Catalog No.
Product Name
Application
Product Information
Citations
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Biochemical Assay Reagent
Bromothymol Blue sodium is a pH indicator that exhibits color changes in the range of pH 6.0 to 7.6. It is commonly utilized in biochemical assays for titrations and detection of pH variations in various experimental conditions. This reagent enables the visualization of pH fluctuations, making it indispensable in laboratory settings for acid-base studies. It is recommended to store the reagent protected from light to maintain its integrity. -
Biochemical Assay Reagent
5,5'-Dibromo-BAPTA is a calcium chelator that selectively binds to Ca2+ ions, thereby modulating calcium-dependent processes. This compound is widely utilized in biochemical assays to investigate calcium signaling pathways and to study cellular responses to changes in intracellular calcium levels. Its efficacy in inhibiting calcium-mediated events makes it a valuable tool in research applications spanning neuroscience, cell biology, and pharmacology. -
Biochemical Assay Reagent
Pyrene azide 2 is a fluorescent compound designed as a biochemical assay reagent. Featuring a pyrene moiety linked by a PEG2 unit, it enhances water solubility, making it suitable for various biological applications. This compound is ideal for studies involving fluorescence-based detection and can be employed in assays to investigate biomolecular interactions and cellular processes. -
Biochemical Reagent
Diopterin is a folic acid analog that functions as a biochemical reagent. It exhibits potential inhibitory effects on dihydrofolate reductase, influencing folate metabolism. This compound is primarily utilized in leukemia research to investigate the role of folate in tumor biology and potential therapeutic strategies targeting folate metabolism in cancer cells. -
Impurity of Palbociclib
1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate is identified as an impurity of Palbociclib, a selective inhibitor of CDK4 and CDK6. This compound aids in the quality assessment of Palbociclib by providing insights into the synthesis and purification processes. Its analysis is crucial for ensuring the integrity and efficacy of CDK inhibition studies, primarily focusing on cell cycle regulation and cancer research applications. -
Impurity of Palbociclib
1,1-Dimethylethyl 4-(5-amino-3-pyridinyl)-1-piperazinecarboxylate is an identified impurity of Palbociclib, an orally administered selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4 and CDK6). Palbociclib demonstrates potent biological activity with IC50 values of 11 nM and 16 nM for CDK4 and CDK6, respectively. This reagent can be utilized in research to analyze the purity of Palbociclib and assess its pharmacological properties in cancer studies. -
Drug Intermediate
1,3-Dihydroxyacetone (DHA) serves as an essential drug intermediate and is primarily recognized for its role in sunless tanning skin-care formulations. It is produced industrially through the microbial fermentation of glycerol, particularly using Gluconobacter oxydans. Additionally, 1,3-Dihydroxyacetone is valuable in the synthesis of novel biodegradable polymers when reacted with lactic acid, enhancing its utility in various biochemical and material science applications. -
Biochemical Assay Reagent
Methotrexate hydrate is a potent inhibitor of dihydrofolate reductase, targeting folate metabolism to disrupt DNA synthesis and cellular proliferation. This reagent is widely utilized in biochemical assays, particularly in cancer research and the treatment of autoimmune disorders, to examine cell growth, division, and response to therapy. Its mechanism of action provides a critical tool for investigating cellular processes and therapeutic efficacy in various disease models. -
Biochemical Assay Reagents
Tetrasodium pyrophosphate is a chelating agent that primarily targets calcium ions, enhancing olfactory function. In addition, it exhibits antimicrobial properties that can effectively reduce microbial colonization in various biological systems. This compound is widely utilized in biochemical assays and life science research applications, including investigations related to post-COVID-19 symptom alleviation. Its versatile nature makes it a valuable tool for researchers exploring diverse biochemical pathways. -
Biochemical Assay Reagent
