Catalog No.
Product Name
Application
Product Information
Citations
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Vardenafil Impurity
Vardenafil N-oxide is an N-Oxide impurity of Vardenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor. This compound serves as an important analytical standard for quality control and characterization of Vardenafil formulations in pharmaceutical research. Its presence may impact the pharmacokinetics and efficacy of Vardenafil, making it relevant for studies on drug metabolism and safety assessments. -
Simvastatin Impurity
Anhydrosimvastatin is an impurity of Simvastatin, a known competitive inhibitor of HMG-CoA reductase, which plays a crucial role in cholesterol biosynthesis. This compound is primarily used in research to assess the purity and quality of Simvastatin preparations. Its characterization is essential for studies evaluating the pharmaceutical formulations and metabolic pathways influenced by cholesterol-lowering therapies. -
Trityl olmesartan medoxomil Impurity
Trityl olmesartan medoxomil impurity III is a characterized impurity of Trityl olmesartan medoxomil, which itself serves as an intermediate in the synthesis of Olmesartan medoxomil. This compound is utilized in chemical research to evaluate the purity of olmesartan formulations and assess related synthesis methods. Its presence as an impurity is crucial for understanding the intricacies of drug development and quality control processes within the pharmaceutical industry. -
Atorvastatin Impurity
Difluoro atorvastatin is an impurity of the HMG-CoA reductase inhibitor atorvastatin. This compound demonstrates significant activity by effectively reducing blood lipid levels. Additionally, difluoro atorvastatin is known to inhibit the proliferation and invasion of human smooth muscle cells, exhibiting IC50 values of 0.39 μM and 2.39 μM, respectively. It serves as a useful reference compound in the evaluation of atorvastatin purity and related studies in cholesterol management and cardiovascular research. -
Febuxostat Impurity
Febuxostat impurity 7 is a chemical impurity related to Febuxostat, a selective xanthine oxidase inhibitor with a Ki value of 0.6 nM. This impurity is important for quality control and characterization in drug development and analytical chemistry applications involving Febuxostat. Understanding its properties can aid in assessing the purity and stability of formulations containing Febuxostat. -
Daclatasvir Impurity
Daclatasvir Impurity C is a chemical impurity associated with Daclatasvir, a potent inhibitor of the Hepatitis C virus (HCV) NS5A protein. Its characterization is essential for assessing the purity and quality of Daclatasvir in pharmaceutical formulations. This reagent is valuable for researchers focusing on the pharmacological properties of antiviral compounds and for ensuring compliance in drug development processes. -
Hydroxychloroquine Impurity
Hydroxychloroquine Impurity F is a structural impurity associated with Hydroxychloroquine, a synthetic antimalarial agent. This compound demonstrates the ability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling pathways. Hydroxychloroquine has also been shown to effectively inhibit SARS-CoV-2 infection in vitro, making it a significant focus of research in virology and immunology. -
Prasugrel Impurity
Prasugrel chloride impurity is a chemical impurity associated with Prasugrel, extracted from patent US20130345428A1, line 0053. Prasugrel serves as a potent and orally active antagonist of the P2Y12 receptor, effectively inhibiting ADP-induced platelet aggregation. This reagent is useful for research applications related to platelet function and thrombotic disorders, aiding in the assessment of drug purity and compliance in pharmaceutical formulations. -
Impurity of Cetirizine 3-chloro
Cetirizine 3-chloro impurity is a structural variant of Cetirizine 3-chloro, primarily analyzed for its potential effects on pharmacological activity. As an impurity, it is relevant in various quality control and analytical chemistry applications when assessing the purity of Cetirizine formulations. The characterization of this impurity is essential for ensuring the safety and efficacy of related pharmaceutical products. -
Atorvastatin Impurity
3-Oxo Atorvastatin is an impurity of atorvastatin, which acts as an HMG-CoA reductase inhibitor. This compound is critical in studying the metabolic pathways associated with cholesterol synthesis and lipid regulation. Its role as an impurity is essential for accurately assessing the purity and efficacy of atorvastatin in pharmaceutical formulations and research applications. -
