Catalog No.
Product Name
Application
Product Information
Citations
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Ziprasidone Impurity
Hydroxy ziprasidone is a known impurity of the antipsychotic agent ziprasidone, which functions primarily as a combined antagonist of both serotonin (5-HT) and dopamine receptors. This compound is useful for researchers studying the pharmacological properties and metabolic pathways of ziprasidone, as well as for quality control in the synthesis of pharmaceutical formulations. Its presence can provide insights into the drug's safety, efficacy, and potential side effects. -
Methotrexate Impurity
Methotrexate γ-Methyl Ester is an impurity of the folate antagonist Methotrexate, specifically identified as Methotrexate 5-methyl ester. This compound is utilized in chemical research to study the properties and potential effects of Methotrexate derivatives. It serves as a valuable tool for understanding the metabolism and biochemical activity of folate-related compounds in various biological systems. -
Biochemical Reagent
Diopterin is a folic acid analog that functions as a biochemical reagent. It exhibits potential inhibitory effects on dihydrofolate reductase, influencing folate metabolism. This compound is primarily utilized in leukemia research to investigate the role of folate in tumor biology and potential therapeutic strategies targeting folate metabolism in cancer cells. -
Impurity of Palbociclib
1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate is identified as an impurity of Palbociclib, a selective inhibitor of CDK4 and CDK6. This compound aids in the quality assessment of Palbociclib by providing insights into the synthesis and purification processes. Its analysis is crucial for ensuring the integrity and efficacy of CDK inhibition studies, primarily focusing on cell cycle regulation and cancer research applications. -
Impurity of Palbociclib
1,1-Dimethylethyl 4-(5-amino-3-pyridinyl)-1-piperazinecarboxylate is an identified impurity of Palbociclib, an orally administered selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4 and CDK6). Palbociclib demonstrates potent biological activity with IC50 values of 11 nM and 16 nM for CDK4 and CDK6, respectively. This reagent can be utilized in research to analyze the purity of Palbociclib and assess its pharmacological properties in cancer studies. -
Biochemical Reagent
Pyriprole is a biochemical reagent that primarily targets adult fleas, disrupting their life cycle by preventing reproduction. It exerts significant biological activity by killing adult fleas before they can lay eggs, thereby reducing the flea population. Additionally, Pyriprole has a residual effect on organic debris from dogs, which hinders the development of cat flea larvae into the adult stage. This makes Pyriprole a valuable tool for research into pest control and flea management strategies. -
Drug Intermediate
Propoxybenzene, also known as propyl phenyl ether, serves as a valuable dialkoxybenzene intermediate in chemical synthesis. This compound exhibits antiparasitic activity, making it particularly relevant in research focused on the control of Varroa mite infestations in apiculture. Its unique properties facilitate investigations into effective treatments for parasitic diseases affecting honeybee colonies. -
Ivermectin Impurity
2,3-Dehydro-3,4-dihydro ivermectin is an impurity of ivermectin, primarily exhibiting anthelmintic properties. It demonstrates anti-parasitic activity against Leishmania amazonensis promastigotes and amastigotes, with IC50 values of 13.8 µM and 3.6 µM, respectively. Importantly, this compound does not induce cytotoxicity in macrophages, with an IC50 of 65.5 µM, making it suitable for studies in parasitology and drug development research. -
Oseltamivir Impurity
Oseltamivir-acetate is an impurity associated with Oseltamivir, a well-known neuraminidase inhibitor utilized in the treatment and prevention of influenza A and B. This compound is valuable for research applications involving the analysis of Oseltamivir's purity and the study of its pharmacological properties in antiviral therapies. Understanding the presence of impurities like Oseltamivir-acetate can aid in the development of more effective influenza treatments and enhance the overall quality of the drug formulation. -
Biochemical Reagent
