Catalog No.
Product Name
Application
Product Information
Citations
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Drug Intermediate
5-Br-4-Cl-Pyrrolo-pyroxypyridine serves as a synthetic intermediate for molecular glues. It is particularly relevant in the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation. This compound is essential for research applications focused on proteostasis and the modulation of protein interactions. -
Drug Intermediate
4-Hydroxy-3,3-dimethylcyclohexanone serves as a crucial intermediate in the synthesis of human acetylcholinesterase (hAChE) inhibitors. Its role in the development of hAChE inhibitors makes it significant for research in neuropharmacology and disease models related to cholinergic dysfunction. This compound's unique structural properties facilitate the exploration of therapeutic agents targeting cognitive disorders. -
Drug Impurity
Dexamethasone impurity 2 is a chemical impurity associated with Dexamethasone. It serves as an important reference standard for purity analysis and quality control in pharmaceutical research. This compound aids in the assessment and characterization of Dexamethasone formulations, facilitating compliance with regulatory standards. -
Degradation Impurity in Docetaxel
7-epi-10-Oxo-10-deacetyl baccatin III is a degradation impurity found in Docetaxel. This compound is important for research involving the stability and degradation pathways of taxane-based chemotherapeutics. It serves as a vital reference standard for evaluating the purity and efficacy of Docetaxel formulations, thus aiding in the development of stable therapeutic agents. -
Drug Intermediate
H-Aeg(Fmoc)-OBzl hydrochloride is an Fmoc-protected aminoethylglycine derivative with a benzyl ester moiety. It serves as a versatile drug intermediate, facilitating the synthesis of peptide nucleic acids and protected oligomers. This compound is valuable in various research applications, including peptide synthesis and molecular biology studies. -
Drug Intermediate
LY280748 is a potent imidazolate receptor ligand, functioning primarily as a drug intermediate. This compound exhibits significant biological activity, making it a valuable tool in pharmacological research and development. Its application spans various studies focused on receptor-mediated signaling pathways and the synthesis of novel therapeutic agents. -
Drug Impurity
Cyclosporin impurity 2, also known as Acetoxy cyclosporin A acetate, is a known impurity of cyclosporin. This compound may arise during the synthesis or formulation of cyclosporin and can be important for analytical and quality control purposes in pharmaceutical research. It serves as a reference standard for the evaluation of cyclosporin purity and plays a critical role in the assessment of drug safety and efficacy. -
Drug Intermediate
GA44 is a C20-gibberellin that serves as an intermediate in the early 13-hydroxylation pathway of gibberellin biosynthesis. This compound plays a critical role in the synthesis of biologically active gibberellins, which are important regulators of plant growth and development. GA44 is utilized in research applications focusing on plant hormone signaling and metabolism studies. -
Drug Intermediate
H-Aeg(Fmoc)-OH hydrochloride is an Fmoc-protected aminoethylglycine monomer that features a free carboxyl group. This reagent serves as a versatile building block for peptide nucleic acid synthesis, facilitating the construction of PNA oligomers. Its chemical structure supports the incorporation of aminoethylglycine into various bioconjugates, making it valuable in nucleic acid research and related fields. -
Drug Intermediate
N,N'-bis-Cbz-β-Alethine is an active ester that serves as a crucial intermediate in the synthesis of β-alethine. β-Alethine has been shown to induce cell differentiation and exhibits potential anti-tumor properties. The conversion of N,N'-bis-Cbz-β-Alethine to β-alethine is achieved through the removal of the carbobenzoxy (CBZ) groups using hydrogen bromide in glacial acetic acid. This compound is valuable for research focused on cell differentiation mechanisms and anti-cancer drug development. -
Drug Intermediate
Azidoethyl-oxime-Glucose-GalNAc serves as a versatile drug intermediate, primarily aimed at synthesizing disaccharide linkers. This compound plays a crucial role in the development of glycan site-directed antibody-drug conjugates (ADCs), facilitating targeted delivery in therapeutic applications. Its unique chemical structure allows for efficient modification and incorporation into complex carbohydrates, making it essential for advancing glycoscience research and drug development. -
Drug Intermediate
K-13 is a cyclic peptide compound that serves as a valuable drug intermediate through its role in organic synthesis. Its production involves a highly efficient synthetic route utilizing intermolecular and intramolecular Negishi cross-coupling reactions. This streamlined synthesis approach makes K-13 a significant reagent for research applications in drug development and peptide chemistry. -
Drug Intermediate
Methoxycarbonyl isocyanate serves as a versatile drug intermediate primarily utilized in organic synthesis. Its reactive isocyanate group allows for the formation of various carbamates and ureas, making it valuable in the development of pharmaceutical compounds. This reagent is essential for studying and optimizing synthetic pathways in drug discovery and development. -