Remdesivir Impurity
Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of the antiviral agent Remdesivir, a nucleoside analogue primarily targeting viral RNA synthesis. This compound is relevant in assessing the purity and efficacy of Remdesivir, which has demonstrated potent antiviral activity against SARS-CoV and MERS-CoV, with EC50 values of 74 nM in human airway epithelial cells and 30 nM against murine hepatitis virus in delayed brain tumor cells. Research involving this impurity can aid in the development and validation of antiviral therapeutics, particularly in the context of COVID-19. -
Gefitinib Impurity
Gefitinib impurity 1 is a known impurity associated with the tyrosine kinase inhibitor gefitinib, which specifically targets the epidermal growth factor receptor (EGFR). This compound plays a role in research applications aimed at understanding gefitinib's mechanism of action and its effects on EGF-stimulated tumor cell proliferation. Gefitinib demonstrates a potent inhibitory effect on EGFR autophosphorylation and tumor cell growth, making it valuable for studies related to cancer therapeutics and the exploration of resistance mechanisms in oncological research. -
Macamide Impurity
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide is a known impurity of Macamide, primarily utilized in the study of lipid metabolism and signaling pathways. This compound can be valuable for researchers investigating the biological effects of macamide derivatives and their potential role in modulating cellular processes. Its distinct chemical structure allows for the exploration of its impacts on various biological systems. -
Drug Impurity
Clozapine impurity 3 is a known impurity associated with the antipsychotic agent Clozapine. It serves as a critical reference material for assessing the purity and quality of Clozapine formulations. This reagent is essential for research and analytical applications focused on drug development, impurity profiling, and safety assessments of pharmaceutical compounds. -
Cetilistat Impurity
Cetilistat impurity 1 is a known impurity of the anti-obesity agent Cetilistat, which inhibits pancreatic lipase. This compound demonstrates significant biological activity, inhibiting both rat and human pancreatic lipase with IC50 values of 54.8 nM and 5.95 nM, respectively. It is primarily utilized in research to assess the purity and efficacy of Cetilistat and related formulations in obesity-related studies. -
Daclatasvir Impurity
Daclatasvir Impurity B is an impurity of the antiviral agent Daclatasvir, which targets the HCV NS5A protein. This compound is significant for quality control and analytical purposes in the synthesis and formulation of Daclatasvir. It may also be utilized in research applications aimed at understanding the pharmacological properties and stability of Daclatasvir. -
Impurity of Pantoprazole
N3-Methyl pantoprazole is an impurity of the proton pump inhibitor Pantoprazole. It serves as a significant reference standard for quality control and analytical research in pharmaceutical development. Its characterization aids in understanding the metabolic pathways and stability of Pantoprazole, providing insight into the safety and efficacy profiles of related compounds. This reagent is essential for researchers examining the pharmacological aspects of proton pump inhibitors. -
Drug Intermediate
Memantine lactose adduct is a key intermediate in the synthesis of adamantane amine antibiotics. This compound is derived from the reaction of Memantine with lactose, facilitating the development of novel therapeutic agents. Its role in the production of antibiotic compounds makes it valuable for biological research and pharmaceutical applications. -
Zopiclone Impurity
Deschloro-Zopiclone is an impurity of Zopiclone, the first non-benzodiazepine compound that enhances the activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain. This compound is relevant for studies focused on the pharmacological profiles and safety assessments of Zopiclone. It can be utilized in research related to sleep disorders and the analysis of medication impurities. -
Drug Intermediate
SOS1 Ligand Intermediate-7 is a critical chemical intermediate utilized in the synthesis of the SOS1 ligand, an important modulator of cellular signaling pathways. This compound plays a significant role in the production of PROTAC SOS1 degrader-1, facilitating targeted protein degradation research. Its applications extend to studies involving SOS1 activation and its implications in various biological processes. -
Impurity