D-Carnitine is an isomer of the essential nutrient L-carnitine, functioning primarily as a biochemical reagent. It enhances the transport of long-chain fatty acids into the mitochondrial matrix, facilitating their beta-oxidation. Additionally, D-Carnitine exhibits antiparasitic activity, making it useful in various research applications related to metabolism and parasitology. -
Sofosbuvir Impurity
Sofosbuvir impurity G is a diastereoisomeric impurity of Sofosbuvir, which is a potent inhibitor of HCV RNA replication. This compound serves as an important reference standard for quality control and analytical purposes in the research and development of hepatitic C virus treatments. Its characterization is essential for understanding the processing and stability of Sofosbuvir formulations. -
Drug Intermediate
2'-Hydroxybiphenyl-3-carboxylic acid serves as a β-lactamase OXA-48 inhibitor, with an IC50 value of 50 µM and a Kd of 1750 µM. This compound is primarily utilized as a drug intermediate in the synthesis of therapeutics targeting antibiotic resistance. Its inhibitory properties make it valuable in studying the mechanisms and effects of β-lactamase enzymes in various biological contexts. -
Biochemical Assay Reagent
N-Phenylbenzamide is a biochemical assay reagent that functions primarily as a compound skeleton for various research applications. It demonstrates significant biological activity in studies related to cancer and infectious diseases, including enterovirus and cervical cancer. This compound is essential for exploring the underlying mechanisms of these conditions and developing potential therapeutic strategies. -
Biochemical Assay Reagent
(-)-Anicyphos is a chiral catalyst that enhances the selectivity of specific reactions in biochemical assays. This reagent is essential for the synthesis of complex chiral molecules in organic chemistry, demonstrating exceptional catalytic performance. By manipulating reaction conditions, (-)-Anicyphos can markedly improve the stereospecificity of products, making it a valuable tool for compound development in various research applications. -
Biochemical Assay Reagent
Bisphenol A bis(3-chloro-2-hydroxypropyl) ether is a biochemical assay reagent that exhibits potential antimicrobial activity. This compound is utilized to enhance the strength and durability of coatings and plastics, making it valuable in material science applications. Additionally, it contributes to textile processing by improving wrinkle and abrasion resistance in fabrics, supporting advancements in textile technology. -
Drug Intermediate
L-erythro-Chloramphenicol is a potent inhibitor of electron transport, primarily targeting mitochondrial function. Its significant biological activity makes it an important reagent in biochemical research relating to mitochondrial pathways and cellular respiration. This compound serves as a valuable intermediate in the synthesis of pharmaceutical agents and investigations involving antibiotic activity. -
Impurity of Lovastatin
Keto lovastatin is an impurity of Lovastatin that acts as an HMG-CoA reductase inhibitor. This compound exhibits antibacterial activity and is primarily utilized for research related to cholesterol synthesis and metabolic pathways. It serves as a crucial reference material in studies focused on Lovastatin and its derivatives, enhancing understanding of their pharmacological profiles. -
Clindamycin Impurity
Clindamycin 2,4-diphosphate is an impurity associated with Clindamycin phosphate, which is a prodrug of Clindamycin. Clindamycin phosphate functions by inhibiting protein synthesis through its interaction with the bacterial ribosomal 50S subunit. This compound is relevant for studies focused on antibiotic mechanisms, bacterial resistance, and the pharmacological characterization of clindamycin derivatives. -
Biochemical Assay Reagent
β-Sitosterol acetate, 40% (including Campesterol acetate) is a biochemical assay reagent utilized in various life science research applications. This compound serves as a biological material that aids in studies related to sterol metabolism, cellular signaling, and lipid biochemistry. Its role in biochemical assays makes it essential for exploring the physiological effects of sterols and their derivatives in cellular systems. -
Biochemical Reagent
CH-PIATA is a synthetic cannabinoid characterized by an acetamide linker, serving as a biochemical reagent in research applications. This compound exhibits potential biological activity, with EC50 values of >71 nM and >176 nM for cannabinoid receptors CB1 and CB2, respectively. CH-PIATA can be effectively detected as a parent substance in biological samples, making it a useful tool for studying cannabinoid receptor interactions and their physiological roles. -
