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PIK-III

Autophagy Inhibitor

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Catalog No. A15868

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PIK-III 5mg A15868-5
$130.00
PIK-III 10mg A15868-10
$210.00
PIK-III 25mg A15868-25
$470.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PIK-III is a selective inhibitor of VPS34 enzymatic activity.

PIK-III

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Chemical Information

Catalog Num A15868
Actions Inhibitor
M. Wt 319.36
Formula C17H17N7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1383716-40-2
Synonyms VPS34-IN2
SMILES NC1=NC=C(C2=NC(NC3=CC=NC=C3)=NC=C2)C(CC4CC4)=N1

Biological Activity

Description
PIK-III is a selective inhibitor of VPS34 enzymatic activity.
Targets
Target Value
Vps34IC50: 0.018μM
PI3KδIC50: 1.2μM
PI3KγIC50: 3.04μM
PI3KαIC50: 3.96μM
PI4KβIC50: 4.43μM
PI3KβIC50: >9.1μM
mTORIC50: >9.1μM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.31 mL 156.56 mL 313.13mL
0.5 mM 6.26 mL 31.31 mL 62.63 mL
1 mM 3.13 mL 15.66 mL 31.31 mL
5 mM 0.63 mL 3.13 mL 6.26 mL

*The above data is based on the productmolecular weight 319.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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