Drug Intermediate
Guaietolin is an organic synthesis intermediate primarily used in the development of sulfonamide esters that exhibit carbonic anhydrase inhibitory activity. It serves as a significant marker of hypertension, as its levels are notably reduced in plasma metabolites of affected individuals. Guaietolin is applicable in research focused on glaucoma and hypertension, providing a valuable tool for investigating these cardiovascular and ocular conditions. -
Drug Impurity
(2,3-Dimethoxyphenyl)methanol is identified as a drug impurity often encountered during the synthesis of various pharmaceutical compounds. Its structural features may influence the physicochemical properties of the primary drug substance. This compound is relevant for analytical studies focused on purity assessment and stability testing within pharmaceutical research and development. -
Drug Intermediate
Bimatoprost isopropyl ester acts as a drug intermediate with a specific focus on the prostaglandin F2α analogs. It is characterized by a double bond at the 13-14 position and an inverted hydroxyl group at C-15. Notably, this compound has demonstrated significant biological activity, exhibiting an IC50 of 30 nM in FP receptor binding assays, indicating its potential role as an impurity in latanoprost formulations. Additionally, in vivo studies revealed that a dose of 3 μg can lead to a 1.9 mmHg decrease in intraocular pressure in normotensive cynomolgus monkeys, making it a valuable reagent for research involving ocular therapies. -
Drug Intermediate
Fmoc-Aeg-OtBu is a versatile intermediate used in solid-phase peptide synthesis. It acts as a building block for the introduction of pseudoproline motifs and backbone modifications, enhancing the stability and folding properties of peptides. This compound is essential for researchers developing peptide therapeutics and studying protein structure and function. -
Drug Intermediate
1-epi-Regadenoson ethyl ester is a key intermediate in the synthesis of the α-isomer impurity of Regadenoson, a highly selective agonist for the adenosine A2A receptor. This compound is essential for research involving adenosine receptor biology and contributes to the understanding of cardiovascular function and cellular signaling pathways. Its application extends to the development and analysis of therapeutic agents targeting adenosine receptors. -
Drug Impurity
Ranolazine impurity 10 is a chemical impurity associated with the cardiovascular drug Ranolazine, which primarily targets sodium channels. This impurity is significant for analytical and quality control purposes in pharmaceutical research and development, aiding in the assessment of the drug's purity and safety profile. Its identification and quantification are critical for compliance with regulatory standards in the drug manufacturing process. -
Drug Intermediate
LBA-NHS is a derivative of lactobionic acid (LBA) designed as a drug intermediate. It functions by enabling the modification of lipids and acts as a coating for biological materials, enhancing the efficient and specific binding of LBA to carrier molecules. This compound is valuable in research applications involving drug delivery systems and biomaterials engineering. -
Drug Intermediate
5β-Dihydrocortisone acetate serves as a crucial intermediate in the synthesis of tetrahydrocortisone 3-glucuronide. This compound plays a significant role in biochemical research and pharmaceutical development, particularly in the study of corticosteroid metabolism and glucuronidation processes. Its use can facilitate investigations into the pharmacokinetics of glucocorticoids and their conjugates, contributing to a better understanding of steroid biochemistry. -
Drug Intermediate
1-Amino-3-(phosphonooxy)-2-propanone acts as a crucial drug intermediate in the synthesis of vitamin B6. This compound facilitates biochemical reactions essential for the production of vitamin B6 derivatives, contributing to studies in nutrition and metabolism. Its application in synthetic pathways enhances research related to vitamin synthesis and potential therapeutic developments. -
Drug Impurity
Fingolimod impurity 3 is identified as a chemical impurity associated with Fingolimod, a sphingosine 1-phosphate receptor modulator. This compound serves as an important reference for assessing the purity and quality of Fingolimod formulations in pharmaceutical research. Its presence may influence the pharmacological profile and efficacy of the parent drug, making it a valuable component in analytical studies and quality control processes. -
Drug Intermediate
AldoView precursor-1 is a crucial intermediate in the synthesis of the radioactive PET tracer [18F] AldoView. This compound serves as a selective tracer for imaging aldosterone synthase activity, making it valuable in the study of primary hyperaldosteronism. Its application facilitates non-invasive imaging and further research into aldosterone-related disorders. -
Drug Intermediate
