortifolia. It functions primarily by relaxing acetylcholine-induced tracheal contractions, demonstrating potential as a therapeutic agent in respiratory conditions. This compound is valuable for researchers investigating mechanisms of airway relaxation and potential treatments for asthma-related disorders.
  29. Bisbenzylisoquinoline Alkaloid Secoderivative

    S-Secoantioquine is a bisbenzylisoquinoline alkaloid secoderivative that primarily targets dopamine receptors. It exhibits weak displacement activity on the 3H-SCH 23390 binding site and demonstrates certain displacement activity on the 3H-raclopride binding site in rat striate membrane experiments. This compound is useful for research in neuropharmacology and may aid in understanding the mechanisms of dopaminergic signaling.
  30. Natural Alkaloid

    Pyrrole-2-carboxylic acid is a natural alkaloid derived from the marine bacterium Pelomonas puraquae sp. Nov. This compound acts as a precursor in the biosynthesis of various biologically active pyrrole derivatives, including clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin. Its unique structure and biological origins make it a valuable reagent for research in natural product chemistry and synthetic biology applications.
  31. Long-chain Aldehyde Component

    Octadecanal is a long-chain aldehyde characterized by its hydrophobic nature. It is present in the phospholipid fractions of thigh and breast muscles in broiler chickens, playing a significant role in lipid metabolism and cellular signaling. This compound is utilized in biochemical research investigating lipid-related pathways, fatty acid metabolism, and its implications in poultry science.
  32. Natural Biogenic Amine

    4-Hydroxybenzylamine is a natural biogenic amine involved in plant metabolism. It is formed through the catabolism of glucosinolates, utilizing glutamine as a non-classical ammonia donor. This compound is employed in research focused on plant amine biosynthesis and offers insights into the physiological roles of amines in various biological processes.
  33. Linear Oligosaccharide

    Maltohexaose is a linear oligosaccharide composed of six glucose units. It is derived from amylose, amylopectin, and whole starch and exhibits significant biological activity by inhibiting the proliferation of P-815 cells. This compound is useful in various research applications, particularly in studies related to cell growth modulation and carbohydrate metabolism.
  34. Cyclic Oligosaccharide

    γ-Cyclodextrin is a cyclic oligosaccharide composed of eight glucose units, primarily acting as a molecular scaffold for enhancing solubility. Its ability to form water-soluble inclusion complexes with hydrophobic compounds significantly improves the bioavailability of poorly soluble drugs. γ-Cyclodextrin is utilized extensively in pharmaceutical formulations and food applications to enhance flavor stability and efficacy. Additionally, it is recognized for its favorable safety profile in various research settings.
  35. Natural product

    Calcium Phytate, a natural phosphorus-containing compound, is primarily sourced from plant materials such as cereals and legumes. It has been demonstrated to exhibit chelation properties, which may aid in alleviating heavy metal toxicity, specifically lead poisoning. Research applications include studies on mineral absorption, gastrointestinal health, and the impact of dietary phytates on nutrient bioavailability.
  36. Monosaccharide

    β-D-Fructose is a monosaccharide that serves as a fundamental building block in carbohydrate chemistry. It has been shown to be a key precursor for the synthesis of derivatives that possess significant antiproliferative activity against breast cancer MCF-7 cells. This compound is essential for research applications focused on cancer metabolism and therapeutic development targeting glycosylation processes.
  37. Oligosaccharide

    D-Panose is an oligosaccharide comprised of glucose units connected by specific glycosidic bonds. This compound plays a significant role in carbohydrate metabolism and is instrumental in various biological processes. It is utilized in research applications focused on glycomics, food science, and the study of metabolic pathways, offering insights into oligosaccharide behavior and function.
  38. Fucoidan Oligosaccharide Substrate

    GDP-L-fucose disodium is a nucleotide sugar that serves as a crucial substrate for the biosynthesis of fucose oligosaccharides. It donates the fucose moiety essential for oligosaccharide formation, playing a significant role in various biological processes. This compound is primarily produced through the de novo pathway, with a secondary contribution from the remedial metabolic pathway. Its applications include studies in glycosylation and carbohydrate-protein interactions relevant to cell signaling and immune responses.
  39. Anthraquinone Dye

    Flavokermesic acid is an anthraquinone dye primarily found in extracts of the Diaspididae family of insects. It serves as a valuable tool for studying the biosynthetic pathways associated with insect-derived anthraquinone pigments, contributing to insights into pigment production and its biological significance. This compound is utilized in various research applications focused on natural product chemistry and insect biology.
  40. Chymopapain