Adenosine 2'-PEG-Biotin is a biochemical assay reagent that acts as a bioisostere of endogenous adenosine, allowing it to engage adenosine receptors effectively. This compound plays a crucial role in regulating various cell signaling pathways, facilitating research into its applications as a bioprobe, biosensor, or diagnostic reagent. Its incorporation of biotin also enhances its utility in various biochemical assays and detection methodologies. -
Phosphoramidites
Bis(2-(trimethylsilyl)ethyl) diisopropylphosphoramidite is a phosphoramidite reagent designed for oligonucleotide synthesis. Its primary mechanism involves the introduction of phosphoramidite linkages in nucleic acid constructs. This compound is suitable for applications in molecular biology, including the development of DNA and RNA oligonucleotides for research in gene expression, antisense therapy, and RNA interference studies. -
Phosphoramidite Analogue
5'-DMT-5-F-2'-dU Phosphoramidite is a nucleoside phosphoramidite analogue designed for use in oligonucleotide synthesis. This compound facilitates the development of therapeutic oligonucleotides, with potential applications in creating drugs aimed at targeting various cancers. Its unique structure allows for incorporation into synthesized sequences, enhancing the efficacy of emerging RNA-based therapies. -
Biochemical Reagent
Acein is a novel nonapeptide characterized by the sequence H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH, which primarily targets angiotensin-converting enzyme (ACE I). By promoting the release of dopamine, Acein plays a significant role in neurological research, particularly in studies related to neurotransmitter regulation. Its unique mechanism makes it a valuable tool for investigating the biochemical pathways associated with the nervous system. -
Olmesartan Impurity
Olmesartan impurity is a byproduct of olmesartan, an angiotensin II receptor (AT1R) antagonist. This reagent is important for quality control and analytical studies of olmesartan in pharmaceutical formulations. Additionally, it can be utilized in research related to hypertension treatment and cardiovascular disease studies, helping to elucidate the functional properties of olmesartan and its impurities. -
Biochemical Assay Reagent
ACEA (arachidonyl-2'-chloroacetamide) is a synthetic compound that acts as an agonist of the cannabinoid receptor CB1. It modulates the endocannabinoid system, influencing physiological processes including appetite regulation, pain perception, mood, and memory. This biochemical assay reagent is essential for research exploring the pharmacological effects and therapeutic potential of cannabinoid signaling. -
Biochemical Reagent
N,N-Dicyclohexylcarbodiimide (DCC) is a powerful biochemical reagent that functions as a dehydrating and condensing agent. It is primarily utilized to promote peptide coupling and enhance adenylate cyclase activity while inhibiting amine accumulation. DCC is commonly employed in the synthesis of 3-phenylcoumarin derivatives and the preparation of sulfated derivatives of purslane polysaccharides, making it an essential tool for researchers in organic and medicinal chemistry. -
Drug Intermediate
2,4-Dichlorothieno[3,2-d]pyrimidine is a thienopyrimidine scaffold recognized as a crucial synthetic intermediate. It plays a significant role in the synthesis of 4-arylthieno[3,2-d]pyrimidine compounds, particularly in the development of human adenosine A2a receptor antagonists and PI3K-α inhibitors. Additionally, this compound shows potential for application in research related to whipworm disease, making it valuable for various biomedical investigations. -
Biochemical Assay Reagent
7-Methyladenosine perchlorate is a synthetic analog of adenosine that acts as an agonist at adenosine receptors. This compound effectively modulates cellular signaling pathways, making it a valuable reagent for investigating adenosine-related biological processes. Additionally, 7-Methyladenosine perchlorate holds potential as a tool in compound development, particularly as an inhibitor for biochemical assays. -
Phosphoramidite Compound
(S)-GNA-T-phosphoramidite is a phosphoramidite compound utilized in the synthesis of oligonucleotides. This reagent is essential for the construction of nucleic acid sequences in various research applications, including gene therapy, molecular diagnostics, and genetic engineering. Its reliable performance makes it an important tool in the field of synthetic biology and nucleic acid chemistry. -
Biochemical Assay Reagent