Pregabalin diacid is characterized as an impurity of Pregabalin, a lipophilic analog of GABA (γ-aminobutyric acid) with notable anxiolytic and anticonvulsant properties. Its primary mechanism involves interaction with the α(2)β subunit of voltage-gated calcium channels, which are prevalent in both the peripheral and central nervous systems. Pregabalin is known to effectively induce hypoalgesia and enhance the management of behavioral disorders, making this impurity relevant in the context of quality control and pharmacological research. -
Cytochrome P450 Inhibitor
Verapamil EP Impurity C hydrochloride is a known impurity of Verapamil, primarily acting as a Cytochrome P450 inhibitor. This compound exhibits significant biological activity as a calcium channel blocker, contributing to its role as a first-generation P-glycoprotein (P-gp) inhibitor. Its utility in research includes studies on drug metabolism, pharmacokinetics, and interactions with P-gp transporters, making it a valuable reagent for pharmacological investigations. -
Biochemical Reagent
Ap3A is a vasoactive molecule primarily known for its role in regulating intracellular calcium (Ca2+) levels. It has been shown to promote the proliferation of vascular smooth muscle cells, making it a valuable reagent for research into cardiovascular biology and vascular growth mechanisms. Its applications extend to studies focusing on cellular signaling pathways and vascular pathologies. -
Biochemical Assay Reagent
Cholesterol n-Octanoate is an ester formed through the reaction of cholesterol and caprylic acid, serving as a valuable biochemical assay reagent. This compound exhibits bioactive properties that may influence various physiological processes, including cholesterol metabolism and inflammation. Its applications extend to pharmaceutical research aimed at addressing conditions related to elevated cholesterol levels and inflammatory diseases, as well as potential use in the food industry to enhance texture and stability. -
Biochemical Reagent
18:1-12:0 Biotin PC is a biochemical reagent primarily used for lipid blot analysis to investigate the interactions between Niemann-Pick C2 (NPC2) protein and lipids. Additionally, it serves as a key component in the preparation of liposomes, facilitating studies on lipid transport and cellular uptake mechanisms. This compound supports various applications in lipid research and membrane biology. -
Biochemical Assay Reagent
1,2-Dioctanoyl-sn-glycero-3-phosphocholine is a phospholipid that serves as a vital component in liposome formulations and drug delivery systems. This compound facilitates the formation of stable bilayers and vesicles, enhancing drug encapsulation and targeted delivery. Its properties as a stabilizer and emulsifier contribute to improved solubility and bioavailability of therapeutic agents, making it an essential reagent for biochemical assays and pharmaceutical research. -
Biochemical Assay Reagent
DOPE-PEG(2000) Amine ammonium is an amphiphilic copolymer characterized by a polyethylene glycol (PEG) chain of 2000 Da covalently linked to a phospholipid. This molecular structure allows for the formation of lipid bilayers or micelles in aqueous environments, facilitating the development of liposomes or nanoparticles for targeted drug delivery applications. Additionally, the reactive alkyne groups enable the formation of triazole linkages, which are beneficial for bioconjugation and further functionalization in biochemical assays. -
Biochemical Assay Reagent
LNP Lipid-12 is a critical component for the formulation of lipid nanoparticles (LNPs). This reagent facilitates the encapsulation and delivery of nucleic acids, enhancing their stability and efficacy in cellular applications. LNP Lipid-12 is particularly valuable in gene therapy, mRNA delivery, and other biochemical assays that require efficient and targeted transport systems. -
Biochemical Assay Reagent
LNP Lipid-182 is a key biochemical assay reagent utilized in the formulation of lipid nanoparticles (LNPs). This compound facilitates efficient encapsulation and delivery of nucleotides and other therapeutic agents. Its application is particularly significant in the fields of gene therapy and vaccine development, where precise lipid assembly is critical for enhancing cellular uptake and bioavailability. -
Biochemical Assay Reagent
LNP Lipid II-10 is a biochemical assay reagent designed for the formulation of lipid nanoparticles (LNPs). This compound facilitates the production of LNPs, which are essential for drug delivery applications, particularly in mRNA therapeutics. Its role in enhancing lipid bilayer stability and encapsulation efficiency makes it a crucial tool for researchers in the fields of nanomedicine and vaccine development. -