Biochemical Assay Reagent
SFB-AMD3465 is a derivative of AMD3465, serving as a biochemical assay reagent. This compound functions as a positron emission tomography (PET) tracer for the chemokine receptor CXCR4 when labeled with radioactive fluorine. It is a valuable tool for exploring CXCR4-related signaling pathways and has applications in cancer research and imaging studies. -
Biochemical Reagent
Acein is a novel nonapeptide characterized by the sequence H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH, which primarily targets angiotensin-converting enzyme (ACE I). By promoting the release of dopamine, Acein plays a significant role in neurological research, particularly in studies related to neurotransmitter regulation. Its unique mechanism makes it a valuable tool for investigating the biochemical pathways associated with the nervous system. -
Olmesartan Impurity
Olmesartan impurity is a byproduct of olmesartan, an angiotensin II receptor (AT1R) antagonist. This reagent is important for quality control and analytical studies of olmesartan in pharmaceutical formulations. Additionally, it can be utilized in research related to hypertension treatment and cardiovascular disease studies, helping to elucidate the functional properties of olmesartan and its impurities. -
Biochemical Assay Reagent
ACEA (arachidonyl-2'-chloroacetamide) is a synthetic compound that acts as an agonist of the cannabinoid receptor CB1. It modulates the endocannabinoid system, influencing physiological processes including appetite regulation, pain perception, mood, and memory. This biochemical assay reagent is essential for research exploring the pharmacological effects and therapeutic potential of cannabinoid signaling. -
Biochemical Reagent
N,N-Dicyclohexylcarbodiimide (DCC) is a powerful biochemical reagent that functions as a dehydrating and condensing agent. It is primarily utilized to promote peptide coupling and enhance adenylate cyclase activity while inhibiting amine accumulation. DCC is commonly employed in the synthesis of 3-phenylcoumarin derivatives and the preparation of sulfated derivatives of purslane polysaccharides, making it an essential tool for researchers in organic and medicinal chemistry. -
Biochemical Assay Reagents
1-Bromo-2,5-pyrrolidinedione acts as a ligand for collagen proteins, serving as a valuable tool in biochemical assays. Its application extends to the investigation of wound healing-related diseases, facilitating insights into the mechanisms underlying tissue repair and regeneration. This compound is essential for researchers exploring therapeutic approaches to enhance wound healing processes. -
Drug Intermediate
2,4-Dichlorothieno[3,2-d]pyrimidine is a thienopyrimidine scaffold recognized as a crucial synthetic intermediate. It plays a significant role in the synthesis of 4-arylthieno[3,2-d]pyrimidine compounds, particularly in the development of human adenosine A2a receptor antagonists and PI3K-α inhibitors. Additionally, this compound shows potential for application in research related to whipworm disease, making it valuable for various biomedical investigations. -
Biochemical Assay Reagent
7-Methyladenosine perchlorate is a synthetic analog of adenosine that acts as an agonist at adenosine receptors. This compound effectively modulates cellular signaling pathways, making it a valuable reagent for investigating adenosine-related biological processes. Additionally, 7-Methyladenosine perchlorate holds potential as a tool in compound development, particularly as an inhibitor for biochemical assays. -
Phosphoramidite Compound
(S)-GNA-T-phosphoramidite is a phosphoramidite compound utilized in the synthesis of oligonucleotides. This reagent is essential for the construction of nucleic acid sequences in various research applications, including gene therapy, molecular diagnostics, and genetic engineering. Its reliable performance makes it an important tool in the field of synthetic biology and nucleic acid chemistry. -
Biochemical Assay Reagent
D-Galacto-D-mannan is a plant cell wall polysaccharide derived from Ceratonia siliqua, primarily utilized as a biochemical assay reagent. It demonstrates significant properties in biological applications, including its role in the study of cellular interactions and signaling pathways. This compound is particularly valuable in research focused on plant biology and cell wall characterization. -