D-Galacto-D-mannan is a plant cell wall polysaccharide derived from Ceratonia siliqua, primarily utilized as a biochemical assay reagent. It demonstrates significant properties in biological applications, including its role in the study of cellular interactions and signaling pathways. This compound is particularly valuable in research focused on plant biology and cell wall characterization. -
Biochemical Assay Reagents
1-Bromo-2,5-pyrrolidinedione acts as a ligand for collagen proteins, serving as a valuable tool in biochemical assays. Its application extends to the investigation of wound healing-related diseases, facilitating insights into the mechanisms underlying tissue repair and regeneration. This compound is essential for researchers exploring therapeutic approaches to enhance wound healing processes. -
Biochemical Assay Reagent
β-Sitosterol acetate, 40% (including Campesterol acetate) is a biochemical assay reagent utilized in various life science research applications. This compound serves as a biological material that aids in studies related to sterol metabolism, cellular signaling, and lipid biochemistry. Its role in biochemical assays makes it essential for exploring the physiological effects of sterols and their derivatives in cellular systems. -
Biochemical Reagent
CH-PIATA is a synthetic cannabinoid characterized by an acetamide linker, serving as a biochemical reagent in research applications. This compound exhibits potential biological activity, with EC50 values of >71 nM and >176 nM for cannabinoid receptors CB1 and CB2, respectively. CH-PIATA can be effectively detected as a parent substance in biological samples, making it a useful tool for studying cannabinoid receptor interactions and their physiological roles. -
Biochemical Assay Reagent
SFB-AMD3465 is a derivative of AMD3465, serving as a biochemical assay reagent. This compound functions as a positron emission tomography (PET) tracer for the chemokine receptor CXCR4 when labeled with radioactive fluorine. It is a valuable tool for exploring CXCR4-related signaling pathways and has applications in cancer research and imaging studies. -
Oseltamivir Impurity
Oseltamivir-acetate is an impurity associated with Oseltamivir, a well-known neuraminidase inhibitor utilized in the treatment and prevention of influenza A and B. This compound is valuable for research applications involving the analysis of Oseltamivir's purity and the study of its pharmacological properties in antiviral therapies. Understanding the presence of impurities like Oseltamivir-acetate can aid in the development of more effective influenza treatments and enhance the overall quality of the drug formulation. -
Biochemical Reagent
D-Carnitine is an isomer of the essential nutrient L-carnitine, functioning primarily as a biochemical reagent. It enhances the transport of long-chain fatty acids into the mitochondrial matrix, facilitating their beta-oxidation. Additionally, D-Carnitine exhibits antiparasitic activity, making it useful in various research applications related to metabolism and parasitology. -
Sofosbuvir Impurity
Sofosbuvir impurity G is a diastereoisomeric impurity of Sofosbuvir, which is a potent inhibitor of HCV RNA replication. This compound serves as an important reference standard for quality control and analytical purposes in the research and development of hepatitic C virus treatments. Its characterization is essential for understanding the processing and stability of Sofosbuvir formulations. -
Drug Intermediate
2'-Hydroxybiphenyl-3-carboxylic acid serves as a β-lactamase OXA-48 inhibitor, with an IC50 value of 50 µM and a Kd of 1750 µM. This compound is primarily utilized as a drug intermediate in the synthesis of therapeutics targeting antibiotic resistance. Its inhibitory properties make it valuable in studying the mechanisms and effects of β-lactamase enzymes in various biological contexts. -
Biochemical Assay Reagent
N-Phenylbenzamide is a biochemical assay reagent that functions primarily as a compound skeleton for various research applications. It demonstrates significant biological activity in studies related to cancer and infectious diseases, including enterovirus and cervical cancer. This compound is essential for exploring the underlying mechanisms of these conditions and developing potential therapeutic strategies. -
Biochemical Assay Reagent
(-)-Anicyphos is a chiral catalyst that enhances the selectivity of specific reactions in biochemical assays. This reagent is essential for the synthesis of complex chiral molecules in organic chemistry, demonstrating exceptional catalytic performance. By manipulating reaction conditions, (-)-Anicyphos can markedly improve the stereospecificity of products, making it a valuable tool for compound development in various research applications. -
