PF-03084014

Catalog No.: A11259

γ-secretase inhibitor

PF-03084014

PF-03084014 Chemical Structure

CAS NO. 865773-15-5, 1290543-63-3

PF-03084014 is a reversible and selective inhibitor of γ-secretase with IC50 value of 6.2 nM .

Availability: In stock

Package Price Qty
5 mg
$105.00
10 mg
$179.00
25 mg
$315.00
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Biological Activity

PF-03084014 is a reversible and selective inhibitor of γ-secretase with IC50 value of 6.2 nM .
In vitro DMSO Warmed: 89 mg/mL (181.76 mM)
Water Insoluble
Ethanol Warmed: 89 mg/mL (181.76 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.42 mL 102.12 mL 204.23 mL
0.5 mM 4.08 mL 20.42 mL 40.85 mL
1 mM 2.04 mL 10.21 mL 20.42 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 489.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11259
Actions Inhibitor
CAS No. 865773-15-5, 1290543-63-3
Formula C27H41F2N5O
M. Wt 489.64
Purity >98%
Synonyms PF 03084014, PF03084014
SMILES CCC[[email protected]@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[[email protected]]2CCC3=CC(=CC(=C3C2)F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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