    Chymopapain is a non-specific proteoglycanase extracted from the papaya plant, primarily targeting proteoglycans within the extracellular matrix. Its enzymatic activity leads to the degradation of disc material, resulting in disc narrowing when applied directly to intervertebral discs. This property makes chymopapain valuable in research focusing on the treatment of herniated lumbar discs, contributing to the understanding of intervertebral disc health and potential therapeutic interventions.
  41. Natural Ceramide

    C12-Ceramide (N-Lauroyl-D-erythro-sphingosine) is a naturally occurring ceramide that plays a critical role in cellular signaling and membrane dynamics. This compound has been shown to enhance the cytotoxic effects of Doxorubicin in MDA-MB-231 cells, making it valuable for cancer research. Additionally, C12-Ceramide serves as an important diagnostic marker for types A and B Niemann-Pick disease, facilitating studies into sphingolipid metabolism and related pathologies.
  42. Metabolomic Signature Of Hyperlipidemia

    Sphingomyelin (d18:1/12:0) is a metabolomic biomarker associated with hyperlipidemia. This compound displays significant potential for diagnosing dyslipidemia and may aid in the early detection and prevention of adverse cardiovascular events. Its role in lipid metabolism research makes it a valuable tool for studies focusing on cardiovascular health and related metabolic disorders.
  43. Glycerol Glycoside

    2-O-(α-D-Glucopyranosyl)glycerol is a glycerol glycoside with notable applications in biochemical research. This compound exhibits significant properties related to membrane stabilization and cell protection, particularly under stress conditions. It is primarily extracted from the marine blue-green alga Oscillatoria sp., and serves as a valuable tool in studies of osmoregulation and cellular responses to environmental changes. Researchers can utilize this reagent in various biological assays to investigate its functional roles and potential therapeutic applications.
  44. Quinone Derivative

    7PPD-Q is a quinone derivative with antioxidant properties derived from substituted p-phenylenediamine. This compound exhibits toxicity against the marine bacterium Vibrio fischeri, with an EC50 value of 14.9 mg/L. 7PPD-Q may be utilized in research focused on assessing the environmental impact of pollutants and the effects of oxidative stress in various biological systems.
  45. Natural Product

    3-Methyl-2-butenal, a natural product derived from hops, is characterized by its conjugated aldehyde structure. This compound exhibits key biological activity, including potential applications in flavoring and fragrance development due to its unique aroma. Additionally, 3-Methyl-2-butenal serves as a valuable reagent in organic synthesis and can be employed in various research applications focused on natural product chemistry.
  46. Natural Product

    3-Keto petromyzonol is a natural product that primarily targets the modulation of gonadotropin-releasing hormone (GnRH) synthesis and release. This compound plays a pivotal role in influencing the hypothalamic-pituitary-gonadal (HPG) axis in immature sea lamprey. Its unique properties make it valuable for research into reproductive biology and neuroendocrine signaling pathways.
  47. Hepatotoxic Pyrrolizidine Alkaloid

    Lasiocarpine hydrochloride is a hepatotoxic pyrrolizidine alkaloid known to induce fatal liver veno-occlusive disease in vivo. Its toxicity is mediated through metabolic conversion to harmful intermediates, such as dehydrolasiocarpine and N-oxide. This compound is primarily utilized in research exploring liver toxicity mechanisms and the biological effects of pyrrolizidine alkaloids.
  48. Polysaccharide

    D-Ribose 1,5-diphosphate is a pentose phosphate that serves as a key intermediate in the Calvin cycle of photosynthesis. It is vital for the synthesis of carbohydrates, influencing the production of energy-rich compounds. This reagent is commonly utilized in studies of metabolic pathways and enzymatic functions in photosynthetic organisms.
  49. Natural Product

    Ethyl 3-methyl-2-butenoate is a natural product known for its role as a volatile compound isolated from sea buckthorn. This compound is utilized in various biological studies due to its distinctive odor and potential applications in flavor and fragrance industries. It may also serve as a valuable reference standard in analytical chemistry for the assessment of natural product compositions.
  50. Natural Products

    Thevetin A is a cardiac glycoside derived from the plant Cascabela thevetioides. It exhibits potent biological activity by inhibiting Na+/K+ ATPase, leading to increased intracellular calcium levels and enhanced contractility of cardiac muscle. This compound is primarily utilized in cardiovascular research to study its effects on cardiac function and potential therapeutic applications in heart disease.

Items 1401-1450 of 3710

Page
per page
Set Descending Direction