Biochemical Assay Reagent
Bisphenol A bis(3-chloro-2-hydroxypropyl) ether is a biochemical assay reagent that exhibits potential antimicrobial activity. This compound is utilized to enhance the strength and durability of coatings and plastics, making it valuable in material science applications. Additionally, it contributes to textile processing by improving wrinkle and abrasion resistance in fabrics, supporting advancements in textile technology. -
Drug Intermediate
L-erythro-Chloramphenicol is a potent inhibitor of electron transport, primarily targeting mitochondrial function. Its significant biological activity makes it an important reagent in biochemical research relating to mitochondrial pathways and cellular respiration. This compound serves as a valuable intermediate in the synthesis of pharmaceutical agents and investigations involving antibiotic activity. -
Impurity of Lovastatin
Keto lovastatin is an impurity of Lovastatin that acts as an HMG-CoA reductase inhibitor. This compound exhibits antibacterial activity and is primarily utilized for research related to cholesterol synthesis and metabolic pathways. It serves as a crucial reference material in studies focused on Lovastatin and its derivatives, enhancing understanding of their pharmacological profiles. -
Clindamycin Impurity
Clindamycin 2,4-diphosphate is an impurity associated with Clindamycin phosphate, which is a prodrug of Clindamycin. Clindamycin phosphate functions by inhibiting protein synthesis through its interaction with the bacterial ribosomal 50S subunit. This compound is relevant for studies focused on antibiotic mechanisms, bacterial resistance, and the pharmacological characterization of clindamycin derivatives. -
MOF
4,6-Dioxoheptanoic acid is an inhibitor of heme biosynthesis, specifically targeting the biosynthetic pathway of porphyrins. It exhibits biological activity by interfering with key enzymatic processes involved in heme formation. This compound is useful in studies related to iron metabolism, porphyrias, and the regulation of heme-dependent enzymes in various biological contexts. Its application in chemical research provides valuable insight into metabolic regulation and related disorders. -
Biochemical Reagent
Citrate synthase is an essential enzyme that catalyzes the initial step of the citric acid cycle, facilitating the condensation of acetyl-CoA and oxaloacetate to produce citrate. This enzyme is primarily located in the mitochondrial matrix of eukaryotic cells. Citrate synthase plays a crucial role in cellular metabolism and energy production, making it a valuable biochemical reagent for research applications related to metabolic pathways and mitochondrial function. -
Biochemical Assay Reagent
β-D-Glucose is a monosaccharide that serves as a primary energy source for cells and plays a crucial role in various metabolic pathways. Its chemical properties allow it to be a significant component in both plant and animal tissues, where it is easily metabolized to produce cellular energy. In research applications, β-D-Glucose is utilized as a biochemical assay reagent and serves essential roles in studying metabolic processes, cell culture, and energy production mechanisms. -
MOF
Glutaric acid, a C5 dicarboxylic acid, serves as a key intermediate in the catabolic pathways of lysine and tryptophan. It plays a critical role in influencing pericyte contractility and migration, thereby impacting vascular dynamics. In addition, glutaric acid is recognized as a biomarker in the diagnosis of glutaric aciduria type I, making it relevant for studies in metabolic disorders and related pathways. -
Biochemical Assay Reagent
Fumaric acid disodium, a biochemical assay reagent, serves as a crucial tool in various life science research applications. This compound is utilized for its role in metabolic processes, enabling investigations into biochemical pathways and cellular functions. Its ability to modulate enzymatic activity makes it an essential component for experimental setups aimed at understanding metabolic disorders and cellular metabolism. -
Biochemical Reagent
(S)-2-Aminohexanedioic acid is a biochemical reagent primarily utilized in life science research as a building block in the synthesis of peptides and other organic compounds. This compound plays a crucial role in studies involving amino acid metabolism and protein function. Its application extends to various biochemical assays and experimental models aimed at understanding metabolic pathways and cellular processes. -