Biochemical Assay Reagent
Atorvastatin calcium hydrate is a potent HMG-CoA reductase inhibitor, primarily utilized as a biochemical assay reagent. This compound effectively lowers levels of low-density lipoprotein (LDL) cholesterol and triglycerides, contributing to a decreased risk of cardiovascular events such as heart attacks and strokes. Its distinct chemical properties and mechanism of action make it valuable for research applications focused on lipid metabolism and cardiovascular health. -
Biochemical Assay Reagent
DOPG sodium is an anionic phospholipid that plays a critical role in biochemical assays by forming lipid bilayers in aqueous solutions. This compound is utilized in the generation of micelles, liposomes, and various artificial membranes, making it essential for membrane-related studies. Additionally, DOPG sodium demonstrates anti-inflammatory properties, supporting its use in research applications focused on inflammation and membrane dynamics. -
Biochemical Assay Reagent
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid primarily employed as a biochemical assay reagent. It features a positively charged ammonium head group paired with two hydrophobic tails, facilitating the formation of liposomes and lipid-based nanoparticles for efficient gene delivery. This compound is instrumental in gene therapy and vaccine development, enhancing cellular uptake of nucleic acids. Additionally, due to its surfactant properties, it finds applications in various formulations, although caution is advised due to potential toxicity and irritative effects. -
Biochemical Assay Reagent
DMPG sodium is a biochemical assay reagent functioning primarily as a liposome carrier. Its primary application involves encapsulating 6-shogaol, a compound known for its anticancer properties, enhancing its delivery and bioavailability. This enables more effective study of its therapeutic potential in cancer research. -
Biochemical Assay Reagent
Cholesterol 5α,6α-epoxide is an epoxide derivative of cholesterol that serves as an important biochemical assay reagent. It is formed through the enzymatic oxidation of cholesterol in the liver and other tissues and plays a crucial role as an intermediate in bile acid biosynthesis, which is essential for the digestion and absorption of dietary fats. Additionally, this compound may influence cholesterol metabolism and transport, though its precise biological functions are still under investigation. -
Biochemical Assay Reagent
1,2-Distearoyl-sn-glycero-3-phosphate sodium is a phospholipid utilized primarily in biochemical assays and as a critical component in liposome formulations and drug delivery systems. This compound enhances the encapsulation of therapeutic agents, facilitating targeted delivery and improving drug solubility and bioavailability. Its unique chemical properties contribute to its effectiveness as a stabilizer and emulsifier in diverse research applications. -
Biochemical Assay Reagent
Cholesterol-PEG 600 is a biochemical assay reagent with applications in life science research. This compound acts as a versatile biological material, facilitating studies involving lipid biochemistry and membrane dynamics. Its unique structure enhances solubility and stability, making it ideal for applications such as drug formulation and the examination of cholesterol-related processes in cellular environments. -
Biochemical Assay Reagent
Dihexadecyl hydrogen phosphate is a phospholipid compound utilized as a biochemical assay reagent. It exhibits emulsifying properties, facilitating the mixing of immiscible substances such as oil and water, thereby enhancing texture and stability in various formulations. This compound finds applications in both the food industry, particularly in processed food production, and the pharmaceutical sector, where it assists in the formation of micelles, liposomes, and artificial membranes for drug delivery and research experiments. -
Biochemical Assay Reagent
Cholesterol decanoate is an ester formed from the reaction of cholesterol and capric acid, serving as a biochemical assay reagent. It exhibits bioactive properties that may have implications in addressing medical conditions such as hypercholesterolemia and inflammation-related disorders. Furthermore, this compound has potential applications in the food industry to enhance texture and stability in various formulations. -
Biochemical Assay Reagent
Dehydroergosterol is a naturally occurring fluorescent sterol analog that serves as a biochemical assay reagent, exhibiting excitation and emission wavelengths of 325 nm and 375 nm, respectively. This compound mimics cholesterol in cellular membranes, allowing for real-time imaging when conjugated with cholesterol-binding proteins. It is an effective tool for studying the sterol environment and elucidating intracellular sterol transport dynamics in live cells. -
