Pemetrexed disodium hemipenta hydrate

Catalog No.: A15207

Pemetrexed disodium hemipenta hydrate

Pemetrexed disodium hemipenta hydrate Chemical Structure

CAS NO. 357166-30-4

Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.

Availability: In stock

Package Price Qty
1000 mg
$130.00
5000 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
Targets
TS TS DHFR DHFR GARFT
1.3 nM1.3 nM(Ki)7.2 nM7.2 nM(Ki)65 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.74 mL 213.48 mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.13 mL 10.67 mL 21.35 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15207
Actions No
M. Wt 468.42
Formula C20H23N5NaO7+
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 357166-30-4
Synonyms Pemetrexed sodium hydrate (1:2:2.5)
SMILES C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]

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