Citreomontanin, an α-Pyrone polyketide, serves as a key drug intermediate in the synthesis of Citreoviripyrone A. Isolated from the mycelium of endophytic Penicillium species in Catharanthus roseus, Citreomontanin plays a critical role in facilitating research on compounds with biological activity. Notably, Citreoviripyrone A exhibits moderate inhibitory effects on the proliferation of HCT116 colorectal cancer cells, highlighting its potential utility in cancer research and drug development. -
Drug Intermediate
Fmoc-Aeg-OMe hydrochloride is a methyl ester derivative of Fmoc-protected aminoethylglycine, primarily used as a drug intermediate in chemical synthesis. This compound plays a crucial role in the synthesis of polyamide nucleic acids, facilitating research in nucleic acid chemistry and related fields. Its unique structure and properties make it valuable for developing novel therapeutic agents and exploring biomolecular interactions. -
Drug Intermediate
Valone is a critical intermediate in the synthesis of diorganotin(IV) complexes. Its unique chemical properties facilitate the creation of organotin compounds, which are essential in various applications, including agricultural and pharmaceutical research. This reagent serves as a fundamental building block for the development of advanced materials and bioactive substances in chemical research. -
Drug Intermediate
5-Bromo-1,2-difluoro-3-methoxybenzene serves as a crucial drug intermediate in synthetic chemistry. It functions as a precursor for the development of glucocorticoid receptor (GR) ligands, enabling the exploration of GR-targeted therapies. This compound is applicable in pharmaceutical research for the synthesis of novel therapeutic agents. -
Drug Intermediate
Geranylamine is an acyclic monoterpene amine that functions as a drug intermediate in the synthesis of various TRP channel modulators and antibacterial agents. Its structural properties make it a valuable precursor in medicinal chemistry, facilitating the development of compounds aimed at modulating ion channel activity and addressing bacterial resistance. This compound plays a crucial role in advancing research in pharmacology and therapeutic applications. -
Drug Intermediate
DFO-BCN is a chemical intermediate utilized in the synthesis of the PET/CT imaging agent DFO-CPC634 via click chemistry. This compound serves as a valuable tool in radiopharmaceutical development, enabling effective labeling and visualization in molecular imaging studies. Its role as a precursor enhances the efficiency of tracer synthesis, supporting research in diagnostic imaging applications. -
Drug Intermediate
((4-(tert-Butyl)phenyl)sulfonyl)methionine serves as a versatile drug intermediate in chemical synthesis. This compound is primarily utilized for the construction of peptides, facilitating the creation of diverse biological molecules. Its sulfonyl group enhances the stability and efficacy of peptide linkages, making it a valuable reagent in medicinal chemistry and drug development research. -
Drug Impurity
Rivaroxaban impurity 69 is a chemical impurity associated with the anticoagulant drug Rivaroxaban. It is commonly utilized in analytical research to assess the purity and quality of Rivaroxaban formulations. Understanding the presence of this impurity is critical for ensuring the safety and efficacy of therapeutic applications involving Rivaroxaban. -
Drug Intermediate
2,4,6-Tribromo-3-methylphenol is a brominated phenolic compound widely utilized as a drug intermediate. It exhibits significant biological activity, serving as a precursor in the synthesis of various pharmaceuticals. Researchers employ this compound in studies related to organic synthesis and medicinal chemistry, facilitating the development of novel therapeutic agents. -
Drug Intermediate
(S)-Oxybutynin is a key pharmaceutical intermediate primarily involved in the synthesis of antifungal agents. This compound serves as an important building block in drug development, facilitating the creation of therapeutically relevant molecules. Its role in the synthesis pathway underscores its significance in both medicinal chemistry and pharmaceutical applications. -
Drug Intermediate
Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate primarily employed in the development of molecular glues. This compound serves as a crucial building block for the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation research and applications in drug discovery. Its structural properties make it valuable in the design of innovative therapeutic agents. -
Drug Intermediate
Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a key intermediate for drug synthesis, primarily targeting biphenyl-based derivatives. This compound serves as a versatile building block in the development of various pharmaceuticals, facilitating the preparation of more complex molecules in medicinal chemistry. Its structural features make it valuable for applications in drug discovery and development. -
Drug Intermediate
4-Methyl-5-nitropyridin-2-amine is a key drug intermediate utilized in the synthesis of pyrazolo-pyridine compounds with notable cytotoxic activity. This compound plays a significant role in pharmaceutical research and development, enabling the exploration of novel therapeutic agents. Its reactivity and structural properties make it a valuable tool for researchers focusing on targeted cancer therapies and related biological studies. -