Biochemical Assay Reagents
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC (PLPC) is a phospholipid that serves as a key component in lipid bilayer model systems. It is utilized in biochemical assays to investigate membrane properties and dynamics, notably in studies involving lipid oxidation. When combined with oxidized lipids such as 1-palmitoyl-2-(13-hydroxy-9,11-octadecanedienoyl)-lecithin (OHPLPC) and 1-palmitoyl-2-(13-hydroperoxy-9,11-octadecanedienoyl)-lecithin (HpPLPC), PLPC provides insight into the impacts of oxidative stress on membrane integrity and functionality. -
Biochemical Reagent
1-Thio-β-D-glucose sodium is a biochemical reagent that exhibits self-assembling properties to form hydrophilic monolayers with metal surfaces. This compound stabilizes lipid bilayers, enhancing membrane integrity, and offers protection to proteins against denaturation. Its unique characteristics make it valuable in studies involving biomolecular interactions and membrane biophysics. -
Biochemical Assay Reagent
1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine derivative that serves as a key biochemical assay reagent. Its surfactant properties facilitate the formation of micelles, liposomes, and various artificial membranes. This compound is essential for studies involving membrane dynamics, drug delivery systems, and lipid-based nanocarrier development. -
Biochemical Assay Reagent
Cholesterol nervonate is a biochemical assay reagent that serves as a key organic compound in life science research. It is utilized for its role in studying lipid metabolism and membrane dynamics. This compound is valuable for various biological assays aimed at understanding cellular functions and the physiological effects of cholesterol-associated pathways. -
Biochemical Assay Reagent
LNP Lipid-48 is an SM-102 analog designed as a biochemical assay reagent for the formation of lipid nanoparticles (LNPs). It exhibits effective encapsulation properties, facilitating the delivery of nucleotides and other therapeutic agents. This reagent is crucial for research applications involving drug delivery systems and gene therapy development, enabling the advancement of mRNA-based therapeutics and vaccines. -
Biochemical Assay Reagent
Cholesterol hexanoate is an ester formed from the reaction of cholesterol and caproic acid. This compound serves as a biochemical assay reagent and exhibits bioactive properties, making it a valuable tool in pharmacological research. Its potential applications include studying cholesterol metabolism and addressing inflammation-related diseases. Additionally, cholesterol hexanoate can be explored for enhancing food texture and stability, contributing to various research initiatives. -
Biochemical Assay Reagent
3-Methylthymidine is a biochemical assay reagent that serves as a substrate for fat mass and obesity-associated protein (FTO). This compound is utilized in studies investigating FTO activity, particularly in the context of obesity and metabolic disorders. Its application in research can help elucidate the mechanisms by which FTO influences cellular processes related to fat metabolism and development. -
UDP-GalNAc Analog
UDP-GalNAz disodium is an analogue of UDP-GalNAc disodium, serving as a donor substrate for N-acetylgalactosaminyltransferases, which facilitate the transfer of GalNAc to various saccharide or peptide acceptors. This compound features an azide group, making it a valuable reagent for click chemistry applications. UDP-GalNAz disodium can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. It is useful in the study of glycosylation pathways and the synthesis of complex glycoproteins. -
Biochemical Assay Reagent
N-Isobutyryl-L-cysteine is a chiral derivatizing agent that facilitates the separation of amino acid enantiomers in biochemical assays. Its ability to react with amino acids enhances chromatographic resolution, making it an essential reagent in stereochemical analysis and purity assessment of chiral compounds. This reagent is valuable for researchers studying enantiomeric differences in various biological processes. -
Ester Product
Nervonate sodium is an ester compound known for its role in biochemical research. It serves as a valuable reagent for studies involving lipid metabolism and cellular signaling pathways. Its capacity to influence cellular functions makes it applicable in investigations of neurological processes and disorders.
