Other inhibitors

SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor. SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway.

MT-4 blocks the TG2/FN complex at the interface between cancer cells and the tumor niche. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.

ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes. ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 ??C.

NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity.

DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity.

Esonarimod is an antirheumatic drug, suppressing lymphocyte activating factor activity or biosynthesis.

GR148672X is a TGH inhibitor.

HAMNO, also known as NSC-111847, is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response.

ELN484228 is a cell-permeable alpha-Synuclein Blocker.

CPHPC is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. Serum amyloid P (SAP) is pentraxin with roles in inflammation and immune response.

Succimer is an orally active heavy metal chelator.

Pirinixil is a hypolipidemic agent of low toxicity.

Diflumidone is a non-steroidal antiinflammatory drug.

Anitrazafen is a topically effective antiinflammatory agent.

AMZ30 is a selective, covalent inhibitors of protein phosphatase methylesterase-1(PME-1) with IC50 value of 600 nM.

GJ-103 is an active analog of the read-through compound GJ072. CAS: 1459687-96-7 (Sodium salt) 1459687-89-8 (Free Acid)

EG01377 TFA salt is a selective neuropilin-1 (NRP1) antagonist. CAS: 2227996-00-9 (Free base)

MLS0315771 is a potent competitive phosphomannose isomerase (MPI) inhibitor.

Sulfabromomethazine, also known as Bromosulfamethazine, NSC 5874, SN 3517, is a long-acting derivative of sulfamezathine that is used in the poultry, swine and cattle industries for the treatment of coccidiosis.

KC01 is a covalent inhibitor of ABHD16A.

Chlorthalidone is a diuretic drug used to treat hypertension. It is described as a thiazide diuretic. Compared with other medications of the thiazide class, chlortalidone has the longest duration of action but a similar diuretic effect at maximal therapeutic doses. Chlortalidone is often used in the management of hypertension and edema. Chlorthalidone directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in sodium, chloride, bicarbonate, and potassium secretion resulting in the excretion of water.

Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group group attached to OH. It is a colourless liquid that is slightly soluble in water, but miscible with most organic solvents.

Carbasalate Calcium, also known as Alcacyl and Omegin, is a non-steroidal anti-inflammatory drug used to treat pain and fever.

Metaxalone is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. It is considered to be a moderately strong muscle relaxant, with relatively low incidence of side effects. Metaxalone appears to interact with the cytochrome p450 system and may act as a general central nervous system depressant.

Oxaceprol is an antirheumatic Agent.

Anisindione (brand name Miradon) is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K?Cmediated gamma-carboxylation of precursor proteins.

Suxibuzone is a analgesic used for joint and muscular pain. It is a prodrug of the non-steroidal anti-inflammatory drug phenylbutazone, and is commonly used in horses.

Bendroflumethiazide is a thiazide diuretic used to treat hypertension. Bendroflumethiazide works by inhibiting sodium reabsorption at the beginning of the distal convoluted tubule and may play an important role in the treatment of mild heart failure.

Laquinimod (ABR-215062) is a potent immunomodulator.