Drug Intermediate
SCP-1 (Compound C-1) serves as a crucial intermediate in the synthesis of the non-opioid analgesic drug SRP-3D (DA). This compound is primarily utilized in research focused on neurological disorders, particularly pain-related conditions. Its role in drug development highlights its importance for advancing therapeutic strategies in pain management and related pathologies. -
Drug Intermediate
Cbz-Val-(triAc-β-D-glucoside methyl ester)-Cbz is a chemical intermediate primarily involved in the synthesis of antibody-drug conjugate (ADC) linkers. Its structural components facilitate the conjugation process, enhancing the efficacy of targeted drug delivery systems. This compound is essential in the development of sophisticated biopharmaceuticals aimed at improving therapeutic outcomes in cancer treatment. -
Drug Intermediate
2-Hydroxy-2-(2-methylpropyl)butanedioic acid serves as a key drug intermediate in the synthesis of diverse pharmaceutical compounds. Its unique structure facilitates the assembly of various active moieties, making it essential for drug development research. This reagent is valuable for chemists working on the design and synthesis of novel therapeutic agents. -
Drug Impurity
Vortioxetine impurity 9 is a synthetic byproduct of the cognitive enhancer Vortioxetine, primarily serving as a drug impurity reference standard. This compound is relevant in analytical chemistry for the assessment of Vortioxetine purity and stability. It is essential for quality control in pharmaceutical research and development, ensuring compliance with regulatory standards during drug formulation and testing. -
Drug Intermediate
5-Deoxy-D-ribose serves as a crucial building block in the synthesis of various anticancer compounds. This compound is employed as a drug intermediate, facilitating the development of therapeutic agents targeting cancer. Its structural properties enable researchers to explore diverse pathways in drug development and biochemical studies. -
Drug Intermediate
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate utilized in the development of molecular glue therapies. This compound plays a significant role in the synthesis of GSPT1 degrader-9, supporting research in targeted protein degradation. Its versatile applications make it an important reagent for studies focused on novel therapeutic strategies in cellular regulation and disease modulation. -
Drug Intermediate
Crotonamide is a chemical intermediate utilized in the synthesis of epidermal growth factor receptor (EGFR) inhibitors. Its application in drug development facilitates the creation of therapeutic agents targeting various forms of cancer characterized by aberrant EGFR signaling. Crotonamide serves as a vital precursor in the production of innovative pharmaceuticals designed to address critical oncological challenges. -
Drug Impurity
Febuxostat impurity 11 is a chemical impurity associated with Febuxostat, an inhibitor of xanthine oxidase. This impurity is crucial for the quality control and characterization of Febuxostat in pharmaceutical formulations. It is primarily used in the development and validation of analytical methods to ensure the purity and safety of drug products containing Febuxostat. -
Drug Intermediate
Doxorubicin-Boc (Dox-Boc) is a drug intermediate utilized in the synthesis of the Adamantane-Doxorubicin prodrug. This compound plays a crucial role in drug development by modifying the pharmacokinetic properties of doxorubicin, potentially enhancing its efficacy and reducing side effects. It serves as a valuable tool for researchers exploring innovative cancer treatment strategies. -
Drug Impurity
Cyclosporin impurity 1, also known as Isocyclosporin H, is a known impurity found in cyclosporin formulations. Its characterization is critical for ensuring the purity and efficacy of cyclosporin-based drugs. This compound may be utilized in quality control settings to monitor the presence of impurities in pharmaceutical products and help assess their impact on biological activity and safety. -
Ivermectin Impurity
Imidacloprid impurity 1 is an impurity associated with the synthesis of Ivermectin, a key antiparasitic agent. This compound may be utilized in research to assess the stability and purity of Ivermectin formulations, as well as in studies focused on the synthesis pathways of related compounds. Its role in the evaluation of pharmaceutical products makes it a valuable tool in chemical and pharmacological research. -
Drug Intermediate
Elcatonin, a synthetic analog of eel calcitonin, functions as a drug intermediate with significant implications in bone metabolism. It is known to increase bone mineral density and inhibit bone resorption, making it valuable in research related to osteoporosis and bone health. Additionally, Elcatonin exhibits central analgesic effects, thereby supporting applications in pain management studies. -
Drug Intermediate
(R,1R)-Tenofovir amibufenamide is a crucial drug intermediate utilized in the synthesis of tenofovir prodrugs. As a nucleoside reverse transcriptase inhibitor, tenofovir plays a significant role in the treatment of HIV and hepatitis B virus infections. This compound facilitates the purification process, thereby enhancing the development and application of antiviral therapeutics.