Drug Intermediate
m-Tolylacetic acid, also known as 3-Methylbenzeneacetic acid, serves as a hydroaromatic dicarboxylic acid and is commonly found as a metabolite of tolueneacetic acid in urine. This compound is primarily utilized as a drug intermediate, facilitating the synthesis of more complex organic molecules in pharmaceutical research. Its unique structure makes it a valuable component in the development of various bioactive compounds. -
Eszopiclone Impurity
RP 48497 is a photodegradation product and impurity of Eszopiclone, a non-benzodiazepine compound utilized in the management of insomnia. This compound serves as a valuable tool in pharmaceutical research and quality control, aiding in the assessment of Eszopiclone's stability and purity. Its analysis can contribute to a deeper understanding of the drug's degradation pathways and potential effects on efficacy and safety. -
Fexofenadine Impurity
Meta-Fexofenadine is a known impurity of Fexofenadine, which serves as an antihistamine by targeting the H1 receptor (H1R) and is primarily utilized for the treatment of allergic conditions such as seasonal allergic rhinitis and chronic idiopathic urticarial. This compound can be critical for analytical research, particularly in the study of drug purity, metabolic pathways, and formulation development. Its presence is significant in ensuring the quality and safety of Fexofenadine-based therapeutic products. -
Nifedipine Impurity
m-Nifedipine is an impurity associated with Nifedipine, a well-known calcium channel blocker. Nifedipine primarily targets L-type calcium channels, resulting in the relaxation of vascular smooth muscle, which is beneficial in the treatment of cardiac insufficiencies and hypertension. The study of m-Nifedipine may provide insights into the stability, quality, and potential side effects of Nifedipine formulations in pharmaceutical research. -
Impurity of Methotrexate
1,1,3-Tribromoacetone is identified as an impurity of Methotrexate, an established antimetabolite and antifolate that targets dihydrofolate reductase. By inhibiting this enzyme, Methotrexate effectively disrupts the conversion of folic acid to tetrahydrofolate, leading to a significant reduction in DNA synthesis. This compound can be utilized in the study of Methotrexate's pharmacological profiles and potential impurities in biological research. -
Biochemical Assay Reagent
2-(Benzhydrylsulfinyl)acetic acid is a biochemical assay reagent and a known metabolite of modafinil. This compound serves as a useful tool for studying metabolic pathways and pharmacokinetics of modafinil and related compounds. Its unique chemical structure can aid in investigations related to neurotransmitter regulation and cognitive enhancement research. -
Impurity of Palbociclib
N-Methyl Palbociclib is an impurity of Palbociclib, a selective inhibitor of CDK4 and CDK6. This compound is primarily used in analytical studies to assess the purity and quality of Palbociclib formulations. Its relevance in research includes characterization of CDK inhibition and investigations into cell cycle regulation in cancer therapy. -
Impurity of Febuxostat
Febuxostat amide impurity is a known impurity associated with the compound Febuxostat, a selective xanthine oxidase inhibitor that exhibits a Ki of 0.6 nM. The presence of this impurity can be significant for analytical applications and the assessment of the purity in pharmaceutical formulations. It serves as an important reference material for researchers investigating the chemical integrity and efficacy of xanthine oxidase inhibitors in various biological contexts. -
Osimertinib Mesylate Impurity
Rezivertinib analogue 1 is recognized as a process impurity of osimertinib mesylate, a potent inhibitor of EGFR mutations. This compound serves as a valuable tool in the research of non-small cell lung cancer, facilitating the investigation of drug efficacy and safety profiles in therapeutic applications. Its role in characterizing impurities enhances understanding of the pharmacological landscape surrounding osimertinib-related treatments. -
Labetalol Impurity
Labetalone hydrochloride is an impurity of Labetalol, an orally active adrenoceptor blocking agent. It functions as a competitive antagonist at both alpha- and beta-adrenoceptor sites, contributing to the pharmacological profile of Labetalol. This compound is primarily used in research applications related to cardiovascular pharmacology and the study of adrenoceptor interactions.