Biochemical Assay Reagent
Adenosine 2'-PEG-Biotin is a biochemical assay reagent that acts as a bioisostere of endogenous adenosine, allowing it to engage adenosine receptors effectively. This compound plays a crucial role in regulating various cell signaling pathways, facilitating research into its applications as a bioprobe, biosensor, or diagnostic reagent. Its incorporation of biotin also enhances its utility in various biochemical assays and detection methodologies. -
Phosphoramidites
Bis(2-(trimethylsilyl)ethyl) diisopropylphosphoramidite is a phosphoramidite reagent designed for oligonucleotide synthesis. Its primary mechanism involves the introduction of phosphoramidite linkages in nucleic acid constructs. This compound is suitable for applications in molecular biology, including the development of DNA and RNA oligonucleotides for research in gene expression, antisense therapy, and RNA interference studies. -
Phosphoramidite Analogue
5'-DMT-5-F-2'-dU Phosphoramidite is a nucleoside phosphoramidite analogue designed for use in oligonucleotide synthesis. This compound facilitates the development of therapeutic oligonucleotides, with potential applications in creating drugs aimed at targeting various cancers. Its unique structure allows for incorporation into synthesized sequences, enhancing the efficacy of emerging RNA-based therapies. -
Diagnostic Imaging Agent
Etarfolatide is a noninvasive diagnostic imaging agent that targets folate receptor expression. Upon radiolabeling, it facilitates the visualization of tumors, making it particularly valuable in research related to ovarian cancer and disease diagnosis. Its application in imaging studies allows for better assessment of folate receptor status in various malignancies. -
Impurity of DM1
DM1 Impurity is a byproduct associated with the synthesis of Mertansine (DM1), a potent linker drug used in antibody-drug conjugates. This impurity is critical for analytical purposes, enabling researchers to assess the purity and stability of Mertansine formulations. Its identification and quantification are essential in ensuring the quality control of therapeutic agents that utilize DM1 in clinical applications. -
Phosphoramidite Derivative
DMT-2′Fluoro-dU Phosphoramidite is a phosphoramidite derivative of uridine with a fluorine atom at the 2' position. This reagent is designed for nucleoside modification, enabling the synthesis of modified DNA sequences. It is particularly useful in the development of oligonucleotides for applications in molecular biology and genetic research. -
Phosphoramidite Monomer
2'-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer designed for oligonucleotide synthesis. This compound incorporates a 2'-O-methyl group, which enhances the stability and hybridization properties of RNA oligonucleotides. It is particularly useful in studies involving RNA structure, function, and therapeutics, enabling researchers to create modified nucleic acids with improved pharmacological profiles. -
5-Fluoro-2'-deoxycytidine Phosphoramidite
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite functions as a phosphoramidite derivative of 5-fluoro-2'-deoxycytidine, specifically designed for use in solid-phase oligonucleotide synthesis. This reagent enables the incorporation of the nucleoside analogue into DNA sequences, facilitating studies of nucleotide metabolism, DNA repair mechanisms, and the effects of fluorinated nucleotides on enzyme activity. Its chemical structure allows for efficient coupling and enhances the stability of synthesized oligonucleotides, contributing to a range of molecular biology applications. -
Biochemical Assay Reagent
8,11,14-Eicosatriynoic Acid functions as a biochemical assay reagent primarily targeting the inhibition of prostaglandin and leukotriene biosynthesis. It effectively inhibits human 12-lipoxygenase (12-LO), cyclooxygenase (COX), and 5-lipoxygenase (5-LO) with IC50 values of 0.46 μM, 14 μM, and 25 μM, respectively. This compound also demonstrates inhibition of slow-reacting substances involved in allergic reactions, with an IC50 of 10 μM. Beyond its role in modulating inflammatory pathways, 8,11,14-Eicosatriynoic Acid serves as a click chemistry reagent due to its alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition. Its multifaceted applications are valuable in exploring disease mechanisms, particularly in cancer and oxidative stress conditions. -
Aceclofenac Impurity
Aceclofenac ethyl ester is an impurity of the non-steroidal anti-inflammatory drug Aceclofenac, primarily acting through inhibition of cyclooxygenase (COX) enzymes. This compound may serve as a reference standard in pharmacokinetic studies and method development for analyzing Aceclofenac and its related substances. Its characterization contributes to the understanding of the drug's stability and metabolism, aiding in the overall evaluation of therapeutic efficacy and safety profiles. -
Exenatide Impurity
(D-Asn28)-Exenatide is an impurity of Exenatide, which functions as a long-acting agonist of the glucagon-like peptide-1 receptor. This compound may be used in research applications focusing on peptide synthesis, quality control, and pharmacological studies involving GLP-1 receptor pathways. Its significance lies in understanding the properties and effects of Exenatide-related compounds. -
Budesonide Impurity
Budesonide impurity C is a known impurity associated with Budesonide, a potent inhaled corticosteroid that acts as an agonist of the glucocorticoid receptor. This impurity may play a role in studying the pharmacological profiles and quality control of Budesonide formulations. It is relevant for research applications involving drug stability, metabolism, and the assessment of therapeutic efficacy in inflammatory conditions. -
Prednisolone Impurity
Prednisolone valerate acetate is a known impurity of Prednisolone, a potent, orally active corticosteroid that primarily functions as a glucocorticoid. This compound is relevant for research focused on corticosteroid metabolism and any potential side effects associated with glucocorticoid therapies. Its presence may be significant in the analysis of pharmaceutical formulations containing Prednisolone and supports studies investigating corticosteroid-related biological activity. -
Impurity
6-Iododiosmin is a known impurity of Diosmin, serving as a reference standard for the characterization of Diosmin-related compounds. It is essential for quality control in pharmaceutical formulations and research involving Diosmin's therapeutic applications. This compound aids in the investigation of the chemical behavior and biological properties of Diosmin, thereby enhancing the understanding of its efficacy and safety profiles. -
Ibuprofen Impurity
p-Ethylhydratropic acid is identified as a notable impurity found in ibuprofen, which functions as a potent and selective inhibitor of cyclooxygenase-1 (COX-1). Its presence in pharmaceutical formulations is significant for quality control and analytical studies. Research applications may include the characterization of ibuprofen derivatives and the investigation of their respective pharmacological profiles. -
Impurity
11β-Misoprostol is an impurity derived from the synthesis of Misoprostol, a 15-deoxy-16-hydroxy-16-methyl analog of prostaglandin E1 (PGE1). Its structural characteristics may be important in assessing the quality and purity of Misoprostol preparations. Researchers may utilize 11β-Misoprostol in analytical studies focused on impurity profiling and quality control within pharmaceutical formulations. -
Impurity
Isopropyl 5-(diphenylphosphoryl)pentanoate is an impurity associated with Latanoprost, a prostaglandin analog used in the treatment of glaucoma. This compound serves as a reference material for assessing the purity and quality of Latanoprost formulations. Its presence and characterization are critical for regulatory compliance and ensuring product safety in pharmaceutical research and development. -
Clopidogrel Impurity
Clopidogrel-related Compound B hydrochloride is an impurity of Clopidogrel, functioning as a pharmacological marker in analytical applications. Its presence is an important consideration in the assessment of Clopidogrel purity and efficacy. This compound is primarily utilized in pharmaceutical research to ensure the quality and consistency of Clopidogrel formulations. -
Drug Intermediate
Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes. -
Impurity of Darifenacin
(±)-Darifenacin N-Oxide is an impurity of the selective M3 muscarinic receptor antagonist Darifenacin. This compound may serve as a reference standard in analytical chemistry and pharmacological studies involving Darifenacin. Its characterization is crucial for ensuring the purity and efficacy of Darifenacin in various research applications.
